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        Ultrasonographic Resistive Index of the Cranial Pancreaicoduodenal Artery in Normal Conscious Dogs

        Ki-DongEom,Hae-oonLee,Yun-sangSeong,Jeong-minLee,Jong-wonLee,Tae-hoOh 한국임상수의학회 2003 한국임상수의학회지 Vol.20 No.3

        The purpose of this study was to determine the range of resistive index(RI) of the cranial pancreaticoduodenal artery(cPDA) in the normal dog's and to assess the possibility of clinical application of RI for diagnosing a pancreatitis. Five patients with acute pancreatitis and 17 healthy adult beagle dogs were used. Duplex color Doppler ultrasonographic examination was performed by using a real-time scanner with 11-MHz linear-array transducer. The dogs were restrained in dorsal recumbency without the use of chemical agent. The mean RI of the normal pancreas(0.63±0.04) was significantly(t=5.79, p=0.001) different from acute pancreatitis dog(0.75±0.04). Duplex color Doppler ultrasonography was an useful technique for detecting and measuring RI of the cPDA. The evaluation of RI of the cPDA may be a valuable supportive diagnostic procedure for evaluating the pancreatitis or suspected in dogs.

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        Characterization of Cell Wall Proteins from the soo1-1/ret1-1 Mutant of Saccharomyces cerevisiae

        Dong-WonLee,Ki-HyunKim,Se-ChulChun,Hee-MoonPark 한국미생물학회 2002 The journal of microbiology Vol.40 No.3

        In order to investigate the function of Soo1p/α-COP during post-translational modification and intracellular transport of cell wall proteins in Saccharomyces cerevisiae, cell wall proteins from the soo1-1/ ret1-1 mutant cells were analyzed. SDS-PAGE analysis of biotin labeled cell wall proteins suggested that the soo1-1 mutation impairs post-translational modification of cell wall proteins, such as N- and/ or O-glycosylation. Analysis of cell wall proteins with antibodies against β-1,3-glucan and β-1,6-glucan revealed alteration of the linkage between cell wall proteins and β-glucans in the soo1-1 mutant cells. Compositional sugar analysis of the cell wall proteins also suggested that the soo1-1 mutation impairs glycosylation of cell wall protein in the ER, which is crucial for the maintenance of cell wall integrity.

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        CMOS Delta-Sigma Frequency Synthesizer with a New Frequency Divider and a Simpli ed MASH Structure

        Soo-HwanKim,Min-SunKeel,Ki-WonLee,Suk-KiKim,Shin-IlLim 한국물리학회 2002 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.41 No.6

        This paper describes a CMOS implementation of a fractional-N frequency synthesizer adopting a new frequency divider and a new simplified 3-stage MASH (multistage noise shaping) delta-sigma modulator. All functional blocks, except for the low-pass filter (LPF), are integrated on a chip. A simple frequency divider architecture with a digital comparator and a `modulus mapping circuit' in a delta-sigma modulator is suggested for a lower hardware complexity and less power consumption. The proposed fractional-N frequency synthesizer shows a rapid switching time of 2.8 $\mu$s at a 60-MHz frequency step with inherent high reference frequency and a wide loop bandwidth. The tuning range of the voltage-controlled oscillator (VCO) is 1.6$\sim$2.1 GHz in the measured results. The measured VCO phase noise is as low as $-$110.27 dBc/Hz at a 600-kHz offset and $-$122.99 dBc/Hz at a 7.5-MHz offset. The measured fractional spur level is $-$101.6 dBc. The total power consumption is 20.2 mW with a 2.5 V single power supply. The synthesizer is implemented in a 0.25-$\mu$m standard CMOS process (1-poly, 5-metal) and occupies an active area of 760$\times$1280 $\mu$m.

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