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우라늄 分離定量에 있어서 Amberlite LA-2의 利用
尹鉉勝,鄭昌雄,金演斗 충남대학교 자연과학연구소 1980 學術硏究誌 Vol.7 No.2
The liquid anion exchanger, Amberite LA-2, has been used to separate the trace amount of uranium from synthetic graphite in sulfuric acid solution As reducing the impurity metals with NaHSO_(3) the complete extraction of uranium has been made successfully in organic phase. The mixed solution, NaOH-HClO_(4)-H_(2)O_(2), was found to be good solution for stripping and developing of the uranium complex.
金玧廷,鄭均樂 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.2
An imoportant step in VLSI physical design is to determine the orientation of modules after floorplanning. After modules are placed according to some placement algorithm, circuit performance and routability can be affected by either flipping modules about their vertical and/or horizontal axes of symmetry or rotating modules while keeping the module placement fixed. MFA algorithm exhibits the rapid convergence of the neural networks while preserving the solution quality afforded by simulated annealing. In this paper, we have implemented 3 versions of Meanfield Annealing Algorithms for the problem of minimizing total wire length by flipping modules and compared the solution and execution time.
분광광도법에 의한 염화철중 규소의 정량에서의 Amberlite LA-2의 이용
김연두,배준현,정현옥 충남대학교 자연과학연구소 1988 忠南科學硏究誌 Vol.15 No.1
For the photometric determination of silicon in the iron(Ⅲ) chloride, the iron(Ⅲ) was extracted to organic phase with Amberlite LA-2 in the cons. HCl solution. In the residual aqueous solution, the silicon was determined by molybdenum blue method. The method was found to be very useful to determine a low concentration of silicon in the concentrated iron sample.
Thioacetamide에 의한 BALB/c 마우스 간의 시간별 약물대사효소 억제 양상 : A Time-Course Study
이정운,고우석,김갑호,배연경,하현정,한상섭,천영진,정태천 영남대학교 약품개발연구소 2001 영남대학교 약품개발연구소 연구업적집 Vol.11 No.-
Thioacetamide is a potent hepatotoxicant which requires metabolic activation by cytochrome P450s (P450s) for toxicity. In the present study, the elevation kinetic of serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST) activities by thioacetamide treatment was investigated in male BALB/c mice. Inaddition, the inhibitory effects of thioacetamide on liver microsomal P450 enzymes were further investigated. Thioacetamide at 100 mg/kg/ was treated intraperitoneally for 6, 12, 24, 36, 48 and 72 hr. The blood was collected at the designated time for assaying the serum enzyme activities. To determine the P450 isozyme-specific activities. ethoxyresorufin O-deethylase (EROD), methoxyresorufin O-demethylase (MROD), and benzyloxyresorufin O-debenzylase (BROD) activities were determined for P450 1A1, 1A2 and 2B1, respectively, in liver microsomal fractions. The activities of ALT and AST were started to be elevated 6 hr after thioacetamide treatment andreached the maximun at 36 hr after the treatment. The elevated activities were dramatically recovered at 72 hr. The microscopic exmination of the liver specimen also showed a similar profile of hepatotoxicity. All P450-associated enzyme activities were time-dependently inhibited by the treatiment with thioacetamide. The maximum inhibition of P450 enzymes was observed 36 hr after the treatment. Because the inhibition of P450 enzymes by thioacetamide was time-dependent, our present results suggest that thioacetamide might inhibit P450 enzymes in mechanism-based inactivation.