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Effects of shaft angle on cutting tool parameters in internal gear skiving
Koichiro Uriu,Tsukasa Osafune,Takanori Murakami,Morimasa Nakamura,Daisuke Iba,Masami Funamoto,Ichiro Moriwaki 대한기계학회 2017 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.31 No.12
Gear skiving has received considerable attention because of its high productivity, particularly in internal gear cutting, and skiving cutter design methods have been widely investigated. At the beginning of a cutter design process, a shaft angle, a center distance, and the number of teeth are examined as basic parameters for cutting gears. In current gear skiving, a shaft angle is generally set to be approximately 20°; however, the reason for selecting this value has not been clarified. In the present study, the validity of the value of shaft angle is discussed by calculating the cutting tool parameters, such as instantaneous rake angles, clearance angles, cut depths, and cutting speeds at continuously moving cutting points against various shaft angles. Therefore, the widely used value of shaft angle would result in moderate cutting tool parameters. In addition, the cutting force and cutter wear would be low when a cutter axis inclines opposite to the gear helix to be cut.
Remote control experiment of multiple robots using RSNP unit
Koichiro Kato,Yukihiro Nakamura,Nobuto Matsuhira,Masahiko Narita 제어로봇시스템학회 2021 제어로봇시스템학회 국제학술대회 논문집 Vol.2021 No.10
In this study, we developed a robot teleoperation function using a robot service network protocol (RSNP) unit and common operation interface, and experimented using 12 robots. From the teleoperation screen on the web page, the robot can be remotely controlled by buttons while checking the camera image on the robot side. We have confirmed that RSNP communication can be introduced by connecting the developed RSNP unit to the robots in various ways. This allowed us to remotely control not only mobile robots but also communication robots, robot arms, and various other robots from a common communication method and operation screen. In addition, the experiment confirmed the teleoperation of 12 robots and 17 operators. However, the operation method was not sufficient because there was no feedback of the operation amount on the operation screen. We will continue to improve the remote-control system to make it easier for an operator to control robot systems.
Serum Levels of Type 2 Chemokines in Lepromatous Leprosy Patients
Lew, Wook,Nakamura, Koichiro,Tada, Yayoi,Kwahck, Ho,Chang, Soo Kyoung,Tamaki, Kunihiko The Korean Association of Immunobiologists 2002 Immune Network Vol.2 No.4
Background: The type 2 deviated immunological state is predominant in lepromatous leprosy. Erythema nodosum leprosum (ENL) is an immune-complex mediated reaction that typically occurs in lepromatous leprosy. To date, the serum levels of tumor necrosis factor (TNF)-${\alpha}$, interleukin (IL)-2 receptor, IL-10, IL-$1{\beta}$, IL-1 receptor antagonist and monocyte chemoattractant protein-1 (MCP-1) were reported to be higher in lepromatous leprosy. TNF-${\alpha}$ is also known to be higher in ENL, which is reduced after thalidomide treatment. However the serum type 2 chemokine levels in lepromatous leprosy patients have not been reported. Methods: The serum levels of the type 2 chemokines such as thymus and activation-regulated chemokine (TARC), macrophage-derived chemokine (MDC) and eotaxin together with IL-12 and IL-10 in the sera from leprosy patients were detected using an enzyme-linked solvent assay (ELISA) method. Results: The Serum TARC, MDC, eotaxin, IL-10 and IL-12 levels in lepromatous leprosy patients were not significantly different from the normal control levels. The serum levels were not significantly different between the paucibacillary group and multibacillary group. The serum TARC or MDC levels in the ENL patients were more reduced after a treatment containing thalidomide. Conclusion: The type 2 chemokines are not related to the severity of lepromatous leprosy. The larger reducing effect of the TARC or MDC levels in ENL patients by a treatment containing thalidomide suggests the potential role of these chemokines in the development of ENL and the therapeutic mechanism of thalidomide.
Metabolic Syndrome is a Predisposing Factor for Diffuse Idiopathic Skeletal Hyperostosis
Eijiro Okada,Shinichi Ishihara,Koichiro Azuma,Takehiro Michikawa,Satoshi Suzuki,Osahiko Tsuji,Satoshi Nori,Narihito Nagoshi,Mitsuru Yagi,Michiyo Takayama,Takashi Tsuji,Nobuyuki Fujita,Masaya Nakamura 대한척추신경외과학회 2021 Neurospine Vol.18 No.1
Objective: Diffuse idiopathic skeletal hyperostosis (DISH) causes spinal ankylosis, which can result in patients suffering specific spinal fractures that lead to a reduction in the activities of daily life in older patients. Currently, DISH is associated with diabetes mellitus and cardiovascular disease; however, the association between DISH and metabolic syndrome has not been established. The purpose of this study was to investigate a potential association between DISH and metabolic syndrome. Methods: We retrospectively reviewed clinical data from consecutive subjects undergoing the musculoskeletal health medical checkups, and enrolled 327 subjects (174 men and 153 women; mean, 63.4±13.7-years). Subjects who had spinal ankylosis at least 4 contiguous vertebral bodies were classified as the DISH group (n=39) while the others were part of the non-DISH group (n=288). The definition of the metabolic syndrome comes from diagnostic criteria used by the Japanese Society for Internal Medicine. Age, sex, body max index (BMI), hematological evaluation, blood pressure, presence of metabolic syndrome, the visceral fat area on abdominal computed tomography, and spinal epidural lipomatosis (SEL) on magnetic resonance imaging were evaluated. Results: Compared to the non-DISH group, in the DISH group, mean age (DISH group, 74.3 years; non-DISH group, 1.9 years; p<0.001), male prevalence were higher (DISH group, 82.1%; non-DISH group, 49.3%; p<0.001), and BMI was greater (DISH group, 24.8; non-DISH group, 23.0; p=0.006). the metabolic syndrome was more frequently observed in DISH group (28.9%) than in the non-DISH group (16.0%) (p=0.045). The visceral fat area was significantly larger in the DISH group than in the non-DISH group (DISH group, 130.7±58.2 cm2; Non-DISH group, 89.0±48.1 cm2; p<0.001). The prevalence of SEL was similar between the 2 groups (10.3% in the DISH group vs. 8.7% in the non-DISH group; p=0.464). Poisson regression analysis revealed that the metabolic syndrome was significantly associated with DISH with odds ratio of 2.0 (95% confidence interval, 1.0–3.7; p=0.004). Conclusion: Metabolic syndrome was significantly associated with DISH. Our data showed metabolic syndrome is potentially related to DISH.
( Satoshi Takeuchi ),( Hidehisa Saeki ),( Shoji Tokunaga ),( Makoto Sugaya ),( Hanako Ohmatsu ),( Yuichiro Tsunemi ),( Hideshi Torii ),( Koichiro Nakamura ),( Tamihiro Kawakami ),( Yoshinao Soma ),( E 대한피부과학회 2012 Annals of Dermatology Vol.24 No.2
Background: Pruritis caused by atopic dermatitis (AD) is not always well controlled by topical corticosteroid therapy, but use of tacrolimus often helps to soothe such intractable pruritis in clinical settings. Objective: To determine the anti-pruritic efficacy of topical tacrolimus in treating AD in induction and maintenance therapy. Methods: Prior to the study, patients were randomly allocated into two groups, induction therapy followed by tacrolimus monotherapy maintenance, and induction therapy followed by emollient- only maintenance. In the induction therapy, the patients were allowed to use topical tacrolimus and emollients in addition to a low dose (<10 g/week) of topical steroids. Patients showing relief from pruritis were allowed to proceed to maintenance therapy. Recurrence of pruritis in maintenance therapy was examined as a major endpoint. Results: Two-thirds of patients (44/68; 64.7%) showed relief from pruritis after induction therapy. Pruritis recurred in 23.8% (5/21) of the tacrolimus monotherapy group and in 100% (21/21) of the emollient group during maintenance period, a difference that was statistically significant. Conclusion: Use of topical tacrolimus is effective in controlling pruritis of AD compared to emollient. (Ann Dermatol 24(2) 144∼150, 2012)