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      • 전격성 경과를 취한 만성 호산구성 폐렴 환자 1예

        윤호상,진춘조,유광하,이상엽,이수인,정상만,김선두,이순제,이길도,전혜정 건국대학교 의과학연구소 2000 건국의과학학술지 Vol.10 No.-

        Chronic eosinophilic pneumonia(CEP) is a rare disease of unknown etiology characterized by chronic infiltration of the lung with eosinophils. It presents with profound systemic symptoms comprising fever, night sweats, weight loss, dyspnea and blood eosinophilia with nonsegmental air-space consolidation confined to the outer third of the lung, the "photographic negative of pulmonary edema". Histopathologic features of chronic eosinophilic pneumonia are intraalveolar and interstitial infiltrations with eosinophils, histiocytes, giant cells, scattered lymphocytes and plasma cells. Glucocorticoid therapy cause prompt resolution of symptoms as well as disappearans of blood eosinophils, elevated serum Ig E levels and the roentgenographic lesions. Infrequent radiographic findings include nodular infiltrates, consolidations, cavitations, atelectasis and pleural effusions. Deaths from CEP although rare, have been reported, but the majorities of CEP have benign courses and do not need a therapy with ventilator. We report a case of chronic eosinophilic pneumonia, which had a sudden course associated with diffuse pneumonic consolidations on the both lung and bilateral pleural effusion.

      • SCIESCOPUSKCI등재

        INSERTION-OF-FACTORS-PROPERTY WITH FACTORS MAXIMAL IDEALS

        Jin, Hai-Lan,Jung, Da Woon,Lee, Yang,Ryu, Sung Ju,Sung, Hyo Jin,Yun, Sang Jo Korean Mathematical Society 2015 대한수학회지 Vol.52 No.3

        Insertion-of-factors-property, which was introduced by Bell, has a role in the study of various sorts of zero-divisors in noncommutative rings. We in this note consider this property in the case that factors are restricted to maximal ideals. A ring is called IMIP when it satisfies such property. It is shown that the Dorroh extension of A by K is an IMIP ring if and only if A is an IFP ring without identity, where A is a nil algebra over a field K. The structure of an IMIP ring is studied in relation to various kinds of rings which have roles in noncommutative ring theory.

      • SCIESCOPUSKCI등재
      • KCI등재

        AAPM TG18에 의한 진단용 LCD 디스플레이 장치 정도관리 효과의 정량적 분석

        정해조,김희중,Jung Hai-Jo,Kim Hee-Joung 한국의학물리학회 2006 의학물리 Vol.17 No.2

        영상의 표시는 PACS 및 디지털 의료 영상계에서 중요한 요소이다. 동일한 디지털 데이터에 대한 영상의 질은 디스플레이 장치의 물리적 특성, 최적화된 설정 및 교정, 주위 불빛 조건 등에 의하여 영향을 받는다. 디스플레이 장치는 사용시간에 따라서 휘도 감소 및 설정값들의 변화에 의하여 성능이 저하된다. 디스플레이 시스템의 성능이 지속적으로 저하되기 때문에 일정한 주기마다. 정도관리를 수행하여야한다. 정도관리 효과를 평가하기 위하여 진단에 사용되는 10대의 평판 LCD 디스플레이 장치를 선택하였으며, 설정값 교정 전과 후에 휘도 반응, 휘도 공간 의존도, 분해능, 그리고 색도 변화를 정량적으로 측정하여 평가하였다. 정도관리 효과는 휘도 반응과 휘도 공간 의존도 테스트에서 다소 큰 변화가 있었으나 분해능 및 디스플레이 색도에서의 영향은 크지 않았다. 디스플레이 장치의 주기적인 정도관리는 의료영상을 일관성 있게 표시하기 위하여 필수적이다. 본 연구 결과는 의료용 디스플레이 장치의 정도관리에 대한 항목 선정 및 주기를 결정하는 데 중요한 역할을 할 수 있을 것이다. The image display is an Important component of PACS and of medical digital imaging chain. Displayed image qualify is affected by the physical characteristics of display device, appropriate clinical settings and calibrations, and ambient lighting conditions. The performance of display systems is continuously degraded over time due to luminance deterioration and changes of clinical setting parameters. A routine QC is recommended because the performance of display systems is continuously degraded over time. Ten flat panel monochrome LCD display devices were included in the evaluation of the QC effect. The effect of QC on primary class LCD medical display devices for selected QC tests was evaluated by comparing the performances, luminance response, luminance dependencies, display resolution and display chromaticity in this study, of before and after the calibration procedures. The effects of the QC are significant to luminance response and luminance spatial dependencies test and the other side, are slight to the display resolution and display chromaticity test. A routine QC of display device is essential for the consistency of medical image display and presentation. The study of the QC effects of display devices will play an important role in practical QC procedures of display devices.

      • KCI등재

        위험성 평가를 적용한 공정건물 화재보험료 절감방안-국내 모 전자회사 사례 중심으로-

        정문조 ( Moon Jo Jung ),박해천 ( Hai Chun Park ) 조선대학교 공학기술연구원 2012 공학기술논문지 Vol.5 No.2

        Fire insurance means a contract that insurer receive the fixed insurance premiums from insured person or an enterprise and compensate for their property damage caused by unexpected disasters. Fire insurance coverage for everyone is not obliged to join and level of guarantee can be changed by their will. Insensitivity towards safety that is prevalent in our society may grow if someone take out an insurance policy by subjective judgments. Therefore, this study verifies the correlation between electronics company`s fire accidents rate of each production building and election of their insurance coverage and suggest the reducing plan for insurance premiums.

      • KCI등재SCOPUSSCIE

        Inhibitory Role of TRIP-Br1/XIAP in Necroptosis under Nutrient/Serum Starvation

        Sandag, Zolzaya,Jung, Samil,Quynh, Nguyen Thi Ngoc,Myagmarjav, Davaajargal,Anh, Nguyen Hai,Le, Dan-Diem Thi,Lee, Beom Suk,Mongre, Raj Kumar,Jo, Taeyeon,Lee, MyeongSok Korean Society for Molecular and Cellular Biology 2020 Molecules and cells Vol.43 No.3

        Currently, many available anti-cancer therapies are targeting apoptosis. However, many cancer cells have acquired resistance to apoptosis. To overcome this problem, simultaneous induction of other types of programmed cell death in addition to apoptosis of cancer cells might be an attractive strategy. For this purpose, we initially investigated the inhibitory role of TRIP-Br1/XIAP in necroptosis, a regulated form of necrosis, under nutrient/serum starvation. Our data showed that necroptosis was significantly induced in all tested 9 different types of cancer cell lines in response to prolonged serum starvation. Among them, necroptosis was induced at a relatively lower level in MCF-7 breast cancer line that was highly resistant to apoptosis than that in other cancer cell lines. Interestingly, TRIP-Br1 oncogenic protein level was found to be very high in this cell line. Up-regulated TRIP-Br1 suppressed necroptosis by repressing reactive oxygen species generation. Such suppression of necroptosis was greatly enhanced by XIAP, a potent inhibitor of apoptosis. Our data also showed that TRIP-Br1 increased XIAP phosphorylation at serine87, an active form of XIAP. Our mitochondrial fractionation data revealed that TRIP-Br1 protein level was greatly increased in the mitochondria upon serum starvation. It suppressed the export of CypD, a vital regulator in mitochondria-mediated necroptosis, from mitochondria to cytosol. TRIP-Br1 also suppressed shikonin-mediated necroptosis, but not TNF-α-mediated necroptosis, implying possible presence of another signaling pathway in necroptosis. Taken together, our results suggest that TRIP-Br1/XIAP can function as onco-proteins by suppressing necroptosis of cancer cells under nutrient/serum starvation.

      • Prediction of gestational age at birth using an artificial neural networks in singleton preterm birth

        ( Jee-yun Lee ),( Soo-jung Jo ),( Eun-jin Jung ),( Kwang-sig Lee ),( Seung-woo Kim ),( Ho Yeon Kim ),( Geum Joon Cho ),( Soon-cheol Hong ),( Min-jeong Oh ),( Hai-joong Kim ),( Ki Hoon Ahn ) 대한산부인과학회 2018 대한산부인과학회 학술대회 Vol.104 No.-

        Objective: The Objective of the present study was to predict the gestational age at preterm birth using artificial neural networks for singleton pregnancy. Methods: Artificial neural networks (ANNs) were used as a tool for the prediction of gestational age at birth. ANNs trained using obstetrical data of 125 cases, including 56 preterm and 69 non-preterm deliveries. Using a 36-variable obstetrical input set, gestational weeks at delivery were predicted by 89 cases of training sets, 18 cases of validating sets, and 18 cases of testing sets (total: 125 cases). After training, we validated the model by another 12 cases containing data of preterm deliveries. Results: To define the accuracy of the developed model, we confirmed the correlation coefficient (R) and mean square error of the model. For validating sets, the correlation coefficient was 0.839, but R of testing sets was 0.892, and R of total 125 cases was 0.959. The neural networks were well trained, and the model predictions were relatively good. Furthermore, the model was validated with another dataset of 12 cases, and the correlation coefficient was 0.709. The error days were 11.58 ± 13.73. Conclusion: In the present study, we trained the ANNs and developed the predictive model for gestational age at delivery. Although the prediction for gestational age at birth in singleton preterm birth was feasible, further studies with larger data, including detailed risk variables of preterm birth and other obstetrical outcomes, are needed.

      • KCI등재

        사료급여체계가 재래종 및 교잡종 흑염소의 영양소 이용율, 질소축적 및 혈액성상에 미치는 영향

        정기웅(Gi Woung Jung),조익환(Ik Hwan Jo),황보순(Soon Hwangbo),이성훈(Sung Hoon Lee),송해범(Hai Bum Song) 한국초지조사료학회 2008 한국초지조사료학회지 Vol.28 No.4

        본 시험은 흑염소의 효율적인 사양관리체계의 확립에 기여하기 위하여, 재래흑염소 10두(♂)와 교잡흑염소(재래흑염소×호주야생염소 교잡종; 50:50%) 10두(♂)를 공시하여, 시판 배합사료와 조사료를 급여하는 관행사료와 TMR 사료를 각각 급여하였을 때, 흑염소의 사료섭취량, 영양소소화율, 질소축적율 및 혈액성상에 미치는 영향을 조사하였으며, 실험기간은 사료 적응기간 14일 예비기간 10일을 거친 후, 14일간의 본 실험 기간을 두어 총 38일간 실시하였다. 결과를 살펴보면 1일 두당 건물의 섭취량은 TMR을 급여한 교잡종이 가장 높았고 (p<0.05), 품종간에서는 재래종 보다 교잡종이, 사료급여체계간에는 관행구보다 TMR구가 높았다(p<0.05). 일당증체량은 재래종 관행구, 재래종 TMR구, 교잡종 관행구, 교잡종 TMR구의 순으로 유의하게 높아졌다(p<0.05). 건물 소화율은 사료급여체계간에서는 TMR구가 관행구 보다 유의하게 높았으며, 품종간에도 교잡종이 재래종 보다 높았다(P<0.05). 질소축적량 및 질소축적율은 교잡종 TMR구가 가장 높았고, 재래종 관행구가 가장 낮았다(p<0.05). 혈중 glucose의 함량과 PUN (plasma urea nitrogen)은 교잡종이 재래종 보다 유의하게 높았다(P<0.05). 이상의 결과를 종합하면, TMR형태의 사료급여가 재래종 보다는 교잡종에 흑염소의 생산성과 사료섭취량, 소화율, 질소축적율 및 혈액성장에 양호한 영향을 나타내어, 효율적인 사양관리체계의 확립과 함께 흑염소 생산농가에 경제적 이득을 줄 수 있을 것으로 판단된다. This trial was conducted to investigate effects of different feeding types of conventional or total mixed rations (TMR) provision on feed intake, nutrient digestibility, nitrogen retention and blood metabolite characteristics in different breeds of native and cross bred Korean black goats. Ten Korean native male goats and 10 Korean crossbred black male goats (Korean native×Australian feral crossbred, 50:50), average 18㎏ of BW, were used in this trial, and each breed of Korean black goats was separated into conventional and TMR diets treatments in a randomized complete block design. Conventional diet was based on forages and commercial diet. All animals were housed in individual metabolism crates and were fed ad libitum. Water was available at all times. Experimental period totally lasted for 38 days, consisting of 14 days of adaptation, 10 days of preliminary period and 14 days of sample collection period. Daily dry matter intake was significantly (p<0.05) higher in TMR treatments of the crossbred goats. Within breeds, crossbred rather than native-bred consumed more highly, and within the feeding type, TMR diets were more fed in comparison with conventional diet. Average daily gain ranked the highest in crossbred : TMR, followed by crossbred : conventional diet, native-bred : TMR, and native-bred : conventional diet (p<0.05). Dry matter digestibility was significantly (p<0.05) higher for TMR than for conventional diets, and it was higher in crossbred than in native-bred Korea black goats. Nitrogen retention was highest in TMR treatments of crossbreed, whereas it was lowest in conventional diet of native breed (p<0.05). Plasma glucose and urea nitrogen concentrations were significantly (p<0.05) higher in crossbred than in native-bred Korean black goats. Overall, the results indicated that feeding total mixed ration to crossbred rather than native-bred Korean black goats had more favourable influences on their performances, intakes, digestibility, nitrogen retention and blood metabolite characteristics. In conclusion, it is conceived that the results may contribute to economical benefit to farms producing Korean black goats together with establishment of an efficient feeding management system.

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