牙山湖에서 大湖湖 沿岸의 淡水湖 連結에 의한 效率的인 水資源 利用方案

구본수,최한규,이성홍 江原大學校 産業技術硏究所 1998 産業技術硏究 Vol.18 No.-

The Asan Bay area Korea is situated in an unbalance or water supply and demand relating to the Ansung, Sapkyo, Dangjin and Youmwha rivers and their estuary reservoirs. The multi-reservoir operation was studied by the Hierarchical Operation Model for Multi-reservoir System(HOMMS) assuming that these four estuary reservoirs were linked to each other in order. The result of this study shows that storage capacity deficiency in 2011 was estimated as 8 MCM in the Sapkyo and 31 MCMin Dae Ho estuary reservoir, respectively. In case of linking four reservoirs, the water deficiency will not occurs in all the reservoirs even if additional agricultural water of 78 MCM/yr was supplied. Total additional water demand for agricultural, municipal and industrial uses was estimated as 321.9 MCM /yr while additional supply by linking the reservoirs was estimated as 160.4 MCM/yr, 50% of additional demand. The remaining 161.5 MCM/yr would be supplied transferring other watershed.

보리 춘파재배 적응성 품종의 특성 및 선발

이춘우,구본철,백성범,손영구,김홍식 한국국제농업개발학회 2002 韓國國際農業開發學會誌 Vol.14 No.1

보리 품종 중 춘파에 적응하는 품종을 선발하기 위하여 올보리 등 16품종을 시험한 결과를 요약하면 다음과 같다. 가. 천립중과 설립량과는 상관관계가 있어 천립중이 무거울수록 10a당 설립이 적고 수량은 많아지는 경향이었다. 춘파 재배는 생육기간이 짧고 고온하에 등숙이 이루어지므로 천립중이 가벼워지는데 대립종이 소립중에 비하여 설립이 적었다. 나. 수량은 맥종간에는 쌀보리가 겉보리나 맥주보리에 비하여 적었고, 또한 년차나 품종간 변이도 컸다. 다. 쌀보리 품종들은 겉보리에 비하여 간장이 짧고, 설립이 많아 수량이 적었다. 라. 춘파재배용으로는 천립중, 설립량, 간장, 성숙기, 수량 등을 고려할 때 올보리와 사천6호가 가장 안정성이 있는 품종으로 판단되었다. This study was conducted to select varieties for spring sowing in barley. The accumulated and the average temperatures affected the 1,000-grain weight and unmatured grain yield. There was a negative correlation between 1,000-grain weight and the yield of unmatured grain. The 1,000-grain weight became lighter because of short growth period and maturing in high temperature under spring sowing condition. Compare with the covered and two-row barley, the grain was lower than naked barley. Among 16 barley varieties. "Olbori", "Sacheon6" were well adapted to spring sowing condition.

三黃瀉心湯이 自發性高血壓 흰쥐의 血壓 및 血淸에 미치는 影響

李星斗,具本泓 慶熙大學校 1983 論文集 Vol.12 No.-

In order to study the effectiveness of Samhwangsasimtang on the Blood Pressure and Serum, the amount of total cholesterol, phospholipid and triglyceride in Serum and Blood Pressure of Spontaneously hypertensive rats were measured. The results were obtained as follows: 1. The Blood Pressure of S.H.R. were significantly lowered than the control group; in the case of sample B group, the effectiveness was recognized from three to four hours after administration, and of sample D group, proved effective around four hours. 2. The effects of administrative medicines on the amount of S-total cholesterol were significant in sample B·D groups, and in sample B group, recognized more effective than sample D group. 3. The effects of administrative medicines on the amount of S-phospholipid were decline to lower in sample B·D groups, but not effective. 4. The effects of administrative medicines on the amount S-triglyceride were recognized in

高血壓性 腦卒中(中風)에 對한 東西醫學的 疫學硏究

鄭在赫,具本泓,張仁圭,崔栖瀅,柳洞俊 WHO COLLABORATING CENTRE FOR TRADITIONAL MEDICINE 1983 東西醫學硏究所 論文集 Vol.2 No.1

Epidemiological studies were done on the 162 hypertensive cerebrovascular accidents cases admitted in the affiliated Oriental Medicine School Hospital Kyung Hee University in 1983 and the following results were obtained. 1. The male to female ratio of the patients was 1.3:1 and the age distribution frequency was as follows; fifties, forties, seventies and thirties(Table 2.) 2. In the C.V.A., there were 119 cases of cerebral thrombosis(73.5%) and 45 cases of intracerebral hemorrhage(26.5%). The ratio was 2.8:1. In the former the male to female ratio was 1.3:1, in the latter it was 1.2:1(Table 3). 3. There were considerable numbers of recurrent cases as shown in Table 4. The first attack was noted in 125 cases(77.2%), the 2nd attack 30 cases(18.5%), the 3rd attack 6 cases(3.1%) , 4th attack 1 case(0.6%). The male to female ratio was as follows. In the first attack it was 1.3:1, in the 2nd attack 1.1:1, the 3rd attack 5.0:1, the 4th attack was noted only in one male case. 4. The occupational frequency order was as follows(Table 5). Unemployed initiated with 45 cases(27.8%), home care 21 cases, Unspecified 19 cases, office worker, business men, farmers and public official etc. 5. The regional distribution was as follows(Table 6). Seoul city led with 102 cases (63.0%) then it was followed by Kyung-Gi, Chung-Cheong, Kyung-Sang, Kang-Won and Jon-Ra province. 6. The systolic pressures at admission were disclosed as follows(Table 7). There were 42 cases(male 20 cases-12.3%, female 22 cases-13.6%) of systolic hypertensive over the WHO standard of 160mmHg, the mean value of systolic pressure was 145mmHg. The diastolic pressures at admission were shown as follows(Table 8). There were 92 cases(56.8%)(male 48 cases-29.6%, female 44 cases-27.2%) of diastolic hypertension over the WHO standard of 95mmHg, the mean value of diastolic pressure was 98mmHg. 7. The patient's favors to salty food, animal fatty food, cigarettes and alcoholic beverage were examined(Table 9). Salty foods were favored by 78 cases(48.2%), animal fatty foods by 78 cases(48.2%), cigarettes by 64 cases(39.5%) and alcohol imbibers were noted in 77 cases(47.5) as shown in table 9. 8. The family history of C.V.A and hypertension was studied (Table 10). In C.V.A there were 28 cases(17.3%) with parental history, 12 cases(7.4%) with siblings history and 7 cases(4.3%) with other relatives, and in hypertension there appeared 14 cases(8.6%) with parental history, 9 cases(5.6%) with sibling history and 6 cases(3.7%) with other relatives. 9. In the past history, hypertension led with 124 cases(76.5%), then C.V.A 37 cases(22.9%) and diabetes mellitus 33 cases(20.4%)(Table 11). 10. In treatment the frequently used herbal recipes were Gamichungshimtang(加味淸心湯), Bosimgunbitang(補心健脾湯), Kyuntongdodamtang(腱痛導痰湯) in 15% of the cerebral hemorrhage cases, respectively, Gamichungshimtang(加味淸心湯) in 20%, Yangkyeuksan(凉膈散), Chowisungchongtang(調胃升淸湯), Yukmichihwangtang(六味地黃湯) in 6%, respectively, in cerebral thrombosis. The most frequently used acupuncture points in C.V.A were shown in Table 12. Taechung(太衡) , Habgok(合谷), Joksamri(足三里), Oekwan(外關), Chungjue(中渚), Jokimeub(足姙泣), Kokji(曲池), Taebak(太白) were frequency order used in C.V.A of both cerebral thrombosis and hemorrhage. 11. In admitted C.V.A patient care, it was stressed that the Oriental Medical Hospital plays important roles and, accordingly, the propriety of East-West medical cooperation was addressed. 12. Through classified disease distribution of admitted patients in the Oriental Medicine Hospital the epidemiological epitome of cerebrovascular accidents and other diseases was presented.

山査子의 效能에 關한 硏究

韓圭彦,具本泓 慶熙大學校 1985 論文集 Vol.14 No.-

In order to study on the effects of Crataegi Fructus(Crataegus pinnatifida Bunge var. major N.E. Br), I obtained the following conclusion as a result of the experiments used animals on the action in G - I tract and uterus. 1. Crataegi Fructus suppressed the spontanceous motility of isolated mice - lieum, and showed ileums of mice and guineapigs direct relaxation of intestinal smooth muscle. 2, Crataegi Fructus suppressed the spontaneous motility of rat-intestine, and inhibited the contractions induced by acetylcholine chloride and BaCl_2 in proportion to the concentration by the pretreatment of the sample. 3. Crataegi Fructus suppressed the contractile motility of isolated rat-uterus, and had anti-oxytocin and anti-prostaglanding actions. 4. Crataegi Fructus suppressed the motility of the small intestine in rabbits. 5. Crataegi Fructus accelerated the transport ratio in the small intestine of mice, and inhibited the stimulent peristalsis induced by FeSO_4 in the small intestine of mice. 6. Crataegi Fructus had the anticathartic action of mice induced by castor oil. 7. Crataegi Fructus showed the inhibitory effects of gastric secretion. By reviewing the above result, it seems that there are thing that have antagonistic interactions in Crataegi Fructus, and I understood that the experimental result were consistent with the effects, namely, digesting the amassed food, digesting the chronic indigestion, circulation the stayed air based on the oriental medical references. In recognition of being applied to gastrointestinal diseases, it is suggested that continuous studies on the heart system in future being applied to are also needed.

高血壓性 腦卒中(中風)에 對한 東西醫學的 疫學硏究

鄭在赫,具本泓,張仁圭,崔栖영,柳東俊 中央醫學社 1983 中央醫學 Vol.45 No.3

Epidemiological studies were done on the 162 hypertensive cerebrovascular accid-ents cases admitted in the affiliated Oriental Medicine School Hospital Kyung Hee University in 1983 and the following results were obtained. 1. The male to female ratio of the patients was 1. 3 : 1 and the age distribution frequency was as follows; fifties, forties, seventies and thirties(Table 2). 2. In the C.T.A., there were 119 cases of cerebral thrombosis(73.5%) and 45 cases of intracerebral hemorrhage (26.5%). The ratio was 2.8 : 1. In the former the male to female ratio was 1.3 : 1, in the latter it was 1.2 : 1(Table 3). 3. There were considerable numbers of recurrent cases as shown in Table 4. The first attack was noted in 125 cases(77.2%), the 2nd attack 30 cases(18.5%), the 3rd attack 6 cases(3.1%), 4th attack 1 case(0.6%). The male to female ratio was as follows. In the first attack it was 1. 3 : 1, in the 2nd attack 1.1 : 1, the 3rd attack 5.0: 1, the 4th attack was noted only in one male case. 4. The occupational frequency order was as follows(Table 5). Unemployed initi-ated with 45 cases(27.8%), home care 21 cases, Unspecified 19 cases, office worker, business men, farmers and public official etc. 5. The regional distribution was as follows(Table 6). Seoul city led with 102 cases (63. 0%) then it was followed by Kyung-Gi, Chung-Cheong, Kyung-Sang, Kang-Won and Jon-Ra province. 6. The systolic pressures at admission were disclosed as follows(Table 7). There were 42 cases(male 20 cases-12.3%, female 22 cases-13.6%) of systolic hypertens-ive over the WHO standard of 160mmHg, the mean value of systolic pressure was 145mmHg. The diastolic pressures at admission were shown as follows(Table 8). There were 92 cases(56.8 %) (male 48 cases-29.6%' female 44 cases-27.2%) of diastolic hypertension over the WHO standard of 95mmHg, the mean value of diastolic pressure was 98mmHg. 7. The patient's favors to salty food, animal fatty food, cigarettes and alcoholic beverage were examined (Table 9). Salty' foods were favored by 78 cases(48.2%), animal fatty foods by 78 cases(48.2%), cigarettes by 64 cases(39.5%) and alcohol imbibers were noted in 77 cases(47.5%) as shown in table 9. 8. The family history of C. V.A and hypertension was studied (Table 10). In C. V.A there were 28 cases (17.3%) with parental history, 12 cases (7.4%) with siblings history and 7 cases (4.3%) with other relatives, and in hypertension there appeared 14 cases(8.6%) with parental history, 9 cases(5.6%) with sibling history and 6 cases(3.7%) with other relatives. 9. In the past history, hypertension led with 124 case s(76.5°%), then C.V.A 37 cases(22.9%) and diabetes mellitus 33 cases(20.4%)(Table 11). 10) In treatment the frequently used herbal recipes were Gamichungshimtang(), BoSimgunbitang( ), Kyuntongdudamtang( ) in 15% of the cerebral hemorrhage cases, respectively; Camichungshimtang( ) in 20% Yangkyeuksan(), Chowishungchumtang(), Yukmichihwangt-ang() in 6%, respectively, in cerebral thrombosis. The most frequently used acupuncture points in C. V. A were shown in Table 12. Taechung(), Habgok ( ), Joksamri(), Oekwan(), Chungjue( ), Jokimueb.(), Kokji(), Taebak() were frequency order used in C.V.A of both cerebral thrombosis and hemorrhage. 11. In admitted C.V.A patient care, it was stressed that the Oriental Medical Hospital plays important roles and, accordingly, the propriety of East-West medical cooperation was addressed. 12. Through classified disease distribution of admitted patients in the Oriental Medicine Hospital the epidemiological epitome of cerebrovascular accidents and other diseases was presented. * East-West medicine denotes a methodology of approaching a creative medicine through cooperation between East-West medicines.

갑상선 세포에서 전사보조활성인자인 CBP와 CIITA의 인터페론-감마 활성 부위에 대한 조절 : CBP and CIITA on GAS(Interferon- γ Activated Site)-Mediated Transcription in Thyroid Cells

채수흥,홍우정,김군순,조영석,김도희,김현진,구본정,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 2001 충남의대잡지 Vol.28 No.1

Background : In the previous stuides, we identified that the interferon-r activated sequence (GAS) in the 5-flanking region of rat ICAM-1 gene is major element for interferon-r-inducible expression of the gene in rat thyroid cells, FRTL-5. We here, investigated the role of transcriptional coactivators, CBP(CREB binding protein) and CⅡTA (class Ⅱ transactivator) in the modulation of the activity of GAS which could interacts with signal transducers and activators of transcription-1 and 3 (STAT1 and STAT3). Methods : The expression of CBP RNA and protein were quantitated in FRTL-5 after stimulation with interferon-r (IFN-r), thyroid stimulating hormone (TSH), forskolin and methimazole. Direct association of CBP with STAT were analyzed by immunoprecipitation. The transcriptional roles of CBP and CⅡTA in the regulation of GAS were assessed by the cotransfection with their expression vectors with reporters; 5-deletion constructs of rat ICAM-1 promoter or 8xGAS-luc constructs, into FRTL-5 thyroid cells. Results : The level of CBP RNA and protein were not changed by the treatment with TSH, IFN-r, forskolin and methimazole in FRTL-5, FRT and BRL liver cells. The CBP could be directly associated with STAT1. Furthermore, the overexpression of CBP significantly increases the both promoter activities; rat ICAM-1 gene promoter which has GAS element and 8xGAS-luc cassette constructs. However, the cotransfection of CⅡTA decreased the constitutive and CBP-mediated transactivation of rat ICAM-1 promoter and 8xGAS-luc cassette constructs. Conclusion : We identified that the two tanscriptional coactivators; CBP and CⅡTA has differential roles in the regulation of transcriptional activity of GAS drived promoter. CBP increases the GAS activity through the direct binding with STAT1, but CⅡTA inhibited the CBP-mediated transactivation of GAS activity.

Molecular MIMO: From Theory to Prototype

Bon-Hong Koo,Changmin Lee,Yilmaz, H. Birkan,Farsad, Nariman,Eckford, Andrew,Chan-Byoung Chae IEEE 2016 IEEE journal on selected areas in communications Vol.34 No.3

<P>In diffusion-based molecular communication, information transport is governed by diffusion through a fluid medium. The achievable data rates for these channels are very low compared to the radio-based communication system, since diffusion can be a slow process. To improve the data rate, a novel multiple-input multiple-output (MIMO) design for molecular communication is proposed that utilizes multiple molecular emitters at the transmitter and multiple molecular detectors at the receiver (in RF communication these all correspond to antennas). Using particle-based simulators, the channel's impulse response is obtained and mathematically modeled. These models are then used to determine interlink interference (ILI) and intersymbol interference (ISI). It is assumed that when the receiver has incomplete information regarding the system and the channel state, low complexity symbol detection methods are preferred since the receiver is small and simple. Thus, four detection algorithms are proposed-adaptive thresholding, practical zero forcing with channel models excluding/including the ILI and ISI, and Genie-aided zero forcing. The proposed algorithms are evaluated extensively using numerical and analytical evaluations.</P>

PERFORMANCE OF THE SRAO 6-METER RADIO TELESCOPE

KOO BON-CHUL,PARK YONG-SUN,HONG SEUNG SOO,YUN HONG-SIK,LEE SANG-GAK,BYUN DO-YOUNG,LEE JUNG-WON,CHOI HAN-KyU,LEE SANG-SUNG,YOON YOUNG-ZOO,KIM KEE-TAE,KANG HYUN WOO,LEE JUNG-EuN The Korean Astronomical Society 2003 Journal of The Korean Astronomical Society Vol.36 No.1

We introduce and describe performance of the 6-meter telescope of Seoul Radio Astronomy Observatory (SRAO). All the softwares and instruments except the antenna structure and its driving system are developed for ourselves. The SIS mixer type receiver resulted in the receiver noise temperature less than 50 K (DSB) over the whole 3-mm radio window. An autocorrelation spectrometer, developed first in Korea, provides maximum 50 MHz band width over 1024 channels. Antenna surface is measured and adjusted using template method and radio holography which resulted in a superb surface accuracy bet-ter than 30${\mu}m$. Accordingly, the aperture and beam efficiences amount to $70\%$ and $75\%$, respectively, largely independent of frequency in the 85 - 115 GHz range. It is also found that telescope pointing errors are less than 10" in both azimuth and elevation and that antenna gain is almost constant against elevation greater than $20^{\circ}$, without adjusting sub-reflector position. The SRAO 6-meter telescope is now fully operational and all these characteristics verify that observations are carried out with high precision and fidelity.

항공 우주 해상 : 시뮬레이터를 이용한 태안비행장 Curved Approach에 대한 고찰

구본수 ( Bon Soo Koo ),전향식 ( Hyang Sig Jun ),정명숙 ( Myeong Sook Jung ),박수복 ( Soo Bog Park ),홍승범 ( Seung Beom Hong ),홍교영 ( Gyo Young Hong ) 한국항행학회 2014 韓國航行學會論文誌 Vol.18 No.4

현재 사용 중인 계기착륙장치(ILS)는 시스템 특성상 동시에 다수의 입항하는 항공기가 사용하기 어렵고, 활주로 방향별로 장비들이 설치되어야 한다. 또한 착륙하는 항공기들이 일정한 구역에서 단일 비행경로만으로 착륙절차가 구성되어야 한다는 한계점이 있다. 이에 항공 교통량이 증가하게 된다면 입항하는 항공기들의 체공 시간이 더욱 증가하게 될 것이다. 이러한 한계점을 보완하기 위해 GNSS를 이용한 착륙시설로 GBAS가 개발 되었다. 본 논문에서는 비행시험 전 시뮬레이터를 이용하여 태안 비행장에서 실제 사용 하고 있는 항공기 착륙절차와 Curved approach를 이용한 절차를 비교 하였다. 비교 결과 Curved approach 절차를 이용하게 되면 기존절차보다 비행시간이 감소되어 연료 및 소음공역회피 등과 같은 효과가 일어 날 수 있을 것으로 판단된다. Current ILS is difficult for the many aircraft to access to the system at the same time because of it`s system. And the equipments should be installed at the direction of every runway. Also, There is limitation that landing procedures must be have of only ILS single course when the aircraft land on the ground. hereupon, The more air traffic exist, the longer delay time of flight be. GBAS using the GNSS has been developed to overcome those limitations. Before flight test in Teean airport, this paper compares the taean approach procedure and curved approach procedure by using the simulator. Comparison study shows that curved approach procedure takes less flight time, low fuel consumpsion and make it possible to avoid noise airspace more than original procedure.