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      • On Resolving Key Escrow Problem in HIBE and HIBS

        Jian-Wu Zheng,Jing Zhao,Xin-Ping Guan 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.6

        In traditional hierarchical identity based cryptosystems (HIBC), non-leaf entities as level PKGs are usually capable of deriving private keys for their descendants with use of their private keys, non-leaf entities can therefore act (decrypt or sign) on the behalf of their arbitrary descendants. This is called key escrow problem of HIBC. In order to resolve key escrow problem, a new technique – Identifier Discrimination is proposed in this paper for composing private keys for entities in hierarchy. With the technique, an identity selective secure HIBE scheme is constructed under Decisional Bilinear Diffie- Helleman (DBDH) assumption in standard security model, in which any identity is incapable of deriving private keys for any of its descendants with use of its private key, and the privilege of generating private keys for each individual descendant is delegated by the root PKG through authorization, that we call Authorization Delegation. Moreover, a new hierarchical identity based signature (HIBS) scheme is constructed from our HIBE construction, by applying Naor transformation of an identity-based signature (IBS) out of an IBE. Because of the inability of deriving its descendants’ private keys with use its private key, an entity therefore cannot sign messages on behalf of any of its descendants, thus guaranteeing that authenticity and non-repudiation properties are achieved in our HIBS system.

      • KCI등재

        Ethosomes, Binary Ethosomes and Transfersomes of Terbinafine Hydrochloride: A Comparative Study

        Jian-Ping Zhang,Xin-An Wu,Yu-Hui Wei,Yan Zhou,Yu-Qing Li 대한약학회 2012 Archives of Pharmacal Research Vol.35 No.1

        The aim of this study was to compare the skin permeation of ethosomes, binary ethosomes and transfersomes of Terbinafine Hydrochloride (TH) under non-occlusive conditions. These lipid vesicles were prepared and characterized for shape, size, zeta-potential and entrapment efficiency. Franz diffusion cells and confocal laser scanning microscopy (CLSM) were used for the percutaneous absorption studies. The quantity of drug in the skin from ethosomes, binary ethosomes (the weight ratio of ethanol to propylene glycol 7:3, ethanol-PG = 7:3, w/w), and transfersomes was 1.26, 1.51 (p <0.05), 1.56 (p <0.01) times higher than that of TH from traditional liposomes (control). The skin deposition of the applied dose (DD%) of TH from ethosomes, binary ethosomes, and transfersomes was 3.34 (p < 0.05), 9.88 (p < 0.01), 2.52 times higher than that of TH from control. The results of CLSM experiments showed that penetration depth and fluorescence intensity of Rhodamine B from binary ethosomes was much greater than that from ethosomes and transfersomes. These results indicated the binary ethosomes (ethanol-PG = 7:3, w/w) most effectively permitted drug penetration through skin; transfersomes made drug easiest to accumulate in the skin. Ethosomes improved drug delivery with greater improvement in skin permeation than improvement in skin deposition.

      • KCI등재

        Stem Cell-Derived Exosomes: A New Method for Reversing Skin Aging

        Wu Jinyan,Wu Sai-Nan,Zhang Li-Ping,Zhao Xiansheng,Li Yue,Yang Quyang,Yuan Ruoyue,Liu Jian-Lan,Mao Hong-Ju,Zhu Ningwen 한국조직공학과 재생의학회 2022 조직공학과 재생의학 Vol.19 No.5

        Senescence is an inevitable natural life process that involves structural and functional degeneration of tissues and organs. Recently, the process of skin aging has attracted much attention. Determining a means to delay or even reverse skin aging has become a research hotspot in medical cosmetology and anti-aging. Dysfunction in the epidermis and fibroblasts and changes in the composition and content of the extracellular matrix are common pathophysiological manifestations of skin aging. Reactive oxygen species and matrix metalloproteinases play essential roles in this process. Stem cells are pluripotent cells that possess self-replication abilities and can differentiate into multiple functional cells under certain conditions. These cells also possess a strong ability to facilitate tissue repair and regeneration. Stem cell transplantation has the potential for application in anti-aging therapy. Increasing studies have demonstrated that stem cells perform functions through paracrine processes, particularly those involving exosomes. Exosomes are nano-vesicular substances secreted by stem cells that participate in cell-to-cell communication by transporting their contents into target cells. In this chapter, the biological characteristics of exosomes were reviewed, including their effects on extracellular matrix formation, epidermal cell function, fibroblast function and antioxidation. Exosomes derived from stem cells may provide a new means to reverse skin aging.

      • KCI등재

        Isolation of a Natural Antioxidant, Dehydrozingerone from Zingiber officinale and Synthesis of Its Analogues for Recognition of Effective Antioxidant and Antityrosinase Agents

        Ping-Chung Kuo,Amooru G. Damu,Ching-Yuh Cherng,Jye-Fu Jeng,Che-Ming Teng,E-Jian Lee,Tian-Shung Wu 대한약학회 2005 Archives of Pharmacal Research Vol.28 No.5

        In the present study, the antioxidative and inhibitory activity of Zingiber officinale Rosc. rhizomes- derived materials (on mushroom tyrosinase) were evaluated. The bioactive components of Z. officinale rhizomes were characterized by spectroscopic analysis as zingerone and dehydrozingerone, which exhibited potent antioxidant and tyrosinase inhibition activities. A series of substituted dehydrozingerones [(E)-4-phenyl-3-buten-2-ones] were prepared in admirable yields by the reaction of appropriate benzaldehydes with acetone and the products were evaluated in terms of variation in the dehydrozingerone structure. The synthetic analogues were examined for their antioxidant and antityrosinase activities to probe the most potent analogue. Compound 26 inhibited Fe2+-induced lipid peroxidation in rat brain homogenate with an IC50 = 6.3±0.4 µM. In the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical quencher assay, compounds 2, 7, 17, 26, 28, and 29 showed radical scavenging activity equal to or higher than those of the standard antioxidants, like α-tocopherol and ascorbic acid. Compound 27 displayed superior inhibition of tyrosinase activity relative to other examined analogues. Compounds 2, 17, and 26 exhibited non-competitive inhibition against oxidation of 3,4- dihydroxyphenylalanine (L-DOPA). From the present study, it was observed that both number and position of hydroxyl groups on aromatic ring and a double bond between C-3 and C-4 played a critical role in exerting the antioxidant and antityrosinase activity.

      • KCI등재

        Analysis of Shear Connector of Steel–Concrete Composite Box-Girder Bridge Considering Interfacial Bonding and Friction

        Jian-Ping Lin,ZhiBo Wu,Ying Yin,Fan Feng 한국강구조학회 2020 International Journal of Steel Structures Vol.20 No.2

        Steel–concrete composite bridges consist of steel and concrete parts which are connected by shear connector such as the widely-used headed stud. Through the chemistry bonding, interface friction and mechanical action the two different materials parts are combined as a composite structure system. Because of the structural mechanism, longitudinal and lateral relative slip and normal separation between the concrete deck and steel girder flange will inevitably exist during the loading process. Further, the complex interface mechanical behavior causes difficulties with nonlinear numerical analysis. Multiple broken lines mode cohesive zone model considering bonding and friction is used in this paper to describe the tangent slip and normal crack of the interface. A zero thickness cohesive element was implemented via the user-defined element subroutine UEL in ABAQUS. Using this method, numerical simulation analysis of a two span composite continuous box-girder was carried out. Results showed load–displacement curves of the structure, relative displacement between the steel girder and the concrete slab interface, interface stress distribution, and internal force of shear studs. Discontinuous deformation numerical simulation has been realized, and effectiveness of the proposed method and accuracy of the program were verified. Although shear stress was assumed to be transmitted by shear connector in the design stage, interface bonding and friction resistance can affect the force state of the shear connector. Results of this study can be used for detailed analysis and evaluation of the composite box-girder bridge without the need to rely on the constitutive laws of shear connectors obtained from push-out tests.

      • Application of RBF Neural Network in Fault Diagnosis of FOG SINS

        Wu Lei,Sun Rong-Ping,Cheng Jian-Hua 제어로봇시스템학회 2008 제어로봇시스템학회 국제학술대회 논문집 Vol.2008 No.10

        Taking FOG SINS (fiber-optic gyroscope strapdown inertial system) as an object, a new fault diagnostic scheme based on RBF(radial basis function) neural network is proposed. Being capable of training and simulating data off-line, neural networks provide a solution to overcome some drawbacks of the quantitative fault diagnosis. The fault tree of FOG SINS is analyzed, which is the basis of the study of neural network fault diagnosis technology. The structure and inferential mechanism of RBF network used for elementary fault diagnosis are discussed in detail. Training simulation results of the neural network are given and an improved effect with real data is obtained, which show the feasibility of the proposed scheme.

      • KCI등재

        Face Stability Analysis of Slurry Shield Tunnels in Rock–Soil Interface Mixed Ground

        Ping Lu,Da-Jun Yuan,Jian Chen,Dalong Jin,Jun Wu,Weiping Luo 대한토목학회 2021 KSCE Journal of Civil Engineering Vol.25 No.6

        When shield tunneling in rock-soil interface (RSI) mixed ground, maintaining the stability of the tunnel face is very challenging. This study aims at the investigation of the face stability of slurry shield tunnels in RSI mixed ground. A new apparatus was developed to simulate pressurized slurry supporting the tunnel face in centrifuge tests. The progressive failure of the tunnel face was triggered with slow decrease of slurry pressure. With two equivalent model tunnels of circular shape and semicircular shape, the variations of soil (water) pressure and the displacement field in front of the tunnel can be obtained simultaneously. The face failure was found to be a local collapse in the upper soil layer. The limit support pressure was picked out at the sudden change of the measured soil or water pressures. Then the classical wedge-prism model was introduced and modified to calculate the limit support pressure for slurry shield tunnels in RSI mixed ground considering the partial collapse. Numerical analysis was applied to verify the theoretical analysis and sensitivity analysis was performed to estimate the influence of different parameters on the theoretical solutions.

      • KCI등재
      • KCI등재후보

        Analysis of Volatile Compounds of Jasmine Scented Tea during the Orthodox Manufacturing Process Using HS-SPME/GC-MS

        Jian Lu,De-Jun Fu,Dong-Fen Wu,Yu Liu,Yao-Ping Luo 한국차학회 2015 한국차학회지 Vol.- No.S

        Volatile components of jasmine-scented tea during the orthodox manufacturing process were extracted using Headspace solid-phase microextraction (HS-SPME) and the major flavor compounds were identified by Gas chromatography-mass spectrometry/Retention indices (GC-MS/RI). The major volatile compounds extracted by SDE could also be obtained by HS-SPME, which appears more suitable for extraction of aromatic compounds, for its advantages of simplicity and convenience. The GC-MS chromatograms of tea samples showed that the aromatic constituents of jasmine tea had been identified in composition after 1st scenting, which contained 6 apparently high peaks representing linalool, benzyl acetate, α-farnesene, (Z)-3-hexenyl benzoate, methyl anthranilate, and indole. According to the change of peak area of major volatile compounds, (Z)-3-hexenyl acetate and (Z)-3-hexenyl butyrate with green grass aroma reduced by 71.13% and 63.10% respectively in jasmine tea product, while 7 compounds with favorable flowery fruity aroma-benzyl acetate, (Z)-3-hexenyl benzoate, linalool, benzyl alcohol, α-farnesene, methyl anthranilate and indole- increased by 17.84%, 28.33 times, 32.49%, 1.70 times, 6.67 times, 11.84 times and 21.48 times respectively, comparing to the base tea. Besides, nerolidol (fruity-flowery) and germacrene D (woody), not detected in the base tea also gradually increased. The quality grade of jasmine tea was potentially correlated to the ratio of peak area of the 9 favorable compounds to that of the 2 grass compounds. After 1st scenting, the peak areas of compounds from jasmine flower increased by 1.81×105-18.24×105, and decreased by 36.14%-69.95% after the 1st drying. The peak areas of some components detected in both the base tea and jasmine flowers, like (Z)-3-hexenyl acetate and methyl salicylate, increased by 9.05%-57.60% of those of the base tea after 1st scenting, and lost more than 100% after the 1st drying, while the increased peak areas of some other components both detected, like α-farnesene and indole, were more than peak areas of the base tea, with 30%- 95% loss after the 1st drying. The content change tendency of volatiles during 2nd scenting and the 2nd drying were consistent with those during 1st scenting and the 1st drying. After raising fragrance, the contents of some low boiling point volatiles and compounds not detected in the base tea increased.

      • Differentiating Technique: Constructing Efficient HIBE with Constant Size Ciphertext and Authorized Delegation

        Jian-Wu Zheng,Jing Zhao,Xin-Ping Guan 보안공학연구지원센터 2016 International Journal of Security and Its Applicat Vol.10 No.8

        As Hierarchical Identity Based Encryption (HIBE) system usually maps the true institutional structure of an organization or entity relationship between objects in real world, It is important that computation & communication complexity of private key, ciphertext, cryptographic computations and so on related to an entity in the hierarchy is independent to the hierarchy depth of the entity. Moreover, key escrow problem that any non-leaf entity in a hierarchical identity based cryptosystem can derive private keys for its descendants with use of its private key should be resolved, in order to prevent any entity from behaving on behalf of its descendants. In this paper, a new technique is introduced for composing a private key for each individual entity in HIBE system by differentiating between non-local identifiers and local identifiers of the identity of the entity. That we call Identifier Discrimination. With the technique, A selective identity secure HIBE system is constructed under Decisional Bilinear Diffie-Hellman (DBDH) assumption without using random oracles, where the private key and the ciphertext consist of constant number of group elements, and decryption requires only three bilinear map computations, regardless of the identity hierarchy depth. Moreover, in contrast to previous HIBE constructions, where private key for an entity can be derived by its ancestors with direct use of their private keys, key escrow problem inherent in identity based cryptosystems is resolved in our HIBE construction. Privilege of deriving private keys for an entity can be delegated to any of its ancestors through authorization by distributing specifically crafted values to the ancestor in our HIBE system, that we call Authorized Delegation.

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