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      • KCI등재

        Perception of Child Abuse and Child Disciplinary Practice among Adults Abused as Children

        Ka Young Moon,So Young Irene Lee,A Reum Lee,Ka Yeong An,Kyung Soo Jung,Kyoung-Il Paek,Hyun Ah Kang,Ji Young Kang,Shun Ah Chung 대한소아청소년정신의학회 2019 소아청소년정신의학 Vol.30 No.2

        Objectives: The aim of this study was to compare differences in perception and knowledge of child abuse and child disciplinary practices according to the history of child abuse victimization. Methods: A questionnaire survey on child abuse was conducted with 491 adults raising children. We compared the perception and knowledge of child abuse and child disciplinary practices between two groups of adults with and without a history of childhood abuse victimization. Results: The group with a history of childhood abuse had lower levels of knowledge of child abuse (F=6.990, p<0.01) and engaged in more negative disciplinary practices (F=5.974, p<0.05) than those without. However, no differences in the perception of child abuse were observed between the two groups. Conclusion: The results suggest that adults with a history of childhood abuse have lower levels of knowledge of child abuse and use more negative disciplinary practices in raising their children. This highlights the need to administer not only educational but also more direct hands-on interventions to vulnerable parents in order to foster healthy parenting and disciplinary practices.

      • 치아의 치수 줄기 세포와 치주 인대 줄기 세포의 석회화와 분화에 PRP가 미치는 영향

        Ka-young Lee,Ji-young Park,Sang-won Moon,Jong-Tae Park,Dong-seol Lee,Heung-Joong Kim,JOO-CHEOL PARK 대한구강해부학회 2007 대한구강해부학회지 Vol.31 No.1

        1 . INTRODUCTION Tissue engineering using stem cell has been studied extensively in attempt to regenerate the lost tooth ancVor damaged periodontal tissue. Although Platelet rich plasma(PRP) isolated from the blood has been applied to the implant surgery, the studies about the direct role of the PRP on the cell are not sufficient. To use PRP in clinic successfully, evaluation about effect of PRP on the cytological lev하 is req버red. n‘ PURPOSE The purpose of this study was to investigate the roles of PRP during the differentiation of dental pulp stem ceJls (DPSCs) and periodontal ligament stem cells (PDLSCs) at cytol맹ic and histologic level. Ill. MATERIALS AND METHOD 1. Cell isolation & primary c띠ture Dental p비,p cells and periodontal ligament cells were isolated from the exf,미 iated third molar of human who dose not have any systernic disease, respectively. The cells were divided into two groups ; PRP was added in one group experimental and was not added in the other group as a control. And the cells were cultured for 15 days. 2. PRP preparation. After taking blood from the 5 rats (male, 6 weeks old), PRP was isolated from the blood with thrombin by the centrifugation method. 3. Immunofluorescence Axioscope multi fluorescence rnicroscopic observation was performed using STRO-1 antibody which is mesenchymal stem ceJl marker to iden디 fy the stem cells in the culture 4. Alizarin-Red S staining At the time of 0, 5, 10 때d 15 days after the cell culture, the Alizarin Red-S stai미 ng was performed to evaluate the rruner때alization. 5. RT-PCR Analysis At the time of 0, 5, 10 없d 15 days after the cell c비ture, total RNA was isolated using Trizol reagent and the first strand cDNA was synthesized. And PCR was performed with the specific primers of DSPP, BSP, ALP, type 1 collagen, osteocalcin, osteonectin and GAPDH to evaluate the differentiation. IV. RESULT 1. Analysis of Immunofluorescence Sever외 stem cells specific to STRO-1 antibody were observed through the FITC in DPSC and PDLSC. 2. Analysis of Alizarin Red-S staining No rnineralization was obseπed before the cultur어 15 days in both control-DPSC group and PRP-DPSCs group. However, at the c띠tured 15 days, mineralization was obseπed in the PRP-PDLSCs group. 3. RT-PCR 1) In PRP-DPSCs group, expression of DSPP were increased compared to those of control group‘ 2) In PRP-PDLSCs group, expression of DSPP, ALP, osteocalcin were almost same cornpared to those of control group V. Conclusion The result may suggests the functional role of PRP in the differentiation 뻐d mineralization of DPSCs by the increase of DSPP.

      • KCI우수등재

        원저 : 과체중과 비만 초등학생 부모들의 자녀 체중조절 행태

        전영배 ( Young Bae June ),이가영 ( Ka Young Lee ),박태진 ( Tae Jean Park ),하성자 ( Sung Ja Ha ),손영우 ( Young Woo Son ),김빛나,( Hye Jeong Moon ) 대한비만학회 2006 The Korean journal of obesity Vol.15 No.1

        연구배경: 초등학생 시기는 성인 비만으로 지속할 위험이 증가하는 청소년 비만을 예방하기 위해 중요한 시기이다. 이러한 면에서 과체중 또는 비만 초등학생들의 부모들을 대상으로 자녀의 체중과 관련된 문제에 대한 인식도와 자녀의 체중조절 행태를 알아보고자 하였다. 방법: 2003년 5월 김해시 3개 초등학교 1~5학년 학생 가운데 학교 신체검진에서 과체중 또는 비만으로 파악된 초등학생들 397명과 학부모들이 연구 대상이었다. 자녀들의 체중 상태는 체질량지수 기준표 (1999년)를 사용하여 과체중과 비만으로 구분하였다. 부모의 체중과 관련된 문제에 관한 인식도와 자녀의 체중 조절 행태를 설문지로 조사하였다. 결과: 과체중 또는 비만 아동의 84%가 1년 전에도 과체중 또는 비만이었다. 93%의 부모들이 자녀의 체중을 과다하다고 인식하였고, 82%의 부모들이 자녀의 체중이 외모에 문제가 되며, 78%에서 체중이 건강에 문제가 된다고 인식하였다. 57%의 부모들이 자녀의 체중 조절을 시도한 적이 있다고 응답하였고, 조절 방법은 운동 (40%), 식사조절 (35%), 학교프로그램 (9%) 순서이었다. 자녀의 체중을 조절한 가장 흔한 이유는 `성인비만으로 지속할 가능성 때문` 이었고 (77%, 173/226명), 체중을 조절하지 않은 가장 흔한 이유는 `성장하면서 체중조절이 될 것이기 때문`이었다 (51%, 87/171명). 결론: 과체중 또는 비만 아동의 부모들은 과체중 또는 비만과 관련된 문제에 대하여 심각하게 인지하고 있음에도 성장에 따른 체중 감량을 기대하고 있었다. 비만 아동들에서 체중에 대한 관리 없이 성장하면서 체중이 저절로 감소하기가 어려움을 알려주어야 할 것이다. Background: The preadolescencence is an important period to prevent adolescent obesity because of a higher risk of being obese adults in adolescents. Therefore, the purpose of our study was to examine parental perception of their child`s weight-related problems, and parental control over their child`s weight among elementary school children being overweight or obese. Methods: 397 elementary school children being overweight or obese and their parents were enrolled for the study in May, 2003 from three elementary schools in Kimhae. The body mass index (BMI) of children were calculated using their measured height and weight. Definition of children`s overweight or obesity were based on the age and gender-specific Korea children`s BMI standards (1999). The parental perception of their child`s weight status and weight-related problems, and parental control over their child`s weight were surveyed using a questionnaire. Results: 84% of children being overweight or obese were overweight or obese in the last year. 93% of parents perceived their child`s weight as overweight, and 82% and 78% of them replied their child`s weight caused appearance problems and health problems, respectively. 57% of parents tried to control their child`s weight and they used exercise (40%), diet (35%), and school program for weight losing methods. The most frequent reason of why parents controlled over their child`s weight was `worry about becoming obese adult` (77%, n = 173/226). In contrast, the most frequent reason of why parents did not control over their child`s weight was `expectation of spontaneous weight loss with growth` (51%, n = 87/171). Conclusion: Although parents of children being overweight or obese significantly concerned about their child`s weight status and weight-related problems, many of them expected their child`s weight would be lost with growth. They should have informed about the difficulty of spontaneous weight loss among children being overweight or obese.

      • Diallel Cross Analysis Among Three Different Types of Corn: Supersweet, Waxy and Field Corn in Korea and China

        Ka-Hee Moon,Soon-Kwon Kim,Ji-Young Yoon,Don-Ho Gang,Win Win Nwe,Chang-Suk Huh 한국작물학회 2010 한국작물학회 학술발표대회 논문집 Vol.2010 No.04

        We studied on the diallel cross analysis of three different types of corn(Zea mays L.); supersweet(ss), sticky waxy and normal field corn in Korea and China. Four inbred lines each of three different types were crossed in a full diallel. Testing of 66 F1 crosses were made at two locations in Korea and China, respectively, in 2009. The objectives of the experiment was first to study different levels of heterosis among three types. In Korea, average ear length of 16 F1 crosses was the longest in N x wx (197mm), followed by wx x ss (193mm) and N x ss (191mm). Average of ss, wx and N were 135mm, 171 mm and 155mm. The relatively high level of N might be location specific breeding results, where the testing was done at the center of waxy corn breeding. Trends of three F1 crosses in China were similar with normal and supersweet corn. The result of this study has supported for breeding of high quality sticky-supersweet and high yield potential of normal -supersweet corn hybrids in the developing world to provide nutrition, sugar and other minerals such as Vitamin A and anthocyanin, simultaneously as a high quality food.

      • Associations between thyroid hormone levels and regional fat accumulation in euthyroid men

        Moon, Min Kyong,Hong, Eun Shil,Lim, Jung Ah,Cho, Sun Wook,Soo, Lim,Choi, Sung Hee,Yi, Ka Hee,Park, Do Joon,Park, Young Joo,Jang, Hak Chul European Federation of Endocrine Societies 2013 European journal of endocrinology Vol.168 No.6

        <P><B>Objective</B></P><P>Body adiposity, especially ectopic fat accumulation, has a range of metabolic and cardiovascular effects. This study aimed to investigate whether thyroid function is associated with various regional fat quantities in euthyroid subjects.</P><P><B>Methods</B></P><P>A total of 100 euthyroid men (free triiodothyronine (fT<SUB>3</SUB>), 4.77±1.21 pg/ml; free thyroxine (fT<SUB>4</SUB>), 1.38±0.21 ng/dl; and TSH, 2.09±0.91 μIU/ml) were enrolled in this cross-sectional study. We measured accumulated regional fat using 64-slice multi-detector computed tomography. Multiple linear regression analysis was used to determine whether accumulated fat in each region was associated with clinical parameters after adjusting for age.</P><P><B>Results</B></P><P>FT<SUB>3</SUB> was inversely correlated with BMI (<I>r</I>=−0.232, <I>P</I>=0.029) and LDL cholesterol level (<I>r</I>=−0.277, <I>P</I>=0.019). FT<SUB>4</SUB> was inversely correlated with waist circumference (<I>r</I>=−0.350, <I>P</I>=0.008) and BMI (<I>r</I>=−0.355, <I>P</I><0.001). In multiple linear regression analysis, fT<SUB>3</SUB> and fT<SUB>4</SUB> levels were significantly associated with pericardial fat volume (fT<SUB>3</SUB>: <I>B</I>=−0.079, 95% CI −0.142 to −0.017, <I>P</I>=0.013; fT<SUB>4</SUB>: <I>B</I>=−0.411, 95% CI −0.780 to −0.042, <I>P</I>=0.030) in euthyroid men, independent of age. FT<SUB>3</SUB> level was inversely associated with intramuscular fat area (<I>B</I>=−0.059, 95% CI −0.106 to −0.011, <I>P</I>=0.016) and hepatic fat quantity (<I>B</I>=−0.237, 95% CI −0.441 to −0.033, <I>P</I>=0.024) in euthyroid men, independent of age.</P><P><B>Conclusions</B></P><P>In euthyroid men, low levels of fT<SUB>3</SUB> and fT<SUB>4</SUB> were significantly associated with increased pericardial fat volume and BMI.</P>

      • Thyroglobulin in Washout Fluid From Lymph Node Fine-needle Aspiration Biopsy in Papillary Thyroid Cancer: Large-scale Validation of the Cutoff Value to Determine Malignancy and Evaluation of Discrepant Results

        Moon, Jae Hoon,Kim, Yong Il,Lim, Jung Ah,Choi, Hoon Sung,Cho, Sun Wook,Kim, Kyung Won,Park, Hyo Jin,Paeng, Jin Chul,Park, Young Joo,Yi, Ka Hee,Park, Do Joon,Kim, Sang Eun,Chung, June-Key The Endocrine Society 2013 The Journal of clinical endocrinology & metabolism Vol.98 No.3

        <P><B>Context:</B></P><P>There are still some controversies regarding the cutoff value and the influential factors of thyroglobulin (Tg) concentration in washout fluid from fine-needle aspiration (FNA) biopsy (FNA-Tg) on cervical lymph nodes (LNs) in patients with papillary thyroid cancer (PTC).</P><P><B>Objective:</B></P><P>Our aims were to validate the cutoff value of FNA-Tg in diagnosing malignant LNs on a large scale and to investigate the influential factors that could result in the discrepancy between the final diagnosis and FNA-Tg.</P><P><B>Design, Setting, and Participants:</B></P><P>We conducted a retrospective cohort study based on hospital records with 528 cases of FNA-Tg measurement from 419 PTC patients.</P><P><B>Main Outcome Measure:</B></P><P>The cutoff value of FNA-Tg was obtained from receiver operating characteristic analysis with final diagnosis. Binary logistic regression analysis was performed to investigate the influential factors.</P><P><B>Results:</B></P><P>In the final diagnosis, 190 LNs were malignant, and 338 LNs were benign. The median FNA-Tg was 521.2 (3676.8) ng/mL in malignant LNs, and 0.1 (0.2) ng/mL in benign LNs. The optimal cutoff value of FNA-Tg in distinguishing malignant LNs from benign LNs was 1.0 ng/mL (sensitivity, 93.2%; specificity, 95.9%) in all cases. Combining FNA-Tg and FNA cytology showed superior diagnostic power (sensitivity, 98.4%; specificity, 94.4%) when compared with diagnostic strategy using either FNA cytology or FNA-Tg alone. FNA-Tg, serum TSH, and serum Tg were higher in nonthyroidectomized patients than in thyroidectomized patients (<I>P</I> < .001, respectively). FNA-Tg was correlated with serum TSH and Tg levels (<I>P</I> < .001, respectively), and binary logistic regression analysis showed that serum TSH suppression and serum Tg presence independently affected the diagnosis made by FNA-Tg.</P><P><B>Conclusions:</B></P><P>Our results validated 1.0 ng/mL of FNA-Tg as a cutoff value for diagnosing LN metastasis of PTC and suggested that serum TSH suppression and serum Tg presence should be considered in diagnosing LN malignancy with FNA-Tg in PTC patients.</P>

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