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Buckling analysis of nanoplate-type temperature-dependent heterogeneous materials
Karami, Behrouz,Karami, Sara Techno-Press 2019 Advances in nano research Vol.7 No.1
This paper develops a four-unknown refined plate theory and the Galerkin method to investigate the size-dependent stability behavior of functionally graded material (FGM) under the thermal environment and the FGM having temperature-dependent material properties. In the current study two scale coefficients are considered to examine buckling behavior much accurately. Reuss micromechanical scheme is utilized to estimate the material properties of inhomogeneous nano-size plates. Governing differential equations, classical and non-classical boundary conditions are obtained by utilizing Hamiltonian principles. The results showed the high importance of considering temperature-dependent material properties for buckling analysis. Different influencing parametric on the buckling is studied which may help in design guidelines of such complex structures.
SARS-CoV-2 in brief: from virus to prevention
Hassan Karami,Zeinab Karimi,Negin Karami 질병관리본부 2022 Osong Public Health and Research Persptectives Vol.13 No.6
The recent outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a highly transmissible virus with a likely animal origin, has posed major and unprecedented challenges to millions of lives across the affected nations of the world. This outbreak first occurred in China, and despite massive regional and global attempts shortly thereafter, it spread to other countries and caused millions of deaths worldwide. This review presents key information about the characteristics of SARS-CoV-2 and its associated disease (namely, coronavirus disease 2019) and briefly discusses the origin of the virus. Herein, we also briefly summarize the strategies used against viral spread and transmission.
Sensitivity analysis of numerical schemes in natural cooling flows for low power research reactors
Karami, Imaneh,Aghaie, Mahdi Techno-Press 2017 Advances in energy research Vol.5 No.3
The advantages of using natural circulation (NC) as a cooling system, has prompted the worldwide development to investigate this phenomenon more than before. The interesting application of the NC in low power experimental facilities and research reactors, highlights the obligation of study in these laminar flows. The inherent oscillations of NC between hot source and cold sink in low Grashof numbers necessitates stability analysis of cooling flow with experimental or numerical schemes. For this type of analysis, numerical methods could be implemented to desired mass, momentum and energy equations as an efficient instrument for predicting the behavior of the flow field. In this work, using the explicit, implicit and Crank-Nicolson methods, the fluid flow parameters in a natural circulation experimental test loop are obtained and the sensitivity of solving approaches are discussed. In this way, at first, the steady state and transient results from explicit are obtained and compared with experimental data. The implicit and crank-Nicolson scheme is investigated in next steps and in subsequent this research is focused on the numerical aspects of instability prediction for these schemes. In the following, the assessment of the flow behavior with coarse and fine mesh sizes and time-steps has been reported and the numerical schemes convergence are compared. For more detail research, the natural circulation of fluid was modeled by ANSYS-CFX software and results for the experimental loop are shown. Finally, the stability map for rectangular closed loop was obtained with employing the Nyquist criterion.
Radial Basis Function Neural Network for Power System Transient Energy Margin Estimation
Karami, Ali The Korean Institute of Electrical Engineers 2008 Journal of Electrical Engineering & Technology Vol.3 No.4
This paper presents a method for estimating the transient stability status of the power system using radial basis function(RBF) neural network with a fast hybrid training approach. A normalized transient energy margin(${\Delta}V_n$) has been obtained by the potential energy boundary surface(PEBS) method along with a time-domain simulation technique, and is used as an output of the RBF neural network. The RBF neural network is then trained to map the operating conditions of the power system to the ${\Delta}V_n$, which provides a measure of the transient stability of the power system. The proposed approach has been successfully applied to the 10-machine 39-bus New England test system, and the results are given.
FIXED POINT RESULTS ON S-METRIC SPACE VIA SIMULATION FUNCTIONS
Karami Abdullah,Sedghi Shaban,Shobe Nabi,Hyun H.G. 경남대학교 기초과학연구소 2019 Nonlinear Functional Analysis and Applications Vol.24 No.4
In this paper, we prove some common xed point theorems for two mappings satisfying generalized contractive condition in S-metric spaces via simulation functions. Our results extend and improve several previous well-known works.
Karami, Bahador,Akrami, Sedigheh,Khodabakhshi, Saeed Korean Chemical Society 2013 Bulletin of the Korean Chemical Society Vol.34 No.12
Novel tri- and tetra-substituted pyrimido[4,5-d]pyridazines-2(1H,3H,7H)-ones have been synthesized via the regiospecific condensation reaction of hydrazine derivatives with 5-acetyl-4-aryloyl-6-methyl-3,4-dihydropyrimidinones in the presence of $SiO_2-Y(NO_3)_3$ as a green and recyclable catalyst under solvent-free conditions. All products were obtained in high yields and short reaction time. Employing this method is in accord with green chemistry principles.
Karami, Esmaeil,Alishahi, Mojtaba,Molayemraftar, Taravat,Ghorbanpour, Masoud,Tabandeh, Mohammad Reza,Mohammadian, Takavar The Korean Society of Fisheries and Aquatic Scienc 2019 Fisheries and Aquatic Sciences Vol.22 No.10
Background: Lactococcus garvieae is one of the most important risk factors in the rainbow trout culture. Therefore, the purpose of this study was to identify and detect strains isolated from rainbow trout suspected of having Lactococcus garvieae using biochemical characteristics and PCR and determination of the degree of severity of isolated strains. Methods: In this study, the cause of lactococcosis in selected rainbow trout farms in Kohkilooieh and Boyerahmad province was assayed. Gram-positive and catalase-negative bacterial isolates were first obtained from selected trout fish farms using conventional biochemical tests and PCR assay. The 10-day LD<sub>50</sub> method (concentration causing 50% mortality in 10 days) was used to determine the severity of the isolated bacteria. Results: One bacterial isolate was detected from all sampled fish which confirmed as Lactococcus garvieae using a specific PCR assay based on the 16S rDNA gene by producing a single band of 1107 bp. Analysis of the rate of mortality showed that the 10-day LD<sub>50</sub> was 4.6 × 10<sup>5</sup> CFU/fish. The results of this study showed that isolated bacteria had high severity for rainbow trout. The presence of bacteria in internal organs of suspected fish showed a severe systemic infection in challenged fish. Antibiogram assay also indicated that the isolated Lactococcus garvieae were resistant to some mostly used antibiotics in rainbow trout. Conclusions: According to current research, it can be concluded that the condition of lactococcosis in the studied area is not suitable, and despite the presence of disease, there is no proper action to control and prevent the disease. Unfortunately, isolated bacteria from the studied area have a very high severity compared to bacteria isolated from other regions of the country or other countries. Therefore, further investigation is needed to determine the cause of this difference and possibly in the design of the vaccine.
Karami, Hadi,Baradaran, Behzad,Esfehani, Ali,Sakhinia, Masoud,Sakhinia, Ebrahim Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2
Background: Acute myeloid leukemia (AML) is a fatal hematological malignancy which is resistant to a variety of chemotherapy drugs. Myeloid cell leukemia-1 (Mcl-1), a death-inhibiting protein that regulates apoptosis, has been shown to be overexpressed in numerous malignancies. In addition, it has been demonstrated that the expression level of the Mcl-1 gene increases at the time of leukemic relapse following chemotherapy. The aim of this study was to target Mcl-1 by small interference RNA (siRNA) and analyze its effects on survival and chemosensitivity of acute myeloid leukemia cell line HL-60. Materials and Methods: siRNA transfection was performed with a liposome approach. The expression levels of mRNA and protein were measured by real-time quantitative PCR and Western blot analysis, respectively. Trypan blue assays were performed to evaluate tumor cell growth after siRNA transfection. The cytotoxic effects of Mcl-1 siRNA (siMcl-1) and etoposide were determined using MTT assay on their own and in combination. Apoptosis was quantified using a DNA-histone ELISA assay. Results: Transfection with siMcl-1 significantly suppressed the expression of Mcl-1 mRNA and protein in a time-dependent manner, resulting in strong growth inhibition and spontaneous apoptosis. Surprisingly, pretreatment with siMcl-1 synergistically enhanced the cytotoxic effect of etoposide. Furthermore, Mcl-1 down-regulation significantly increased apoptosis sensitivity to etoposide. No significant biological effects were observed with negative control siRNA treatment. Conclusions: Our results suggest that specific suppression of Mcl-1 by siRNA can effectively induce apoptosis and overcome chemoresistance of leukemic cells. Therefore, siMcl-1 may be a potent adjuvant in leukemia chemotherapy.