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- 저자 : Jianan Zhou (검색결과 5 건)
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Microstructure and Mechanical Properties of Mg–2.0Gd–1.2Y–1.0Zn–0.2Zr Alloy
Jianan Liu,Xiaoru Zhang,Wenxue Lv,Yumei Zhou,Daqing Fang,Xiangdong Ding,Jun Sun 대한금속·재료학회 2021 METALS AND MATERIALS International Vol.27 No.7
The microstructural evolution of Mg–2.0Gd–1.2Y–1.0Zn–0.2Zr (GWZK) alloy during homogenization and subsequentaging heat-treatment and the tensile properties of the peak-aged sample at various temperatures have been investigated. Thephase transformation during homogenization, static precipitation during aging, and deformation mechanisms at 250 °C aresystematically analyzed through XRD, TEM and EBSD measurements. The peak-aged GWZK alloy has good combinationof strength and ductility at elevated temperatures owing to its high thermal stability by the LPSO phases distributed alongthe grain boundaries. The change (19 MPa) in the yield strength of peak-aged samples between RT and 250 °C is mainlyrelated to easy gliding of dislocations on the non-basal planes due to the decrease in critical resolved shear stress of slip. Two strengthening models are applied to quantitatively describe the efect of {11 −2 0}훼precipitate plates on Orowanstrengthening corresponding to RT and 250 °C. Ignoring changes in solid solution strengthening and grain boundary strengthening of the peak-aged sample caused by increasing temperature, the calculated reduction value (16.5 MPa) in macroscopicyield strength from RT (based on the basal<a>slip mode) to 250 °C (based on the pyramidal<c+a>slip mode) is in goodagreement with the measured reduction value (19 MPa).
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Identification of a mimotope of an infectious bronchitis virus S1 protein
Jingming Zhou,Jianan Li,Yanghui Li,Hongliang Liu,Yanhua Qi,Aiping Wang 대한수의학회 2021 Journal of Veterinary Science Vol.22 No.4
The S1 protein of the infectious bronchitis virus (IBV) is a major structural protein that induces the production of the virus-neutralization antibodies. The monoclonal antibody against the IBV M41 S1 protein was used as a target for biopanning. After three rounds of biopanning, randomly selected phages bound to the monoclonal antibody. Sequence analysis showed that the dominant sequence was SFYDFEMQGFFI. Indirect competitive enzyme-linked immunosorbent assay showed that SFYDFEMQGFFI is a mimotope of the S1 protein that was predicted by PepSurf. The mimotope may provide information for further structural and functional analyses of the S1 protein.
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Shengli Li,Jianan Zhang,Xiaoqun Hou,Yongyi Wang,Tong Li,Zhiming Xu,Feng Chen,Yong Zhou,Weimin Wang,Mingxing Liu 대한신경외과학회 2024 Journal of Korean neurosurgical society Vol.67 No.1
Objective : The spontaneous intracerebral hemorrhage (ICH) remains a significant cause of mortality and morbidity throughout the world. The purpose of this retrospective study is to develop multiple models for predicting ICH outcomes using machine learning (ML). Methods : Between January 2014 and October 2021, we included ICH patients identified by computed tomography or magnetic resonance imaging and treated with surgery. At the 6-month check-up, outcomes were assessed using the modified Rankin Scale. In this study, four ML models, including Support Vector Machine (SVM), Decision Tree C5.0, Artificial Neural Network, Logistic Regression were used to build ICH prediction models. In order to evaluate the reliability and the ML models, we calculated the area under the receiver operating characteristic curve (AUC), specificity, sensitivity, accuracy, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR). Results : We identified 71 patients who had favorable outcomes and 156 who had unfavorable outcomes. The results showed that the SVM model achieved the best comprehensive prediction efficiency. For the SVM model, the AUC, accuracy, specificity, sensitivity, PLR, NLR, and DOR were 0.91, 0.92, 0.92, 0.93, 11.63, 0.076, and 153.03, respectively. For the SVM model, we found the importance value of time to operating room (TOR) was higher significantly than other variables. Conclusion : The analysis of clinical reliability showed that the SVM model achieved the best comprehensive prediction efficiency and the importance value of TOR was higher significantly than other variables.
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Qi Wang,Qianqun Ma,Jianan Zhou,Kongwen Wang 한국증권학회 2023 Asia-Pacific Journal of Financial Studies Vol.52 No.4
This study examines whether differentiated disclosure of key audit matter (KAM) in China indicates a higher financial misstatement risk. Our empirical study demonstrates that financial statements with less boilerplate KAM are more likely to be subsequently restated than those with more boilerplate KAM. This association is only pronounced for smaller auditing firms in stronger legal environments. Additionally, auditors who report differentiated KAM are likely to disclose more risk‐related information. Moreover, clients are more likely to restate financial reports when the KAM relates to managers' subjective estimations.
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Hu, Xi,Sun, Jihong,Li, Fangyuan,Li, Ruiqing,Wu, Jiahe,He, Jie,Wang, Nan,Liu, Jianan,Wang, Shuaifei,Zhou, Fei,Sun, Xiaolian,Kim, Dokyoon,Hyeon, Taeghwan,Ling, Daishun American Chemical Society 2018 Nano letters Vol.18 No.2
<P>Although metallic nanomaterials with high X-ray attenuation coefficients have been widely used as X-ray computed tomography (CT) contrast agents, their intrinsically poor biodegradability requires them to be cleared from the body to avoid any potential toxicity. On the other hand, extremely small-sized nanomaterials with outstanding renal clearance properties are not much effective for tumor targeting because of their too rapid clearance in vivo. To overcome this dilemma, here we report on the hollow bismuth subcarbonate nanotubes (BNTs) assembled from renal-clearable ultrasmall bismuth subcarbonate nanoclusters for tumor-targeted imaging and chemoradiotherapy. The BNTs could be targeted to tumors with high efficiency and exhibit a high CT contrast effect. Moreover, simultaneous radio- and chemotherapy using drug-loaded BNTs could significantly suppress tumor volumes, highlighting their potential application in CT imaging-guided therapy. Importantly, the elongated nanotubes could be disassembled into isolated small nanoclusters in the acidic tumor microenvironment, accelerating the payload release and kidney excretion. Such body clearable CT contrast agent with high imaging performance and multiple therapeutic functions shall have a substantial potential for biomedical applications.</P>
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