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Predicting the next turn at road junction from big traffic data
Zhuang, Y.,Fong, S.,Yuan, M.,Sung, Y.,Cho, K.,Wong, R. K. Kluwer Academic Publishers 2017 The Journal of supercomputing Vol.73 No.7
<P>Smart city is an emerging research field nowadays, with emphasis of using big data to enhance citizens' quality of life. One of the prevalent smart city projects is to use big traffic data collected from road users over time, for road planning, traffic light scheduling, traffic jam relief, and public security. In particular, being able to know a road user's current location and predict his/her next move is important in today's intelligent transportation systems. Trajectory prediction has become a prudential research study direction, by which many algorithms have been published before. In this paper, we present a simple probabilistic model which predicts road users' next locations based on the 'concept of segments' abstracted from historical trails which the users have taken and accumulated over time in some data archive. Given a trajectory and a current location, the road user's next move in terms of road direction can be predicted at the junction. It is found that each road user would have his/her unique travel pattern hidden in the aggregate big traffic data. These patterns could be modeled from connected segments for simplicity. With the longer the trail and more frequently this trail was travelled, the more accurate that the next turn can be predicted. Simulation experiment was conducted based on summing up the segments from empirical trajectory data that was used in trajectory data mining by Microsoft. The results of our alternative model in contrast to the state of the arts demonstrated good efficacy.</P>
Tang, W.K.,Wong, K.B.,Lam, Y.M.,Cha, S.S.,Cheng, C.H.K.,Fong, W.P. North-Holland Pub ; Elsevier Science Ltd 2008 FEBS letters Vol.582 No.20
The crystal structure of seabream antiquitin in complex with the cofactor NAD<SUP>+</SUP> was solved at 2.8A resolution. The mouth of the substrate-binding pocket is guarded by two conserved residues, Glu120 and Arg300. To test the role of these two residues, we have prepared the two mutants E120A and R300A. Our model and kinetics data suggest that antiquitin's specificity towards the substrate α-aminoadipic semialdehyde is contributed mainly by Glu120 which interacts with the α-amino group of the substrate. On the other hand, Arg300 does not have any specific interaction with the α-carboxylate group of the substrate, but is important in maintaining the active site conformation.
Hoover-Fong, J.,Sobreira, N.,Jurgens, J.,Modaff, P.,Blout, C.,Moser, A.,Kim, O.H.,Cho, T.J.,Cho, S.,Kim, S.,Jin, D.K.,Kitoh, H.,Park, W.Y.,Ling, H.,Hetrick, Kurt N.,Doheny, Kimberly F.,Valle, D.,Pauli University of Chicago Press [etc.] 2014 American journal of human genetics Vol.94 No.1
Spondylometaphyseal dysplasias (SMD) constitute a rare group of bone disorders. Two members of the SMD group have distinctive ophthalmologic manifestations: SMD with cone-rod dystrophy (SMD-CRD; MIM 608940) and axial SMD with retinal degeneration (MIM 602271). Additional features of SMD-CRD include rhizomelia, lower extremity bowing, evolving anterior vertebral protrusions, metaphyseal cupping, and progressive visual impairment with pigmentary maculopathy and electroretinographic evidence of cone-rod dysfunction. Affected siblings have been described, thus suggesting autosomal recessive inheritance. Here eight individuals from 6 unrelated families with SMD-CRD were submitted to the Baylor-Hopkins Center for Mendelian Genomics (BHCMG). Patients 1, 2, 4-6 (Walters et al, 2004) and 7 (Kitoh et al, 2011) were described previously. Patient 8 has not reached final adult height, but is short for his age (Z=-7.6) with lower extremity bowing and diagnosis of retinal dystrophy affecting both cones and rods made at age 45 months. Using WES and targeted Sanger sequencing, we found 8 rare PCYT1A variants (1 nonsense, 1 frame shifting indel, and 6 missense variants) present either in the homozygous or compound heterozygous state in all 8 individuals. PCYT1A encodes the alpha isoform of an enzyme known as CTP (phosphocholine cytidylytransferase), essential for phosphotidylcholine synthesis. Mutations in genes involved in fatty acid metabolism have been implicated in other dysplasias (e.g. RCDP and Conradi-Hunermann), as well as retinal disease where there are deficient or abnormal fatty acids (e.g. eicosapentanoic and docosahexanoic acid). Further examination of phospholipid metabolism may lead to the genetic etiology of other SMDs, particularly those with ocular manifestations.
Design of hand gesture interaction framework on clouds for multiple users
Kim, Y.,Cho, S.,Fong, S.,Park, Y. W.,Cho, K. Springer Science + Business Media 2017 The Journal of supercomputing Vol.73 No.7
<P>To develop cooperative content based on the hand gestures of multiple users, typical frameworks must be separately used for the communication among computers and hand gesture recognition. In this paper, we propose a framework that enables users who are far apart to interact using hand gestures in the same virtual environment. This approach makes possible remote cooperative education content. We present the design of a server and client, as well as techniques for respectively managing multiple users, controlling crashes among multiple users, and managing gesture data for activating the proposed framework on clouds. To verify that the framework enables multiple users to interact, we developed a virtual chemical experiment based on the proposed design and performed the simulation with it. The framework can be used for a variety of educational content using interactions among multiple users.</P>
Factors influencing school connectedness: Chinese adolescents' perspectives
Mantak Yuen,Patrick S. Y. Lau,Queenie A. Y. Lee,Norman C. Gysbers,Raymond M. C. Chan,Ricci W. Fong,Y. B. Chung,Peter M. K. Shea 서울대학교 교육연구소 2012 Asia Pacific Education Review Vol.13 No.1
This study explored the concept of school connectedness and the factors that may influence its development with a sample of Chinese adolescents. Six focus groups involving 52 high school students were conducted using a set of predetermined discussion topics. Results indicated that the students fully understood the notion of school connectedness and could identify a number of key influences affecting its development. These factors could be grouped under several domains including teacher care, peer relations, broader school relationships, school disciplinary policies and practices, activities within the school's guidance and counseling program, and opportunities for talent development. The students were also able to suggest practical strategies that schools might introduce to enhance and strengthen students' acquisition of connectedness to school. The implications from the findings are discussed with particular reference to implementing comprehensive school guidance and counseling program in Hong Kong.
To, J. W.,Ng, J. W.,Siahrostami, S.,Koh, A. L.,Lee, Y.,Chen, Z.,Fong, K. D.,Chen, S.,He, J.,Bae, W. G. Springer Science + Business Media 2017 NANO RESEARCH Vol.10 No.4
<P>The development of high-performance and low-cost oxygen reduction and evolution catalysts that can be easily integrated into existing devices is crucial for the wide deployment of energy storage systems that utilize O-2-H2O chemistries, such as regenerative fuel cells and metal-air batteries. Herein, we report an NH3-activated N-doped hierarchical carbon (NHC) catalyst synthesized via a scalable route, and demonstrate its device integration. The NHC catalyst exhibited good performance for both the oxygen reduction reaction (ORR) and the oxygen evolution reaction (OER), as demonstrated by means of electrochemical studies and evaluation when integrated into the oxygen electrode of a regenerative fuel cell. The activities observed for both the ORR and the OER were comparable to those achieved by state-of-the-art Pt and Ir catalysts in alkaline environments. We have further identified the critical role of carbon defects as active sites for electrochemical activity through density functional theory calculations and high-resolution TEM visualization. This work highlights the potential of NHC to replace commercial precious metals in regenerative fuel cells and possibly metal-air batteries for cost-effective storage of intermittent renewable energy.</P>