개에서 17-ODYA가 신혈류량 자동 조절에 미치는 영향

양훈모,민영기,박중섭 순천향의학연구소 1999 Journal of Soonchunhyang Medical Science Vol.5 No.1

17-ODYA is a potent inhibitor of the formation of 20-hydroxyeicosatetraenoic acid, epoxyeicosatrienoic acids and dihydroeicosatetraenoic acids by renal cortical microsomes. This study characterized the effects of intrarenal infusion of 17-ODYA on renal blood flow (RBF) and autoregulation of RBF. Seven dogs were prepared for the measurements of RBF, mean systemic and renal perfusion pressure. The renal perfusion pressure was able to be adjusted to desired levels by an inflatable supra-aortic occluder. Intrarenal infusion of 17-ODYA produced a diuresis and a natriuresis but no change in RBF. 17-ODYA had no effect on autoregulation of RBF: Both the plateau and steep portrions. of the autoregulatory curves were identical to control. Thesholds for lower limit of autoregulation were 72±4 and 72±5 mmHg during control and 17-ODYA and not significantly different from each other. These results suggest that endogenous cytochrome P-450 metabolites of AA do not influence RBF autoregulatory capacity in dogs.

발생원별에 따른 PAHs 배출특성

박찬구,윤중섭,김민영,손종열,모세영 한국대기환경학회 2004 한국대기환경학회지 Vol.20 No.3

The results of individual PAH source profiles that can be applied to receptor model are as follows. The sum of 16 PAH concentrations was 391.41 ng/S㎥ in a tunnel. Phenanthrene was the most abundant compound among 16 PAH, and then pyrene, fIuoranthene, anthracene, and naphthalene can be seen in elevated contents. 11,056.61 ng/S㎥ of 16 PAH concentrations in BC oil boiler was two times higher than 6,582.57 ng/S㎥ of those in LNG boiler. Naphthalene was the most abundant compound in both facilities. Phenanthrene, anthracene. and acenaphthylene were the second dominant compound group in order from both facilities. BC oil boiler had relatively high concentration of pyrene compared to LNG boiler that had high concentration of fluorene and did not detect pyrene. The sum of 16 PAH concentrations emitted from MSW incinerators after APCD (air pollution control device) was three times higher than those from MSW incinerators bcfore APCD. However, the concentrations of more than 4-ring PAH compounds (e.g., benzo (a)anthracene) before APCD were higher than those after APCD. This fact implies that PAHs generated by combustion process are eliminated in APCD and they are continuously produced in stack or atmosphere by PAHs precursors.

이동량 보상 및 분류 벡터 양자화기

박규태,전중남,신태민,연창모 연세대학교 산업기술연구소 1987 논문집 Vol.19 No.2

This study describes an interframe image coding method using motion compensated and classified vector quantization(MC-CVQ). In motion compensated vector quantization(MCVQ), it is very important to encode the significant block. Therefore, we propose the MC-CVQ which encodes the significant block in the motion compensated error image by the classified vector quantizer. We classify the significant blocks according to the positions of the significant vectors, and also classify the significant vectors into 15 classes according to the positions of the significant pels. The computer simulation shows that the signal-to-noise ratio and the average bits of MC-CVQ are 0.2-0.25 bits/pel and 35 to 37 dB, respectively.

기능성 소화불량증환자에서 Winstal® 투여에 관한 임상경험

이창형,김영탁,금민수,권중구,안병철,윤영미,권영오,김성국,최용환,정준모 慶北大學校 醫科大學 1994 慶北醫大誌 Vol.35 No.3

목적 : 기능성 소화불량증은 소화, 흡수등 장관의 기능적인 이상과 관련되어 있을 것으로 생각되며 복합소화효소제(Winstal®)를 투여하여 그 임상효과를 평가하고자 본 연구를 실시하였다. 대상 및 방법 : 1994년 3월 부터 6월까지 경북대학교병원 내과를 방문한 기능성 소화불량증을 호소하는 환자 20명을 대상으로 Winstal®을 1회 1정씩, 1일 3회 식후 30분내에 경구로 2주간 투여하였다. 결과 : 소화불량증의 증상은 복부불쾌감, 복부팽만감, 식욕부진 및 오심, 복부동통, 공기연하증, 고창 및 구토순이었으며, 증상의 개선은 복부불쾌감이 76.4%(13/17)로 가장 높았으며, 그 다음으로 복부팽만감 및 공기연하증이 66.5%(10/15, 6/9)이었고, 오심 61.5%(8/13), 식욕부진 53.8%(7/13), 복부동통 41.6%(5/12), 고창 37.5%(3/8)이었다. 각 환자별 종합적인 증상의 개선도는 현저한 개선이 2예(10%), 중등도 개선이 3예(15%), 약간개선이 11예(55%), 불변이 4예(20%)이었으며 종합적인 유효율은 80%(16/20)이었다. 부작용은 한 예에서도 관찰되지 않았다. 결론 : 본 제제는 기능성 소화불량증 환자의 증상개선에 추천할 만한 유효한 약제로 생각된다. Dyspepsia is a common symptom in gastroenterologic practice and trigger for numerous consultations with physician. The treatment of chronic functional dyspesia is unsatisfactory. This study was performed to evaluate the efficacy of the digestive compound (Winstal®) on 20 functional dyspepsia patients. On open trial, all patients were given 6 tablets daily for 2 weeks and we evaluated the efficacy of this preparation according to the degree of the improvement. The improvement of symptoms was 76.4%(13/17) in abdominal discomfort, 66.5%(10/15, 6/9) in abdominal distension and aerophagia, 61.5%(8/13) in nausea, 53.8%(7/13) in abdominal pain, and 37.5% (5/12) in flatulence, respectively. Overall effectiveness of subjective symptoms was 80% (16/20) and there were no untoward effects of the preparations during this study. As a result, We think that this preparation is an effective one to relieve symptoms of functional dyspepsia.

FDM에서 경사면의 표면과 면적오차법의 관계에 대한 연구

전재억,정진서,황영모,김수광,김준안,계중읍,하만경 한국공작기계학회 2002 한국공작기계학회 추계학술대회논문집 Vol.2002 No.-

In any rapid prototyping process, the layer by layer building process introduces an area error between the staircase and the surface line specified by the computer-aided design model. This affects the dimensional accuracy as well as the surface finish for different part build orientations. This paper describes a methodology for computing the area error for any orientation of the part built by the fused deposition modelling system. This technique can be applied to determine the best build orientation of the part, based on the minimum area error. This technique is verified by comparing the results with the experimental measurements of the area error of the parts built at different orientations.

하계 실내 및 실외환경의 공기 중 휘발성 유기화합물 농도 및 개인노출

양원호,손부순,박종안,장봉기,박완모,김윤신,어수미,윤중섭,류인철 한국환경과학회 2003 한국환경과학회지 Vol.12 No.9

Volatile organic compounds (VOCs) are present in essentially all natural and synthetic materials from petrol to flowers. In this study, indoor and outdoor VOCs concentrations of houses, offices and internet-cafes were measured and compared simultaneously with personal exposures of each 50 participants in Asan and Seoul, respectively. Also, factors that influence personal VOCs exposure were statistically analyzed using questionnaires in relation to house characteristics, time activities, and health effects. All VOCs concentrations were measured by OVM passive samplers (3M) and analyzed with GC/MS. Target pollutants among VOCs were Toluene, o-Xylene, m/p-Xylene, Ethylbenzene, MIBK, n-Octane, Styrene, Trichloroethylene, and 1,2-Dichlorobenzene. Indoor and outdoor VOCs concentrations measured in Seoul were significantly higher than those in Asan except Ethylbenzene. Residential indoor/outdoor (I/O) ratios for all target compounds ranged from 0.94 to 1.51 and I/O ratios of Asan were a little higher than those of Seoul. Relationship between personal VOCs exposure, and indoor and outdoor VOCs concentrations suggested that time-activity pattern could affect the high exposure to air pollutant. Factors that influence indoor VOCs level and personal exposure with regard to house characteristics in houses were building age, inside smoking and house type. In addition insecticide and cosmetics interestingly affected the VOCs personal exposure. Higher exposure to VOCs might be caused to be exciting increase and memory reduction, considering the relationship between measured VOCs concentrations and questionnaire (p<0.05).

Effects of supplementing limiting amino acids on milk production in dairy cows consuming a corn grain and soybean meal-based diet

( Joong Kook Park ),( Joon-mo Yeo ),( Gui-seck Bae ),( Eun Joong Kim ),( Chang-hyun Kim ) 한국축산학회(구 한국동물자원과학회) 2020 한국축산학회지 Vol.62 No.4

Limiting amino acids (AAs) for milk production in dairy cows fed on a concentrate diet of corn grain and soybean meal was evaluated in this study. Four lactating and multiparous Holstein cows (in third or fourth parities, with an average body weight of 633 ± 49.2 kg), 8 to 9 weeks into their lactation period, were used in a 4 × 4 Latin square design. The experiment comprised four dietary treatments: (1) no intravenous infusion (control); (2) control plus intravenous infusion of an AA mixture of 6 g/d methionine, 19.1 g/d lysine, 13.8 g/d isoleucine, and 15.4 g/d valine (4AA); (3) control plus intravenous infusion of the AA mixture without methionine (no-Met); and (4) control plus intravenous infusion of the AA mixture without lysine (no-Lys). All animals were fed on a controlled diet (1 kg/d alfalfa hay, 10 kg/d silage, 14 kg/d concentrate mixture, ad libitum timothy hay). The AA composition of the diet and blood were determined using an automatic AA analyzer. Milk composition (protein, fat, lactose, urea nitrogen, and somatic cell counts) was determined using a MilkoScan. The results showed that feed intake for milk production did not differ from that of intravenous infusion using a limiting AA mixture. The 4AA treatment numerically had the highest milk yield (32.4 kg/d), although there was no difference when compared with the control (31.2 kg/d), no-Met (31.3 kg/d), and no-Lys (31.7 kg/d) treatments. The concentration of AAs in blood plasma of cows in all treatments, mainly isoleucine and valine, increased significantly compared with that of control. The no-Met treatment increased (p < 0.05) the concentration of lysine in the blood relative to the control and no-Lys treatments, whereas the no-Lys treatment increased (p < 0.05) the concentration of methionine relative to the control and no-Met treatments. In conclusion, milk production increased when feeding 10 g/d methionine to the cows, together with their concentrate diet of corn grain and soybean meal.

Effects of supplementing limiting amino acids on milk production in dairy cows consuming a corn grain and soybean meal-based diet

Park, Joong Kook,Yeo, Joon-Mo,Bae, Gui-Seck,Kim, Eun Joong,Kim, Chang-Hyun Korean Society of Animal Sciences and Technology 2020 한국축산학회지 Vol.62 No.4

Limiting amino acids (AAs) for milk production in dairy cows fed on a concentrate diet of corn grain and soybean meal was evaluated in this study. Four lactating and multiparous Holstein cows (in third or fourth parities, with an average body weight of 633 ± 49.2 kg), 8 to 9 weeks into their lactation period, were used in a 4 × 4 Latin square design. The experiment comprised four dietary treatments: (1) no intravenous infusion (control); (2) control plus intravenous infusion of an AA mixture of 6 g/d methionine, 19.1 g/d lysine, 13.8 g/d isoleucine, and 15.4 g/d valine (4AA); (3) control plus intravenous infusion of the AA mixture without methionine (no-Met); and (4) control plus intravenous infusion of the AA mixture without lysine (no-Lys). All animals were fed on a controlled diet (1 kg/d alfalfa hay, 10 kg/d silage, 14 kg/d concentrate mixture, ad libitum timothy hay). The AA composition of the diet and blood were determined using an automatic AA analyzer. Milk composition (protein, fat, lactose, urea nitrogen, and somatic cell counts) was determined using a MilkoScan. The results showed that feed intake for milk production did not differ from that of intravenous infusion using a limiting AA mixture. The 4AA treatment numerically had the highest milk yield (32.4 kg/d), although there was no difference when compared with the control (31.2 kg/d), no-Met (31.3 kg/d), and no-Lys (31.7 kg/d) treatments. The concentration of AAs in blood plasma of cows in all treatments, mainly isoleucine and valine, increased significantly compared with that of control. The no-Met treatment increased (p < 0.05) the concentration of lysine in the blood relative to the control and no-Lys treatments, whereas the no-Lys treatment increased (p < 0.05) the concentration of methionine relative to the control and no-Met treatments. In conclusion, milk production increased when feeding 10 g/d methionine to the cows, together with their concentrate diet of corn grain and soybean meal.

Numerical Modeling of Turbulent Spray Combustion Processes in HSDI Diesel Engines

( Hoo Joong Kim ),( Sung Mo Kang ),( Yong Mo Kim ),( Je Hyung Lee ),( Joon Kyu Lee ) 한국액체미립화학회 2004 한국액체미립화학회 학술강연회 논문집 Vol.2004 No.-

Numerical Simulation of Laminar Reacting Flows Using Unstructured Finite Volume Method With Adaptive Refinement

Sung-Mo Kang,Hoo-Joong Kim,Yong-Mo Kim 한국연소학회 2001 한국연소학회지 Vol.6 No.2