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Jones, Roy The Korean Society of Animal Reproduction 1999 Reproductive & developmental biology Vol.23 No.4
Four important attributes for successful fertilization by a spermatozoon are (ⅰ) correct morphology, (ⅱ) correct presentation of egg recognition and fusion molecules, (ⅲ) progressive motility and (ⅳ), correct transfer of signalling molecules from sperm to egg for activation of development. In this presentation, these topics will be described and illustrated with emphasis on the endogenous control mechanisms that enable spermatozoa to respond to external signals. (omitted)
The HadGEM2-ES implementation of CMIP5 centennial simulations
Jones, C. D.,Hughes, J. K.,Bellouin, N.,Hardiman, S. C.,Jones, G. S.,Knight, J.,Liddicoat, S.,O&,apos,Connor, F. M.,Andres, R. J.,Bell, C.,Boo, K.-O.,Bozzo, A.,Butchart, N.,Cadule, P.,Corbin, K. D. Copernicus GmbH 2011 Geoscientific model development Vol.4 No.3
<P><p><strong>Abstract.</strong> The scientific understanding of the Earth's climate system, including the central question of how the climate system is likely to respond to human-induced perturbations, is comprehensively captured in GCMs and Earth System Models (ESM). Diagnosing the simulated climate response, and comparing responses across different models, is crucially dependent on transparent assumptions of how the GCM/ESM has been driven - especially because the implementation can involve subjective decisions and may differ between modelling groups performing the same experiment. This paper outlines the climate forcings and setup of the Met Office Hadley Centre ESM, HadGEM2-ES for the CMIP5 set of centennial experiments. We document the prescribed greenhouse gas concentrations, aerosol precursors, stratospheric and tropospheric ozone assumptions, as well as implementation of land-use change and natural forcings for the HadGEM2-ES historical and future experiments following the Representative Concentration Pathways. In addition, we provide details of how HadGEM2-ES ensemble members were initialised from the control run and how the palaeoclimate and AMIP experiments, as well as the 'emission-driven' RCP experiments were performed.</p> </P>
Informed Consent for Scholarly Articles during the COVID-19 Pandemic
Jones Xaviar Michael,Zimba Olena,Gupta Latika 대한의학회 2021 Journal of Korean medical science Vol.36 No.3
The coronavirus disease 2019 pandemic has caused a breakdown in the healthcare system worldwide. The need to rapidly update guidelines in order to control the transmission in the population and for evidenced-based healthcare care has led to the need for timely, voluminous and valid research. Amid the quest for a vaccine and better therapies, researchers clamouring for information has led to a wide variety of ethical issues due to the unique situation. This paper aims to examine the positive and negative aspects of recent changes in the process of obtaining informed consent. The article outlines the various aspects, from history, previously described exemptions to consenting as well as those implemented during the pandemic and the current impact of virtual methods. Further, the authors make recommendations based on the outcome of suggested adjustments described in the literature. This article looks into increasing the awareness of physicians and researchers about ethical issues that need to be addressed to provide optimal care for patients while assuring their integrity and confidentiality.