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Jin Yang,Lei Cai,Sen Zhang,Xiangjia Zhu,Peng Zhou,Yi Lu 대한약학회 2014 Archives of Pharmacal Research Vol.37 No.3
This study aimed to investigate whether silicacerium(III) chloride (CeCl3) nanoparticles could inhibitthe formation of advanced glycation end-products (AGEs)and reduce oxidative stress. Silica-CeCl3 nanoparticleswere synthesised by adsorption and embedment withmicro-silica materials, forming uniform nanoparticles witha diameter of approximately 130 nm. Chaperone activityassays and AGEs formation assays, and intracellular reactiveassays were adopted in this study to evaluate CeCl3nanoparticles effect. UV–visible spectrometry showed thatsilica-CeCl3 nanoparticles at low concentrations rapidlyformed tentatively stable conjugations with a-crystallin,greatly enhancing the chaperone activity of a-crystallin. Moreover, silica-CeCl3 nanoparticles markedly inhibitedthe fructose-induced glycation of a-crystallin, showing anadvantage over the control drugs aminoguanidine andcarnosine. Silica-CeCl3 nanoparticles also reduced intracellularreactive oxygen species production and restoredglutathione levels in H2O2-treated human lens epithelialcells. These findings suggest that silica-CeCl3 may be usedas a novel agent for the prevention of cataractogenesis.
Lei Deng,Peng Zhou,Xinyun Wang,Junsong Jin,Ting Zhao 대한금속·재료학회 2018 METALS AND MATERIALS International Vol.24 No.1
In this work, specimens of the 2024 aluminum alloy sheet were compressed and stretched along the original rollingdirection at elevated temperatures. The microstructure evolution was investigated by characterizing the metallographicstructures via electron backscattered diffraction technology before and after deformation. It was foundthat while recrystallization occurred in the compressed specimens, it was not observed to the same extent in thestretched specimens. This difference in the grain morphology has been attributed to the different movement behaviorsof the grain boundaries, i.e., their significant migration in the compression deformation and the transformationfrom low-angle to high-angle boundaries observed mainly during tension deformation. The empirical model,which can describe the grain size evolution during compression, is not suitable in the case of tension, and therefore,a new model which ignores the detailed recrystallization process has been proposed. This model provides adescription of the grain size change during hot deformation and can be used to predict the grain size in the plasticdeformation process.
Robust Object Tracking with Mutualism between Particle Filter and Geometric Active Contour
Lei Sun,Sun-an Wang,Jin-hua Zhang,Xiao-hu Li 보안공학연구지원센터 2015 International Journal of Signal Processing, Image Vol.8 No.12
Robust object tracking is important in many real applications. This study proposes a novel robust object tracking algorithm that combines particle filter and geometric active contour. In contrast to conventional combinations, the proposed algorithm establishes mutualism, wherein the particle filter provides curve initialization for the active contour by using the alpha shape algorithm, and the active contour provides evolved boundary for particle filter classification. The refined particles are used to estimate the states which reduce the distance error. Discriminable object feature is proposed to enhance the tracking robustness, and prior information-based curve evolution is used to improve the accuracy of boundary segmentation. Comparable experiments are performed using a stand particle filter and continuously adaptive mean-shift methods. The proposed algorithm is found to be highly robust for long video sequences with non-linear motion, scale changes and clutter background.