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- 저자 : Kuang Gu (검색결과 4 건)
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Impact of Size on Humidity Sensing Property of Copper Oxide Nanoparticles
Yang Gu,Huina Jiang,Zi Ye,Ning Sun,Xuliang Kuang,Weijing Liu,Gaofang Li,Xiaojun Song,Lei Zhang,Wei Bai,Xiaodong Tang 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.1
Three sizes of CuO nanosheets were synthesized by hydrothermal method. The structure and morphology of CuO nanosheets were characterized by X-ray difraction and scanning electron microscopy. Dielectrophoresis nano-manipulation technique was employed to arrange the materials on pre-designed Ti/Au electrodes to fabricate the three humidity sensors, and the sensing properties were then tested. The experimental results show that the sensitivity greatly increases with the decreasing size of CuO nanosheets, the sensitivity of sensor a, b, c are 369%, 3278%, 22,611% in 97.3% RH, respectively. The smaller sized CuO nanomaterials have better response characteristic, the response time of sensor a, b, c under 11.3–97.3% RH are 53 s, 49 s, 32 s, respectively. And correspondingly, hysteresis properties and the repeatability are also a little infuenced. In addition, based on complex impedance spectroscopy and multilayer adsorption theory, the impact of size on humidity sensing property was discussed. The results indicated the feasibility to obtain higher performance of humidity sensor, especially the higher sensitivity, via employment the smaller size sensing nanomaterials.
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AGENT: an adaptive grouping and entrapping method for flocking systems
Wang Chen,Kuang Wenxi,Gu Minqiang,Fan Zhun 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.1
This study proposes a distributed algorithm that enables agents’ adaptive grouping and entrapment of multiple targets via automatic decision making, smooth flocking, and well-distributed entrapping. In this study, an agent distributed decision framework is proposed. Agents make their own decisions about which targets to surround based on environmental information. Meanwhile, a modified Vicsek model is proposed to enable agents to smoothly change formations to adapt to the environment, while forming an entrapping effect on the target. In addition, we provide an optional rotary entrapping function for this model to achieve better effect. We validate the performance of proposed method using simulation and physical experiments.
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Yong Zhou,Kuang Gu,Fengying Sun,Shoumei Xuan,Duohong Zou,Jiacai He,Xuyan Tang 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.4
BACKGROUND: Regenerative medicine by using stem cells from dental pulp is promising for treating patients with critical limb ischemic (CLI). Here, we investigated the difference in the angiogenetic ability of stem cells from human exfoliated deciduous teeth (SHED) and human dental pulp stem cells (DPSC). METHODS: SHED and DPSC were harvested from dental pulp and analyzed in flow- cytometry for detecting the expression of surface markers. Levels of angiogenetic marker were examined by RT-PCR and Western-blot. Eighteen immunodeficient mice of critical limb ischemic model were divided into three groups: SHED, DPSC and saline, which was administered with SHED, DPSC or saline intramuscularly. Histological examination was performed to detect the regenerative results. RESULTS: A highly expression of CD146 was detected in SHED. Moreover, cells with negative expression of both CD146 and CD31inSHEDwere more in comparison with those inDPSC. Expression of angiogenesis factors includingCXCL12,CXCR4,Hif- 1a, CD31, VEGF and bFGFwere significant higher in SHED thanDPSC by the RT-PCR and Western-Blot results. SHED induced more CD31 expression and less fibrous tissue formation in the critical limb ischemic model as compare with DPSC and saline. CONCLUSION: Both SHED and DPSC possessed the ability of repairing CLI. With expressing more proangiogenesis factors, SHED may have the advantage of repairing CLI.
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Effects of Androgen Receptor Overexpression on Chondrogenic Ability of Rabbit Articular Chondrocytes
Hui Liu,Shoumei Xuan,Zhoujing Zhang,Kuang Gu,Duohong Zou,Jiacai He,Yong Zhou 한국조직공학과 재생의학회 2021 조직공학과 재생의학 Vol.18 No.4
Background: The role of sex hormones and their receptors has drawn much attention in the process of cartilage regeneration. This study aimed to investigate the effect of androgen receptor (AR) on the chondrogenic ability of articular chondrocytes and the related mechanism. Methods: Articular chondrocytes were isolated, cultured, identified by toluidine blue staining and then transduced with lentivirus carrying the AR gene. The cell viability was determined using Cell Counting Kit-8, and cell apoptosis was assessed by flow cytometry analysis. The effects of AR overexpression on the expression of cartilage-specific proteins and some signalling molecules were evaluated by real-time PCR and Western blotting. Using 24 New Zealand rabbits, the regeneration of rabbit articular cartilage defects was further investigated in vivo and evaluated histologically. Results: The overexpression of AR significantly reduced the apoptosis rate of chondrocytes but did not affect their proliferation. The overexpression of AR also promoted the expression of Sry-related HMG box 9, collagen II and aggrecan, decreased the expression of matrix metalloproteinase-13, and downregulated p-S6 and RICTOR. The experimental group with AR-overexpressing chondrocytes exhibited superior regeneration of cartilage defects. Conclusion: AR overexpression can maintain the phenotype of chondrocytes and promote chondrogenesis in vitro and in vivo. mTOR-related signalling was inhibited. Background: The role of sex hormones and their receptors has drawn much attention in the process of cartilage regeneration. This study aimed to investigate the effect of androgen receptor (AR) on the chondrogenic ability of articular chondrocytes and the related mechanism. Methods: Articular chondrocytes were isolated, cultured, identified by toluidine blue staining and then transduced with lentivirus carrying the AR gene. The cell viability was determined using Cell Counting Kit-8, and cell apoptosis was assessed by flow cytometry analysis. The effects of AR overexpression on the expression of cartilage-specific proteins and some signalling molecules were evaluated by real-time PCR and Western blotting. Using 24 New Zealand rabbits, the regeneration of rabbit articular cartilage defects was further investigated in vivo and evaluated histologically. Results: The overexpression of AR significantly reduced the apoptosis rate of chondrocytes but did not affect their proliferation. The overexpression of AR also promoted the expression of Sry-related HMG box 9, collagen II and aggrecan, decreased the expression of matrix metalloproteinase-13, and downregulated p-S6 and RICTOR. The experimental group with AR-overexpressing chondrocytes exhibited superior regeneration of cartilage defects. Conclusion: AR overexpression can maintain the phenotype of chondrocytes and promote chondrogenesis in vitro and in vivo. mTOR-related signalling was inhibited.
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