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Wang, Xiao,Fan, Jin-Chuan,Wang, An-Rong,Leng, Yue,Li, Jun,Bao, Yu,Wang, Ying,Yang, Qing-Feng,Ren, Yu Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.4
Background and Objectives: Yanting in Sichuan Province is one of the highest risk areas of esophageal cancer (EC) in the world. We here summarize the epidemiology of EC in Yanting using data from the national screening programme during 2006-2011. Methods: Random cluster sampling was used to select a proportion of natural villages from six towns in Yanting, and residents aged 40-69 years old were invited for screening. Participants were screened using endoscopy with iodine staining and then confirmed by histological examinations. Results: The overall detection rates of low-grade hyperplasia (LH), moderate hyperplasia (MH), high-grade hyperplasia (HH), carcinoma in situ (CIS), intramucosal carcinoma (IC) and invasive carcinoma (INC) were 5.33%, 1.28%, 0.68%, 0.15%, 0.06% and 0.29%, respectively. The detection rates of LH, MH, HH and INC increased with age, reaching the peak among those aged 60-65 years, and the prevalences of LH and MH were higher among men than among women. In addition, the detection rates of hyperplasia were much higher in mountainous than in hilly areas. Conclusions: Among the high risk population, there are a great number of people with early-stage EC or precancerous conditions who do not have presenting symptoms. In particular, the elderly, men, or those living in mountainous areas are the most vulnerable population. It is therefore important to reinforce health education and screening services among such high risk populations.
Diagnostic Value of Superoxide Dismutase in Tuberculous and Malignant Pleural Effusions
Wang, Xin-Feng,Wu, Yan-Hua,Jiao, Jin,Guan, Cui-Ping,Yang, Xiao-Guang,Wang, Mao-Shui Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
The aim of this study was to investigate the diagnostic value of superoxide dismutase (SOD) in tuberculous pleural effusions (TPEs) and malignant pleural effusions (MPEs). Pleural effusion (PE) samples from 100 patients were classified on the basis of diagnosis as TPE (n=57) and MPE (n=43). The activity of SOD was determined by pyrolgallol assay. A significant difference was observed in SOD activity (P<0.01) between TPE and MPE, levels of being significantly higher in TPE compared to MPE. With a threshold value of 41 U/L, the area under the ROC curve was 0.653, SOD had a sensitivity of 61.4% and a specificity of 61.0% for differential diagnosis. Thus, SOD activity in PE was not a good biomarker in differentiating TPE and MPE. To the best of our knowledge, five SOD isoforms may be present in PE. Identification of which SOD contributes to the difference of SOD level between TPE and MPE is very important for illustrating mechanisms and improving the differential diagnostic value.
Security Threats among DICOM Imaging Communications in Public Networks
Feng Zhou,Zhongqi Zhang,Jin Wang,Bin Li,Jeong-Uk Kim 보안공학연구지원센터 2014 International Journal of Future Generation Communi Vol.7 No.6
Picture archiving and communication systems (PACS) require high-speed networks to transmit large image files between components. Image-data transmission from one site to another through public network is usually characterized in term of privacy, authenticity, and integrity. However, public network’s security issues had always been the significant problems. Recent years, IPv6 brings significant improvements in mechanisms for assuring a higher level of security and confidentiality of the transmitted information. Thus, it is still necessary to take care of some particular aspects. In this paper, we first analyzes how actual security threats and different types of attacks affect IPv6 networks while transmitting Digital Imaging and Communications in Medicine (DICOM) files through the public Internet. Second, illustrate some shortcomings of IPv6 and IPv6’s traffic loads. Finally, some possible solutions against a number of security threats in IPv6 DICOM files transmitting networks have been given.
Temporary Shear Brace Design Method for Steel Box Girder Viaduct in Transverse Block Construction
Jin-feng Wang,Min-quan Wang,Yu-bing Zhou,Xi Wu 한국강구조학회 2018 International Journal of Steel Structures Vol.18 No.3
Transverse block of a steel box girder viaduct can decrease the shear connection between the upper part and the lower part. As a consequence, defl ection and defl ection diff erence between blocks are signifi cant, and the performance of weld seams and fi nished viaduct can be aff ected. To decrease the defl ection of steel box blocks with an open section after transverse discretization, a piecewise uniform arrangement of temporary shear braces is proposed on condition that the total shear stiff - ness of the shear braces remains unchanged. First, the formulas for slip, axial force and defl ection with a piecewise uniform arrangement of temporary shear braces are given, and the accuracy is verifi ed by comparing the results with fi nite element method. The proposed formulas are applied to two fi eld studies and the results show good agreement with measured data. Finally, the optimal arrangement of temporary shear braces was explored by the sequential quadratic programming optimization method. The defl ection and the defl ection diff erence at welding position are reduced signifi cantly after bracing, and the optimal shear braces arrangement is to arrange the braces more at the ends of the blocks.
Double Validation Multi Level Proxy Blind Signature Scheme Key Management
Wang Jin-feng 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.10
Identity-based signature (IBS) scheme can be widely used in resource-limited situations such as mobile e-commerce. In this paper, a lattice-based IBS scheme is first established by using trapdoor generation algorithm GenTrap, preimage sample algorithm SampleD and trapdoor delegated algorithm DelTrap put forward by Micciancio and Peikert in Eurocrypt’12; then the proposed scheme is proven to satisfy strong unforgeability against selective ID and static chosen massage attack in the standard model based on small integer solutions (SIS); and finally the proposed scheme is compared with the existing similar scheme in computing performance. The results show that the scheme presented in this paper enjoys the highest efficiency.
Menglong Wang,Lan Jiang,Qingen Da,Jun Liu,Dongru Feng,Jinfa Wang,Hong-Bin Wang,Hong-Lei Jin 한국식물학회 2017 Journal of Plant Biology Vol.60 No.6
Plastid-encoded plastid RNA polymerase (PEP) isessential for chloroplast development and plastid geneexpression in Arabidopsis thaliana. However, PEP is a largecomplex, and many proteins in this complex remain to beidentified. We previously reported that Delayed Greening238 (DG238) interacts with PEP subunit protein FLN1 andmay function as a PEP-associated protein and participate inearly chloroplast development and PEP-dependent plastidgene expression. DG238 contains Domain of UnknownFunction 143 (DUF143), whose function is currently unknown. Here, we found that a deficiency of the DUF143 domain inDG238 affected its localization, which resulted in abnormalinteractions with PEP-associated proteins in the chloroplast. Furthermore, DG238 lacking the DUF143 domain or DG238with only this domain failed to function. Interestingly, thelack of conserved amino acids 193–217 of the DUF143domain in DG238 also affected its function. In addition toFLN1, DG238 also interacts with other PEP-associatedproteins, including FSD2, FSD3, MRL7-L, and MRL7, toregulate plastid gene expression. These results suggest thatthe DUF143 domain is necessary for the functioning of thePEP-associated protein DG238 in chloroplasts.
Xiang-Feng Wu,Yi-Jin Wang,Zuo-Lin Cao,Yan-Mei Feng,Hui Li,Chen-Xu Zhang,Jun-Zhang Su,Jia-Rui Zhang,Yi-Wei Wang,Kai-Yuan Wang,Guo-Wen Sun 대한화학회 2018 Bulletin of the Korean Chemical Society Vol.39 No.7
The novel AgCl/Ag2SO3 hybrids as an efficient photocatalyst had been fabricated by an in situ synthetic method. The correlations between the structure and the photocatalytic properties of the as-fabricated hybrids were analyzed. Experimental results exhibited that with increasing the amount of Ag2SO3, the degradation rate of the as-obtained samples was firstly increased and then decreased under the visible light irradiation. When the mass ratio of AgCl to Ag2SO3 was 1:2, in 30?min, it displayed the highest degradation rate of 99.2% for rhodamine-B, which was obviously higher than 46.1, 60.5, and 14.6% of pure AgCl, Ag2SO3, and TiO2 (P25), respectively. Similar results could be found in degradation of methyl orange. It had the maximum of 97.4% in 90?min, which was higher than 55.2, 48.7, and 12.7% of pure AgCl, Ag2SO3, and P25, respectively. Moreover, the as-prepared hybrids possessed the enhanced separation and transfer of photo-generated electron?hole pairs compared to the pure samples. In addition, the holes and superoxide radicals played the dominant role and the hydroxyl radicals played the secondary role during the process of photocatalytic degradation.
Review of the Molecular Pathogenesis of Osteosarcoma
He, Jin-Peng,Hao, Yun,Wang, Xiao-Lin,Yang, Xiao-Jin,Shao, Jing-Fan,Guo, Feng-Jin,Feng, Jie-Xiong Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.15
Treating the osteosarcoma (OSA) remains a challenge. Current strategies focus on the primary tumor and have limited efficacy for metastatic OSA. A better understanding of the OSA pathogenesis may provide a rational basis for innovative treatment strategies especially for metastases. The aim of this review is to give an overview of the molecular mechanisms of OSA tumorigenesis, OSA cell proliferation, apoptosis, migration, and chemotherapy resistance, and how improved understanding might contribute to designing a better treatment target for OSA.