외국인 저명학자 초청학술대회 : 중국 종교와 중국의 종교학 ; 중국 종교 문화의 유형

모종감 ( Zhong Jian Mou ),박성숙(역(譯)) 서울대학교 종교문제연구소 2007 종교와 문화 Vol.0 No.13

中國宗敎文化的模式

모종감 ( Zhong Jian Mou ) 서울대학교 종교문제연구소 2007 종교와 문화 Vol.0 No.13

Drug-induced hyperglycaemia and diabetes: pharmacogenomics perspectives

Mou-Ze Liu,Hai-Yan He,Jian-Quan Luo,Fa-Zhong He,Zhang-Ren Chen,Yi-Ping Liu,Da-Xiong Xiang,Hong-Hao Zhou,Wei Zhang 대한약학회 2018 Archives of Pharmacal Research Vol.41 No.7

Drug-induced diabetes is widely reported inclinical conditions, and it is becoming a global issuebecause of its potential to increase the risk of severe cardiovascularcomplications. However, which drug mechanismsexert their diabetogenic effects and why the effectspresent significant inter-individual differences remain largelyunknown. Pharmacogenomics, which is the study ofhow genomic variation influences drug responses, providesan explanation for individual differences in drug-induceddiabetes. We highlight that pharmacogenomics can beinvolved in regulating the expression of genes in signalingpathways related to the pharmacokinetics or pharmacodynamicsof drugs or the pathogenesis of diabetes, contributingto the differences in drug-induced glucoseimpairment. The pharmacogenomics studies of the majordiabetogenic drugs are reviewed, including calcineurininhibitors, antipsychotics, hormones, and antihypertensivedrugs. We intend to elucidate the genetic basis of druginduceddiabetes and pave the way for the precise use ofthese drugs in the clinic.

State Augmented Feedback Controller Design Approach for T-S Fuzzy System with Complex Actuator Saturations

Jian Zhang,Wen-Bo Xie,Mou-Quan Shen,Ling Huang 제어·로봇·시스템학회 2017 International Journal of Control, Automation, and Vol.15 No.5

The control problem of T-S fuzzy system with actuator amplitude, rate and acceleration saturations isaddressed in this paper, where state augmented feedback controller with LMIs (Liner Matrix Inequalities) constraintconditions are proposed. Dynamic decoupling method is applied to fuzzify the input magnitude saturation nonlinearityinto several sub-linear systems with fuzzy rules, thus a new T-S fuzzy system with input rate and accelerationsaturations can be obtained. Then PDC (parallel distributed compensation) and NPDC (non-PDC) controller areboth designed for the new T-S fuzzy system. The first and second order derivatives of input variable are given toobtain an augmented fuzzy system. As the augmented system output variable, the input rate is represented by firstorder derivative of the input term, the rate saturation constraint is described through norm bounded method. Moreover,the polytopic approach is used to replace the second order derivative of the input term, and a state augmentedfeedback NPDC controller is designed, the domain of attraction optimization process is also given. Finally, twopractical examples are presented to show the effectiveness of proposed method.

Overexpression of a Nitrile Hydratase from Klebsiella oxytoca KCTC 1686 in Escherichia coli and Its Biochemical Characterization

Fa-Mou Guo,Jian-ping Wu,Li-Rong Yang,Gang Xu 한국생물공학회 2015 Biotechnology and Bioprocess Engineering Vol.20 No.6

The putative Co-type nitrile hydratase (NHaseK, consisting of α- and β-subunits) genes and the putative activator (17K) gene adjacent to the β subunit region were cloned from Klebsiella oxytoca KCTC 1686. 17K is essential for the functional expression of recombinant NHaseK in Escherichia coli; however, the expression level of 17K was very low when the 17K gene and NHaseK structural genes were expressed as a gene cluster in E. coli BL21(DE3). To improve the 17K expression level and NHaseK activity, the expression cassette was redesigned by placing the 17K gene and NHaseK structural genes under the control of different promoters in the pETDuet-1 expression vector, co-expressing the 17K gene with the gene cluster in a double plasmid or a single plasmid with a double promoter, and introducing an efficient Shine- Dalgarno sequence 5' to the17K gene. The specific activity of NHaseK was improved when 17K was co-expressed with the gene cluster, whereas the production of NHaseK protein decreased. The maximum activity was achieved when an efficient Shine-Dalgarno sequence was introduced 5' to the 17K gene: the expression level of 17K was significantly improved and the expression level of NHaseK did not decrease significantly. The maximum activity was about 63,480 ± 1915.6 U/L broth towards 3-Cyanopyridine. Recombinant NHaseK could hydrolyze a wide range of aliphatic, aromatic, and heterocyclic nitriles, and convert racemic nitriles to the corresponding S-amides, with E values ranging from 9 to 17. The enzyme had a temperature optimum of 35°C and exhibited remarkably stability below 35°C.

정보보안 정책준수에 대한 메타분석: 계획된 행동이론을 중심으로

김종기,MOU JIAN 한국디지털정책학회 2020 디지털융복합연구 Vol.18 No.11

With widespread use of information technologies the importance of information security has been heightened. Security policies which deal with fundamental direction of information security are critical elements of information security management. Numerous studies have been conducted on users’ intention to comply security policies. They were based on various theoretical foundations and the theory of planned behavior(TPB) was the most frequently used. This research employed one of the quantitatively synthesizing meta-analytic techniques called Two-Stage Structural Equation Modeling to investigate factors influencing information security policy compliance behavior based on TPB. Analysis results indicated that all three factors of TPB were significantly influencing the behavioral intention. Moreover, the overall fit indices of structural model exhibited satisfactory level. 정보기술의 발전에 따라 정보보안의 중요성이 갈수록 커지고 있다. 정보보안의 근본적인 방향을 제시하고 조직구성원이 따라야 하는 규정과 지침을 다루는 보안정책은 보안관리의 핵심적인 요소이며, 조직 구성원의 보안정책 준수에 영향을 미치는 다양한 요인에 대한 연구들이 다수 수행되었다. 이들 연구는 다양한 이론적 기반으로 수행되었으며, 여러 문헌연구에 따르면 계획된 행동이론이 가장 빈번하게 사용되었다. 본 연구는 기존의 다양한 연구결과를 정량적으로 종합하는 메타분석 기법 중의 하나인 TSSEM을 적용하여 정보보안 정책준수 행동에 영향을 미치는 요인을 계획된 행동이론을 기반으로 실증분석한 연구들을 대상으로 분석하였다. 분석결과 계획된 행동이론의 행동의도를 설명하는 세 가지 요인인 태도, 주관적 규범 및 인지된 행동통제 모두 유의한 영향을 미쳤으며, 구조방정식 모형의 전반적인 적합도도 만족스럽게 나타났다.

Robust IFNTSM–ESO Control Design for Aircraft Subject to Parameter Uncertainties

Jing Zhang,Jianing Yan,Lingyu Yang,Yuhan Mou 한국항공우주학회 2020 International Journal of Aeronautical and Space Sc Vol.21 No.1

A comprehensive strategy that combines improved fast nonsingular terminal sliding mode (IFNTSM) control and an extended state observer (ESO) is developed to solve the problems of uncertainty in the aeronautical field. First, the IFNTSM control method is proposed to solve the singularity problem and guarantee a faster finite-time convergence speed. Second, an ESO is introduced to estimate the parameter uncertainties, and then a control scheme that combines IFNTSM and ESO is developed to overcome the drawback of large switching gains in a sliding mode controller and alleviate the chattering problem. The stability of the composite system is analyzed via the Lyapunov stability theorem. Finally, the simulation demonstrates that the composite controller accelerates the convergence speed and offers excellent robustness for complex parameter uncertainties.

Netnographic Analysis of Value Practice in the ChatGPT Community

Yuhui Meng,Jian Mou,Jongki Kim,Ying Li 한국경영정보학회 2023 한국경영정보학회 학술대회논문집 Vol.2023 No.11

This paper is a netnographic study based on ChatGPT lovers’ text information in the ChatGPT community. Netnography is the practice of studying a cultural attribute of human beings, or the process of analyzing and exploring the cultural logic or perspective behind a particular group of common interest. The authors selected ChatGPT communities on Facebook and Sina Weibo as the objects of the online field, crawled and summarized the text information in the community by web scrapper technology, and encoded the text content with Nvivo 20 software. Finally, the authors obtained eleven value practice types of ChatGPT lovers in the community, in order to make a preliminary exploration of the theoretical framework of the value practice in the ChatGPT community, and provide some inspiration for subsequent researchers to explore ChatGPT related issues.

Understanding User’s Continuous Use of Financial Technology Products

Wanchao Liu,Huosong Xia,Jian Mou 한국경영정보학회 2021 Asia Pacific Journal of Information Systems Vol.31 No.2

Non-linear FEA of mechanical properties of modular prefabricated steel-concrete composite joints

Wu Cheng Long,Kan Jian Cheng,Liu Ji Ming,Mou Ben 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.4

This paper study the seismic performance of modular prefabricated SRC column to steel beam composite joint (MPCJ) under static loading. Numerical modeling of MPCJs with three different beam-end connections was carried out in ABAQUS. Results of the numerical calculation were compared with existing quasi-static test results to verify the feasibility of the numerical model. The model was then used to analyze changes in the moment-rotation relation, failure mode, ductility, stiffness, and bolt stress in the joint between the column and joint module. Besides, stress distributions in the joints were analyzed along different stress paths. Under monotonic loading, the mechanical performance of the MPCJ is significantly affected by the beam end connection mode. Failure of the MPCJ mainly occurs at the beam end connection, thus, the aim of keeping the plastic hinge away from the joint core and preventing shear failure is achieved. Furthermore, the maximum story drift ratio is 3.9–5 times greater than the recommended limit, which indicates good ductility and deformation performance. The MPCJ of the three-beam end connection methods is all semi-rigid connections. The beam end structure will have a large influence on the bolt tension and stress distribution. According to the test research results, a nonlinear model with three parameters including joint cover plate cantilever section length, flange connecting plate thickness and flange connecting plate weld length was established. The theoretical calculation results was consistent with the results of the numerical simulation. MPCJs can be designed based on the proposed theoretical calculation formula.