神經性 無慾症에 關한 臨床的 考察 및 觀察 (Ⅰ)

金憲秀,李吉弘,羅澈,姜信三,張棟山,安宰熙,閔秉根 중앙대부설한국의과학연구소 1983 한국의과학 Vol.15 No.1

經緯系의 收縮에 關한 硏究

金熙山,李在坤 忠南大學校 1962 論文集 Vol.2 No.-

In general, the contraction of thread in a fabric can be determined by the following factors such as tension, ends or picks per inch, weaves, counts and turns per inch. In order to simplify the calculation we ignored the effects of tension and twists on contraction, and classified the fabric as follows: a) a square fabric b) a fabric whose angle of curvature of warp or weft proceeds the other. c) a fabric whose angle of curvature of warp or weft slightly differes from the other. Firstly, we determined the maximum possible density of warp or weft as follows: D=1/cosθ(de+df) where θ; angle of curvature de; dia. of warp df; dia. of weft D; maximum possible density of warp and weft. The results are as follows L = {I×C×(de+df)×n/D}×D/N where L; original length of warp or weft in a unit length of fabric. I; number of curvature in a repeat due to weaves. C; constant of angle of curvature. n; number of threads that continuously float in a repeat due to weave. And on the variation of tension during weaving we analysed the variation of tension due to three principal motion of loom and classified the nature of variation as follows; such as a) tension which varies continuously during weaving b) tension which varies intermittenly during weaving And summerized as follows; A) tension which varies according to shedding and beating motion varies intermittenly B) tension which added to the warpbeam increases by the decrease of warp beam dia. C) tension which varies according to letting off and taking up motion varies intermittently or continuously by the mechanism.

지역별 하천수에너지 부존량 및 이용가능성에 관한 조사연구

허재영,김산 대전대학교 산업기술연구소 1998 산업기술연구소 論文集 Vol.9 No.2

River water which is one of important unused energy resources has been utilized as cooling water in industrial factories for a long time. The temperature of river water is higher than air in the summer season and vice versa in the winter season. In addition, the river water temperature is relatively stable. From these features, the river water has been expected as alternative cooling and heating heat sources with the development of the heat pump techniques. To utilize the river water as heat source, it is important to establish the standard method for estimating the quantity of river water converted into energy and evaluate the available quantity accurately and on a realistical basis. In this study, the standardization of estimating method is attempted and then the quantity of unused energy of river water is estimated regionally and its energy saving effect and potential are discussed.

노화와 간경변이 인체의 적혈구, 혈장 및 위 점막의 Glutathione 농도와 Glutathione Peroxidase 활성도에 대해 미치는 영향

백광호,김종혁,백일현,한태호,박현주,박상훈,서중산,박충기,유재영 대한노인병학회 2001 대한노인병학회지 Vol.5 No.3

레이저 재료 가공을 위한 광폭빔 광학 장치

전병철,조응산,김재도 한국레이저가공학회 1998 한국레이저가공학회지 Vol.1 No.1

A new wide laser beam optical system for the laser materials processing has been developed with a polygonal mirror. It consists of polygonal mirror and cooling part that prevents the surface of rotating polygonal mirror from damage by heat. The polygonal mirrors have been designed and made as 24 and 30 facets in pyramid type. This system provides a uniform linear laser heat source with the surface scanning width from 15 to 50mm according to the scanning height. To examine the wide laser beam, He-Ne laser is used. Also, Acryl is used to confirm the laser beam pattern by bum-pattern print. to analyze the energy distribution of the wide laser beam, empirical values and theoretical values are compared and discussed. To improve the efficiency of the wide laser beam optical system, methods are suggested by the optical theories. For larger area processing like turbine blade, drawing roller, cold roller and guide plate, optimal overlapping locations have been calculated and analyzed by geometric and optical theories.

Measurement of the thermal expansion of space structures using fiber Bragg grating sensors and displacement measuring interferometers

Kim, Hong-Il,Yoon, Jae-San,Kim, Hong-Bae,Han, Jae-Hung IOP Pub 2010 Measurement Science and Technology Vol.21 No.8

<P>A thermal deformation measurement system, composed of fiber Bragg grating (FBG) sensors for strain measurement and a displacement measuring interferometer (DMI) system for accurate specimen expansion data acquisition, was prepared and installed in a vacuum chamber where the temperature of the test specimen can be controlled to simulate space environments. The DMI system, which consists of two heterodyne interferometers, a laser head, electronics and a thermally stable specimen base made of fused silica, was used to validate the thermal expansions of the specimens measured by the FBG sensors. We measured the average coefficient of thermal expansion (CTE) of an Invar specimen, known as a thermally stable material, using both the FBG sensors and the DMI system in vacuum conditions from 20 °C to 40 °C. The CTE results of the Invar specimen were found to be 1.226 × 10<SUP>−6</SUP> K<SUP>−1</SUP> and 1.298 × 10<SUP>−6</SUP> K<SUP>−1</SUP> based on the FBG and DMI measurements, respectively. The present results show that it is possible to precisely measure the thermal deformation of a specimen or structure in space environments using FBG sensors.</P>

Self-Assembled Nanoparticles of Bile Acid-Modified Glycol Chitosans and Their Applications for Cancer Therapy

Kim Kwangmeyung,Kim Jong-Ho,Kim Sungwon,Chung Hesson,Choi Kuiwon,Kwon Ick Chan,Park Jae Hyung,Kim Yoo-Shin,Park Rang-Won,Kim In-San,Jeong Seo Young The Polymer Society of Korea 2005 Macromolecular Research Vol.13 No.3

This review explores recent works involving the use of the self-assembled nanoparticles of bile acid-modified glycol chitosans (BGCs) as a new drug carrier for cancer therapy. BGC nanoparticles were produced by chemically grafting different bile acids through the use of l-ethyl-3-(3-dimethylaminopropyl)-carbodiimide (EDC). The precise control of the size, structure, and hydrophobicity of the various BGC nanoparticles could be achieved by grafting different amounts of bile acids. The BGC nanoparticles so produced formed nanoparticles ranging in size from 210 to 850 nm in phosphate-buffered saline (PBS, pH=7.4), which exhibited substantially lower critical aggregation concentrations (0.038-0.260 mg/mL) than those of other low-molecular-weight surfactants, indicating that they possess high thermodynamic stability. The SOC nanoparticles could encapsulate small molecular peptides and hydrophobic anticancer drugs with a high loading efficiency and release them in a sustained manner. This review also highlights the biodistribution of the BGC nanoparticles, in order to demonstrate their accumulation in the tumor tissue, by utilizing the enhanced permeability and retention (EPR) effect. The different approaches used to optimize the delivery of drugs to treat cancer are also described in the last section.

A study on an efficient prediction of welding deformation for T-joint laser welding of sandwich panel PART I : Proposal of a heat source model

Kim, Jae Woong,Jang, Beom Seon,Kim, Yong Tai,Chun, Kwang San The Society of Naval Architects of Korea 2013 International Journal of Naval Architecture and Oc Vol.5 No.3

The use of I-Core sandwich panel has increased in cruise ship deck structure since it can provide similar bending strength with conventional stiffened plate while keeping lighter weight and lower web height. However, due to its thin plate thickness, i.e. about 4~6 mm at most, it is assembled by high power $CO_2$ laser welding to minimize the welding deformation. This research proposes a volumetric heat source model for T-joint of the I-Core sandwich panel and a method to use shell element model for a thermal elasto-plastic analysis to predict welding deformation. This paper, Part I, focuses on the heat source model. A circular cone type heat source model is newly suggested in heat transfer analysis to realize similar melting zone with that observed in experiment. An additional suggestion is made to consider negative defocus, which is commonly applied in T-joint laser welding since it can provide deeper penetration than zero defocus. The proposed heat source is also verified through 3D thermal elasto-plastic analysis to compare welding deformation with experimental results. A parametric study for different welding speeds, defocus values, and welding powers is performed to investigate the effect on the melting zone and welding deformation. In Part II, focuses on the proposed method to employ shell element model to predict welding deformation in thermal elasto-plastic analysis instead of solid element model.

Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel

Kim, Jong-Ho,Kim, Yoo-Shin,Kim, Sungwon,Park, Jae Hyung,Kim, Kwangmeyung,Choi, Kuiwon,Chung, Hesson,Jeong, Seo Young,Park, Rang-Woon,Kim, In-San,Kwon, Ick Chan Elsevier 2006 Journal of controlled release Vol.111 No.1-2

<P><B>Abstract</B></P><P>Self-assembled nanoparticles based on hydrophobically modified glycol chitosan (HGC) were prepared as a carrier for paclitaxel. HGC conjugates were prepared by chemically linking 5β-cholanic acid to glycol chitosan chains using 1-ethyl-3-(3-dimethylaminopropyl)-carbodiimide chemistry. In phosphate-buffered saline (PBS; pH 7.4), the synthesized HGC conjugates formed nano-sized particles with a diameter of 200 nm and exhibited high thermodynamic stability as reflected by their low critical aggregation concentration (0.03 mg/ml). Paclitaxel was efficiently loaded into HGC nanoparticles up to 10 wt.% using a dialysis method. The paclitaxel-loaded HGC (PTX-HGC) nanoparticles were 400 nm in diameter and were stable in PBS for 10 days. These PTX-HGC nanoparticles also showed sustained release of the incorporated of paclitaxel (80% of the loaded dose was released in 8 days at 37 °C in PBS). Owing to sustained release, the PTX-HGC nanoparticles were less cytotoxic to B16F10 melanoma cells than free paclitaxel formulated in Cremophor EL. Injection of PTX-HGC nanoparticles into the tail vein of tumor-bearing mice prevented increases in tumor volume for 8 days. Finally, PTX was less toxic to the tumor-bearing mice when formulated in HGC nanoparticles than when formulated with Cremophor EL.</P>

A study on an efficient prediction of welding deformation for T-joint laser welding of sandwich panel PART I

Jae Woong Kim,Beom Seon Jang,Yong Tai Kim,Kwang San Chun 대한조선학회 2013 International Journal of Naval Architecture and Oc Vol.5 No.3

The use of I-Core sandwich panel has increased in cruise ship deck structure since it can provide similar bending strength with conventional stiffened plate while keeping lighter weight and lower web height. However, due to its thin plate thickness, i.e. about 4~6 mm at most, it is assembled by high power CO2 laser welding to minimize the welding deformation. This research proposes a volumetric heat source model for T-joint of the I-Core sandwich panel and a method to use shell element model for a thermal elasto-plastic analysis to predict welding deformation. This paper, Part I, focuses on the heat source model. A circular cone type heat source model is newly suggested in heat transfer analysis to realize similar melting zone with that observed in experiment. An additional suggestion is made to consider negative defocus, which is commonly applied in T-joint laser welding since it can provide deeper penetration than zero defocus. The proposed heat source is also verified through 3D thermal elasto-plastic analysis to compare welding deformation with experimental results. A parametric study for different welding speeds, defocus values, and welding powers is performed to investigate the effect on the melting zone and welding deformation. In Part II, focuses on the proposed method to employ shell element model to predict welding deformation in thermal elasto-plastic analysis instead of solid element model.