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침습성 거대프로락틴분비종양으로 발현된 다발내분비샘종양1형 1예
차진훈 ( Jinhoon Cha ),김진서 ( Jin Seo Kim ),한정석 ( Jung Suk Han ),박연원 ( Yeon Won Park ),김민주 ( Min Joo Kim ),구윤희 ( Yun Hyi Ku ),김홍일 ( Hong Il Kim ) 대한내과학회 2016 대한내과학회지 Vol.91 No.3
Pituitary tumors occur in 15-50% of patients with multiple endocrine neoplasia of type 1 (MEN1). To the best of our knowledge, no MEN1 case in which the initial lesion was an invasive giant prolactinoma has been reported from Korea. We describe a patient in whom a skull-base tumor involved the sellar and parasellar spaces. A 49 year-old female presented with headache and diplopia. The tumor was ultimately identified as a giant prolactinoma; the serum prolactin concentration increased from 155.6 ng/mL to 3,234.3 ng/mL after cranial irradiation. She was evaluated in terms of incidental hypercalcemia and was found to have parathyroid hyperplasia. Genetic analysis revealed a missense mutation in the MEN1 gene (c.643G>A, p.Val215Met). Two years of treatment with a dopamine agonist reduced, but did not normalize, the serum prolactin concentration. We highlight the aggressive behavior of the giant skull-base tumor, and the diagnostic delay caused by a high-dose hook effect of the MEN1-related prolactinoma. (Korean J Med 2016;91:300-305)
게임의 몰입을 위한 배경 컨셉 디자인 연구: 「젤다의 전설_야생의 숨결」을 중심으로
김진훈 ( Jinhoon Kim ) 한국창의정보문화학회 2023 창의정보문화연구 Vol.9 No.2
본 연구는 미하이 칙센트미하이의 몰입이론을 기반으로 게임의 몰입구조를 규정하였다. 배경 그래픽이 게임의 몰입 과정의 한 축을 담당하는 것을 확인했으며, 배경 컨셉 디자인의 세계관 표현 및 구성 방법을 분석하였다. 「젤다의 전설_야생의 숨결」의 마을들의 배경 컨셉 디자인을 분석하여 배경 그래픽이 정보제공의 역할과 스토리텔링 도구의 역할을 하는 것을 알게 되었다. 이를 통해 사용자들은 인지 부하를 감소시키고 게임내 스토리와 감정에 몰입할 수 있을 것으로 분석된다. 연구 결과, 일관된 표현 규칙과 직관적인 디자인을 통해 세계관 컨셉 설정을 충실히 재현한 배경 컨셉 디자인은 사용자가 다양한 배경 그래픽 속에서 게임의 목표를 달성할 수 있도록 정보를 명확하게 전달할 수 있다. 또한, 시각적으로 스토리를 연상시키는 배경 컨셉 디자인은 스토리텔링을 가능케 해 더욱 풍부한 몰입 경험을 제공할 수 있을 것이다. This study defined the immersion structure of the game based on Mihaly Csikszentmihalyi's theory of flow. It was confirmed that background graphics play an axis in the game's immersion process, and the expression and composition of the worldview of the background concept design were analyzed. By analyzing the background concept designs of the villages in 「The Legend of Zelda: Breath of the Wild」, we learned that background graphics serve as information provision and storytelling tools. Through this, it is analyzed that users will be able to reduce cognitive load and immerse themselves in stories and emotions in the game. As a result of the study, the background concept design, which faithfully reproduces the worldview concept setting through consistent expression rules and intuitive design, can clearly convey information so that users can achieve the goal of the game in various background graphics. In addition, the background concept design visually reminiscent of the story will enable storytelling to provide a richer immersion experience.
현상적 수트 모델을 이용한 디젤 엔진의 분할 분사에 관한 연구
김진훈(Jinhoon Kim),김병룡(Byungyong Kim),성낙원(Nakwon Sung) 한국자동차공학회 2002 한국자동차공학회 춘 추계 학술대회 논문집 Vol.2002 No.5_1
Some studies have been reported that split injections are effective for reducing soot. This study was conducted to understand how split injection affects the soot emission in a direct injection diesel engine by using a phenomenological model of soot formation. In the model of soot formation, major generic processes are included such as the formation of soot precursors, formation of surface growth species, soot particle nucleation, coagulation, surface growth and oxidation. It consisted of four differential equations balancing the rates of change of soot precursor radicals, soot growth species, and particle number density. Arrhenius type global kinetic rate expressions were written for the most of the processes. The model was implanted into the modified KIVA-3V code. The results showed that split injection reduced soot emissions in all calcuation cases.