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RISS 인기검색어
- 검색키워드
- 저자 : John Moraes (검색결과 3 건)
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Nano-structured silicas and silicates-new materials and their applications in paper
James H.,John Moraes,Andrew J.,Thomas 한국물리학회 2004 Current Applied Physics Vol.4 No.2-4
Nano-structured silica with an open network structure has been produced bycontrolled precipitation from geothermal water.The material has a pore volume, as measured bythe oil absorption capacityof about 200250 g oil. 100 g. 1 silica, and the surfacearea is about 5060 m2 g. 1. It has been used as a ller in newsprint and the technologyhas been developed on a laboratoryscale and progressed to pilot plant production with full scale paper mill manufacturing and commercial printing trials. Print through reductions of 30% for newsprint and 40% for yellow directory grade paper were achieved. Nano-structured calcium silicate with anopen framework structure has been formed from sodium silicate solution. This product has a verylarge pore volume of about 300-550 g oil. 100 g-1 silicate and a large surface area of about 350600 m2 g. 1 depending upon the synthesis method. It has been testedas a ller in newsprint on a laboratoryscale and reduced print through byabout 40% for 55 gsm newsprint and byabout 53% for 45gsm newsprint. The material is better than nano-structured silica for this application and it substantially outperforms calcined clay.
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Conducting polymer composites with cellulose and protein fibres
James H. Johnston,John Moraes,Thomas Borrmann,David Flynn,Fern M. Kelly 한국물리학회 2006 Current Applied Physics Vol.6 No.3
Conducting polymer–fibre composites with polypyrrole cellulose (paper) and protein (wool) fibres have been produced by polymerizing pyrrole with ferric chloride as the oxidant around separated individual cellulose (wood) fibres from bleached Pinus radiata Kraft pulp, and merino wool fibres respectively to generate new composite materials that retain the inherent properties of the polymer and individual fibres. For the polypyrrole–cellulose composite, the polypyrrole consisted of spheres of about 100 nm in size fused together to form a continuous coating that fully encapsulates the cellulose fibre and associated finer fibrils. For the polypyrrole–wool composite the polypyrrole formed a similar coating of about 200 nm spheres. Electrical conductivities of the composites were substantially increased over those of the precursor fibres.
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Mesenchymal stem cells reduce ER stress via PERK-Nrf2 pathway in an aged mouse model
이은주,( Nayra Cárdenes ),( Diana Álvarez ),( Jacobo Sellares ),( John Sembrat ),( Paola Aranda ),( Yating Peng ),( Jordan Bullock ),( Seyed Mehdi Nouraie ),( Ana L Mora ),( Mauricio Rojas ) 대한결핵 및 호흡기학회 2018 대한결핵 및 호흡기학회 추계학술대회 초록집 Vol.126 No.-
Mesenchymal stem cells (MSCs) have been shown to ameliorate the deleterious effects of bleomycin. However, the mechanism responsible for protection of stem cell therapy in pulmonary fibrosis is still poorly understood, especially in terms of the endoplasmic reticulum (ER) stress. We hypothesized that ER stress could increase after a certain time elapse and then decrease to the baseline, resembling the fibrosis after bleomycin exposure. We also attempted to clarify the exact role of MSCs upon ER stress by a timely sacrifice of animals at the peak of ER stress. In order to determine the peak time in ER stress, the expression of ER stress marker proteins after bleomycin injury were measured in the lung of old mice at different time points (day 0, 3, 7, 14, and 21). For evaluation of the effect of MSCs on ER stress, we assessed the bleomycin insult by changes in body weight, lung tissues histology and the protein expression of ER stress markers. The level of expression of unfolded protein response (UPR) transcription factor XBP-1 and its regulator BiP were elevated at day 7 and progressively increased up to day 21. MSCs inhibited BiP expression in bleomycin-induced ER stress, whereas the expression levels of other ER stress markers were not reduced by MSCs. MSCs operate on ER stress via several pathways, but the PERK-Nrf2 pathway revealed to be the main functioning pathway. In conclusion, we demonstrated that MSCs attenuate ER stress via PERK-Nrf2 pathway.
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