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- 저자 : Keisuke Abe (검색결과 19 건)
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Keisuke Masuda,Akira Furuyama,Kenji Ohsuga,Shota Abe,Hiroyoshi Kawaai The Korean Dental Society of Anesthsiology 2023 Journal of Dental Anesthesia and Pain Medicine Vol.23 No.3
Background: Recent animal studies have suggested the role of GABA type A (GABA-<sub>A</sub>) receptors in salivation, showing that GABA-<sub>A</sub> receptor agonists inhibit salivary secretion. This study aimed to evaluate the effects of propofol (a GABA-<sub>A</sub> agonist) on salivary secretions from the submandibular, sublingual, and labial glands during intravenous sedation in healthy volunteers. Methods: Twenty healthy male volunteers participated in the study. They received a loading dose of propofol 6 mg/kg/h for 10 min, followed by 3 mg/kg/h for 15 min. Salivary flow rates in the submandibular, sublingual, and labial glands were measured before, during, and after propofol infusion, and amylase activity was measured in the saliva from the submandibular and sublingual glands. Results: We found that the salivary flow rates in the submandibular, sublingual, and labial glands significantly decreased during intravenous sedation with propofol (P < 0.01). Similarly, amylase activity in the saliva from the submandibular and sublingual glands was significantly decreased (P < 0.01). Conclusion: It can be concluded that intravenous sedation with propofol decreases salivary secretion in the submandibular, sublingual, and labial glands via the GABA-<sub>A</sub> receptor. These results may be useful for dental treatment when desalivation is necessary.
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Keisuke Sugahara,Satoru Matsunaga,Masahito Yamamoto,Taku Noguchi,Sumiharu Morita,Masahide Koyachi,Yu Koyama,Takumi Koyama,Norio Kasahara,Shinichi Abe,Akira Katakura 대한해부학회 2020 Anatomy & Cell Biology Vol.53 No.4
Major bleeding associated with sagittal split ramus osteotomy (SSRO) involves vessels such as the inferior alveolar, facial, and maxillary arteries and veins, and the retromandibular vein (RMV). The present study aimed to clarify and classify the three-dimensional variations in RMV position and course direction in relation to the mandible. Specimens comprised a total of 15 scientific cadavers, and the relationship between RMV and the mandible lateral and posterior views was observed. We identified 3 patterns on the lateral view, the mean distance between the RMV and the posterior border of the ramus was 3.9 mm at the height of the lingula. A total of five course patterns were identified on the posterior view. In no course pattern, the RMV inferior to the lingula was lateral to its position superior to the lingual. The present findings suggest that it may be possible to predict correlations with intraoperative bleeding risk. Further study is planned using contrast computed tomography in patients with jaw deformity for skeletal classification.
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Risk factors for delayed healing at the free anterolateral thigh flap donor site
Abe, Yoshiro,Kashiwagi, Keisuke,Ishida, Soushi,Mineda, Kazuhide,Yamashita, Yutaro,Hashimoto, Ichiro Korean Society of Plastic and Reconstructive Surge 2018 Archives of Plastic Surgery Vol.45 No.1
Background The free anterolateral thigh (ALT) flap has been widely used for various kinds of reconstructions. However, delayed healing at the donor site occasionally occurs due to wound dehiscence or the partial loss of grafted skin at the donor site. The aim of the present study was to identify reliable predictive factors for delayed healing at the donor site after the harvest of a free ALT flap. Methods This study included 52 patients who underwent reconstructive procedures using free ALT flaps. The delayed healing group included patients with wounds at the donor site that had not healed over 3 weeks after surgery, and the normal healing group included patients who showed wound healing within 3 weeks after surgery. Multivariate logistic regression models were created to identify the risk factors for delayed healing at the ALT flap donor site. Results Among the 52 patients, 24 (46.2%) showed delayed healing at the donor site, and 6 patients required additional operative treatment. A high preoperative body mass index (BMI), smoking, and skin grafting were found to be significantly associated with delayed healing at the ALT donor site. Of the 37 patients who underwent skin grafting, 23 (62%) experienced delayed healing at the donor site. Conclusions A high preoperative BMI, smoking, and skin grafting were risk factors for delayed healing at the free ALT donor site. Skin grafting at the ALT donor site should be avoided in patients with a high BMI or a habit of smoking.
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Risk factors for delayed healing at the free anterolateral thigh flap donor site
Yoshiro Abe,Keisuke Kashiwagi,Soushi Ishida,Kazuhide Mineda,Yutaro Yamashita,Ichiro Hashimoto 대한성형외과학회 2018 Archives of Plastic Surgery Vol.45 No.1
Background The free anterolateral thigh (ALT) flap has been widely used for various kinds of reconstructions. However, delayed healing at the donor site occasionally occurs due to wound dehiscence or the partial loss of grafted skin at the donor site. The aim of the present study was to identify reliable predictive factors for delayed healing at the donor site after the harvest of a free ALT flap. Methods This study included 52 patients who underwent reconstructive procedures using free ALT flaps. The delayed healing group included patients with wounds at the donor site that had not healed over 3 weeks after surgery, and the normal healing group included patients who showed wound healing within 3 weeks after surgery. Multivariate logistic regression models were created to identify the risk factors for delayed healing at the ALT flap donor site. Results Among the 52 patients, 24 (46.2%) showed delayed healing at the donor site, and 6 patients required additional operative treatment. A high preoperative body mass index (BMI), smoking, and skin grafting were found to be significantly associated with delayed healing at the ALT donor site. Of the 37 patients who underwent skin grafting, 23 (62%) experienced delayed healing at the donor site. Conclusions A high preoperative BMI, smoking, and skin grafting were risk factors for delayed healing at the free ALT donor site. Skin grafting at the ALT donor site should be avoided in patients with a high BMI or a habit of smoking.
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Novel condylar repositioning method for 3D-printed models
Sugahara, Keisuke,Katsumi, Yoshiharu,Koyachi, Masahide,Koyama, Yu,Matsunaga, Satoru,Odaka, Kento,Abe, Shinichi,Takano, Masayuki,Katakura, Akira Korean Association of Maxillofacial Plastic and Re 2018 Maxillofacial Plastic Reconstructive Surgery Vol.40 No.-
Background: Along with the advances in technology of three-dimensional (3D) printer, it became a possible to make more precise patient-specific 3D model in the various fields including oral and maxillofacial surgery. When creating 3D models of the mandible and maxilla, it is easier to make a single unit with a fused temporomandibular joint, though this results in poor operability of the model. However, while models created with a separate mandible and maxilla have operability, it can be difficult to fully restore the position of the condylar after simulation. The purpose of this study is to introduce and asses the novel condylar repositioning method in 3D model preoperational simulation. Methods: Our novel condylar repositioning method is simple to apply two irregularities in 3D models. Three oral surgeons measured and evaluated one linear distance and two angles in 3D models. Results: This study included two patients who underwent sagittal split ramus osteotomy (SSRO) and two benign tumor patients who underwent segmental mandibulectomy and immediate reconstruction. For each SSRO case, the mandibular condyles were designed to be convex and the glenoid cavities were designed to be concave. For the benign tumor cases, the margins on the resection side, including the joint portions, were designed to be convex, and the resection margin was designed to be concave. The distance from the mandibular ramus to the tip of the maxillary canine, the angle created by joining the inferior edge of the orbit to the tip of the maxillary canine and the ramus, the angle created by the lines from the base of the mentum to the endpoint of the condyle, and the angle between the most lateral point of the condyle and the most medial point of the condyle were measured before and after simulations. Near-complete matches were observed for all items measured before and after model simulations of surgery in all jaw deformity and reconstruction cases. Conclusions: We demonstrated that 3D models manufactured using our method can be applied to simulations and fully restore the position of the condyle without the need for special devices.
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The influence of aroma on the work performance and mental state
Yudai Abe,Keisuke Suzuki,Kei Sato 대한인간공학회 2010 대한인간공학회 학술대회논문집 Vol.2010 No.5
In this research, the mechanism which an aroma gives to the improvement of the working efficiency under mental monotonous task was analyzed. Fluctuation of the cerebral blood flow and the fluctuation of electrocardiogram were observed when the test subject is working on mental task. The mental arithmetic of triple figures was set up as the mental task in this study. The peppermint aroma was supplied to the test subjects using a bubbling system when the working efficiency of the subject (mental-arithmetic speed) was delayed. Different density levels of aroma that the test subject likes and dislikes were set up. When the high density level of aroma which a subject does not like was supplied, the improvement of the task performance was not observed. But, when the aroma with the moderate density which a test subject likes was supplied, almost all subjects' working efficiency was improved. Awakening of the subjects in low arousal level, reduction of mental stress and increase of the amount of cerebral blood of the frontal region were observes by supplying aroma. It can be concluded that the preference level is also an important factor besides a medicinal effects to improve the work performance.
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Nobuyuki Hinata,Keisuke Hieda,Hiromasa Sasaki,Gen Murakami,Shinichi Abe,Akio Matsubara,Hideaki Miyake,Masato Fujisawa 대한해부학회 2014 Anatomy & Cell Biology Vol.47 No.1
Although the pelvic autonomic plexus may be considered a mixture of sympathetic and parasympathetic nerves, little information on its composite fibers is available. Using 10 donated elderly cadavers, we investigated in detail the topohistology of nerve fibers in the posterior part of the periprostatic region in males and the infero-anterior part of the paracolpium in females. Neuronal nitric oxide synthase (nNOS) and vasoactive intestinal polypeptide (VIP) were used as parasympathetic nerve markers, and tyrosine hydroxylase (TH) was used as a marker of sympathetic nerves. In the region examined, nNOS-positive nerves (containing nNOS-positive fibers) were consistently predominant numerically. All fibers positive for these markers appeared to be thin, unmyelinated fibers. Accordingly, the pelvic plexus branches were classified into 5 types: triple-positive mixed nerves (nNOS+, VIP+, TH+, thick myelinated fibers + or -); double-positive mixed nerves (nNOS+, VIP-, TH+, thick myelinated fibers + or -); nerves in arterial walls (nNOS-, VIP+, TH+, thick myelinated fibers-); non-parasympathetic nerves (nNOS-, VIP-, TH+, thick myelinated fibers + or -); (although rare) pure sensory nerve candidates (nNOS-, VIP-, TH-, thick myelinated fibers+). Triple-positive nerves were 5-6 times more numerous in the paracolpium than in the periprostatic region. Usually, the parasympathetic nerve fibers did not occupy a specific site in a nerve, and were intermingled with sympathetic fibers. This morphology might be the result of an "incidentally" adopted nerve fiber route, rather than a targetspecific pathway.
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Enhanced Regular Expression as a DGL for Generation of Synthetic Big Data
Kai Cheng,Keisuke Abe 한국정보처리학회 2023 Journal of information processing systems Vol.19 No.1
Synthetic data generation is generally used in performance evaluation and function tests in data-intensiveapplications, as well as in various areas of data analytics, such as privacy-preserving data publishing (PPDP)and statistical disclosure limit/control. A significant amount of research has been conducted on tools andlanguages for data generation. However, existing tools and languages have been developed for specificpurposes and are unsuitable for other domains. In this article, we propose a regular expression-based datageneration language (DGL) for flexible big data generation. To achieve a general-purpose and powerful DGL,we enhanced the standard regular expressions to support the data domain, type/format inference, sequence andrandom generation, probability distributions, and resource reference. To efficiently implement the proposedlanguage, we propose caching techniques for both the intermediate and database queries. We evaluated theproposed improvement experimentally.
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