Case Report : Hepatoid Carcinoma of the Pancreas Combined with Neuroendocrine Carcinoma

( Ji Ye Jung ),( Yoon Jae Kim ),( Hee Man Kim ),( Hong Jeoung Kim ),( Seung Woo Park ),( Si Young Song ),( Jae Bock Chung ),( Chang Moo Kang ),( Joo Yeon Pyo ),( Woo Ick Yang ),( Seung Min Bang ) The Editorial Office of Gut and Liver 2010 Gut and Liver Vol.4 No.1

Hepatoid carcinoma is a primary extrahepatic carcinoma whose morphology, immunohistochemistry, and behavior are similar to those of hepatocellular carcinoma. The most common sites of extrahepatic carcinoma are the stomach and ovary, but nine cases of hepatocellular differentiation of the pancreas have been reported in the literature. We report another case of hepatoid carcinoma of the pancreas that was associated with the development of a pancreatic endocrine carcinoma in a 46-year-old man. Serum alpha-fetoprotein (AFP) was elevated to 262.49 IU/mL and radiological examinations revealed a mass measuring 7.5 cm in diameter in the head of the pancreas. He underwent a conventional Whipple operation, and light microscopy showed adenocarcinoma that was immunopositive for AFP, hepatocyte antigen, cytokeratin, chromogranin, synaptophysin, and alpha-1 antichymotrypsin. Although hepatoid differentiation was not shown unequivocally histologically, other immunohistochemistry findings supported the diagnosis of hepatoid carcinoma combined with neuroendocrine carcinoma. The patient was healthy and had no evidence of recurrence at 4 months after the surgery. This report describes why hepatoid carcinoma should be considered as a differential diagnosis of a pancreatic mass, especially when serum AFP is elevated. (Gut Liver 2010;4:98-102)

기관지석으로 발현한 기관지성 방선균증 1예

정숙인,천정학,홍종락,고영민,정만표,권오정,이종헌,백경란,송재훈 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2

기관지성 방선균증은 매우 예외적이고 드물며 임상양상이 다양하여 폐암과의 감별이 어렵기도 하지만 기관지내시경 검사를 통해 진단할 수 있고 항생제 투여로 완치될 수 있는 질환이다. 저자들은 기관지석과 함께 발현한 기관지성 방선균증을 장기간의 경구 항생제 요법으로 완치한 1례를 경험하였기에 보고하는 바이다. Endobronchial actmomycosis is considered as an exceptional event. We report a case of a 49-year-old woman who presented with cough and exertional dyspnea for 20 months. Her chest X-ray showed calcified lymph nodes in the right lower paratracheal and subcarinal area and consolidation in the right middle lobe. Bronchoscopic examination demonstrated whitish broncholithiasis with mucosal nodularity in the bronchus intermedius obstructing the lumen near-completely. The biopsy specimen revealed sulfur granules and calcified material which were consistent with actmomycosis. Prolonged oral antibiotic treatment resulted in complete recovery, without need for surgical resection.

편측안면경련 환자에서의 임상적 중증도를 평가하기 위한 전기생리학적 연구

전성만,김종국,정재익,차재관,김상호,김재우 대한신경과학회 1998 대한신경과학회지 Vol.16 No.2

충북지역 농촌주민의 춘계영양섭취에 관한 조사

박정섭,정만재,김교창 忠北大學校 새마을硏究所 1982 새마을 硏究 論文集 Vol.1 No.-

본문참고

AWS ER70S-6, 1.2mm 솔리드 와이어를 사용하는 가스금속아크용접(Gas Metal Arc Welding)에서 작업자의 용접흄 및 금속 폭로에 영향을 주는 요인

정재열,김정만,김용규 동아대학교 부설 산업의학연구소 1997 산업의학연구소 논총 Vol.- No.3

CO₂용접을 대상으로 용접자세, 용접전류 및 헬멧에서 아크까지의 거리 등에 따라서 작업장에서 발생하는 용접흄과 금속에 대한 폭로농도를 파악하여 폭로에 영향을 줄 수 있는 요인을 밝히고자 본 연구를 수행하였다. 중장비 제조업체에서 직경 1.2mm 솔리드 와이어(AWS ER70S-6, BS A18, JIS YGW12)만을 이용하여 CO₂용접을 하는 작업자 95명(전자세 작업자 34명, 아래보기와 수평자세 30명, 위보기와 수직자세 31명)을 대상으로 수행하였다. 연구결과를 요약하면 다음과 같다. 1. 아래보기와 수평자세에서 용접흄의 폭로농도는 15.83mg/㎥으로 가장 높았고, 용접전류도 257.83암페어로 가장 높았으며 헬멧에서 아크까지의 거리 또한 44.87cm으로 가장 멀었다. 2. 철, 망간, 구리, 아연의 금속 폭로농도는 아래보기와 수평자세에서 각각 5.254mg/㎥, 0.849mg/㎥, 0.072mg/㎥, 0.048mg/㎥으로 가장 높았다. 용접흄의 폭로농도가 높을 수록 용접 와이어 그리고 일부 금속은 모재에 함유되어있는 성분이 금속 폭로에 영향을 주었다. 3. 전자세에서 용접흄의 폭로농도와 용접전류사이의 상관관계가 r=0.93으로 가장 높았고, 아래보기와 수평자세에서 용접흄 폭로농도와 헬멧에서 아크까지의 거리사이의 상관관계가 r=0.39으로 가장 높았다. 용접자세에 따른 용접흄 폭로농도에 있어 헬멧에서 아크까지의 거리보다는 용접시 이용되는 용접전류가 더 큰 영향을 주었다. 4. 아래보기와 수평자세에서 공히 용접흄의 폭로 농도가 높을 수록 용접 와이어의 성분인 철, 망간, 구리, 아연의 폭로농가 높은 경향을 보였다. 5. 용접자세에 따른 금속의 복합영향에 있어서 용접자세에 따라 다소 차이가 있었으나 용접 와이어에 함유되어있는 주성분인 철, 망간, 구리가 복합영향에 대한 기여도가 큰 경향이 있었다. 6. 3 개군 모두에서 용접흄의 폭로농도가 높을 수록 복합영향도 높은 경향이 있는 것으로 나타났다. CO₂welders(n=95) using AWS ER70S-6, 1.2mm diameter solid wire were examined and 95 CO₂welders were consisted of 34 all position, 30 downward & horizontal, and 31 overhead & vertical welders. To measure personal exposure for welding fumes and metals, full-period consecutive sampling was used. The results were as follows : 1. Welding fume exposure of 15.83 ㎎/㎥ , welding currents of 257.83 ampere and helmet-to arc distance of 44.87㎝ in downward & horizontal position was the highest and the longest of the three welding positions. 2. Metal exposures of iron, manganese, copper, zinc in downward & horizontal positions were the highest of the three welding positions and the concentrations were 5.254 ㎎/㎥, 0.849 ㎎/㎥, 0.072 ㎎/㎥, 0.048 ㎎/㎥, respectively. 3. Correlation coefficient of 0.93 between welding fume exposures and welding currents in all position was the highest of the three welding positions and correlation coefficient of 0.39 between welding fume exposures and helmet-to arc distances in downward & horizontal positions was the highest of the three welding positions. According to welding fume exposures by welding positions, welding currents had more effect than helmet-to arc distances. 4. Increasing welding fume exposures in downward & horizontal positions, metal components of iron, manganese, copper in welding wire and especially, zinc of base metal were observed. 5. Combined effects of metals by welding positions were some differences but iron, manganese, copper of welding wire major components were the trend that contributes to combined effects(CE). 6. Increasing welding fume exposures in 3 welding positions, combined effects were also high.

하구염도모델의 해석

이재형,정만,김경수 全北大學校 1990 論文集 Vol.32 No.-

In this study, two-dimensional estuarine model was analyzed by finite difference method. This is the coupled model, which is composed of the transport(Chu, 6) & hydrodynamic equation(Chiang, 5). The results, which were tested the appication of the model, as follows; (1) The results of the test show that the convergence of the algorithm depends upon the magnitude of the velocities ; the initial condition of salinities ; and the convergence criteria in the algorithm. (2) When the computed results are compared with the model of Chu(6), the salinities was conformed to the boundary and the central part of the basin have the large value, 1 ppt. (3) If the hydrodynamic values(E, U, V) were computed accurately, the salinitines also were suitable.

FDM에서 경사면의 표면과 면적오차법의 관계에 대한 연구

전재억,정진서,황영모,김수광,김준안,계중읍,하만경 한국공작기계학회 2002 한국공작기계학회 추계학술대회논문집 Vol.2002 No.-

In any rapid prototyping process, the layer by layer building process introduces an area error between the staircase and the surface line specified by the computer-aided design model. This affects the dimensional accuracy as well as the surface finish for different part build orientations. This paper describes a methodology for computing the area error for any orientation of the part built by the fused deposition modelling system. This technique can be applied to determine the best build orientation of the part, based on the minimum area error. This technique is verified by comparing the results with the experimental measurements of the area error of the parts built at different orientations.

水容性造影劑를 使用한 腰椎簡核脫出症의 脊髓腔撮影에 關한 硏究

金載敞,鄭萬翼,李方炘 최신의학사 1975 最新醫學 Vol.18 No.2

For last 5 years (1968-1973) lumbar myelography with water soluble contrast medium (Myelotrast or abrodil, sodium-monoiodomethyl sulphonyl ICH, SO, Na) has been performed in 324 patients who were impressed or diagnosed as lumbar disc herniation in Radiological Department of National Medical Center, Seoul, Korea. The results areas followings. 1) Age and sex distibutions were male 180, female 144 and from 12 to 68 year old. Highest incidence is noted in 30-39 age group (91 cases). 2) In simple film, spondylosis was noted in 96 cases(29.6%). scolisois in 79(24.4%), straightening in 62(19. 1%) and disc space narrowing in 154(48%). 3) The distribution of disc space narrowings (154) in simple film is highest in L,-Ls level (113) and 22 in Ls-S, level, 18 in L3-L, level etc. 4) In lumbar myelography, positive findings in 180 cases (55.5%), non-specific in 124 cases (33.3%) and borderline in 20 cases (6.2 %) . A) The contents of the positive fingings(180) are single disc herniation in 154 cases multiple disc herniation in 26 cases. b) The distribution of single disc herniation (154) are 122 cases in L,-Ls level, 23 cases in Ls-S, level etc. c) In multiple lesions(26), highest incidence in L,-L5-S, level 14 cases and 8 cases in L,-L,-L5 level etc. 5) Surgical operation was performed in 135 cases (41. 6% of all). 6) Comparing myelographic findings with operative findings, false negative(radiologically free but positive in surgery) in 6 cases (5% of operation case), false positive(radiologically positive but free in surgery) in 2 cases(1% of surgery case) and 94%(127) was detactable in myeloraphy preoperatively. 7) Advantages of the water soluble contrast medium in lumbar myelography.For last 5 years (1968-1973) lumbar myelography with water soluble contrast medium (Myelotrast or abrodil, sodium-monoiodomethyl sulphonyl ICH, SO, Na) has been performed in 324 patients who were impressed or diagnosed as lumbar disc herniation in Radiological Department of National Medical Center, Seoul, Korea. The results areas followings. 1) Age and sex distibutions were male 180, female 144 and from 12 to 68 year old. Highest incidence is noted in 30-39 age group (91 cases). 2) In simple film, spondylosis was noted in 96 cases(29.6%). scolisois in 79(24.4%), straightening in 62(19. 1%) and disc space narrowing in 154(48%). 3) The distribution of disc space narrowings (154) in simple film is highest in L,-Ls level (113) and 22 in Ls-S, level, 18 in L3-L, level etc. 4) In lumbar myelography, positive findings in 180 cases (55.5%), non-specific in 124 cases (33.3%) and borderline in 20 cases (6.2 %) . A) The contents of the positive fingings(180) are single disc herniation in 154 cases multiple disc herniation in 26 cases. b) The distribution of single disc herniation (154) are 122 cases in L,-Ls level, 23 cases in Ls-S, level etc. c) In multiple lesions(26), highest incidence in L,-L5-S, level 14 cases and 8 cases in L,-L,-L5 level etc. 5) Surgical operation was performed in 135 cases (41. 6% of all). 6) Comparing myelographic findings with operative findings, false negative(radiologically free but positive in surgery) in 6 cases (5% of operation case), false positive(radiologically positive but free in surgery) in 2 cases(1% of surgery case) and 94%(127) was detactable in myeloraphy preoperatively. 7) Advantages of the water soluble contrast medium in lumbar myelography. a) Completely and quickley resorbed and eXcreted from the body through the urine in d matter of minutes. b) Mixes completely and homogenusly with spinal fiuid. c) It can fill out every little corner of the spinal canal. d) Low incidence of pseudoindentation(1%). e) It is not so dense that fine spinal nerve to be visible through the contrast.

십이지장과 대장을 동시에 침범한 결핵 1예

이만재,박치영,곽재정,유보열,기장도,박찬국,김만우,김정용 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Tuberculosis of duodenum is so rare and is usually secondary to pulmonary or intestinal tuberculosis . It is difficult to diagnose duodenal tuberculosis in clinical and radiologic findings due to its non-specific symptoms and inconsistent lesion. The diagnosis was made on the basis of the histological study of the endoscopic biopsy and resected surgical specimen. so we report a case of tuberculosis of duodenal bulb and of ascending colon with, the brief review of the literatures.

전신진동에 대한 인체반응의 기준

김정만,정재열 동아대학교 부설 산업의학연구소 1999 산업의학연구소 논총 Vol.- No.4