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Difference image photometry with bright variable backgrounds
Kerins, E.,Darnley, M. J.,Duke, J. P.,Gould, A.,Han, C.,Newsam, A.,Park, B. G.,Street, R. Blackwell Publishing Ltd 2010 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.409 No.1
<P>ABSTRACT</P><P>Over the last two decades the Andromeda galaxy (M31) has been something of a test-bed for methods aimed at obtaining accurate time-domain relative photometry within highly crowded fields. Difference imaging methods, originally pioneered towards M31, have evolved into sophisticated methods, such as the optimal image subtraction (OIS) method of Alard & Lupton, that today are most widely used to survey variable stars, transients and microlensing events in our own Galaxy. We show that modern difference image analysis (DIA) algorithms such as OIS, whilst spectacularly successful towards the Milky Way bulge, may perform badly towards high surface brightness targets such as the M31 bulge. Poor results can occur in the presence of common systematics which add spurious flux contributions to images, such as internal reflections, scattered light or fringing. Using data from the Angstrom Project microlensing survey of the M31 bulge, we show that very good results are usually obtainable by first performing careful photometric alignment prior to using OIS to perform point spread function (PSF) matching. This separation of background matching and PSF matching, a common feature of earlier M31 photometry techniques, allows us to take full advantage of the powerful PSF matching flexibility offered by OIS towards high surface brightness targets. We find that difference images produced this way have noise distributions close to Gaussian, showing significant improvement upon results achieved using OIS alone. We show that with this correction light curves of variable stars and transients can be recovered to within ∼10 arcsec of the M31 nucleus. Our method is simple to implement and is quick enough to be incorporated within real-time DIA pipelines. We also demonstrate that OIS is remarkably robust even when, as in the case of the central regions of the M31 bulge, the sky density of variable sources approaches the confusion limit.</P>
Kerins, E.,Darnley, M. J.,Duke, J. P.,Gould, A.,Han, C.,Jeon, Y.-B.,Newsam, A.,Park, B.-G. Blackwell Science Ltd 2006 Monthly notices of the Royal Astronomical Society Vol.365 No.4
<P>ABSTRACT</P><P>The Andromeda Galaxy Stellar Robotic Microlensing Project (The Angstrom Project) aims to use stellar microlensing events to trace the structure and composition of the inner regions of the Andromeda Galaxy (M31). We present microlensing rate and time-scale predictions and spatial distributions for stellar and sub-stellar lens populations in combined disc and barred bulge models of M31. We show that at least half of the stellar microlenses in and around the bulge are expected to have characteristic durations between 1 and 10 d, rising to as much as 80 per cent for brown-dwarf dominated mass functions. These short-duration events are mostly missed by current microlensing surveys that are looking for Macho candidates in the M31 dark matter halo. Our models predict that an intensive monitoring survey programme, such as Angstrom, which will be able to detect events of durations upwards of a day, could detect around 30 events per season within ∼5 arcmin of the M31 centre due to ordinary low-mass stars and remnants. This yield increases to more than 60 events for brown-dwarf dominated mass functions. The overall number of events and their average duration are sensitive diagnostics of the bulge mass, in particular the contribution of low-mass stars and brown dwarfs. The combination of an inclined disc, an offset bar-like bulge, and differences in the bulge and disc luminosity functions results in a four-way asymmetry in the number of events expected in each quadrant defined by the M31 disc axes. The asymmetry is sensitive to the bar prolongation, orientation and mass.</P>
High-precision photometry by telescope defocussing - VI. WASP-24, WASP-25 and WASP-26
Southworth, J.,Hinse, T. C.,Burgdorf, M.,Calchi Novati, S.,Dominik, M.,Galianni, P.,Gerner, T.,Giannini, E.,Gu, S.- H.,Hundertmark, M.,Jorgensen, U. G.,Juncher, D.,Kerins, E.,Mancini, L.,Rabus, M.,Ric Oxford University Press 2014 MONTHLY NOTICES- ROYAL ASTRONOMICAL SOCIETY Vol.444 No.1
Cahill Kerin M.,Gartia Manas R.,Sahu Sushant,Bergeron Sarah R.,Heffernan Linda M.,Paulsen Daniel B.,Penn Arthur L.,Noël Alexandra 한국독성학회 2022 Toxicological Research Vol.38 No.2
Approximately 7% of pregnant women in the United States use electronic-cigarette (e-cig) devices during pregnancy. There is, however, no scientific evidence to support e-cig use as being ‘safe’ during pregnancy. Little is known about the effects of fetal exposures to e-cig aerosols on lung alveologenesis. In the present study, we tested the hypothesis that in utero exposure to e-cig aerosol impairs lung alveologenesis and pulmonary function in neonates. Pregnant BALB/c mice were exposed 2 h a day for 20 consecutive days during gestation to either filtered air or cinnamon-flavored e-cig aerosol (36 mg/ mL of nicotine). Lung tissue was collected in offspring during lung alveologenesis on postnatal day (PND) 5 and PND11. Lung function was measured at PND11. Exposure to e-cig aerosol in utero led to a significant decrease in body weights at birth which was sustained through PND5. At PND5, in utero e-cig exposures dysregulated genes related to Wnt signaling and epigenetic modifications in both females (~ 120 genes) and males (40 genes). These alterations were accompanied by reduced lung fibrillar collagen content at PND5—a time point when collagen content is close to its peak to support alveoli formation. In utero exposure to e-cig aerosol also increased the Newtonian resistance of offspring at PND11, suggesting a narrowing of the conducting airways. At PND11, in females, transcriptomic dysregulation associated with epigenetic alterations was sustained (17 genes), while WNT signaling dysregulation was largely resolved (10 genes). In males, at PND11, the expression of only 4 genes associated with epigenetics was dysregulated, while 16 Wnt related-genes were altered. These data demonstrate that in utero exposures to cinnamon-flavored e-cig aerosols alter lung structure and function and induce sex-specific molecular signatures during lung alveologenesis in neonatal mice. This may reflect epigenetic programming affecting lung disease development later in life.