膈下逐瘀湯과 膈下逐瘀湯合四君子湯의 抗癌 및 免疫調節作用에 關한 實驗的 硏究

崔昇勳,安圭錫,文濬典,高光錫 대한동의병리학회 1994 동의생리병리학회지 Vol.9 No.1

연구배경 : 암은 사망의 주요 원인이 되는 질환으로 매년 증가하고 있는 추세이다. 이에 mouse에 암을 유발하여, 약물치료를 시행함으로써 높은 치료효과를 거두는 한약제재를 개발하여 암의 치료에 기여하고 아울러 근본적인 예방치료에 대한 새로운 방법을 제시하고자 함. 방법 : 생쥐에 Sacroma 180을 이식하여 복강암을 유발하고 격하축어탕 및 격하축어탕합사군자탕을 투여하여 생명연장률과 B cell 및 T cell, 혈청항체가, 임파구증식반응, IL-2 생산능 및 자연살해페소의 활성도를 측정하였다. 결과 : 격하축어탕과 격하축어탕합사군자탕은 면역조절작용을 통한 항암효과가 있을 것으로 생각되며, 활혈거어제인 격하축어탕과 보기제인 사군자탕을 합방했을때, 그 효과가 증가되었다. In order to investigate the effects of Gyeokhachukeotang and Gyeokhachukeotang plus Sagunjatang on anti-tumor and immunodulatory reaction to the ICR and C57BL/6 mice which have abdominal tumor after Sarcoma-180 cells were transplanted, the extracts of herbal medicines above mentioned were orally administered to the mice for 21 days to observe the extention of survival duration of the mice, quantitation of T cells and B cells, productivitiy of interleukin-2, lymphocytes transformation, hemagglutinin titer and hemolysin titer and activity of splenic natural killer cells. The results are summarized as follows; 1. In the effect of life extention, the Gyeokhachukeotang-medicated mice group inclined to show extended duration of life, which is of no great significant difference and the mice group medicated with mixture of Gyeokhachukeotang plus Sagunjatang appeared to survive longer than the Gyeokhachukeotang-medicated mice group, which is not meaningful. 2. Considering T cell and B cell content, the Gyeokhachukeotang-medicated mice group had a meaningful increase in B cell (P<0.05) content, and the mice group medicated with the mixture of Gyeokhachukeotang plus Sagunjatang remarkably showed a significant increase in both T cell and B cell (P<0.01). 3. Considering serum antibody titer tended to increase in case of the Gyeokhachukeotang-medicated mice group, which is of no significant difference, while decreasing in case of the mice group medicated with mixture of Gyeokhachukeotang plus Sagunjatang. 4. In lymphocyte transformation marked a significant increase the Gyeokhachukeotang-medicated mice group, marked a significant (P<0.01), and remarkably showed a significant increase the mice group medicated with the mixture of Gyeokhachukeotang plus Sagunjatang (P<0.001). 5. As for the productivity of interleukin-2 and the activity of NK cells, the both tested groups inclined to show an increase or a decrese, but there is no significance.

편심하중을 받는 상자형의 단면변형에 관한 연구

鄭熺孝,安光列,金鎬洙,黃俊碩 경상대학교 생산기술연구소 2001 工學硏究院論文集 Vol.1 No.-

Eccentric load acts on box girder is divided into bending and torsional load and deforms cross section. Distortion that is resulted from torsional load is largely different according to tickness of each plate or stiffener. According to with and without regard of distorsion effect, it is possible to divide analysis of box gilder into two. First, analysis of box gilder can be able to calcurate with rigid box girder in assumption that there is no distorsion when the girder is well stiffened with diaphragms or cross bracing and plate thickness of box section is thick. Second is the analysis that must be considered effect of distorsion when the girder has not sufficient stiffener or plate thickness of box section is not well thick. In numerical example of this study, normal stress of rigid cross section analysis is compared with that of deformable cross section analysis without interior diaphragms. Then, it was studied that stresses of the deformable cross section analysis can be near rigid analysis when box girder was stiffened with interior diaphragms.

웨이브릿 변환에 기반한 적응 음향반향제거

류권열,안주원,문광석 釜慶大學校 1999 釜慶大學校 論文集 Vol.4 No.1

In this paper, an adaptive acoustic echo canceller based on the wavelet transform filter banks is proposed. The proposed algorithm improves the performance of AEC with a realtime process. The conjugate quadrature filter by Daubechies D4 wavelet is used for proposed wavelet subband filter banks. Adaptive filter coefficients of each subband are updated using LMS algorithm. Subband output signal vectors of adaptive filter are synthesized by synthesis filter banks. The output of adaptive filter is obtained a widband characteristics. As a result of computer simulation using the practical speech signal, the proposed method reduces noise level about l6dB.

자연임신에서 분만 및 주산기 예후에 대한 임상적 고찰

이윤희,안준모,김태성,박은희,정집광,이석민,이해혁 순천향의학연구소 2002 Journal of Soonchunhyang Medical Science Vol.8 No.1

Object: To compare pregnancy outcome between term pregnancy and postterm pregnancy. Method: A clinical observation has been made on 60 cases of postterm pregnancies out of 64 cases delivered at the Dept. of Obstetrics & Gynecology, Soonchunhyang University from January 1, 1997 to May 31, 2002. 100 cases of full term deliveries of 37 to 42 gestational weeks conducted in same period were used as the control group for this study. We analyzed their cesarean section rate, fetal weight, placental weight, meconium stain, perinatal morbidity. The statistical significance was defined as P<0.05. Result: The following results were obtained 1. The incidence of postterm pregnancy was 1.34%. 2. The cesarean delivery rate in postterm group(51.7%) was significantly higher than control group(26%). 3. The incidence of large fetus (weight over 4,000gm) in the postterm group(21.7%) was higher than control group(2%). 4. The weight of placenta was 757g and 706g in the postterm group and control group respectively. 5. 1, 5 minute Apgar score lower in the postterm group than control group. Conclusion : To decrease perinatal morbidity and cesarean rate at 42 or more weeks gestation, appropriate labor induction and twice weekly biophysical profile and USF(AI, Doppler) may be indicated.

Poster Session 2 : Apoptosis and Cell Cycle Oncogenes and Tumor Suppressor Genes ; Platycodin D-induced NF-kB activation and apoptosis in immortalized keratinocytes

( Kwang Seok Ahn ),( Bum Soo Hahn ),( Kyu Bum Kwack ),( Eun Bang Lee ),( Yeong Shik Kim ) 한국생화학분자생물학회 (구 한국생화학회) 2004 생화학분자생물학회 춘계학술발표논문집 Vol.2004 No.-

Clinical Analysis on Ectopic Pregnancy

Ahn, Chi Seok,Ahn, Kwang Hwa,Lee, Pyl Ryang,Kim, Hak Soon 충북대학교 의과대학 충북대학교 의학연구소 1994 忠北醫大學術誌 Vol.4 No.1

자궁외 임신은 임상에서 비교적 익숙하게 접하는 질환으로 그 중요성에도 불구하고 본원의 사정상 경험이 극히 제한된 실정이다. 자궁외 임신의 진단 및 치료에 대한 최근의 괄목할 만한 발전으로 각 병원의 다양한 임상 경험 및 충분한 자료의 축적이 요구되고 있다. 비록 제한된 관찰이긴 하나 자궁외임신의 일반적인 임상 양상을 이해하고 향후에 보다 광범위한 분석을 계획하고자 그 기본 자료로써 본원 개원 이후 본 교실에서 경험하고 성공적인 치료가 되었던 35예의 자궁외 임신을 환자의 임상, 수술 소견에 따라 분석하였다. Despite of numerous reports on ectopic pregnancy in other hospitals, we have still extremely limited experiences. The recent advances in diagnosis and treatment of ectopic pregnancy urge us to found on our own basic database. For the purpose of this, we analyzed the clinical characteristics of thirty-five ectopic pregnancies treated at our hospital. Although it is very limited observations, yet we hope to understand the nature of ectopic pregnancy and construct the extended findings in future.

Rapid canine retraction in a Class II bialveolar protrusion case using a lingually extended distraction screw

Kwang-Seok Ahn(안광석),Euk Joo(주억),Ju-Young Park(박주영),Young-Kyu Ryu(유영규),In-Ho Cha(차인호),Kee-Joon Lee(이기준) 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.4

Rapid canine retraction in a Class II bialveolar protrusion case using a lingually extended distraction screw

Ahn, Kwang-Seok,Joo, Euk,Park, Ju-Young,Ryu, Young-Kyu,Cha, In-Ho,Lee, Kee-Joon 대한치과교정학회 2006 대한치과교정학회지 Vol.36 No.4

Rapid canine retraction, first introduced by Liou, is a distraction osteogenesis applied to the periodontal ligament tissue. Rapid tooth movement was facilitated by establishing minimal bony resistance on the distal surface of the canine by socket preparation and by osteogenesis on the mesial side in response to the periodontal distraction. Since undesired buccal tipping or extrusion of the canine during retraction tends to occur, it is crucial to maintain the firm path of movement and the axis of the canine during retraction. In order to improve the predictability of the canine movement, lingually extended distraction screws with heavy labial guiding wires were designed. Prefabricated plastic canine models for the estimation of socket depth and miniscrew implants for anchorage reinforcement were also devised. Applying these devices to a female patient with Class II anterior protrusion, the whole treatment was effectively finished in 13 months. Loss of vitality or periodontal problems did not occur throughout treatment, and stable occlusion was maintained during 10 months of retention. This case report demonstrates that a predictable rapid canine retraction can be achieved through the use of this modified technique. 견인골 신장술의 개념을 치주인대 조직에 적용한 Liou의 급속 치아 이동 술식은 이동할 견치의 원심부 골 삭제에 의한 치조골 저항의 최소화 및 근심부의 치주조직 견인에 의한 골 형성으로 요약된다. 이는 주로 제1소구치 발치 후 견치의 견인을 요하는 환자들에 적용되어 효과적으로 치료 기간을 단축하고 양호한 결과를 얻을 수 있으나 견인 중 견치의 경사 및 정출 등 문제점이 발생하기 쉬우므로 견인이 완료될 때까지 치체이동을 유도하며 경로를 유지하는 것이 중요하다. 본 증례에서는 이러한 급속견인의 예측가능성을 높이기 위해 설측으로 연장된 견인스크류를 순측의 견고한 안내선과 병행 적용하였다. 발치 직후 미리 제작된 견치 치근 모델을 적용하여 발치와의 깊이를 형성하고 또한 교정용 미니스크류 임플란트를 이용하여 고정원을 보강하였다. 이러한 방법을 적용하여 골격성 II급 관계 및 전치 돌출을 보이는 성인 여환에서 효과적인 견치 및 전치부 견인을 통해 치료기간을 13개월로 단축할 수 있었다. 우려했던 치수의 실활 혹은 치주조직의 병소는 발견되지 않았으며 치료 후 10개월 유지 시에도 양호한 교합관계 및 치주조직의 건강상태를 보였다. 본 증례에서 소개된 방법을 통하여 급속 견인을 필요로 하는 경우에 보다 예측 가능한 방법으로 효율적인 치료를 할 수 있을 것으로 사료된다.

에너지 신사업 플랫폼을 위한 정보보호 방안에 대한 연구

안광석(Kwang-Seok Ahn),김진희(Jin-Hee Kim),문세인(Se-In Moon),전병훈 대한전기학회 2023 대한전기학회 학술대회 논문집 Vol.2023 No.10-3

에너지 신사업 플랫폼에 대한 연구

안광석(Kwang-Seok Ahn),김진희(Jin-Hee Kim),문세인(Se-In Moon),전병훈 대한전기학회 2023 대한전기학회 학술대회 논문집 Vol.2023 No.4