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      • SCIESCOPUSKCI등재

        Photonic Generation of Frequency-tripling Vector Signal Based on Balanced Detection without Precoding or Optical Filter

        Kun Qu,Shanghong Zhao,Xuan Li,Zihang Zhu,Qinggui Tan 한국광학회 2018 Current Optics and Photonics Vol.2 No.2

        A novel approach for frequency-tripling vector signal generation via balanced detection without precoding and optical filter is proposed. The scheme is mainly utilizing an integrated dual-polarization quadrature phase shift keying (DPQPSK) modulator. In the DPQPSK modulator, one QPSK modulator is driven by an RF signal to generate high-order optical sidebands, while the other QPSK modulator is modulated by I/Q data streams to produce baseband vector signal as an optical carrier. After that, a frequency-tripling 16-quadrature-amplitude-modulation (16QAM) vector millimeter-wave (mm-wave) signal can be obtained by balanced detection. The proposed scheme can reduce the complexity of transmitter digital signal processing. The results show that, a 4 Gbaud baseband 16QAM vector signal can be generated at 30 GHz by frequency-tripling. After 10 km single-mode fiber (SMF) transmission, the constellation and eye diagrams of the generated vector signal perform well and a bit-error-rate (BER) below than 1e-3 can be achieved.

      • KCI등재

        上海自??多元??解?机制前瞻

        구곤 ( Qu Kun ) 한국법정책학회 2014 법과 정책연구 Vol.14 No.3

        On the basis of elaborating the basic establishment situation about the Shanghai Pilot Free Trade Zone and Its legal nature in narrow sense. This paper points out that Shanghai Pilot Free Trade Zone is different from the previous reform and opening policies which are characterized by preferential treatment. Shanghai Pilot Free Trade Zone turned to create kinds of policies innovation. The paper will focus on construction and innovation of dispute settlement mechanism in Shanghai Pilot Free Trade Zone, feature of dispute settlement mechanism is geared to international standards as much as possible under the current judicial system. The paper analyzes the main factors affecting the dispute of Shanghai Pilot Free Trade Zone and Its possible types of disputes, proposes that we should establish Shanghai Pilot Free Trade Zone Multiple Dispute Resolution Mechanism, aims at coping with the sharp increase of all kinds of disputes happened in Shanghai Pilot Free Trade Zone, and reducing Its trial pressure. According to the situation of disputes since the establishment of the Shanghai Pilot Free Trade Zone, this paper analyzes the requirement of Shanghai Pilot Free Trade Zone about the dispute resolution mechanism. The paper draw a conclusion: Multiple dispute resolution mechanism in Shanghai Pilot Free Trade Zone should be according to Its features towards to provide legal protection and legal services, this protection and services shall be constantly adjust and perfect with the development of Shanghai Pilot Free Trade Zone. The concrete frame of multiple dispute resolution mechanism in Shanghai Pilot Free Trade Zone include court and the lawsuit procuratorate agencies procuratorial mechanism, commercial disputes arbitration system, Shanghai Pilot Free Trade Zone commercial joint tribunal and Shanghai culture creative industry mechanism of intellectual property legal services platform mediation center system, Shanghai Pilot Free Trade Zone industry association dispute resolution mechanism and multiple dispute resolution mechanism about supporting mechanism in Shanghai Pilot Free Trade Zone.

      • KCI등재

        Modeling, analysis and optimization of adsorption parameters of Au(III) using low-cost agricultural residuals buckwheat hulls

        Kun Deng,Ping Yin,Xiguang Liu,Qinghua Tang,Rongjun Qu 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

        The agricultural residuals buckwheat hulls in the region of Jiaodong, China (BHJC) were employed to adsorb Au(III) ions both in the spiked samples and the gold-plating wastewater samples, and the relevant adsorption kinetics and isotherms were investigated. The investigation on the adsorption selectivity showed that BHJC displayed strong affinity for gold in the aqueous solutions. Furthermore, the process optimization was performed using response surface methodology (RSM), the quantitative relationship between the gold uptake and the different levels of experimental factors was used to work out optimized levels of these parameters.

      • SCOPUSKCI등재

        A Neuro-Fuzzy Pedestrian Detection Method Using Convolutional Multiblock HOG

        Kun-Woo Myung(명근우),Le-Tao Qu(곡락도),Joon-Shik Lim(임준식) 대한전기학회 2017 전기학회논문지 Vol.66 No.7

        Pedestrian detection is a very important and valuable part of artificial intelligence and computer vision. It can be used in various areas for example automatic drive, video analysis and others. Many works have been done for the pedestrian detection. The accuracy of pedestrian detection on multiple pedestrian image has reached high level. It is not easily get more progress now. This paper proposes a new structure based on the idea of HOG and convolutional filters to do the pedestrian detection in single pedestrian image. It can be a method to increase the accuracy depend on the high accuracy in single pedestrian detection. In this paper, we use Multiblock HOG and magnitude of the pixel as the feature and use convolutional filter to do the to extract the feature. And then use NEWFM to be the classifier for training and testing. We use single pedestrian image of the INRIA data set as the data set. The result shows that the Convolutional Multiblock HOG we proposed get better performance which is 0.015 miss rate at 10-4 false positive than the other detection methods for example HOGLBP which is 0.03 miss rate and ChnFtrs which is 0.075 miss rate.

      • KCI등재
      • Adverse Effects of Preserved Vegetables on Squamous Cell Carcinoma of Esophagus and Precancer Lesions in a High Risk Area

        Song, Qing-Kun,Zhao, Lin,Li, Jun,He, Yu-Ming,Jiang, Cui-Ping,Jiang, Hai-Dong,Qu, Chen-Xu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Introduction: Squamous cell carcinoma of esophagus (ESCC) is one of the most common cancers in China. Preserved vegetables are processed foods and consumed in high amounts in the high risk areas for ESCC. This study aimed to investigate the relationships of preserved vegetable consumption with ESCC and precancer lesions. Methods: Cases from Yanting cancer hospital with pathological diagnosis of primary cancer, along with controls and individuals diagnosed with precancer lesions by endoscopy with iodine staining were interviewed. Trained staff collected data on dietary habits 1 year before the interview. An unconditional logistic regression model was used to estimate odds ratios of preserved vegetable consumption for precancer lesions and cancer. Results: Adjusting for potential confounders, intake of preserved vegetables (OR=2.92, 95%CI 1.32~6.47) and longer intake period (OR=5.78, 95%CI 2.26~14.80) were associated with higher risk of ESCC. Compared with lowest intake frequency, the highest was associated with a 3.0-fold risk for precancer lesions and 3.59-fold risk for ESCC (both p<0.05). Conclusion: Consumption of preserved vegetables is a risk factor for esophageal lesions in high risk areas. The carcinogenicity of preserved vegetables needs investigation in further studies and the public health strategies for reducing the consumption might be initiated in high risk areas.

      • KCI등재

        Nurses' Colleague Solidarity and Job Performance: Mediating Effect of Positive Emotion and Turnover Intention

        Wang Jizhe,Liu Shao,Qu Xiaoyan,He Xingrong,Zhang Laixiang,Guo Kun,Zhu Xiuli 한국산업안전보건공단 산업안전보건연구원 2023 Safety and health at work Vol.14 No.3

        Background: Job performance is known as an essential reflection of nursing quality. Colleague solidarity, positive emotion, and turnover intention play effective roles in a clinical working environment, but their impacts on job performance are unclear. Investigating the association between nurses’ colleague solidarity and job performance may be valuable, both directly and through the mediating roles of positive emotion and turnover intention. Methods: In this cross-sectional study, a total of 324 Chinese nurses were recruited by convenience sampling method from July 2016 to January 2017. Descriptive analysis, Spearman’s correlation analysis, and the structural equation model were applied for analysis by SPSS 26.0 and AMOS 24.0. Results: A total of 49.69% of participants were under 30 years old, and 90.12% of participants were female. Colleague solidarity and positive emotion were positively connected with job performance. The results indicated the mediating effects of positive emotion and turnover intention in this relationship, respectively, as well as the chain mediating effect of positive emotion and turnover intention. Conclusions: In conclusion, dynamic and multiple supportive strategies are needed for nurse managers to ameliorate nursing job performance by improving colleague solidarity and positive emotion and decreasing turnover intention based on the job demand-resource model.

      • Association between Dietary Behavior and Esophageal Squamous Cell Carcinoma in Yanting

        Zhao, Lin,Liu, Chun-Ling,Song, Qing-Kun,Deng, Ying-Mei,Qu, Chen-Xu,Li, Jun Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.20

        Background: Yanting is one of high risk areas for esophageal cancer and the screening program was therefore initiated there. This study was aimed to investigate the dietary behaviors on the risk of esophageal squamous cell carcinoma (ESCC), among the individuals with normal and abnormal esophagus mucosa. Materials and Methods: A frequency matched case-controls study was proposed to estimate the different distribution of dietary behavior between individuals of control, esophagitis and cancer groups. Cancer cases were selected from hospitals. Esophagitis cases and controls were selected from screening population for ESCC. Health workers collected data for 1 year prior to interview, in terms of length of finishing a meal, temperature of eaten food and interval between water boiling and drinking. Chi-square, Kruskal-Wallis tests and unconditional logistic regression model were used to estimate differences and associations between groups. Results: Compared with controls, length of finishing a meal ${\geq}15mins$ was related to a reduced OR for cancer (OR=0.46, 95%CI, 0.22-0.97) and even compared with cases of esophagitis, the OR of cancer was reduced to 0.30 (95%CI, 0.13-0.72). The OR for often eating food at a high temperature was 2.48 (95%CI 1.06, 5.82) for ESCC as compared with controls. Interval between water boiling and drinking of ${\geq}10mins$ was associated with lower risk of cancer: the OR was 0.18 compared with controls and 0.49 with esophagitis cases (p<0.05). Conclusions: Length of eating food ${\geq}15mins$ and interval between water boiling and drinking ${\geq}10mins$ are potentially related to reduced risk of esophageal SCC, compared with individuals with normal and abnormal esophageal mucosa. Recommendations to Yanting residents to change their dietary behaviors should be made in order to reduce cancer risk.

      • KCI등재

        Resveratrol Exerts Dosage-Dependent Effects on the Self-Renewal and Neural Differentiation of hUC-MSCs

        Wang, Xinxin,Ma, Shanshan,Meng, Nan,Yao, Ning,Zhang, Kun,Li, Qinghua,Zhang, Yanting,Xing, Qu,Han, Kang,Song, Jishi,Yang, Bo,Guan, Fangxia Korean Society for Molecular and Cellular Biology 2016 Molecules and cells Vol.39 No.5

        Resveratrol (RES) plays a critical role in the fate of cells and longevity of animals via activation of the sirtuins1 (SIRT1) gene. In the present study, we intend to investigate whether RES could promote the self-renewal and neural-lineage differentiation in human umbilical cord derived MSCs (hUC-MSCs) in vitro at concentrations ranging from 0.1 to $10{\mu}M$, and whether it exerts the effects by modulating the SIRT1 signaling. Herein, we demonstrated that RES at the concentrations of 0.1, 1 and $2.5{\mu}M$ could promote cell viability and proliferation, mitigate senescence and induce expression of SIRT1 and Proliferating Cell Nuclear Antigen (PCNA) while inhibit the expression of p53 and p16. However, the effects were reversed by 5 and $10{\mu}M$ of RES. Furthermore, RES could promote neural differentiation in a dose-dependent manner as evidenced by morphological changes and expression of neural markers (Nestin, ${\beta}III-tubulin$ and NSE), as well as pro-neural transcription factors Neurogenin (Ngn)1, Ngn2 and Mash1. Taken together, RES exerts a dosage-dependent effect on the self-renewal and neural differentiation of hUC-MSCs via SIRT1 signaling. The current study provides a new strategy to regulate the fate of hUC-MSCs and suggests a more favorable in vitro cell culture conditions for hUCMSCs-based therapies for some intractable neurological disorders.

      • KCI등재

        Lactate exacerbates lung damage induced by nanomicroplastic through the gut microbiota–HIF1a/PTBP1 pathway

        Xuan Lihui,Xu Zheng,Luo Jinhua,Yin Wang,Yan Yuhui,Qu Can,Xie Zuozhong,Skonieczna Magdalena,Zhou Ping-Kun,Huang Ruixue 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Exposure to nanomicroplastics (nano-MPs) can induce lung damage. The gut microbiota is a critical modulator of the gut–lung axis. However, the mechanisms underlying these interactions have not been elucidated. This study explored the role of lactate, a key metabolite of the microbiota, in the development of lung damage induced by nano-MPs (LDMP). After 28 days of exposure to nano-MPs (50–100 nm), mice mainly exhibited damage to the lungs and intestinal mucosa and dysbiosis of the gut microbiota. Lactate accumulation was observed in the lungs, intestines and serum and was strongly associated with the imbalance in lactic acid bacteria in the gut. Furthermore, no lactate accumulation was observed in germ-free mice, while the depletion of the gut microbiota using a cocktail of antibiotics produced similar results, suggesting that lactate accumulation in the lungs may have been due to changes in the gut microbiota components. Mechanistically, elevated lactate triggers activation of the HIF1a/PTBP1 pathway, exacerbating nano-MP-induced lung damage through modulation of the epithelial–mesenchymal transition (EMT). Conversely, mice with conditional knockout of Ptbp1 in the lungs (Ptbp1flfl) and PTBP1-knockout (PTBP1-KO) human bronchial epithelial (HBE) cells showed reversal of the effects of lactate through modulation of the HIF1a/PTBP1 signaling pathway. These findings indicate that lactate is a potential target for preventing and treating LDMP.

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