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Jimin Yoo,Dong Jae Shim,Doyoung Kim,Seung Hwan Baek,Chang Suk Park,Jeong Whee Lee 대한영상의학회 2023 대한영상의학회지 Vol.84 No.2
The subclavian vein is an uncommon route for tunneled hemodialysis catheter (tHDC) placement because of its potency for future dialysis access. However, when favored access routes have been exhausted because of repeated catheterization or limited life expectancy, the subclavian vein can be used for urgent hemodialysis. A subclavian catheterization has a technical problem. The subclavian vein often forms a right angle with the vena cava, and advancing stiff peel-away sheath can cause a vascular injury. However, raising the patient’s arm can alter the position of the guidewire and, therefore, change the angle of the vein favorable for tHDC placement. Herein, we report two patients who underwent subclavian catheterization; one experienced an injury to the superior vena cava after undergoing the conventional procedure, whereas the other patient with raised arm during the catheterization procedure had safe catheter placement.
유지민(Jimin Yoo),김소영(Soyoung Kim),조은아(Eun-ah Cho),조은혜(Eunhye Cho),최선주(Sunju Choi),정윤주(Yoonjoo Jeong),하병집(Byungjhip Ha),채희정(Hee Jeong Chae) 한국생물공학회 2010 KSBB Journal Vol.25 No.2
본 연구에서는 이중결합을 가진 불포화화합물로 제조나저장 시 열과 산화 (빛)에 의해 쉽게 파괴되어 활성이 감소하여 응용범위에 한계가 있는 아스타잔틴의 안정성 향상을 위하여 나노리포좀 제형기술을 이용하였다. 제형안정성 평가를 통하여 리포좀 제조조건 및 조성비를 확립하였고, 포접나노리포좀을 제조하여 포접전의 아스타잔틴과 안정성을 비교 검토하였다. 아스타잔틴을 포접하여 포접나노리포좀 제조 시포접전의 아스타잔틴에 비해 열에 대한 안정성이 2배 정도 향상되고, UV 안정성 또한 3배 향상된 것을 확인하였다. 이상의 결과로부터 아스타잔틴을 포접한 포접나노리포좀은 안정성이 우수한 기능성 원료로서 산업적으로 용도를 넓히고 부가가치를 더욱 향상시킬 수 있을 것으로 기대된다. Astaxanthin is an unsaturated compound with a double bond. So it is easily decayed by heat and oxidation (light) during its storage and processing of it. Nanoliposome formulation technology was utilized to improve the stability of astaxanthin. Nanoliposome preparation conditions were established and the stability of astaxanthin encapsulated nanoliposome and free astaxanthin was investigated. Thermal stability and UV-stability of astaxanthin encapsulated nanoliposome increased up to two times and tree times, respectively. Astaxanthin encapsulated nanoliposome could be used as a stable functional material for industrial purposes.
( Jimin Cha ),( Sung Jong Lee ),( In Cheul Jeong ),( Ji Keun Yoo ),( Eun Young Ki ) 대한산부인과학회 2022 대한산부인과학회 학술대회 Vol.108 No.-
Objective: The aim of this study was to evaluate the clinical performance between the cobas4800 HPV test (test1) and the PANA RealTyperTM HPV screening kit assay (test2) for the detection of high risk human papillomavirus(HPV) in a clinical setting. Methods: Cervical swab specimens for cytologic exam or HPV test were obtained from a total of 541 women at Seoul St. Marys Hospital between October 2017 and February 2019. We performed the 2 tests to detect HPV. If the results differ from each other, PCR and direct sequencing was conducted. Results: The overall concordance rate between the 2 tests was 94.0% for the detection of high risk(HR) HPV. Between the 2 tests, the positive concordance was 83.8% and negative concordance was 97.9%( value= 0.83) for the detection of HPV 16. Also, the positive concordance was 94.7%, and the negative concordance was 99.4% ( value= 0.95) for the detection of HPV 18. The sensitivity and specificity of test 2 for the detection of HPV 16 were 97.1%(95% CI, 90.9-98.4) and 98.7%(95% CI, 97.3-99.3), respectively, those of HPV 18 were 100% (95% CI, 97.1-97.7) and 99.6%(95% CI, 98.6-99.8), respectively. The sensitivity and specificity of test 1 for the detection of HPV 16 were 94.2% (95% CI, 86.6-97.1) and 97.7% (95% CI, 95.9-98.6), respectively, those of HPV 18 were 100% (95% CI, 97.1-97.7) and 99.2% (95% CI, 97.9-99.6), respectively. Conclusion: This showed that the concordance rate between the 2 tests was significantly high and that the 2 tests similarly detected HR HPV. Test 2 can be used to detect high risk HPV in clinical practice.
A Single-Chip CMOS Smoke and Temperature Sensor for an Intelligent Fire Detector
Jimin Cheon,Jeonghwan Lee,Inhee Lee,Youngcheol Chae,Youngsin Yoo,Gunhee Han IEEE 2009 IEEE SENSORS JOURNAL Vol.9 No.8
<P>A single-chip CMOS smoke and temperature sensor for use as an intelligent fire detector is proposed. The proposed smoke sensor measures smoke density based on the light-scattering method. The temperature sensor is integrated with the smoke sensor not only to sense heat from a fire but also to compensate for the temperature dependency of the smoke sensor. The prototype chip includes an on-chip photodiode (PD), pixel circuit, correlated double sampling (CDS) circuit, and analog-to-digital converter (ADC). The prototype chip was fabricated using a 0.35-mu m CMOS process and was placed inside the smoke detection chamber, while the thermistor for the temperature sensor is placed outside the chamber. The measurement results show plusmn 1% smoke detection accuracy over the range 4% ~ 25% and plusmn1degC temperature-sensing accuracy over the range 25degC ~ 95degC. The power consumption of the prototype chip is 220 nW, excluding the infrared light-emitting diode (IR LED).</P>
DSigDB: drug signatures database for gene set analysis
Yoo, Minjae,Shin, Jimin,Kim, Jihye,Ryall, Karen A.,Lee, Kyubum,Lee, Sunwon,Jeon, Minji,Kang, Jaewoo,Tan, Aik Choon Oxford University Press 2015 Bioinformatics Vol.31 No.18
<P><B>Summary:</B> We report the creation of Drug Signatures Database (DSigDB), a new gene set resource that relates drugs/compounds and their target genes, for gene set enrichment analysis (GSEA). DSigDB currently holds 22 527 gene sets, consists of 17 389 unique compounds covering 19 531 genes. We also developed an online DSigDB resource that allows users to search, view and download drugs/compounds and gene sets. DSigDB gene sets provide seamless integration to GSEA software for linking gene expressions with drugs/compounds for drug repurposing and translational research.</P><P><B>Availability and implementation:</B> DSigDB is freely available for non-commercial use at http://tanlab.ucdenver.edu/DSigDB.</P><P><B>Supplementary information:</B> Supplementary data are available at <I>Bioinformatics</I> online.</P><P><B>Contact:</B> aikchoon.tan@ucdenver.edu</P>
이지민 ( Jimin Lee ),오윤경 ( Yun-gyeong Oh ),유승환 ( Seung-hwan Yoo ),최수명 ( Soo-myoung Choi ) 한국농공학회 2017 한국농공학회 학술대회초록집 Vol.2017 No.-
농업기반정비는 농지의 효율적 이용을 위해 농지의 집담화, 규모화를 꾸준히 진행하여 왔다. 그러나 지형적 한계, 소유자의 이해관계 등으로 한계가 존재하였다. 한편 ICT와 IoT의 발달을 통해 시설농업의 자동화뿐만 아니라 작물의 생산, 수확, 유통 등 전 단계에서 기계화, 자동화가 도입되고 있다. 이러한 농업의 첨단화 과정에도 농지의 파편화된 공간적 특징은 제약으로 작용한다. 본 연구에서는 농지이 파편화 정도를 분석하기 위해 전라남도 14개 시군을 대상으로 농지의 공간적 분포현황과 농업경영체별 농지의 분포를 분석하였다. 분석에는 농업경영체 DB와 지적도를 결합한 농업경영체 농지현황도를 사용하였다. 공간분석을 위해서는 경관지수 분석 프로그램인 Fragstats을 이용하여 Class 레벨(경영체별 현황)과 Landscape 레벨(시·군내 농지 전체 현황) 분석을 실시하였으며 그 결과를 비교하였다. 지역별 비교에는 먼저 광주광역시를 인접하고 있는 6개 시군과 그렇지 않은 8개 시군을 구분하여 비교하였다. Landscape 레벨에서 파편화 정도를 나타내는 경관지수 LPI와 LSI를 비교한 결과, 그룹별 비교에서는 광주인접 시군이 그렇지 않은 시군보다 LPI값이 낮고 LSI값이 높아 농지의 파편화 정도가 큰 것으로 나타났다. 지역별로 살펴보면, 영암군의 LPI값이 가장 낮게 나타났으며, 순천시가 가장 큰 LSI값을 가지고 있었다. Class레벨에서는 지역별 평균값을 비교했을 때, 구례군, 해남군, 곡성군이 다른 지역보다 큰 CA값을 가졌으며, 함평군, 해남군, 영암군이 낮은 COHESION값을 보여 공간적 응집이 낮은 것으로 나타났다. 향후 이러한 농지의 파편화정도 분석기법은 농업기반정비의 전후 결과의 비교, 정비계획의 수립에 활용될 수 있을 것이다.