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      • 삼선동5가 이층한옥상가에 대한 조사연구

        문정기,송인호 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1

        2-Storey Hanok for commerce which appeared with modernization of Seoul was being changed with closed relationship of transformation of urban structure. Especially, the 2-Storey Hanok in Samsungdong 5-ga which developed at the same time both urban housing block and housing type is distinguished from earlier model(1910~40's 2-Storey Hanok for commerce). The typological characters were analized as follows; 1) Don-am district had been divided with grid for a short period of time, and it has a district for commercial street motivated to construct Samsungdong 5-ga 2-Storehy Hanok for commerce. 2) The type of 2-Storey Hanok for commerce is completed by adding the ㄱ-shaped unit(the living part) to the ㅡ-shaped unit(the 2-storey part) which faced to the main road in the subdivided plot. But this layout is being transformed when plot conditions change. 3) The 2-storey Hanok for commerce has a united structural system of the 2-storey part and the living part, and they were built with continous wooden-column. Samsundong 5-ga 2-Storey Hanok for commerce which located at the last period of construction has a feature of the simplicity in plan and the united structural system caused by economical reason. Those can be considered as reflections of the fact that 2-Storey Hanok for commerce became as a common architectural typology.

      • SCIESCOPUSKCI등재

        PCR Diagnosis of Entamoeba histolytica Cysts in Stool Samples

        Joung-Ho Moon,Shin-Hyeong Cho,Jae-Ran Yu,Won-Ja Lee,Hyeng-Il Cheun 대한기생충학열대의학회 2011 The Korean Journal of Parasitology Vol.49 No.3

        Amebiasis is a protozoan disease caused by Entamoeba histolytica and a potential health threat in areas where sanitation and hygiene are inappropriate. Highly sensitive PCR methods for detection of E. histolytica in clinical and environmental samples are extremely useful to control amebiasis and to promote public health. The present study compared several primer sets for small subunit (SSU) rDNA and histone genes of E. histolytica cysts. A 246 bp of the SSU rDNA gene of pure cysts contained in phosphate-buffered saline (PBS) and in stool samples was successfully amplified by nested PCR, using the 1,147-246 bp primer set, of the primary PCR products which were pre-amplified using the 1,147 bp primer as the template. The detection limit of the nested PCR using the 1,147-246 primer set was 10 cysts in both groups (PBS and stool samples). The PCR to detect histone gene showed negative results. We propose that the nested PCR technique to detect SSU rDNA can be used as a highly sensitive genetic method to detect E. histolytica cysts in stool samples.

      • SCIESCOPUSKCI등재

        Resistance to Toxoplasma gondii Infection in Mice Treated with Silk Protein by Enhanced Immune Responses

        Joung-Ho Moon,Kyoung-Ho Pyo,Bong-Kwang Jung,Hyang Sook Chun,Jong-Yil Chai,Eun-Hee Shin 대한기생충학열대의학회 2011 The Korean Journal of Parasitology Vol.49 No.3

        This study investigated whether elevated host immune capacity can inhibit T. gondii infection. For this purpose, we used silk protein extracted from Bombyx mori cocoons as a natural supplement to augment immune capacity. After silk protein administration to BALB/c mice for 6 weeks, ratios of T lymphocytes (CD4+ and CD8+ T-cells) and splenocyte proliferative capacities in response to Con A or T. gondii lysate antigen (TLA) were increased. Of various cytokines, which regulate immune systems, Th1 cytokines, such as IFN-γ, IL-2, and IL-12, were obviously increased in splenocyte primary cell cultures. Furthermore, the survival of T. gondii (RH strain)-infected mice increased from 2 days to 5 or more days. In a state of immunosuppression induced by methylprednisolone acetate, silk protein-administered mice were resistant to reduction in T-lymphocyte (CD4+ and CD8+ T-cells) numbers and the splenocyte proliferative capacity induced by Con A or TLA with a statistical significance. Taken together, our results suggest that silk protein augments immune capacity in mice and the increased cellular immunity by silk protein administration increases host protection against acute T. gondii infection.

      • KCI등재후보

        Primary rectal mature teratoma: a case report

        Ho-chang Lee, Yong-Moon Lee, Joung-Ho Han 충북대학교 동물의학연구소 2013 Journal of Biomedical and Translational Research Vol.14 No.4

        This report describes a rare case of primary rectal mature teratoma in a 56-year-old woman. She was referred to the outpatient clinic with a large pedunculated rectal mass, which was found during a regular health check-up. Polypectomy was performed and microscopic findings showed various structures derived from all three germ cell layers. Epidermis, hair follicles, sebaceous glands, eccrine glands, and apocrine sweat glands, with some scattered melanophages and lymphocytes were present as ectodermal derivatives. Smooth muscle fibers, blood vessels, and fibrous and adipose tissues were found as mesodermal derivatives. In addition, thyroid follicles, mucinous glands, and bronchial respiratory epithelium with peribronchial glands were detected as endodermal derivatives. She is healthy and has shown no evidence of recurrence or distant metastasis for 25 months post-surgical resection. Primary rectal teratomas are generally benign and primarily affect women. Therefore, minimally invasive surgical procedures, such as endoscopic polypectomy for a pedunculated polyp and segmentectomy for a larger mass, are satisfactory in most cases. Induction of primary rectal teratomas has been suggested to occur mainly by errors in a single germ cell after the end of meiosis I; in addition, it has also been suggested that the difference in gender incidence may be associated with differences in sex chromosomes between males and females rather than with anatomical proximity between ovary and rectum.

      • SCOPUSKCI등재
      • KCI등재

        Conversion to Veno-arteriovenous Extracorporeal Membrane Oxygenation for Differential Hypoxia

        Cha Ho Jeong,Kim Jong Woo,Kang Dong Hoon,Moon Seong Ho,Kim Sung Hwan,Jung Jae Jun,Yang Jun Ho,Byun Joung Hun 대한심장혈관흉부외과학회 2023 Journal of Chest Surgery (J Chest Surg) Vol.56 No.4

        Background: Patients who require initial venoarterial extracorporeal membrane oxygenation (VA ECMO) support may need to undergo veno-arteriovenous ECMO (VAV ECMO) conversion. However, there are no definitive criteria for conversion to VAV ECMO. We report 9 cases of VAV ECMO at Gyeongsang National University Changwon Hospital, Gyeongsang National University College of Medicine. Methods: Of 158 patients who received ECMO support between January 2017 and June 2019, 82 were supported by initial VA ECMO. We retrospectively reviewed the medical records of 9 patients (7 men and 2 women; age, 53.1±19.4 years) who had differential hypoxia and required VAV ECMO support. Percutaneous transaortic catheter venting was used to detect the differential hypoxia. Results: Among the 82 patients who received VA ECMO support, 9 (10.9%) had differential hypoxia and required conversion to VAV ECMO support. The mean time from VA ECMO support to VAV ECMO support and the mean duration of the VAV support were 2.1±2.2 days and 1.9±1.5 days, respectively. The average peak inspiratory pressure before and after VAV ECMO application was 23.89±3.95 cmH2O and 20.67±5.72 cmH2O, respectively, decreasing by an average of 3.2±3.5 cmH2O (p=0.040). The PaO2/FiO2 ratio was kept below 100 mm Hg in survivors and non-survivors for 116±65.4 and 250±124.9 minutes, respectively (p=0.016). Six patients underwent extracorporeal cardiopulmonary resuscitation, of whom 4 survived (67%). The overall survival rate of patients who underwent conversion from VA ECMO to VAV ECMO was approximately 56%. Conclusion: Rapid detection of differential hypoxia is required when VA ECMO is applied, and efficient conversion to VAV ECMO may be critical for patient survival.

      • 지역정보화 전략:이슈와 연구방향

        문덕중,조영호 亞州大學校 1990 論文集 Vol.13 No.-

        Korea has seen a remarkable progress in information industry and telecommunication in the '80's.Where as some researchers predict the decentralzaition according to the development of information technology,she has been faced during this period with a phenomenon of growing centralzation toward the capital(Seoul)in information flow.This phenomenon threats a balanced regional development.The development of regional information and communication infrastucture has become a social concern since last few years. But,the existing researches fail to give an integrative view concerning this problem. This paper aimed to identify strategic issues for regional informationzation from a comprehensive perspective.Six strategic issues were identified and discussed. They are:(1)Project managersissue,(2) Development approach issue,(3)Regional needs analysis issue,(4)Networking issue,(5)New media issue,and(6)Suporting system design issue.

      • KCI등재

        The Nationwide Incidence of Retinal Vein Occlusion Following Dialysis due to End-stage Renal Disease in Korea, 2004 through 2013

        Moon Tae Hwan,Han Joung-Ho,Kang Minseok,Kim Ji Soo,Kim Jin Young,Chae Ju Byung,권순길,Kang Gilwon,Kim Dong Yoon 대한의학회 2021 Journal of Korean medical science Vol.36 No.30

        Background: We investigated the incidence and risk of retinal vein occlusion (RVO) in endstage renal disease (ESRD) patients on dialysis in Korea. Methods: In this nationwide cohort study, we used Korean National Health Insurance Service data between 2004 and 2013 for analysis. ESRD patients who started dialysis from 2004 to 2013 and an equal number of controls were selected through propensity score matching. RVO incidence in both cohorts were calculated for 2004–2013 using washout data from 2003. The multivariable Cox proportional hazards model was used to assess the risk of RVO in dialysis cohort. The Kaplan-Meier method was used to generate the cumulative RVO incidence curve. Whether the dialysis modality affects the development of RVO was also evaluated. Results: In this study, 74,551 ESRD patients on dialysis and the same number of controls were included. The incidence of RVO was significantly higher in the dialysis cohort than in the control cohort (dialysis = 7.3/1,000 person-years [PY]; control = 1.9/1,000 PY; P < 0.001). The cumulative-incidence of RVO was also significantly higher in the dialysis cohort than in the control cohort (P < 0.001; log-rank test). However, there was no significant difference in the incidence of RVO between the two dialysis methods (P = 0.550; log-rank test). Conclusion: This study provided epidemiological evidence that receiving dialysis for ESRD could increase the risk of developing RVO. We also found a rapid increase in the incidence of RVO with a longer dialysis period. These results strengthen the relationship between retinal vascular disease and renal function.

      • KCI등재

        Physical and Intellectual Development of Korean Children in Relation to Family Formation Patterns

        Joung-Soon Kim(金貞順),Moon-Ho Chung(鄭文鎬),Sung-Jae Suh(徐聖濟) 한국인구학회 1992 한국인구학 Vol.15 No.2

        兄弟數, 出?順位, 出?터울, 母性의 出?時年齡等 家族形成 樣相은 兒童의 身體的發育 成長 및 知能發達과 ?한 關聯性을 보여 왔음이 世界여러나라 兒童을 對象으로 遂行된 硏究에서 報告되었다. 本 硏究는 兄弟數와 出?順位, 그리고 出?時 母性의 年齡은 兒童의 身體的 知能的 發達과는 逆相關關係를, 出?터울의 길이는 順相關關係를 나타낼 것이라는 假說을 證明하고자 1984年 韓國中學生 1, 2, 3學年 約 46,000名을 對象으로 遂行되었다. 地域別, 그리고 社會經濟的 狀態別 比較를 위하여 서울市 高所得層이 主로 居住하는 學區內의 中學校와 低所得層이 居住하는 學區內 中學校 各各 5個를 選定하고 江原道內 典型的 農村의 中學校 12個를 선정하여 身長, 體重, 坐高, 血球容積, 知能指數를 測定하였다. 이들 測定値들의 平均은 學父母와 담임선생님의 도움으로 作成된 家族形成 變數別로 比較되었으며 多重回歸分析과 部分相關分析으로 聯關性의 統計的 有意性을 檢定하였다. 同一年齡의 身體的 發育成長 指標들은 都市의 高所得地域 兒童들이 가장 優秀했으며 다음이 都市低所得 지역 아동이었고 農村兒童이 가장 貧弱하였다. 男女別 身體的發育地標들의 差異는 年齡이 많을수록 더 顯著했으며 年齡別 地域別 差異는 男學生에게서 더 두드러졌다. 平均 知能指數는 都市高所得地域 男學生들이 越等히 높아 114.8인데 比해 都市低所得地域 男學生들은 106.1, 그리고 農村 男學生들은 105.3%이었다. 男學生보다는 女學生의 知能指數가 낮았는데 이것은 대만兒童들도 女學生이 모든 年齡에서 男學生보다 낮았다는 報告와 一致하였다. 한편 都市低所得地域과 農村地域 學生들은 男女모두 平均知能指數가 비슷하였다. 家族形成變數들은 混亂變數들은 모든 制禦했을 경우에도 兒童들의 身體的 知能的 發達에 獨立的으로 영향을 미쳤다. 發育指標中에 知能指數와 형제수가 가장 가족형성 변수들과의 연관성이 ?했다.

      • KCI등재

        Prostate Specific Membrane Antigen mRNA in Blood as a Potential Predictor of Biochemical Recurrence after Radical Prostatectomy

        Joung, Jae Young,Cho, Kang Su,Chung, Han Soo,Cho, In-Chang,Kim, Jung Eun,Seo, Ho Kyung,Chung, Jinsoo,Park, Weon Seo,Choi, Moon Kyung,Lee, Kang Hyun The Korean Academy of Medical Sciences 2010 JOURNAL OF KOREAN MEDICAL SCIENCE Vol.25 No.9

        <P>We investigated whether the detection of prostate specific membrane antigen (PSMA) in blood preoperatively has predictive value for biochemical recurrence (BCR) after radical prostatectomy in patients with prostate cancer. All 134 patients scheduled to receive radical prostatectomy for prostate cancer were prospectively enrolled. The authors used nested reverse transcriptase-polymerase chain reaction (RT-PCR) assay to detect PSMA mRNA-bearing cells in peripheral blood, and analyzed the ability of PSMA mRNA positivity to predict BCR after surgery. PSMA-mRNA was detected in 24 (17.9%) patients by RT-PCR. Over a median follow-up of 20 months (range, 3 to 46 months), BCR developed in 15 patients (11.2%) and median time to BCR was 7 months (range, 3 to 25 months). Kaplan-Meier analysis revealed a significant difference between those positive or negative for PSMA in terms of recurrence-free actuarial probability (log rank <I>P</I>=0.0039). Multivariate analysis showed that positivity for PSMA mRNA (HR: 3.697, 95% CI 1.285-10.634, <I>P</I>=0.015) and a biopsy Gleason score of ≥7 (HR: 4.500, 95% CI 1.419-14.274, <I>P</I>=0.011) were independent preoperative predictors of BCR. The presence of PSMA mRNA in peripheral blood can be used to predict BCR after radical prostatectomy.</P>

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