The Feasibility of Establishing Color Imagery Scales for Various Constructional Landscapes

Wen-Guey Kuo,Yu-Pin Li,Yuh-Chang Wei,Chih-Wen Cheng,Wei-Min Fu 한국색채학회 2017 AIC 2017 Jeju Vol.2017 No.10

A methodology of quantifying the environmental color imagery of color images of constructional landscapes individually was created in this study based on the new color imagery scales designed with combining a modified psychophysical method, Magnitude Estimation Method celebrated in the field of color science and the semantic differential method proposed by Osgood. The color imageries of the cumulated constructional landscape-image samples respectively were further estimated under a conditioned room using the creative experimental methodology. Meanwhile, a set of new environmental color imagery scales LEB were derived from the experimental results, and would be expected to raise the feasibility of computerized prediction in color imagery for the practical environment at speed during the field trial in the near future.

The Optimum Dietary Essential Amino Acid Pattern for Male Taiwan Country Chicks

Wei, Hen-Wei,Kuo, Hsin-Mei,Chiu, Wen-Zan,Chen, Bao-Ji Asian Australasian Association of Animal Productio 2009 Animal Bioscience Vol.22 No.8

The objective of this study was to estimate the optimum dietary essential amino acid pattern for male Taiwan country chicks. A series of experiments was conducted with chicks, 14 d of age, for 2 wks. A basal synthetic diet was established using a dose response test for all essential amino acids referring to the broiler requirements recommended by NRC (1994). Twelve chicks were sacrificed at the beginning to provide initial body nitrogen data, and every group of six birds received the basal diet or a diet with a deficiency in a single essential amino acid in twenty one treatments by intubation according to their daily metabolic body weight (MBW). Deposited body nitrogen was determined using comparative slaughtering. According to the daily intake from the limiting amino acid per unit of MBW and the body nitrogen accretion rates for every two deficient groups with the same limiting amino acid but at different levels, a corresponding straight line was computed for each essential amino acid to intersect with a horizontal line made by the body nitrogen accretion rate of the control group. The x coordinate of the intersection represented the daily requirement for growth plus maintenance based on MBW corresponding to the essential amino acid. The amino acid ratios can be considered as the optimum pattern of dietary essential amino acids. The results, expressed with respect to lysine = 100, were arginine 105, methionine 81, histidine 34, tryptophan 18, leucine 103, phenylalanine 135, isoleucine 69, threonine 65 and valine 79. This pattern could be utilized to compute the dietary requirements (g/kg feed) for all essential amino acids by multiplying by the requirement of a single essential amino acid cited from the literature.

Ginsenoside Rg3 ameliorates allergic airway infl ammation and oxidative stress in mice

Wen-Chung Huang,Tse-Hung Huang,Kuo-Wei Yeh,Ya-Ling Chen,Szu-Chuan Shen,Chian-Jiun Liou 고려인삼학회 2021 Journal of Ginseng Research Vol.45 No.6

Background: Ginsenoside Rg3, isolated from Panax ginseng, has anti-inflammatory and anti-tumor activities. It is known to reduce inflammation in acute lung injury in mice, and to reduce the expression ofinflammatory cytokines and COX-2 in human asthmatic airway epithelium. In this study, we attemptedto determine whether ginsenoside Rg3 inhibits airway inflammation, oxidative stress, and airwayhyperresponsiveness (AHR) in the lungs of asthmatic mice. We also investigated its effects on oxidativestress and the inflammatory response in tracheal epithelial cells. Methods: Asthma symptoms were induced in female BALB/c mice sensitized with ovalbumin (OVA). Micewere divided into five groups: normal controls, OVA-induced asthmatic controls, and asthmatic micetreated with ginsenoside Rg3 or prednisolone by intraperitoneal injection. Inflammatory BEAS-2B cells(human tracheal epithelial cells) treated with ginsenoside Rg3 to investigate its effects on inflammatorycytokines and oxidative responses. Results: Ginsenoside Rg3 treatment significantly reduced eosinophil infiltration, oxidative responses,airway inflammation, and AHR in the lungs of asthmatic mice. Ginsenoside Rg3 reduced Th2 cytokineand chemokine levels in bronchoalveolar lavage fluids and lung. Inflammatory BEAS-2B cells treated withginsenoside Rg3 reduced the eotaxin and pro-inflammatory cytokine expressions, and monocyteadherence to BEAS-2B cells was significantly reduced as a result of decreased ICAM-1 expression. Furthermore, ginsenoside Rg3 reduced the expression of reactive oxygen species in inflammatory BEAS-2B cells. Conclusion: Ginsenoside Rg3 is a potential immunomodulator that can ameliorate pathological featuresof asthma by decreasing oxidative stress and inflammation

Effects of Nano-Materials on Properties of Waterworks Sludge Ash Cement Paste

Kuo, Wen-Ten,Lin, Kae-Long,Chang, Wei-Che,Luo, Huan-Lin 한국공업화학회 2006 Journal of Industrial and Engineering Chemistry Vol.12 No.5

The Inventory and Statistics of Potential Large-scale Landslide Areas in Southern Taiwan

( Kuo-wei Li ),( Chien-yu Lin ),( Jyh-jong Liao ),( Yi-wen Pan ),( Keng-hao Kang ),( Che-ming Yang ) 대한지질공학회 2019 대한지질공학회 학술발표회논문집 Vol.2019 No.2

This study produced an inventory of the 2,523 potential large-scale landslide areas (PLSLAs) in southern Taiwan. These PLSLAs were delineated using LiDAR DEM of 1m resolution after the 2009 Typhoon Morakot by other institutes. Using the inventory, we conducted a statistical analysis of the important geologic and geomorphologic factors possibly related to a PLSLA. The statistical analyses reveal that, among the 2,523 PLSLAs, (1) 82% of elevation are between 750 and 2,750 m, (2) 79% of the area are between 10 and 40 hectares, (3) 76% of the slope height are between 200 and 600 m, (4) 86% of the slope are between 25 and 40 degrees and (5) 83 percent of stream order are less than 3. Rock formations of these PLSLAs range from Oligocene to Miocene; 67% of the strata are slate, and 12% are interbedded of sandstone and shale. This study selected 24 medium to high risk cases of the 2,523 PLSLAs, and interpreted the micro-geomorphological features from 1m LiDAR DEM. The following three patterns were present: (1) PLSLA with clear features of gravitational slope deformation in slope height more than 500 m condition, (2) PLSLA with the relic of paleo landslides induced by gravitational buckling, toppling, or plane sliding, (3) PLSLA with river bank erosion on slope toe and head-cut erosion induced by gully development. Based on statistics, the stream order of the PLSLAs with gravitational slope deformation usually would exceed 3; 83% of PLSLAs are the areas also with paleo large-scale landslide.

Development of seven secondary neoplasms in a nevus sebaceous: a case report and literature review

Kuo, Yi-Wen,Lin, Jung-Chia,Tsai, Wei-Hsuan Korean Cleft Palate-Craniofacial Association 2022 Archives of Craniofacial Surgery Vol.23 No.2

Nevus sebaceous of Jadassohn is a congenital cutaneous hamartoma with epidermal, sebaceous, follicular, and apocrine structures that usually appears at birth or in early childhood. It has the potential to generate a variety of secondary neoplasms of different lineages, and the risk increases with patient age. Although multiple neoplasms may occasionally arise within the same lesion, the coexistence of more than five secondary tumors is extremely rare. Here we report a case of seven secondary tumors including syringocystadenoma papilliferum, desmoplastic trichilemmoma, sebaceoma, trichoblastoma, pigmented trichoblastoma, sebaceous adenoma, and tumor of follicular infundibulum arising within a nevus sebaceous. The complete diagnosis relies on the histopathological analysis of multipoint biopsies and delicate pathological sections.

Local Structure Distortion in LiCu₂O₂ Single Crystal at Low Temperature

Tzu-Wen Huang,Kuo-Wei Yeh,Kuan-Li Yu,Yen-Fa Liao,Maw-Kuen Wu 한국자기학회 2008 한국자기학회 학술연구발표회 논문개요집 Vol.- No.-

Controlled Release of Clenbuterol from a Hydroxyapatite Carrier for the Treatment of Alzheimer’s Disease

Yi-Wen Lin,Chih-Hsiang Fang,Ya-Jyun Liang,Ching-Yun Yang,Wei-Ting Kuo,Feng-Huei Lin 한국생체재료학회 2023 생체재료학회지 Vol.27 No.00

Background Alzheimer’s disease is a neurodegenerative disorder, and Aβ aggregation is considered to be the central process implicated in its pathogenesis. Current treatments are faced by challenges such as serious side effects and reduced drug bioavailability. In this study, we developed a drug delivery system for intramuscular injection that uses cellular activity to achieve constant and long-term drug release. Methods Synthesized mesoporous hydroxyapatite (SHAP) was prepared via co-precipitation, and hydrophobic surface modification using stearic acid was then used to load clenbuterol by physical absorption, thus creating the drug delivery system. Clenbuterol release was achieved through cellular activity, with macrophage uptake triggering lysosome/endosome disruption, cytoplasmic release, extracellular exocytosis, and subsequent systemic circulation. Results We found that clenbuterol-loaded SHAP enabled sustained release for more than 2 weeks and effectively modulated inflammation, reduced Aβ oligomer-induced toxicity, and prevented Aβ aggregation. Conclusions Our findings suggest that treatment with clenbuterol loaded in this SHAP delivery system could be a promising strategy for treating Alzheimer’s disease.

Psoas Abscess Caused by Non-Typhoid Salmonella in a Patient with Severe Aplastic Anemia

Chin-Chi Kuo,Shih-Chi Ku,Jann-Tay Wang,Ching-Wei Tsai,Vin-Cent Wu,Wen-Chien Chou 연세대학교의과대학 2010 Yonsei medical journal Vol.51 No.3

The clinical spectrum of infections caused by non-typhoid Salmonella spp. includes gastroenteritis, enteric fever,bacteremia, and extraintestinal localized complications, especially in immunocompromised hosts. Here we report a patient with severe aplastic anemia developing left iliopsoas abscess caused by non-typhoid Salmonella (NTS),which was successfully treated by prolonged antibiotic treatment and repeated debridement. Our data indicate that aplastic anemia is a risk factor for infection caused by NTS.

Clinicopathological Significance of Reduced SPARCL1 Expression in Human Breast Cancer

Cao, Fang,Wang, Kuo,Zhu, Rong,Hu, Yong-Wei,Fang, Wen-Zheng,Ding, Hou-Zhong Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Secreted protein acidic and rich in cysteines-like protein 1 (SPARCL1), an extracellular matrix glycoprotein, has been implicated in the pathogenesis of several disorders including cancer. However, little is known about the expression and significance of SPARCL1 in human breast cancer. The aim of this study was to determine the expression pattern and clinicopathological significance of SPARCL1 in a Chinese breast cancer cohort. mRNA and protein expression of SPARCL1 in human breast cancer cell lines and breast cancer tissues was detected using the reverse transcription-polymerase chain reaction, real-time quantitative PCR, and Western blotting, respectively. Immunostaining of SPARCL1 in 282 Chinese breast cancer samples was examined and associations with clinicopathological parameters were analyzed. Compared to the positive expression in immortalized human breast epithelial cells, SPARCL1 was nearly absent in human breast cancer cell lines. Similarly, a significantly reduced expression of SPARCL1 was observed in human breast cancer tissues compared to that in normal breast epithelial tissues, for both mRNA and protein levels (P < 0.001). Immunohistochemical analysis showed that strong cytoplasmic immunostaining of SPARCL1 was observed in almost all normal breast samples (43/45) while moderate and strong immunostaining of SPARCL1 was only detected in 191 of 282 (67.7%) breast cancer cases. Moreover, down-regulation of SPARCL1 was significantly correlated with lymphatic metastasis (P = 0.020) and poor grade (P = 0.044). In conclusion, SPARCL1 may be involved in the breast tumorigenesis and serve as a promising target for therapy of breast cancer.