UN / CEFACT 전자문서의 XML 변환규칙

정용규(Yong-Gyu Jung),김운섭(Un-Seob Kim) 한국정보과학회 2002 한국정보과학회 학술발표논문집 Vol.29 No.1A

전자문서교환(EDI, Electronic)은 기업과 기업간에 컴퓨터와 컴퓨터의 통신을 통하여 필요한 거래문서를 구조화된 형식으로 교환하여 업무를 처리하는 방식을 말한다. 그동안 EDI 표준은 북미를 중심으로 한 ANSI X.12를 시작으로, 이에 대응되는 유럽중심의 UN/CEFACT 표준이 제정되었다. UN/CEFACT로 표준을 통합하기로 합의한 양대 표준은 또 다른 XML환경을 접하게 되었다. ISO TC154에서는 UN/CEFACT전자문서의 XML변환에 관한 논의하게 되었으나 표준으로 권고되지 못하고 있는 실정이다. 이런 표준간 연동의 문제를 위하여 본 논문에서는 Speaking Tag방식과 UN/CEFACT Tag방식의 두가지를 제안하며 각각에 대해 변환규칙을 제안한다.

Activation of the nucleotide excision repair pathway by crude oil exposure: A translational study from model organisms to the Hebei Spirit Oil Spill Cohort

Kim, Youngho,Jeong, Jaeseong,Chatterjee, Nivedita,Yim, Un Hyuk,Kwon, Jung-Hwan,Park, Myung-Sook,Choi, Jinhee Elsevier 2019 Environmental pollution Vol.254 No.2

<P><B>Abstract</B></P> <P>In order to gain insight into the human health implications of the Hebei Spirit Oil Spill (HSOS), the mechanism of toxicity of the Iranian heavy crude (IHC), the main oil component in the HSOS was investigated in <I>Caenorhabditis elegans and</I> zebrafish<I>.</I> The identified mechanism was translated to humans using blood samples from Taean residents, who experienced HSOS with different levels of exposure to the spill. <I>C. elegans</I> TF RNAi screening with IHC oil revealed the nucleotide excision repair (NER) pathway as being significantly involved by oil exposure. To identify the main toxicity contributors within the chemical mixture of the crude oil, further studies were conducted on <I>C. elegans</I> by exposure to C3-naphthalene, an alkylated polycyclic aromatic hydrocarbon (PAH), which constitutes one of the major components of IHC oil. Increased expression of NER pathway genes was observed following exposure to the IHC oil, C3-naphthalene enriched fraction and C3-naphthalene. As the NER pathway is conserved in fish and humans, the same experiment was conducted in zebrafish, and the data were similar to what was seen in <I>C. elegans</I>. Increased expression of NER pathway genes was observed in human samples from the high exposure group, which suggests the involvement of the NER pathway in IHC oil exposure. Overall, the study suggests that IHC oil may cause bulk damage to DNA and activation of the NER system and Alkylated PAHs are the major contributor to DNA damage. Our study provides an innovative approach for studying translational toxicity testing from model organisms to human health.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Human health implications of HSOS was investigated in <I>C.elegans</I>, zebrafish and human blood samples from HSOS cohort. </LI> <LI> <I>C. elegans</I> transcription factors RNAi library screening revealed NER pathway as a mechanism of toxicity of crude oil. </LI> <LI> Alkylated PAHs seemed to be the major contributors of crude oil exposure-induced DNA damage and repair. </LI> <LI> Alteration of NER pathway by crude oil exposure was a conserved response in C.elegans, zebrafish and human cohort samples. </LI> <LI> Toxicological and epidemiological approaches can be complementarily used for identifying mechanism of toxicity of chemicals and their consequences to human health. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Trends in Incidence and Treatment of Herniated Lumbar Disc in Republic of Korea : A Nationwide Database Study

Jung, Jong-myung,Lee, Si Un,Hyun, Seung-Jae,Kim, Ki-Jeong,Jahng, Tae-Ahn,Oh, Chang Wan,Kim, Hyun-Jib The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.1

Objective : This study aimed to determine the incidence and analyze trends of the herniated lumbar disc (HLD) based on a national database in the Republic of Korea (ROK) from January 2008 to December 2016. Methods : This study was a retrospective analysis of data obtained from the national health-claim database provided by the National Health Insurance Service for 2008-2016 using the International Classification of Diseases. The crude incidence and age-standardized incidence of HLD were calculated, and additional analysis was conducted according to age and sex. Changes in trends in treatment methods and some treatments were analyzed using the Korean Classification of Diseases procedure codes. Results : The number of patients diagnosed with HLD was 472245 in 2008 and increased to 537577 in 2012; however, it decreased to 478697 in 2016. The pattern of crude incidence and the standardized incidence were also similar. Overall, the incidence of HLD increased annually for the 30s, 40s, 50s, and 70s until 2012 and then decreased. However, the incidence of HLD for the 80s continued to increase. The crude incidence of HLD in female patients exceeded that of male patients in their middle age (30s or 40s) and was 1.5-1.6 times higher than in male patients in their 60s. The total number of open discectomy (OD) increased from 71598 in 2008 to 93942 in 2012 and then decreased to 85846 in 2016. The rate of younger patients (the 20s, 30s, and 40s) who underwent OD was decreased, and the rate of younger patients who underwent percutaneous endoscopic lumbar discectomy was increased. However, the rate of older patients (the 70s and 80s) who underwent OD was continuously increased. Conclusion : This nationwide data on HLD from 2008 to 2016 in the ROK demonstrated that the crude incidence and the standardized incidence increased until 2012 and then decreased. The annual crude incidence was different according to age and sex. These findings may be considered when deciding future health policy, especially in countries with a similar national health insurance system (or with plans to adopt).

Fatty Acid Composition and Contents of Functional Compounds in Perilla Germplasm

Kim Jung-In,Lee Myoung-Hee,Oh Eun-Young,Oh Ki-Won,Kim Sung-Up,Pae Suk-Bok,Asekova Sovetgul,Yeo Un-Sang,Kwak Do-Yeon 한국작물학회 2017 한국작물학회 학술발표대회 논문집 Vol.2017 No.-

Virus Incidence of Sweet Potato in Korea from 2011 to 2014

Kim, Jaedeok,Yang, Jung wook,Kwak, Hae-Ryun,Kim, Mi-Kyeong,Seo, Jang-Kyun,Chung, Mi-Nam,Lee, Hyeong-un,Lee, Kyeong-Bo,Nam, Sang Sik,Kim, Chang-Seok,Lee, Gwan-Seok,Kim, Jeong-Soo,Lee, Sukchan,Choi, Hon The Korean Society of Plant Pathology 2017 Plant Pathology Journal Vol.33 No.5

A nationwide survey was performed to investigate the current incidence of viral diseases in Korean sweet potatoes for germplasm and growing fields from 2011 to 2014. A total of 83.8% of the germplasm in Korea was infected with viruses in 2011. Commercial cultivars that were used to supply growing fields were infected at a rate of 62.1% in 2012. Among surveyed viruses, the incidence of five Potyvirus species that infect sweet potato decreased between 2012 and 2013, and then increased again in 2014. Representatively, the incidence of Sweet potato feathery mottle virus (SPFMV) was 87.0% in 2012, 20.7% in 2013 and then increased to 35.3% in 2014. Unlike RNA viruses, DNA viruses were shown to decrease continuously. The incidence of Sweet potato leaf curl virus (SPLCV) was 5.5% in 2003, 59.5% in 2011, and 47.4% in 2012. It then decreased continuously year by year to 33.2% in 2013, and then 25.6% in 2014. While the infection rate of each virus species showed a tendency to decline, the virus infection status was more variable in 2013 and 2014. Nevertheless, the high rate of single infections and mixed infection combinations were more variable than the survey results from 2012. As shown in the results from 2013, the most prevalent virus infection was a single infection at 27.6%, with the highest rate of infection belonging to sweet potato symptomless virus-1 (SPSMV-1) (12.9%). Compared to 2013, infection combinations were more varied in 2014, with a total of 122 kinds of mixed infection.

Production of linear α-olefin 1-octene via dehydration of 1-octanol over Al₂O₃ catalyst

Kim, Young-eun,Im, Hyo Been,Jung, Un Ho,Park, Ji Chan,Youn, Min Hye,Jeong, Heon-Do,Lee, Dong-Wook,Rhim, Geun Bae,Chun, Dong Hyun,Lee, Ki Bong,Koo, Kee Young Elsevier 2019 Fuel Vol.256 No.-

<P><B>Abstract</B></P> <P>The linear α-olefin 1-octene was produced via the dehydration of 1-octanol over Al<SUB>2</SUB>O<SUB>3</SUB> catalysts. The effect of calcination temperature on the characteristics of an Al<SUB>2</SUB>O<SUB>3</SUB> catalyst and its activity in the dehydration of 1-octanol to 1-octene was investigated. Al<SUB>2</SUB>O<SUB>3</SUB> catalysts calcined at various temperatures (250, 500, 750, 1000 °C) were evaluated at 300–400 °C with a liquid hourly space velocity (LHSV) of 7–56 h<SUP>−1</SUP>. XRD, BET, <SUP>27</SUP>Al-NMR, Py-FTIR, and NH<SUB>3</SUB>-TPD analyses indicated that the calcination temperature affected the crystal phase, surface area, occupancy of the coordinated Al<SUP>3+</SUP> ion, and acidic properties of Al<SUB>2</SUB>O<SUB>3</SUB> catalysts. Upon calcination at temperatures >750 °C, the surface area of Al<SUB>2</SUB>O<SUB>3</SUB> catalysts reduced due to γ-Al<SUB>2</SUB>O<SUB>3</SUB> to θ-Al<SUB>2</SUB>O<SUB>3</SUB> phase transition. The changes in the crystal phase decreased the surface area, which correlated to the acidity of the Al<SUB>2</SUB>O<SUB>3</SUB> catalyst. The distribution of unsaturated Al<SUP>3+</SUP> ions acting as LAS on the catalyst surface increased with increasing calcination temperature, but decreased above 750 °C calcination temperature due to the diminishing surface area. The Al<SUB>2</SUB>O<SUB>3</SUB> catalyst calcined at 500 °C showed the highest 1-octanol conversion in the dehydration of 1-octanol. High 1-octene selectivity was maintained while the isomer ratio decreased at a high LHSV of 56 h<SUP>−1</SUP>.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Linear α-olefin 1-octene produced via dehydration of 1-octanol over Al<SUB>2</SUB>O<SUB>3</SUB> catalyst. </LI> <LI> Changes in crystal phase affected the strong LAS and catalytic activity of Al<SUB>2</SUB>O<SUB>3</SUB>. </LI> <LI> Increased strong LAS improved 1-octanol conversion and 1-octene yield. </LI> <LI> Octene isomers decreased while DOE increased at higher LHSV. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Alterations of Epidermal Lipid Profiles and Skin Microbiome in Children With Atopic Dermatitis

Kim Jihyun,Kim Byung Eui,Goleva Elena,Berdyshev Evgeny,배재웅,Kim Seokjin,Kim Hye-young,Lee Un Ha,Kim Myoung Shin,Jung Minyoung,Kim Hyunmi,Lee Jinyoung,Donald Y.M. Leung,Ahn Kangmo 대한천식알레르기학회 2023 Allergy, Asthma & Immunology Research Vol.15 No.2

Purpose: We aimed to investigate epidermal lipid profiles and their association with skin microbiome compositions in children with atopic dermatitis (AD). Methods: Specimens were obtained by skin tape stripping from 27 children with AD and 18 healthy subjects matched for age and sex. Proteins and lipids of stratum corneum samples from nonlesional and lesional skin of AD patients and normal subjects were quantified by liquid chromatography tandem mass spectrometry. Skin microbiome profiles were analyzed using bacterial 16S rRNA sequencing. Results: Ceramides with nonhydroxy fatty acids (FAs) and C18 sphingosine as their sphingoid base (C18-NS-CERs) N-acylated with C16, C18 and C22 FAs, sphingomyelin (SM) N-acylated with C18 FAs, and lysophosphatidylcholine (LPC) with C16 FAs were increased in AD lesional skin compared to those in AD nonlesional skin and that of control subjects (all P < 0.01). SMs N-acylated with C16 FAs were increased in AD lesional skin compared to control subjects (P < 0.05). The ratio of NS-CERs with long-chain fatty acids (LCFAs) to short-chain fatty acids (SCFAs) (C24-32:C14-22), the ratio of LPC with LCFAs to SCFAs (C24-30:C16-22) as well as the ratio of total esterified omega-hydroxy ceramides to total NS-CERs were negatively correlated with transepidermal water loss (rho coefficients = −0.738, −0.528, and −0.489, respectively; all P < 0.001). The proportions of Firmicutes and Staphylococcus were positively correlated to SCFAs including NS ceramides (C14-22), SMs (C17-18), and LPCs (C16), while the proportions of Actinobacteria, Proteobacteria, Bacteroidetes, Corynebacterium, Enhydrobacteria, and Micrococcus were negatively correlated to these SCFAs. Conclusions: Our results suggest that pediatric AD skin shows aberrant lipid profiles, and these alterations are associated with skin microbial dysbiosis and cutaneous barrier dysfunction.

Mitigation of Greenhouse Gas Emissions (GHGs) by Water Management Methods in Rice Paddy Field

Kim, Gun-Yeob,Park, Woo-Kyun,Lee, Sun-Il,Lee, Jong-Sik,Choi, Eun-Jung,Na, Un-sung,Jang, Hee-Young,Suh, Sang-Uk 한국토양비료학회 2015 한국토양비료학회지 Vol.48 No.5

Environmental effect of water-saving irrigation on the emissions of greenhouse gases (GHGs) has not been well investigated. The objective of this study was to measure the effect of water-saving irrigation on GHGs as well as water use and rice production yield in paddy field condition in Korea. Four experimental runoff plots of 4x35 m in size were prepared at an existing paddy field. GHGs emission was measured during the 2012~2013 growing seasons while a Japonica rice variety was cultivated. Four different water management methods, 1) Continuous Flooding (CF), 2) Intermittent Drainage (ID), 3) Water Saving (WS), and 4) CF+WS, were used during a rice growing season to compare the effects of water management methods on GHGs emission. CF method is flooding all the time, ID method makes paddy water drained 40 days after transplanting for about two weeks, WS method maintains 2~3 cm water-level, which should be refilled when the water-level decreased to about 0 cm, and CF+WS method combines CF method before 30 days after transplanting (DAT) and WS method after 30 DAT. Regardless of water management methods, paddy field water was drained about 30 days before harvest. Amount of GHGs emission from WS plot was reduced by 69.3% compared to that from CF plot and by 59.0% compared to that from ID plot. Amount of GHGs emission from CF+WS plot was reduced by 60.7% compared to that from CF plot and by 47.5% compared to that from ID plot. Weed occurrence in CF+WS plots was reduced to 62.2% in comparison with the WS plot, implying that CF+WS plot showed the best effect to mitigation of the greenhouse gas emission in the atmosphere.

Cytotoxic Components from the Dried Rhizomes of Zingiber officinale Roscoe

Kim, Ju-Sin,Lee, Sa-Im,Park, Hye-Won,Yang, Jae-Heon,Shin, Tae-Yong,Kim, Youn-Chul,Baek, Nam-In,Kim, Sung-Hoon,Choi, Sang-Un,Kwon, Byoung-Mog,Leem, Kang-Hyun,Jung, Mun-Yhung,Kim, Dae-Keun 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.4

Five compounds were isolated from the chloroform-soluble fraction of the methanolic extract of the dried rhizomes of Zingiber officinale (Zingiberaceae) through repeated column chromatography. Their chemical structures were elucidated as 4-, 6-, 8-, and 10-gingerols, and 6-shogaol using spectroscopic analysis. Among the five isolated compounds, 6-shogaol exhibited the most potent cytotoxicity against human A549, SK-OV-3, SK-MEL-2, and HCT15 tumor cells. 6-shogaol inhibited proliferation of the transgenic mouse ovarian cancer cell lines, C1 (genotype: $p53^{-/-}$, c-myc, K-ras) and C2 (genotype: $p53^{-/-}$, c-myc, Akt), with $ED_{50}$ values of 0.58 ${\mu}M$ (C1) and 10.7 ${\mu}M$ (C2).

Synthesis of Novel Poly(amido ethylenimine) (PAMEIM) Dendrimer and Its Self-assembly with Plasmid DNA

Kim, Tae-Il,Baek, Jung-Un,Bai, Cheng-Zhe,Park, Jong-sang Korean Chemical Society 2006 Bulletin of the Korean Chemical Society Vol.27 No.11