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      • Ethnic Differences in Iron Absorption and Its Relevance to Personalized Nutrition

        Kimberly O’Brien 한국식품영양과학회 2021 한국식품영양과학회 학술대회발표집 Vol.2021 No.10

        An individual’s genetic background may influence their biological responses to nutrients and their risk of subsequent adverse health outcomes that are linked to nutritional status. Identifying genes that are associated with nutrient utilization has great potential to improve human health and personalize nutritional intakes. Personalized nutrition approaches are highly relevant to iron homeostasis as both iron deficiency and excess impact risk of chronic disease and adverse health outcomes. Large screening studies have evaluated risk of elevated body iron stores as a function of ancestry and have found that individuals of Asian, particularly East Asian ancestry have the highest risk of elevated body iron stores. This finding is surprising given that the most common genetic mutations associated with iron overload (C282Y and H63D) are nearly absent among Asian individuals. Individuals of East Asian ancestry may also develop iron overload-related diseases such as diabetes at a lower body mass index than typically observed among other ancestry groups. Iron balance is controlled at the level of the enterocyte as humans have no regulatable means of excreting excess iron once absorbed into the body. We recently determined that Asian females absorb significantly more non-heme iron than White females even when controlling for body iron stores. Characterizing ethnic differences in iron absorption and identifying variations in genes that are associated with iron absorption may help target iron supplementation to individuals that will benefit most from these practices and optimize dietary iron intake recommendations. This is particularly important for iron given that prophylactic iron supplementation is often recommended to large subsets of the population during vulnerable life stages. One such example is universal prenatal iron supplementation. While this practice is beneficial in preventing maternal anemia in iron deficient women it may place those with certain genotypes at increased risk of excess body iron stores at maturity.

      • 도시 강우 유출수를 처리하는 침투도랑의 영양물질 처리 메커니즘 분석

        ( Kimberly Ann Yano ),( Nash Jett D. G. Reyes ),( Franz Kevin Geronimo ),이유경 ( Yookyung Lee ),김이형 ( Lee Hyung Kim ) 한국물환경학회 2020 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2020 No.-

        Stormwater runoff contains pollutants such as total suspended solids (TSS), nutrients and heavy metals that can cause harmful effects to the environment. Infiltration trenches (IT) are low impact development (LID) facilities that treat and reduce the volume of stormwater runoff through filtration, sorption processes and soil microbial activities. This study assessed the performance of an IT in treating nitrogen and phosphorus in stormwater runoff and to determine the characteristics and patterns of nutrient transport in an urban catchment area. Water samples from 46 monitored events from May 2009 to September 2019 were analyzed using standard methods for the examination of water and wastewater treatment. Primary hydrologic data were obtained from the Korea Meteorological Administration. The concentrations of total nitrogen (TN) and total phosphorus (TP) on stormwater runoff ranged from 1.7 to 21.2 mg/L and 0.16 to 6.6 mg/L, respectively. Organic forms of nutrients were dominant in urban stormwater runoff and constituted to 61% and 90% of the TN and TP forms, respectively. Greater rainfall intensities resulted to a decreased TN and TP removal efficiency. For a rainfall intensity of 11mm/hr, the recorded removal efficiency for TN and TP only amounted to 34% and 55%, respectively. Low rainfall intensities (<1mm/hr) resulted to 100% removal efficiency. Increasing rainfall depth and intensity resulted to a lower pollutant removal due to the increase in hydraulic loading rate. Filtration, adsorption and sedimentation mechanisms incorporated in the design of IT were found to be the main factors that affected the removal of nutrients within IT. Generally, the IT was capable of reducing nutrient concentrations in urban stormwater runoff. Moreover, hydraulic and hydrologic can greatly influence the performance of IT.

      • 도시 강우 유출수를 처리하는 침투도랑의 영양물질 처리 메커니즘 분석

        ( Kimberly Ann Yano ),( Nash Jett D. G. Reyes ),( Franz Kevin Geronimo ),이유경 ( Yookyung Lee ),김이형 ( Lee Hyung Kim ) 한국물환경학회 2020 한국물환경학회·대한상하수도학회 공동 춘계학술발표회 Vol.2020 No.-

        Stormwater runoff contains pollutants such as total suspended solids (TSS), nutrients and heavy metals that can cause harmful effects to the environment. Infiltration trenches (IT) are low impact development (LID) facilities that treat and reduce the volume of stormwater runoff through filtration, sorption processes and soil microbial activities. This study assessed the performance of an IT in treating nitrogen and phosphorus in stormwater runoff and to determine the characteristics and patterns of nutrient transport in an urban catchment area. Water samples from 46 monitored events from May 2009 to September 2019 were analyzed using standard methods for the examination of water and wastewater treatment. Primary hydrologic data were obtained from the Korea Meteorological Administration. The concentrations of total nitrogen (TN) and total phosphorus (TP) on stormwater runoff ranged from 1.7 to 21.2 mg/L and 0.16 to 6.6 mg/L, respectively. Organic forms of nutrients were dominant in urban stormwater runoff and constituted to 61% and 90% of the TN and TP forms, respectively. Greater rainfall intensities resulted to a decreased TN and TP removal efficiency. For a rainfall intensity of 11mm/hr, the recorded removal efficiency for TN and TP only amounted to 34% and 55%, respectively. Low rainfall intensities (<1mm/hr) resulted to 100% removal efficiency. Increasing rainfall depth and intensity resulted to a lower pollutant removal due to the increase in hydraulic loading rate. Filtration, adsorption and sedimentation mechanisms incorporated in the design of IT were found to be the main factors that affected the removal of nutrients within IT. Generally, the IT was capable of reducing nutrient concentrations in urban stormwater runoff. Moreover, hydraulic and hydrologic can greatly influence the performance of IT.

      • KCI등재

        Ovarian needle aspiration in the diagnosis and management of ovarian masses

        Kimberly Nagamine,Jordan Kondo,Ricky Kaneshiro,Pamela Tauchi-Nishi,Keith Terada 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.4

        Objective: Ovarian needle aspiration and biopsy (ONAB) may be employed for pretreatmentdiagnosis of ovarian malignancies or intraoperatively to facilitate removal of ovarian masses. However, there is reluctance to utilize this procedure due to potential cyst rupture or seedingof malignant cells. The objective of this study was to examine the efficacy of ONAB over a 13-year period at our institution. Methods: Between 2000 and 2013, all ONAB specimens were identified from the Queen'sMedical Center Pathology Department database. All cytologic specimens were reviewedand correlated with histopathologic findings. A retrospective chart review was conducted toretrieve data on clinical course and treatment. Results: This study identified 144 cases of ovarian masses sampled by aspiration or needlebiopsy between 2000 and 2013. Ninety-two (64%) cases had corresponding histopathology,84 (91%) of which were obtained concomitantly. On histology, 12 (13%) cases were malignantand 80 (87%) benign. Three false negative cases were noted; 2 serous borderline tumors and1 mucinous cystadenocarcinoma. These were sampling errors; no diagnostic tumor cells werepresent in the aspirates. Sensitivity and specificity of ONAB in the detection of malignancywere 75% and 100%, respectively. The positive and negative predictive values were 100% and96%, respectively. Conclusion: ONAB represents a valuable tool in the diagnosis of malignancy and treatmentof ovarian masses. In our study, it was highly specific, with excellent positive and negativepredictive value.

      • KCI등재

        Elites and Elitism in American Democracy : At the Convergence of the Elite and the Everyday: The Democratic Potential of Virtual Worlds

        ( Kimberly J. Lau ) 서울대학교 미국학연구소 2010 미국학 Vol.33 No.2

        This paper explores the complex interrelationships and alternative spaces for democracy that emerge when the virtual worlds developed by elite media and entertainment corporations are populated by millions of everyday individuals. In particular, I focus on World of Warcraft (WoW), one of the most popular massively multiplayer online role?playing games ever created, to investigate the convergence of elite media and entertainment forms with the everyday vernacular practices that sustain such forms. Reading the ideological and symbolic environment of Azeroth (WoW`s virtual world) and the game`s structural and technological features while also attending to the multiple ways in which virtual worlds complicate more traditional understandings of the "elite" and the "public sphere," I suggest that such virtual worlds open up possibilities for different models of sociality, communication, and democratic engagement, making possible what Derrida calls "another space for democracy."

      • KCI등재

        Bildung Words to Push Them Down: Roots, Rhizomes, and Metacritical De/Construction in Isabella Valancy Crawford`s Malcolm`s Katie

        ( Kimberly J. Verwaayen ) 한국영미문학페미니즘학회 2011 영미문학페미니즘 Vol.19 No.3

        My paper performs a deconstructive reading of Canadian writer Isabella Valancy Crawford`s major work - her long poem, Malcolm`s Katie: A Love Story (1884). My reading, informed both by and against much of the critical reception of the work to date, understands Malcolm`s Katie as a hermeneutic exercise not simply in nineteenth-century gender-inscribed power relations but in the in/communicability of these using the love story as a dissident narrative strategy. Through a sustained reading against the grain, I argue that Malcolm`s Katie ``doubles its doubled discourse`` by at once participating in and against both patriarchal and feminist ideologies about women`s place in Crawford`s time. I read the text as Katie`s bildungsroman both through and as a metacritical engagement with the im/possibilities of inscribing women`s agency, choice, subjectivity in text, indeed, as story about women`s representation per se: to manipulate a figure from the poem itself, as speech [run] thus two different ways.

      • KCI등재

        Post-pastoral Perspectives of Korean Environment in Contemporary Art and Literature

        Kimberly Chung 계명대학교 한국학연구원 2019 Acta Koreana Vol.22 No.1

        Mixrice, an art collective of artists Yang Ch’ŏlmo [Yang Chul Mo] and Cho Chiŭn [Cho Ji Eun] won the 2016 Korea Artist Prize for their provocative multimedia project that featured a two-channel video installation, titled “The Vine Chronicle.” Centrally documenting the various lives of trees, like a 450- year old Zelkova tree from the village of Kangdong-ri, the video portrays their itinerant lives as they are moved to various sites to fuel capitalist development schemes: camping resorts, apartment complexes and redevelopment sites. Using this exhibit and its unique post-pastoral perspective as a frame, this article explores contemporary perceptions of Korean environment in art and literature. In this study, I am interested in drawing connections among ecocritical artworks and literary works that highlight the dispossession of human and non-human life and the history of rapid South Korean development. These works seek to complicate notions of South Korean development, environmental degradation and migration through a post-pastoral frame.

      • KCI등재

        Responding to North Korean Provocations: Limitations of Sanctions

        Kimberly Ann Elliott 통일연구원 2010 International journal of korean unification studie Vol.19 No.2

        Over the past two decades, economic sanctions and inducements to influence North Korea have not always failed, but the successes have been limited and the obstacles to effectiveness have grown. In general, the application of economic leverage will only be successful if the costs to the target of defying the demands of the sanctioning country or coalition outweigh the costs that the targeted regime perceives it will bear from complying with those demands. Among the factors affecting those costs are the potential economic and political leverage the sanctioner has over the target, the willingness and ability to use that leverage effectively, and the risks that the sanctioner’s demands pose for the target in terms of wealth, power, or political stability and survival. With respect to the sanctions imposed after the sinking of the Cheonan naval ship, only the United States and South Korea took action and it was fairly limited. Even if the sanctions were only intended to punish the North and to send a signal that such behavior would carry a price, the shelling of Yeonpyeong island in November is a further setback.

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