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      • KCI등재

        “Why Can’t We Be Friends”? An Examination of Academic and Industry Alignment in Sport Sponsorship

        ( Ryan W. Dastrup ),( Todd C. Koesters ),( Stephen L. Shapiro ),( Sung-bae Roger Park ) 한국스포츠정책과학원 2023 International Journal of Applied Sports Sciences Vol.35 No.1

        The purpose of this study is to produce an analysis of content published in both academic literature and industry related publications that specifically examines the theme of sport sponsorship. Scholars suggest a gap between academia and industry, yet it is undetermined how published articles about sponsorship are aligned and why certain topics may overlap in interest where others are independent topics. While a number of other studies have examined content in academic publications, no study has yet been applied comparing industry publications. Our intention is to compare the published academic articles and what is written in industry publications to better understand the content that is being discussed across the various channels, and to see if there is a gap between industry and academia. Findings show academics focused on certain categories while industry focused on others. Within some categories there was a clear distinction in how differently they discussed certain topics. However, some categories did demonstrate balance.

      • KCI등재

        Development of a Novel Imaging Agent for Determining Albumin Uptake in Solid Tumors

        S. Daum,J. P. Magnusson,L. Pes,J. Garcia Fernandez,S. Chercheja,F. Medda,F. I. Nollmann,S. D. Koester,P. Perez Galan,A. Warnecke,K. Abu Ajaj,Felix Kratz 대한핵의학회 2019 핵의학 분자영상 Vol.53 No.3

        Purpose The purpose of this study was to investigate the albumin-binding compound 111In-C4-DTPA as an imaging agent for the detection of endogenous albumin accumulation in tumors. Methods 111In-C4-DTPA was injected in healthy nude mice for pharmacokinetic and biodistribution studies (10 min, 1, 6, 24, and 48 h, n = 4) and subsequently in tumor-bearing mice for single-photon emission computed tomography/X-ray-computed tomography (SPECT/CT) imaging studies. Four different human tumor xenograft models (LXFL529, OVXF899, MAXFTN401, and CXF2081) were implanted subcutaneously unilaterally or bilaterally (n = 4–8). After intravenous administration of 111In-C4-DTPA, SPECT/CT images were collected over 72 h at 4–6 time points. Additionally, gamma counting was performed for the blood, plasma, lungs, heart, liver, spleen, kidneys, muscle, and tumors at 72 h post-injection. Results 111In-C4-DTPA bound rapidly to circulating albumin upon injection, and the radiolabeled albumin conjugate thus formed was stable in murine and human serum. SPECT/CT images demonstrated a time-dependent uptake with a maximum of 2.7– 3.8% ID/cm3 in the tumors at approximately 24 h post-injection and mean tumor/muscle ratios in the range of 3.2–6.2 between 24 and 72 h post-injection. The kidneys and bladder were the predominant elimination organs. Gamma counting at 72 h postinjection showed 1.3–2.5% ID/g in the tumors and mean tumor/muscle ratios in the range of 4.9–9.4. Conclusion 111In-C4-DTPA bound rapidly to circulating albumin upon injection and showed time-dependent uptake in the tumors demonstrating a potential for clinical application as a companion imaging diagnostic for albumin-binding anticancer drugs.

      • MoTe<sub>2</sub> Lateral Homojunction Field-Effect Transistors Fabricated using Flux-Controlled Phase Engineering

        Ma, Rui,Zhang, Huairuo,Yoo, Youngdong,Degregorio, Zachary Patrick,Jin, Lun,Golani, Prafful,Ghasemi Azadani, Javad,Low, Tony,Johns, James E.,Bendersky, Leonid A.,Davydov, Albert V.,Koester, Steven J. American Chemical Society 2019 ACS NANO Vol.13 No.7

        <P>The coexistence of metallic and semiconducting polymorphs in transition-metal dichalcogenides (TMDCs) can be utilized to solve the large contact resistance issue in TMDC-based field effect transistors (FETs). A semiconducting hexagonal (2H) molybdenum ditelluride (MoTe<SUB>2</SUB>) phase, metallic monoclinic (1T′) MoTe<SUB>2</SUB> phase, and their lateral homojunctions can be selectively synthesized <I><I>in situ</I></I> by chemical vapor deposition due to the small free energy difference between the two phases. Here, we have investigated, in detail, the structural and electrical properties of <I>in situ</I>-grown lateral 2H/1T′ MoTe<SUB>2</SUB> homojunctions grown using flux-controlled phase engineering. Using atomic-resolution plan-view and cross-sectional transmission electron microscopy analyses, we show that the round regions of near-single-crystalline 2H-MoTe<SUB>2</SUB> grow out of a polycrystalline 1T′-MoTe<SUB>2</SUB> matrix. We further demonstrate the operation of MoTe<SUB>2</SUB> FETs made on these <I>in situ</I>-grown lateral homojunctions with 1T′ contacts. The use of a 1T′ phase as electrodes in MoTe<SUB>2</SUB> FETs effectively improves the device performance by substantially decreasing the contact resistance. The contact resistance of 1T′ electrodes extracted from transfer length method measurements is 470 ± 30 Ω·μm. Temperature- and gate-voltage-dependent transport characteristics reveal a flat-band barrier height of ∼30 ± 10 meV at the lateral 2H/1T′ interface that is several times smaller and shows a stronger gate modulation, compared to the metal/2H Schottky barrier height. The information learned from this analysis will be critical to understanding the properties of MoTe<SUB>2</SUB> homojunction FETs for use in memory and logic circuity applications.</P> [FIG OMISSION]</BR>

      • KCI등재

        Development and physicochemical characterization of saquinavir mesylate solid dispersions using Gelucire 44/14 or PEG 4000 as carrier

        Thiago Caon,Ricardo Augusto Konig,Ariadne Cristiane Cabral da Cruz,Simone Gonc¸alves Cardoso,Carlos Eduardo Maduro Campos,Silvia Lucia Cuffini,Letı´cia Scherer Koester,Cla´udia Maria Oliveira Simo˜es 대한약학회 2013 Archives of Pharmacal Research Vol.36 No.9

        Solid dispersions of saquinavir mesylate containingeither Gelucire 44/14 or poly(ethylene glycol)(PEG) 4000, or mixtures of each carrier with Tween 80 orpolyvinyl pyrrolidone (PVP) K30 were prepared in order toenhance the drug dissolution rate. These systems wereprepared by the melting method and characterized by X-raypowder diffraction, microscopical techniques, and Ramanspectroscopy aiming to establish a relationship betweenphysicochemical and dissolution properties under differentcooling conditions. Modifications in degree of crystallineorder/disorder over time were observed in preparationswith both carriers. Overall, formulations cooled and stored at -20 C showed less variation in dissolution rates thanthose at 25 C. Although Tween 80 has enhanced theknown self-emulsifying properties of Gelucire 44/14, itscombination with PEG 4000 displayed miscibility problems. The addition of PVP K30 was not the most effectiveapproach in enhancing the dissolution in early steps;however, the drug dissolution was stable after 7 days ofstorage at 25 C. The combination of PEG 4000 and PVPK30 maintained the dissolution properties for 60 and90 days at 25 C/95 % relative humidity and 40 C/75 %(f2 values[50), respectively.

      • KCI등재

        Proton Radiography and Fast Electron Propogation Through Cyliderically Compressed Targets

        R. Jafer,L. Volpe,D. Batani,M. Koenig,S. Baton,E. Brambrink,F. Perez,K. Lancaster,M. Galimberti,R. Heathcote,M. Tolley,Ch. Spindloe,P. Koester,L. Labate,L. Gizzi,C. Benedetti,A. Sgattoni,M. Richetta,J 한국물리학회 2010 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.57 No.21

        The paper describes the key points contained in the short term HiPER (High Power laser Energy Research) experimental road map, as well as the results of two phases of the experiment performed in “HiPER dedicated time slots. Experimental and theoretical results of relativistic electron transport in cylindrically compressed matter are presented. This experiment was achieved at the VULCAN laser facility (UK) by using four long pulse beams (∽4 × 50 J, 1 ns, at 0.53 µm) to compress a hollow plastic cylinder filled with plastic foam of three different densities (0.1, 0.3, and 1 g cm−3). In the first phase of the experiment, protons accelerated by a picosecond laser pulse were used to radiograph a cylinder filled with 0.1 g/cc foam. Point projection proton backlighting was used to measure the degree of compression as well as the stagnation time. Results were compared to those from hard X-ray radiography. Finally, Monte Carlo simulations of proton propagation in cold and compressed targets allowed a detailed comparison with 2D numerical hydro simulations. 2D simulations predict a density of 2-5 g cm−3 and a plasma temperature up to 100 eV at maximum compression. In the second phase of the experiment, a short pulse (10 ps, 160 J) beam generated fast electrons that propagated through the compressed matter by irradiating a nickel foil at an intensity of 5 × 1018 Wcm−2. X-ray spectrometer and imagers were implemented in order to estimate the compressed plasma conditions and to infer the hot electron characteristics. Results are discussed and compared with simulations.

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