Extrahepatic 90 Y Complication; Gastric Ulcer Secondary to 90 Y Therapy for Liver Metastasis Despite Negative Preprocedural Imaging

Connor Shea 대한핵의학회 2024 핵의학 분자영상 Vol.58 No.2

Transarterial radioembolization using yttrium-90 (90Y) therapy has become a standard modality of treatment for primary andmetastatic liver malignancies due to its high efficacy rate and relatively low risk of adverse effects compared to other formsof locoregional and systemic therapies. Non-target distribution of radio embolic beads and adjacent structure radiation arethe two most common adverse effects. However, these are rarely encountered due to thorough imaging and mapping studiesprior to 90Y therapy. We present the case of a 66-year-old male who developed a radiation-induced gastric ulcer following90Y therapy with negative pre-procedural imaging and mapping who was retrospectively found to have an accessory arteryfrom the left hepatic artery to the gastric antrum.

Rheological characterization of BCC and FCC structures in aqueous diblock copolymer liquid crystals

Connor S. Valentine,Lynn M. Walker 한국유변학회 2019 Korea-Australia rheology journal Vol.31 No.4

Low molecular weight, amphiphilic diblock copolymers in selective solvent exhibit complex phase behavior and macroscopic properties that affect the processing and application of these materials. The mechanical properties of the crystalline phases seen in concentrated solutions are dependent on nanoscale structure and sample history. The goal of this study is to characterize macroscopic properties and thermal history effects of lyotropic liquid crystals in aqueous diblock copolymer solutions. Rheological temperature ramps are used to characterize three aqueous concentrations of diblock copolymer [Brij-58®, C16H33(CH2CH2O)20OH]. Between these three samples the order-disorder transitions (ODTs) for BCC and FCC are accessible in addition to the order-order transition (OOT) between BCC and FCC. These transitions are distinguished using rheology. Frequency sweeps are performed across a range of temperatures and parameterized with a loglinear fit to the phase angle data to extract the crossover frequency. We find that a single frequency sweep does not distinguish BCC and FCC structures. By normalizing the temperature with respect to the ODT, we are able to use a series of frequency sweeps to distinguish characteristic trends in the response of BCC and FCC structures to thermal history.

유전적 개량에 적합한 미국선형심사체계의 가치

Connor, John P. 한국종축개량협회 2006 種畜改良 Vol.11 No.1

Tools to Prioritize Construction Phase Sustainability Actions (CPSAs) and to Measure CPSAs Implementation

O'Connor, James T.,Torres, Neftali,Kralik, Nancy,Woo, Jeyoung Korea Institute of Construction Engineering and Ma 2018 Journal of construction engineering and project ma Vol.8 No.1

Achieving sustainability targets on construction projects has increasingly become one of the prime strategies for construction organizations. To provide more detailed guidance on sustainability implementation on projects, Construction Industry Institute (CII) Research Team (RT) 304 developed a catalog of the Construction Phase Sustainability Actions (CPSAs). The primary objective of this paper was the development of two support tools, the CPSA Screening Tool and the CPSA Implementation Index, that could be used to enable efficient application of CPSAs, support sustainability-related decisions, and measure CPSA implementation and performance. The authors developed the tools in four stages: conceptual, detailed planning, tool programming, and testing. The tools were then demonstrated on a capital project to confirm their efficacy and applicability. This paper presents the background, inputs and outputs, and the algorithms of each tool. The CPSA Screening Tool can prioritize the CPSAs most relevant to a project; the CPSA Implementation Index enables continuous monitoring of implementation levels.

Sustainable in situ remediation of recalcitrant organic pollutants in groundwater with controlled release materials: A review

O'Connor, David,Hou, Deyi,Ok, Yong Sik,Song, Yinan,Sarmah, Ajit K.,Li, Xuanru,Tack, Filip M.G. Elsevier 2018 Journal of controlled release Vol.283 No.-

<P><B>Abstract</B></P> <P>The removal of recalcitrant organic pollutants in groundwater is a challenge being faced around the world. Achieving effective long-term remediation of contaminated aquifers faces a variety of significant issues such as back diffusion, tailing, and rebound. In recent years, some researchers have proposed the use of controlled release materials (CRMs) as a new approach to counteracting such issues. The novelty of CRMs lies in that they release their active products slowly, over prolonged periods of time, in order to sustain in situ treatments and long-term effectiveness. Here we review the main constituents of CRMs, analyze their production, characterization, and applications, with a focus on reaction mechanisms, effectiveness, and secondary effects. This review shows that the reactive components of CRMs most commonly involve either: (i) chemical oxidants to treat contaminants such as TCE, PCE, BTEX, and 1,4-Dioxane; (ii) sources of dissolved oxygen to stimulate aerobic biodegradation of contaminants such as BTEX and 1,4-Dioxane; or, (iii) substrates that stimulate reductive dechlorination of contaminants such as TCE and 1,2-DCA. It was found that in some studies, CRMs provided sustained delivery of CRM treatment reagents over several years, and achieved complete contaminant removal. However, lower removal rates were apparent in other cases, which may be ascribed to insufficient dispersion in the subsurface. There are a relatively limited number of field-scale applications of CRMs in contaminated land remediation. Those conducted to date suggest that CRMs could prove to be an effective future remediation strategy. Lessons learned from field applications, suggestions for future research directions, and conclusions are put forward in this review.</P> <P><B>Highlights</B></P> <P> <UL> <LI> Long-term remediation of groundwater remains very challenging. </LI> <LI> Researchers have proposed the use of a variety of controlled release materials. </LI> <LI> They can release chemical oxidants, sources of dissolved oxygen, or substrates. </LI> <LI> Some controlled release materials can sustain reagent release for several years. </LI> <LI> Future research needs are put forward to help further develop these materials. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

아동학대 중재시 고려사항

KevinO'Connor,손명희 한국아동심리재활학회 2003 놀이치료연구 Vol.7 No.2

Stretchable, Implantable, Nanostructured Flow-Diverter System for Quantification of Intra-aneurysmal Hemodynamics

Howe, Connor,Mishra, Saswat,Kim, Yun-Soung,Chen, Yanfei,Ye, Sang-Ho,Wagner, William R.,Jeong, Jae-Woong,Byun, Hun-Soo,Kim, Jong-Hoon,Chun, Youngjae,Yeo, Woon-Hong American Chemical Society 2018 ACS NANO Vol.12 No.8

<P>Random weakening of an intracranial blood vessel results in abnormal blood flow into an aneurysmal sac. Recent advancements show that an implantable flow diverter, integrated with a medical stent, enables a highly effective treatment of cerebral aneurysms by guiding blood flow into the normal vessel path. None of such treatment systems, however, offers post-treatment monitoring to assess the progress of sac occlusion. Therefore, physicians rely heavily on either angiography or magnetic resonance imaging. Both methods require a dedicated facility with sophisticated equipment settings and time-consuming, cumbersome procedures. In this paper, we introduce an implantable, stretchable, nanostructured flow-sensor system for quantification of intra-aneurysmal hemodynamics. The open-mesh membrane device is capable of effective implantation in complex neurovascular vessels with extreme stretchability (500% radial stretching) and bendability (180° with 0.75 mm radius of curvature) for monitoring of the treatment progress. A collection of quantitative mechanics, fluid dynamics, and experimental studies establish the fundamental aspects of design criteria for a highly compliant, implantable device. Hemocompatibility study using fresh ovine blood captures the device feasibility for long-term insertion in a blood vessel, showing less platelet deposition compared to that in existing implantable materials. <I>In vitro</I> demonstrations of three types of flow sensors show quantification of intra-aneurysmal blood flow in a pig aorta and the capability of observation of aneurysm treatment with a great sensitivity (detection limit as small as 0.032 m/s). Overall, this work describes a mechanically soft flow-diverter system that offers an effective treatment of aneurysms with an active monitoring of intra-aneurysmal hemodynamics.</P> [FIG OMISSION]</BR>

정보요구에 관한 문제점

O'Connor, J. 한국과학기술정보연구원 과학기술정보센터 1974 Journal of Information Science Theory and Practice Vol.7 No.3

INTERCOMM 93 - 아시아 태평양 지역의 기업 정보 통신망의 발전

O'Connor Maurie 한국정보통신기술협회 1993 국제전기통신표준화소식 Vol.27 No.-

The Impact of Ashwagandha on Stress, Sleep Quality, and Food Cravings in College Students: Quantitative Analysis of a Double-Blind Randomized Control Trial

Jack O’Connor,Keston Lindsay,Cynthia Baker,Jessica Kirby,Andrea Hutchins,Margaret Harris 한국식품영양과학회 2022 Journal of medicinal food Vol.25 No.12

The purpose of this study was to examine the impact of ashwagandha (ASH) (Withania somnifera) on sleep, perceived stress, and cravings in a college student population. Sixty healthy students were screened/enrolled into a 30-day double-blinded placebo (PLA)-controlled intervention (700 mg daily, full spectrum extract of ASH root). Anthropometrics, demographics, and validated questionnaires assessing physical activity, restorative sleep, perceived stress, and food cravings were assessed before and after the study. Descriptive statistics, Pearson's correlations, and point biserial correlations were used to screen the data. For sleep and stress, a nonsignificant mixed (group × time) multivariate analysis of variance (MANOVA) was followed by one-way MANOVA (time on sleep/stress) and one-way multivariate analysis of covariance (MANCOVA) (group on sleep/stress, using initial sleep as a covariate) as follow-up tests. Further follow-up tests for this MANCOVA showed group membership affected final sleep (58.4 ± 12.4 vs. 48.2 ± 15.0 ASH vs. PLA respectively, P < .05) using initial sleep as a covariate. Initial sleep (confounder) affected final stress, but not final sleep. Mixed analysis of variance (group × time) showed an interaction effect on food cravings, where the ASH group experienced lower cravings than the PLA group over time at end of study. The 30-day intervention was shorter than most other studies where more pronounced stress differences were seen at six weeks, indicating ASH may need the longer time period to show more pronounced stress relieving differences. ASH can be an effective safe intervention in young adult populations to help manage stress and its detrimental impacts on sleep and satiety in as little as 30 days. Clinical Trial Registration number-NCT05430685.