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      • 人蔘斑點病에 관한 營養生理學的 硏究 : Ⅱ. 菌의 生育과 水素 Ion 濃度 Vitamine 金屬鹽類 및 無機營養素와의 關係

        金倧熙,李敏雄 東國大學校 1968 論文集 Vol.5 No.-

        This is a study of the physiological nutrition source of Alternaria panax which causes a disease in the leaves of ginseng. The effects of hydrogen Ion concentration, trace element source of metal and inorganic nutrition on the growth of this fungus have been obtained. The effects of optimum hydrogen Ion concentration on the growth of this fungus in Waksman and potato liquid extract medium were respectively 5.5-6.0 and 4.0∼4.5 The hydrogen Ion concentration after culture altered its formal medium concentration; the strong acid changed into weak acid, and the strong alkali into weak alkali. The effects of number of thiamine concentration on the growth of this fungus were much enhanced when 16r thiamine concentration were added in the basal medium per 20cc, and the fungus growth in the thiamine control basal medium appreciably decreased. The hydrogen Ion coucentration changed a little bit into acidity. The effects of several kinds of biotin concentration on the growth of this fungus were progresed significantly when 20μr biotin per 10cc and 0.1PPM thiamine were added to the basal medium and the growth diminished when biotin control medium and 100μr biotin concentration were added. When the basal medium was supplemented with simple vitamine or a thiamine to each simple vitamine, the effects of each vitamine on the growth of this fungus showed that biotin and thiamine were best in each vitamine unit, and when the calcium chloride and the control of vitamine were matched, the effects were poor. In the case of calcium pantothenate added to thiamine, the growth was much enhanced but in case of calcium chloride added to thiamine, the growth was poor results. When thiamine each simple vitamine concentration was added in the basal medium generally the growth was much better than in the case of added to each vitamine concentration. In a mixed concentration boiled oatmeal extract medium was most effect on the growth of fungus, and the control of mixed or simple vitamine showed poor results. The hydrogen Ion concentration was changed appreciably into weak acidity. As for the effect of minimum metal source on the growth of fungus, an optimum Mol concentration of ferric chloride, Natrium molybdaenicum, zinc sulfate and Manganese sulfate were different in each Mol concentration: the ferric chloride was 1/1,000 Mol, natrium molybdaenicum 1/60,000 Mol, zinc sulfate 1/8,000 Mol and manganese sulfate also 1/10,000 Mol. The range of hydrogen Ion concentration after culture was generally changed into alkali region. As for the effect of inoganic nutritional elements on the growth of the fungus, the optimum range, the potassium phosphate monobasic, dibasic was 0.05%, magnesium sulfate 0.075%and calcium chloride 0.025%. Also all control of inorganic nutritional elements have showed unfavorable effects. The hydrogen Ion concentration was altered its formal hydrogen Ion concentration into weak acidity but majnesium sulfate was changed into weak alkali.

      • 원심모형시험에 의한 복개터널 복공의 변위특성에 관한 연구

        이명욱,박병수,이종호,유남재 강원대학교 산업기술연구소 2003 産業技術硏究 Vol.23 No.A

        This thesis is results of experimental works on the behavior of the cut-and-cover tunnel. Centrifuge model tests were performed to simulate the behavior of the cut-and-cover tunnels having cross sections of national road and subway tunnels Model experiments were carried out with changing the cut slope and the slope of filling ground surface Displacements of tunnel lining resulted from artificially accelerated gravitational force up to 40g of covered material used in model tests, were measured during centrifuge model tests In model tests. Jumunjin Standard Sand with the relative density of 80 % and the zinc plates were used for the covered material and the flexible tunnel lining. respectively Basic soil property tests were performed to obtain it's the property of Jumumjin Standard Sand Shear strength parameters of Jumunjin Standard Sand were obtained by performing the triaxial compression tests Direct shear tests were also carried out to find the mechanical properties of the interface between the lining and the covered material Compared results model tests estimation with respect to displacements of the lining

      • 상재하중에 의한 연약점토의 일차원 압밀에 관한 원심모형실험

        유남재,이명육,이종호 江原大學校 産業技術硏究所 1997 産業技術硏究 Vol.17 No.-

        This thesis is to investigate the one-dimensional consolidation behavior of soft marine clay with uniform surcharges by performing numerical and experimental works. Parametric experimental works of centrifuge model test were carried out changing test conditions of gravitational level in centrifuge, magnitude of surcharges and construction sequence of applying surcharges. Results of centrifuge model experiments were analyzed by using the numerical technique of explicit finite difference method based on the finite strain consolidation theory, being known to be appropriate to analyze the consolidational behavior of soft clay with a very high initial void ratio using the Lagrangian and the material coordinate systems. Test result were in relatively good agreements with analyzed results in terms of excess pore pressure dissipation and consolidation settlement with time and final void ratio distribution.

      • 단말뚝 거동에 관한 원심모형실험

        유재남,이명육,이종호 江原大學校 産業技術硏究所 1997 産業技術硏究 Vol.17 No.-

        This thesis is an experimental research of investigation behavior of single pile, subjected to the vertical compression loads, using the centrifuge facility located in the geotechnical engineering laboratory in Kangwon National University. Centrifugal model experiments of model pile were carries out changing diameter of model pile, relative density of sandy ground and the gravitational level applied in the centrifuge. Thus, their effects on the load-settlement behavior and the ultimate bearing capacity of pile were investigated. Experimental results obtained from centrifuge model tests were compared with the theoretical or semi-empirical equations to analyze values of ultimate bearing capacity of model pile. When we compare the ultimate bearing capacity of experimental results with the ultimate bearing capacity of theorical results, the experimental results appear more higher in the De Beer method and Meyerhof. Expecially, Terzaghi method is very same as the experimental results normally.

      • 준설토의 건조수축에 의한 강도증가 특성과 지지력에 관한 연구

        유남재,이종호,이명욱,김현주 강원대학교 산업기술연구소 2000 産業技術硏究 Vol.20 No.A

        This research is results of experimental and numerical works on characteristic of strength increase and bearing capacity in dredged and reclaimed soil due to desiccation shrinkage. For a soil sampled from southern coastal area in Korea, basic soil property tests and standard consolidation test with falling head permeability tests were carried out to obtain consolidational characteristics of soil. Double cone penetration test. laboratory vane test and unconfined compression test were also performed to investigate the change of shear strength with degree of desiccation. Model tests were performed in 1G environment and 30G level artificially accelerated condition by using the centrifuge model test facilities to investigate the bearing capacity of desiccated ground. Test results were analyzed by using the bearing capacity of desiccated ground. Test results were analyzed by using the theoretical and load-settlement characteristics method proposed by Meyehof & Hanna(1978). On the other hands, the numerical technique, using the finite strain consolidation theory considering the effect of desiccation was used to estimate the appropriate time of using heavy construction equipments in field with respect to strength increase due to desiccation.

      • Optical Detection of Enzymatic Activity and Inhibitors on Non-Covalently Functionalized Fluorescent Graphene Oxide

        Kang, Tae Woog,Jeon, Su-Ji,Kim, Hye-In,Park, Jung Hyun,Yim, DaBin,Lee, Hye-Rim,Ju, Jong-Min,Kim, Man-Jin,Kim, Jong-Ho American Chemical Society 2016 ACS NANO Vol.10 No.5

        <P>It has been of great interest to measure the activity of acetylcholinesterase (AChE) and its inhibitor, as AChE is known to accelerate the aggregation of the amyloid beta peptides that underlie Alzheimer's disease. Herein, we report the development of graphene oxide (GO) fluorescence-based biosensors for the detection of AChE activity and AChE inhibitors. To this end, GO was non-covalently functionalized with phenoxy-modified dextran (PhO-dexGO) through hydrophobic interaction; the resulting GO showed excellent colloidal stability and intense fluorescence in various aqueous solutions as compared to pristine GO and the GO covalently functionalized with dextran. The fluorescence of PhO-dex-GO remarkably increased as AChE catalyzed the hydrolysis of acetylthiocholine (ATCh) to give thiocholine and acetic acid. It was found that the turn-on fluorescence response of PhO-dex-GO to AChE activity was induced by protonation of carboxyl groups on it from the product of the enzymatic hydrolysis reaction, acetic acid. On the basis of its turn-on fluorescence response, PhO-dex-GO was able to report kinetic and thermodynamic parameters involving a maximum velocity, a Michaelis constant, and an inhibition dissociation constant for AChE activity and inhibition. These parameters enable us to determine the activity of AChE and the efficiency of the inhibitor.</P>

      • SCISCIESCOPUS

        Genetic variation in microRNA-binding site and prognosis of patients with colorectal cancer.

        Kim, Jong Gwang,Chae, Yee Soo,Lee, Soo Jung,Kang, Byung Woog,Park, Jae Yong,Lee, Eun-Jin,Jeon, Hyo-Sung,Park, Jun Seok,Choi, Gyu Seog Springer-Verlag 2015 JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY Vol.141 No.1

        <P>Single nucleotide polymorphisms (SNPs) located in the 3'-UTR of miRNA target genes could affect miRNA-mediated gene regulation, thereby contributing to the susceptibility or prognosis of cancer. Accordingly, the present study analyzed SNPs located at putative miRNA-binding sites of the 3'-UTR of various genes and investigated their impact on the prognosis for patients with colorectal cancer.</P>

      • Spotlights와 Maximally Stable Extremal Regions)영역 검출 기반의 조도변화에 강인한 교통신호등 검출 방안

        김종배 ( Jong-bae Kim ),장지웅 ( Ji-woog Jiang ) 한국정보처리학회 2013 한국정보처리학회 학술대회논문집 Vol.20 No.2

        교통 신호등은 운전자 혹은 보행자들의 뚜렷한 시인성 확보를 위해 가능한 주위 배경과 구분되는 색상, 모양, 질감 등으로 구성하여 설치되어 있는 특징을 가지고 있다. 결국 기존 교통 신호등 검출 연구들에서는 대부분 교통 신호등의 색상과 모양을 기반으로 한 검출 연구가 주류를 이루고 있는 것이 사실이다. 하지만, 외부 날씨, 복잡한 시내, 다른 물체와의 겹침 등의 문제로 인해 색상 및 모양 기반의 교통 신호등, motion blur, 검출 오류가 증가 되고 있다. 따라서 본 연구에서는 입력 영상에서 색상정보를 배제하고 motion blur나 밝기 변화에 덜 민감하고 먼 거리에서도 뛰어난 시인성을 가진 spotlight 검출을 통해 입력 영상에서 가장 밝은 교통표지판 후보 영역들을 검출한다. 그리고 교통 신호등의 특징인 가능한 원형을 유지하고 있으며 원형 외부 색상과 내부 색상이 현저하게 두드러지는 영역을 maximally stable extremal regions (MSER) 알고리즘을 사용하여 입력 영상에서 후보 영역을 선택한다. 마지막으로, 검출된 영역들에서 교통 신호등 영역을 검출하기 위해 템플릿 매칭 방법을 적용한다. 제안한 방법을 도로 상에서 실험한 결과, 평균 94% 이상의 검출율을 제시하였고, 특히 야간 시간대에 검출율이 비교적 높게 제시되었다.

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