작은 신종물에 대한 적극적 관찰

오종진(Jong Jin Oh),변석수(Seok-Soo Byun) 대한비뇨기종양학회 2010 대한비뇨기종양학회지 Vol.8 No.3

Although nephron sparing surgery is the current standard management of small renal masses (SRM), active surveillance is an option in selected patients. The natural history of SRM still remains to be elucidated. Initial size and tumor growth rate seem to predict the risk of malignancy in retrospective studies, even though a proportion of SRM with absent or slow growth can express significant malignant behavior. Biologic markers to predict the tumor biology also need to be investigated in the future. At present, active surveillance of SRM should only be considered in selected patients with poor candidate for surgery.

금속염화물 착색제 침투가 정방정 지르코니아 다결정체의 색조와 강도 변화에 미치는 영향

오종진 ( Jong Jin Oh ),노형록 ( Hyeong Rok Noh ) 한국치위생과학회 2015 치위생과학회지 Vol.15 No.5

본 연구에서는 1,040oC에서 예비소결한 Y-TZP 시편을 크롬 염화물 0.03∼0.08 wt%, 테르븀 염화물 0.03∼0.07 wt%를 함유한 금속염화물 수용액에 3분간 침지하고서 1,450oC에서 2시간 동안 소결하였으며, 이를 금속염화물 침투가 Y-TZP 소결체의 색상, 소결밀도, 굴곡강도 및 미세조직의 변화에 미치는 영향을 조사한 결과, 다음과 같은 결론을 얻었다. 지르코니아 예비소결체에 대한 크롬과 테르븀염화물 침투로 A1, A2 및 A3에 근사한 색조의 재현이 가능하였다. 크롬과 테르븀 염화물을 첨가했을 때 지르코니아의 결정립 크기가 증가하였다. Y-TZP 소결체의 2축 굴곡강도는 크롬과 테르븀 염화물 침투에 의해서 유의한 변화를 보이지 않았다(p>0.05). X-선 회절 분석결과, 크롬과 테르븀 염화물의 첨가 여부와 함량에 따른 지르코니아 결정상의 차이점은 관찰되지 않았다. 이상의 결과로 크롬과 테르븀 염화물을 사용하여 지르코니아의 색상을 조절할 수 있음을 확인하였고, 착색된 지르코니아의 색상은 Vita shade guide의 색상과 다소 차이가 있었지만 임상에서 이중구조 세라믹 보철물 재작 시 사용 가능할 것으로 생각된다. The purpose of this study was to evaluate the effect of metal chloride infiltration treatment on color and strength changes of the yttria-stabilized tetragonal zirconia polycrystals (Y-TZP). Fifty disc specimens were prepared with a Y-TZP powder (ZPEX; Tosoh, Japan). Thirty different metal chloride solutions containing 0.03∼0.08 wt% chromium and 0.03∼0.07 wt% terbium ions were prepared. Presintered Y-TZP specimens were soaked in metal chloride coloring liquids for 3 minutes and sintered in air at 1,450oC for 2 hours. The color of the specimens was measured with spectrophotometer and color difference (ΔE *) was obtained based on the CIE L *, a*, b* color coordinate values. To evaluate the effect of metal chloride infiltration strength changes, the biaxial flexural test was performed at crosshead speed 0.5 mm/min. Colors of the sintered Y-TZP showed the colors of Vita shade guide A1, A2 and A3 with the infiltration of chromium and terbium chloride solutions. Density of the sintered Y-TZP increased by the infiltration of chromium and terbium chloride solutions. Bi-axial flexural strength of the sintered Y-TZP did not show statistically significant differences by the infiltration of chromium and terbium chloride solutions (p>0.05). Chromium and terbium chloride did not affect the crystal phase of zirconia, and all specimens showed tetragonal phase. Accordingly, this study suggests that chromium and terbium chlorides can make colored zirconia while adding in a liquid form. The color of colored zirconia differ from that of vita shade guide but it can use all ceramic restoration as substructure in dental clinic.

서울시 재개발/재건축 단지의 소셜믹스에 대한 거주민 의식 및 실태조사

오종진(Oh, Jong-Jin),권오정(Kwon, Oh-Jung) 한국주거학회 2021 한국주거학회 학술대회논문집 Vol.33 No.2

The purpose of the study is to understand the consciousness of residents of social mix complexes supplied during the recent redevelopment/reconstruction process, identify the physical status of the survey target site, and propose a plan to successfully expand social mix complexes in the future. In order to understand residents’ consciousness and status of social mix, based on previous studies, it consisted of 25 questions in 5 areas including residents’ housing satisfaction, social mix complex, neighborhood bonds, actual use of community facility, and 6 socio-demographic questions. The results were as follows : 1) It is necessary to consider local, infrastructure, and community facilities before indiscriminately mixing pre-sale and rental-dong just to fill the volume. 2) Institutional improvement is needed to give everyone a same opportunity to participate communities. 3) Although both residents are mixed for the purpose of easing the floor area ratio, It is judged that social mixing is playing a net role in terms of policy. 4) Social mix policy should be accompanied by improving the consciousness of residents of mixed complexes.

전립선특이항원 및 전립선암 조기검진에 대한 대국민 인식조사 설문 결과

편종현(Jong Hyun Pyun),강석호(Seok Ho Kang),김지연(Ji Youn Kim),신재은(Jae Eun Shin),정인갑(In Gab Jeong),김종욱(Jong Wook Kim),노태일(Tae Il No),오종진(Jong Jin Oh),유지형(Ji Hyung Yu),정호석(Ho Seok Chung),전성수(Seong Soo Jeon) 대한비뇨기종양학회 2020 대한비뇨기종양학회지 Vol.18 No.1

Purpose: To assess awareness of prostate cancer and prostate cancer screening in high risk Korean men 40 years and older. Materials and Methods: The Korean Urological Oncology Society implemented an online survey of 600 men aged 40 years or older from July 30 to August 6, 2019 to ask questions about prostate cancer and screening. Results: Of the 600 respondents, 96.5% (579 of 600) were aware of prostate cancer and 49.8% (299 of 600) thought they were at risk. Men in their 60s, men with a family history and men with urological conditions were more concerned about prostate cancer. Most respondents (83.3%, 500 of 600) had never received prostate cancer screening. When asked why they had not, (multiple choices: first, second and third priority), the most common responses were: “They had no symptoms of prostate cancer”; “They were in good health”; “Cost burden of screening”; and “They thought screening was included in the National Health Examination Program.” Only 9.7% (58 of 600) were aware of prostate-specific antigen (PSA). After being informed about PSA, 97.7% (586 of 600) wanted it to be included in national cancer screening. Conclusions: In this survey, 96.5% of respondents were aware of prostate cancer, and 44.2% recognized the need for early screening. However, only 16.7% had received screening. Awareness of prostate cancer risks tended to be high in elderly people, people with a family history and people with urological conditions. The results also indicate that there is support for national-level management and early screening programs for prostate cancer.

PC3DR2 전립선암세포주의 Doxetaxel 내성 발현에서 세포고사관련 유전자의 이질적 발현

이학민(Hakmin Lee),호진녕(Jin-Nyoung Ho),이상철(Sang Chul Lee),오종진(Jong Jin Oh),홍성규(Sung Kyu Hong),이상은(Sang Eun Lee),변석수(Seok-Soo Byun) 대한비뇨기종양학회 2014 대한비뇨기종양학회지 Vol.12 No.2

Purpose: To understand the role of the apoptotic pathway of docetaxel- resistant human prostate cancer cell line (PC3DR2). Materials and Methods: PC3DR2 was established from the PC3 prostate cancer cell line by continuous exposure of escalating concentrations of docetaxel. Total RNA of PC3 and PC3DR2 were collected and cDNA microarray test was performed using GeneChip<SUP>ⓡ</SUP> Human Genome U133 Plus 2.0 Array. GenePlex<SUP>ⓡ</SUP> software was used for data analysis. Significantly different genes were identified with the cutoff 2.0 of fold change and p-value under 0.05 of Welch’s T-test. The apoptotic pathway heatmap was acquired to identify roles of apoptosis-related genes in development of docetaxel-resistance of PC3DR2. Results: There were 833 up-regulated and 908 down-regulated genes in the PC3DR2 compared to the control PC3. There were 72 significantly changed KEGG pathways in the PC3DR2 (cutoff: p<0.05). There were 3 up-regulated (TRADD and 2 FLIPs) and 6 down-regulated (IAP, IKK, Bax, Akt/PKB, PKA and calcineurin) genes in the apoptotic pathway. These 9 changes led to 4 pro-apoptotic and 5 anti-apoptotic processes, indicating contradictory changes in the pathway. Conclusions: Heterogeneous expressions of apoptosis-related genes were identified in the development of docetaxel resistance of the PC3DR2.

Perioperative Outcomes of Different Surgical Methods Among Bladder Cancer Patients Undergoing Radical Cystectomy With Neobladder Urinary Diversion

Hak Ju Kim(김학주),Changhee Ye(예창희),Jin Hyuck Kim(김진혁),Hwanik Kim(김환익),Sangchul Lee(이상철),Seok-Soo Byun(변석수),Jong Jin Oh(오종진) 대한비뇨기종양학회 2021 대한비뇨기종양학회지 Vol.19 No.4

Purpose: To compare perioperative outcomes according to surgical methods among bladder cancer patients who underwent radical cystectomy (RC) with neobladder urinary diversion. Materials and Methods: Between June 2007 and January 2020, 89 bladder cancer patients who received RC with neobladder urinary diversion were enrolled in this study. Patients were stratified into surgical methods – (1) open RC with neobladder (ONB) reconstruction, (2) robot-assisted RC (RARC) with extracorporeal neobladder (ECNB) reconstruction, and (3) RARC with intracorporeal neobladder (ICNB) reconstruction. Perioperative outcomes were compared among the 3 groups, with major complications defined according to Clavien-Dindo grades III–V within 90 days. Logistic regression analysis was performed to identify significant factors for postoperative complications. Results: Of 89 patients, 28 (31%) had ONB, 31 (35%) had ECNB, and 30 (34%) had ICNB. The median operative time was 471 minutes, and the ICNB group (424.5 minutes) was significantly less than ONB (444.5 minutes) and ECNB groups (542.9 minutes) (p=0.001). Transfusion rate was also significantly less in the ICNB group (13%) (p=0.001). Complications were recorded in 67 patients (75%) and major complications in 22 of all patients (25%). The major complication rate was significantly less in ICNB (13.4%) than in ONB (25%) and ECNB (35%) (p=0.003). Multivariate analysis showed surgical methods (ICNB) (odds ratio [OR], 0.709; p=0.003) and age (OR, 1.150; p=0.001) were significant factors related to occurrence of major postoperative complications. Conclusions: RARC with ICNB reduces postoperative complications compared to ONB and ECNB.

한국이주 무슬림의 혼인현황과 정착과정연구

조희선 ( Hee Sun Cho ),김대성 ( Dae Sung Kim ),안정국 ( Jung Kuk Ahn ),오종진 ( Jong Jin Oh ),김효정 ( Hyo Jung Kim ) 부산외국어대학교 지중해연구소 2009 지중해지역연구 Vol.11 No.3

This paper focuses on Marriage, Settlement and Acculturation of the Muslim Immigrants in Korean Society, as the second year subject of the project on "Acculturation and Adaptation of Immigrant Muslims in Korean Society: Coexisting with Koslims in a Multi-Cultural Society". The main purpose of this paper is to explore the Muslim immigrants` intermarriage with the Koreans and their settlement in the Korean society. To be sure, the growing number of foreign brides and bridegroom are one of the important social issues in the Korean Multi-cultural debate. To investigate the intermarriage situation efficiently from the various muslim immigrants, this study divided the muslim in Korea into five categories; Arab Muslims, non Arab Middle East Muslims, Central Asian Muslims, South Asian Muslims, and South East Asian Muslims. In order to outline the Muslim intermarriage status in Korea, this research has employed various statistic data as qualitative method. However this study was done mainly through field research using survey and a face-to-face interview to explain the peculiarity of the different Muslim communities` intermarriage trend in Korea. This study is one of the first to provide information about the intermarriage trend and the situation of the Muslim immigrants in Korea.

국소진행성 전립선암에서 저선량 근접치료의 적용

박동수(Dong Soo Park),장웅기(Woong Ki Jang),오종진(Jong Jin Oh),지상현(Sang Hyun Jee),신현수(Hyun Soo Shin) 대한비뇨기종양학회 2008 대한비뇨기종양학회지 Vol.6 No.3

한국사회 이주 무슬림 커뮤니티에 관한 연구 -유입, 적응, 사회적 네트워크를 중심으로-

조희선 ( Hee Sun Cho ),김대성 ( Dae Sung Kim ),안정국 ( Jung Kook Ahn ),오종진 ( Jong Jin Oh ),김효정 ( Hyo Jung Kim ) 한국외국어대학교 중동연구소 2008 중동연구 Vol.27 No.2

Korea is known as homeogenous nations throughout the history. But Korea`s long history of being a homogeneous nation is facing a rapid change as Korea is fast becoming a multi-ethnic society with a growing number of foreign migrant workers, international students, and inter-racial marriages. About a decade ago, Korea was a country where foreigners stood out among the crowd. But now, it is easy to see foreign communities scattered around the Seoul metropolitan area and outside the capital. There is even a prime time talk show solely dedicated to what foreign residents in Korea think about the country. With the growing number of foreign brides, migrant workers and foreign students, the number of foreign residents exceeded the 1 million mark as of August 2007. Considering that the number stood at a mere 40,000 in 1990, it is truly a dramatic change. Although multi-cultural Korean society is the fastest growing debate in the Korean society, there is a big lackness that deals on the muslim community or immigrant in Korea. According to immigration office data, among 1 million foreign immigrants in Korea, there are an estimated 104,427 Muslims living in Korea, occupying 10% of foreign residents. Considering the high birth rates among muslim immigrants and stagnated birth rates of Koreans, it is worthwhile to investigate muslim communities in Korea. Perhaps, it is the right time to research on Muslim immigrants in Korean society. Considering the mentioned above, this research focuses on the influx, adaptation, and social network of Muslim Immigrants in Korea as the first year subject of the government sponsored project on "Acculturation and Adaptation of Immigrant Muslims in Korean Society: Coexisting with Koslims(Korean-Muslims) in a Multi-Cultural Society". To investigate and to collect data from various muslim groups in Korea, this study divided the Koslims into five categories; Arab Muslims, non Arab Middle East Muslims, Central Asian Muslims, South Asian Muslims, and South East Asian Muslims. In order to outline the Muslim communities in Korea, initially, this research has employed various statistic data as qualitative method. However this study was done mainly through field research using survey method. Questionnaire and a face-to-face interview were used to explain the peculiarity of the different Muslim communities in Korea. Questionnaire and interview questions were prepared in 10 different languages. Collected data were carefully analyzed through SPSS program with cross tabulation and frequencies analysis. Based on fieldwork among Arab, non Arab Middle East, Central Asian, South Asian, and South East Asian Muslim communities in Korea, this article examines the present condition and social network of the Muslim immigrants in Korea. It investigates not only the general situation of the Koslims in Korea but also explores their adaptation and attitude toward the Korean community.

Cis-platin 내성 방광암세포주에 대한 Trichostatin A의 항암효과 분석

박지현(Jihyun Park),변석수(Seok-Soo Byun),이정은(Jeong Eun Lee),오종진(Jong Jin Oh),이상철(Sang Chul Lee),홍성규(Sung Kyu Hong),윤철용(Cheol Yong Yoon),이은식(Eunsik Lee),이상은(Sang Eun Lee) 대한비뇨기종양학회 2011 대한비뇨기종양학회지 Vol.9 No.2

Purpose: To determine anti-tumor effect of a histone deacetylase (HDAC) inhibitor, trichostatin A (TSA) in cis-platin resistant human bladder cancer cells (T24R2). Materials and Methods: T24 bladder cancer cell line and T24R2 were exposed to escalating dose of TSA and tumor cell proliferation was examined by CCK-8 assay. To evaluate the changes in cell cycle and apoptosis, flow cytometry was used and clonogenic assay was performed. Expression of p21WAF1/CIP1, cIAP1, XIAP, Bcl-2, and Bax were analyzed by Western blot. Results: Acute TSA administration (0.1-2μM for 24-72hours) suppressed tumor cell proliferation in a time- and dose-dependent manner (p<0.05) in all two bladder tumor cell lines. TSA induced G1 phase cell cycle arrest in both bladder cell lines and higher-fraction of sub-G1 (apoptotic portion) with 0.5μM in T24R2. A significant decrease in colony number was seen with the TSA treatment in the two cell lines. Western blot analysis revealed up-regulated p21 and bax, and down-regulated bcl-2, cIAP1 and xIAP with the increasing concentrations of TSA in both cell lines. Conclusions: Our results suggest anti-tumor effect of TSA in inhibiting bladder cancer growths and its potential role as an agent for treating cisplatin-resistant bladder cancer.