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Pinar Kuru, M.D.,Aylin Cakiroglu, M.I.,Aynur Er, M.S.,Hincal Ozbakir, M.I.,Ali Emin Cinel, M.S.,Busra Cangut, M.S.,Merve Iris, M.S.,Berkay Canbaz, M.S.,Ebru Pıçak, M.S.,Mustafa Yuksel, M.D. 대한흉부외과학회 2016 Journal of Chest Surgery (J Chest Surg) Vol.49 No.1
Background: Pectus excavatum (PE) and pectus carinatum (PC) are the most common chest wall deformities. In this study, we aimed to characterize how patients obtained information about these deformities, as well as patients’ family history, associated medical problems, and postoperative satisfaction after the Nuss and Abramson procedures. Methods: This cross-sectional retrospective study included patients who were operated by a single surgeon between 2006 and 2013. Follow-up calls were made after approval of our institution’s ethics committee. We reached 207 of the 336 PE patients (61.6%) and 73 of the 96 PC patients (76%). Results: The majority of the patients were male (85% of the PE patients and 91.8% of the PC patients). The age of diagnosis of PE was 14.52±0.51 years and the age at the time of operation was 17.89±0.42 years; for PC patients, the corresponding ages were 15.23±0.55 years and 16.77±0.55 years, respectively. A total of 70% of the PE patients and 63.8% of the PC patients obtained information about pectus deformities through the Internet. In 27.1% of the PE patients with an associated anomaly, 57.1% (n=13) had scoliosis, while 41.1% of the PC patients with an associated anomaly had kyphosis (n=5). Postoperative satisfaction, as evaluated on a scale from 0 to 10, was 8.17±0.15 for PE patients and 8.37±0.26 for PC patients. The postoperative pain duration was 51.93±5.18 days for PE patients and 38.5±6.88 days for PC patients. Conclusion: In this study, we found that most patients with pectus deformities were male. The Internet was an important resource for patients to learn about their deformities. Family history and associated anomalies were identified as important aspects for consideration in the clinical setting. The patients reported high levels of postoperative satisfaction, and pain management was found to be one of the most important elements of postoperative care.
Koca, Bulent,Kuru, Bekir,Ozen, Necati,Yoruker, Savas,Bek, Yuksel Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3
Background: To avoid performing axillary lymph node dissection (ALND) for non-sentinel lymph node (SLN)-negative patients with-SLN positive axilla, nomograms for predicting the status have been developed in many centers. We created a new nomogram predicting non-SLN metastasis in SLN-positive patients with invasive breast cancer and evaluated 14 existing breast cancer models in our patient group. Materials and Methods: Two hundred and thirty seven invasive breast cancer patients with SLN metastases who underwent ALND were included in the study. Based on independent predictive factors for non-SLN metastasis identified by logistic regression analysis, we developed a new nomogram. Receiver operating characteristics (ROC) curves for the models were created and the areas under the curves (AUC) were computed. Results: In a multivariate analysis, tumor size, presence of lymphovascular invasion, extranodal extension of SLN, large size of metastatic SLN, the number of negative SLNs, and multifocality were found to be independent predictive factors for non-SLN metastasis. The AUC was found to be 0.87, and calibration was good for the present Ondokuz Mayis nomogram. Among the 14 validated models, the MSKCC, Stanford, Turkish, MD Anderson, MOU (Masaryk), Ljubljana, and DEU models yielded excellent AUC values of > 0.80. Conclusions: We present a new model to predict the likelihood of non-SLN metastasis. Each clinic should determine and use the most suitable nomogram or should create their own nomograms for the prediction of non- SLN metastasis.
Bulent Koca,Bekir Kuru,Savas Yuruker,Barıs Gokgul,Necati Ozen 대한외과학회 2013 Annals of Surgical Treatment and Research(ASRT) Vol.84 No.3
Purpose: The aim of our study is to evaluate the factors affecting surgical margin positivity among patients with invasive ductal breast cancer who underwent breast-conserving surgery (BCS) after preoperative diagnostic core biopsy. Methods: Two hundred sixteen patients with stage I, II invasive ductal breast carcinoma who had histological diagnosis with preoperative tru-cut biopsy and underwent BCS were included in the present study. Potential factors that affect the positive surgical margin were analyzed. In univariate analysis, the comparisons of the factors affecting the surgical margin positivity were made by chi-square test. Logistic regression test was used to detect the independent factors affecting the surgical margin positivity. Results: Positive axillary lymph node (odds ratio [OR], 8.2; 95% confidence interval [CI], 3.01 to 22.12), lymphovascular invasion (LVI; OR, 3.9; 95% CI, 1.62 to 9.24), extensive intraductal component (EIC; OR, 6.1; 95% CI, 2.30 to 16.00), presence of spiculation (OR, 5.1; 95% CI, 2.00 to 13.10) or presence of microcalcification in the mammography (OR, 13.7; 95% CI, 4.04 to 46.71) have been found to be the independent and adverse factors affecting surgical margin positivity. Conclusion: Considering decision making for the extent of the excision and for achieving negative surgical margin before BCS, positive axillary lymph node, LVI, EIC, spiculation or microcalcification in mammography are related as predictor factors for positive surgical margin.
Validity and Reliability of the Turkish Version of the Nuss Questionnaire Modified for Adults
A. Tugba Bahadir,Pinar Kuru,Ceyda Afacan,Nezih Onur Ermerak,Korkut Bostanci,Mustafa Yuksel 대한흉부외과학회 2015 Journal of Chest Surgery (J Chest Surg) Vol.48 No.2
Background: Pectus excavatum (PE) is the most common chest wall deformity. The Nuss Questionnaire modifiedfor Adults (NQmA) is a disease-specific health-related quality of life assessment tool for patients with pectusdeformities. The aim of this study is to adapt the NQmA into Turkish. Methods: Two hundred and sixty-five patientswith PE were participated, with an age range of 14 to 29 years. All patients underwent a physical examinationand had not undergone corrective surgery. The Turkish version of the NQmA was completed by patients andtheir parents. Results: The content validity index based on expert opinions was 91% for the patient questionnaireand 96% for the parent questionnaire. The Cronbach’s alpha value for the NQmA was found to be 0.805 for thepatient questionnaire and 0.800 for the parent questionnaire. Exploratory factor analysis was used to assess constructvalidity. Two factors explained 51.1% of the total variance in the patient questionnaire (psychosocial:31.145%, Cronbach’s alpha=0.818; physical: 19.955%, Cronbach’s alpha=0.862). In the parent questionnaire, two factorsexplained 51.422% of the total variance (psychosocial: 26.097%, Cronbach’s alpha=0.743; physical: 25.325%,Cronbach’s alpha=0.827). Construct validity was confirmed by confirmatory factor analysis. Conclusion: The Turkishversion of the NQmA was found to be valid and reliable for the assessment of quality of life in patients with PE.
Optical Potential Study of Electron Scattering by Rubidium
J. H. Chin,Kuru Ratnavelu,Y. Zhou 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.41
The coupled-channel optical method (CCOM) has been implemented in the study of electron-rubidium scattering. This method includes the continuum effect in the calculation via an ab-initio optical potential. Eight atomic states (5s, 5p, 4d, 6s, 6p, 5d, 7s, 7p) were used together with the continuum optical potential in the 5s-5s, 5s-5p and 5p-5p coupling. The elastic, inelastic and total cross sections for electron-rubidium scattering at low and intermediate energies, ranging from 10eV to 100eV, are reported. The results are compared with available experimental and theoretical data.
Positron Impact Excitation (n = 2 states) of Hydrogen at 20 eV
M. Z. M. Kamali,Kuru Ratnavelu 한국물리학회 2011 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.59 No.41
The calculation of accurate differential cross sections (DCS) has always posed a litmus test for theoretical models. Among the positron-atom scattering systems, positron-hydrogen (e^+-H) atom is the fundamental prototype. Thus, the present work utilizes 12 and 15 states coupled-channel optical method (CCOM) calculations to study the DCS H(2s+2p) excitation together with the angular correlation parameters (λ(2p)) for e^+-H system at 20 eV. But up to now, there have been no measurements yet on the DCS for this system. Comparison is also done with other theoretical and experimental work is presented here with the electron case.
Complications of Completion Versus Total Thyroidectomy
Gulcelik, Mehmet Ali,Kuru, Bekir,Dincer, Halil,Camlibel, Mithat,Yuksel, Ulvi Murat,Yenidogan, Erdinc,Reis, Erhan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Introduction : The objective of this study was to analyze the complication rates after completion thyroidectomy and compare them with primary total benign and malign thyroidectomy causes in total of 647 patients. Patients and Methods: Among 647 patients, there were 159 receiving completion thyroidectomy for differentiated thyroiud cancer (DTC) (Group 1); 217 patients receiving total thyroidectomy for DTC (Group 2) and 271 given total thyroidectomy for benign diseases (Group 3). Results: When groups were compared for complications, there were no significant difference except temporary hypocalcemia between completion thyroidectomy and total thyroidectomy for DTC. When the total thyroidectomies were compared (Group 2 and 3), there were no significant difference observed except unilateral temporary RLN palsy. Conclusion: With improvements in surgical technique and experience, complication rates of thyroidectomy performed for benign or malign diseases are reduced. In spite of the improvement in surgical experience, temporary RLN palsy and hypoparathyroidism are the main complications in completion thyroidectomies which need special attention. To evaluate the patients more carefully in preoperative period and performing adequate thyroidectomy appears more logical.
A Neuroleptic Malignant Syndrome Without Rigidity
İlker Özdemir,Erkan Kuru,Yasir Safak,Rıza Gökçer Tulacı 대한신경정신의학회 2018 PSYCHIATRY INVESTIGATION Vol.15 No.2
Neuroleptic malignant syndrome (NMS) is an uncommon but potentially lethal idiosyncratic reaction which may emerge in the aftermath of the treatments with neuroleptics demonstrating itself with the symptoms of altered consciousness, high fever, impaired autonomic functions, and muscle rigidity. Although various risk factors have been identified for NMS, its etiology is not completely known. The mortality and morbidity related with NMS could be reduced by early diagnosis, interruption of the neuroleptics used within a short period and aggressive treatment. Our case is different from general NMS cases due to lack of rigidity. A NMS case which developed within a short time in the aftermath of multiple antipsychotic use and wherein no rigidity was observed shall be discussed in this case report.