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Jiachao Chen,Songsheng Zheng,Xing Yang,Ying Lv,Yang Li,Chao Chen 대한금속·재료학회 2020 ELECTRONIC MATERIALS LETTERS Vol.16 No.6
It has great significance to find a path on generating multicolor with one n-UV chip coated with single phosphor. Herein, Eu doped Na2Al2B2O7 (NAB) phosphor is synthesized by solid state reaction in air atmosphere. Both 4f65d1 → 4f7 transitions of Eu2+ (445 nm) and f–f transitions as 5D0 → 7FJ (J = 0, 1, and 2) of Eu3+ (570–650 nm) have been observed. When increasing Eu doping concentration, both the luminescence intensity and lifetime of Eu3+ are increased and no obvious concentration quenching is observed, while the emission strength of Eu2+ does not change monotonically but with two remarkable peak values. The optimum doping concentration of Eu is 16%. Furthermore, Eu3+ is determined to be from Eu(BO3) matrix itself, and Eu2+ testified by ESR and XPS is created by self-reduction of Eu3+ to Eu2+ in NAB due to charge compensation. When x ≥ 0.16, the Eu3+ ion would rather bond with BO3 triangles in Eu(BO3) than stay as Eu2+ in AlO4 tetrahedral in NAB. Furthermore, the as prepared sample shows an excellent thermal stability and the PL quantum efficiencies of NAB: 0.16Eu sample excited by 341 nm and 393 nm are 11.99% and 9.39%, respectively. Additionally, the calculated CIE chromaticity coordinates signify that a couple of colors can be generated by adjusting the excitation wavelength owing to the strength changes between blue and red emissions. Therefore, this novel bicolor phosphor can serve as a potential candidate for w-LEDs applications.
( Qianqian Pang ),( Yuming Wang ),( Mingyuan Xu ),( Jiachao Xu ),( Shengquan Xu ),( Yichen Shen ),( Jinghong Xu ),( Rui Lei ) 생화학분자생물학회(구 한국생화학분자생물학회) 2019 BMB Reports Vol.52 No.3
Keloids are the most common pathological form of trauma healing, with features that seriously affect appearance and body function, are difficult to treat and have a high recurrence rate. Emerging evidence suggests that miRNAs are involved in a variety of pathological processes and play an important role in the process of fibrosis. In this study, we investigated the function and regulatory network of miR-152-5p in keloids. The miRNA miR-152-5p is frequently downregulated in keloid tissue and primary cells compared to normal skin tissue and fibroblasts. In addition, the downregulation of miR-152-5p is significantly associated with the proliferation, migration and apoptosis of keloid cells. Overexpression of miR-152-5p significantly inhibits the progression of fibrosis in keloids. Smad3 is a direct target of miR-152-5p, and knockdown of Smad3 also inhibits fibrosis progression, consistent with the overexpression of miR-152-5p. The interaction between miR-152-5p and Smad3 occurs through the Erk1/2 and Akt pathways and regulates collagen3 production. In summary, our study demonstrates that miR-152-5p/Smad3 regulatory pathways involved in fibrotic progression may be a potential therapeutic target of keloids. [BMB Reports 2019; 52(3): 202-207]
Jinjia He,Yi Chen,Luyao Dai,Jiachao Yao,Yu Mei,Dzmitry Hrynsphan,Savitskaya Tatsiana,Jun Chen 한국생물공학회 2020 Biotechnology and Bioprocess Engineering Vol.25 No.4
Acrylic acid is used in various industrial applications but inflicts harm to human health and causes environmental pollution. A new bacterium, identified as Rhodococcus ruber JJ-3, was isolated, which can degrade high concentrations of acrylic acid rapidly and completely. Experimental results showed that the strain can achieve complete degradation of 1000 mg·L−1 acrylic acid in 11 h under the following conditions: pH 7, temperature 35°C, and inoculation quantity 15%. A high concentration of acrylic acid (2000 mg·L−1) can be completely removed in 28 h. According to the Monod model, the maximum specific degradation rate (vmax) and half saturation rate constant (KS) of the strain were 0.85 h−1 and 101.83 mg·L−1, respectively. The results of carbon balance revealed that 54.6% carbon was assimilated by R. ruber JJ-3 as biomass, and 43.0% carbon was mineralized into CO2. Furthermore, glycerol and lactic acid were measured as intermediates, and the possible degradation pathway was proposed during the biodegradation of acrylic acid. These results suggested that R. ruber JJ-3 completely degrades acrylic acid and might have a potential environmental implication in the purification of acrylic acid-contaminated environments.
A review of preparation techniques of porous ceramic membranes
Peng Wu,Yuezhong Xu,Zhenxing Huang,Jiachao Zhang 한양대학교 세라믹연구소 2015 Journal of Ceramic Processing Research Vol.16 No.1
Porous ceramic membranes with their various advantages, such as better thermal, chemical and mechanical resistance, controllable micro-structure and little pollution to our environment, have been attracting much attention in the scientific community recently. With the development of technology, lowering the cost of ceramic membranes and prepare membranes with high permeability, high selectivity is becoming more important. The advances in the past ten years in techniques are reviewed. Finally, prospect of ceramic membranes was predicted.
Current progress in remediation of chlorinated volatile organic compounds: A review
Chunhao Dai,Yaoyu Zhou,Hui Peng,Shaojian Huang,Pufeng Qin,Jiachao Zhang,Yuan Yang,Lin Luo,Xiaoshan Zhang 한국공업화학회 2018 Journal of Industrial and Engineering Chemistry Vol.62 No.-
Chlorinated volatile organic compounds (Cl-VOCs) contamination has been recognized as one of the major problem in worldwide due to natural and anthropogenic activities. Recently, several treatment technologies (e.g., adsorption for broader concentration Cl-VOCs, catalytic combustion for high concentration (>500 ppm), advanced oxidation, electrochemical method, metal method and photocatalytic method for low concentration (<500 ppm)) have been applied for Cl-VOCs elimination. In this review, an extensive list of every method from literatures is compiled, and their capacities under various conditions are presented. However, there is still need to find out the practical technologies on commercial scale, leading to improvement of environmental pollution control.
LeiWang,Hye-Won Yang,Ginnae Ahn,Xiaoting Fu,Jiachao Xu,Xin Gao,You-Jin Jeon 제주대학교 해양과학연구소 2021 해양과환경연구소 연구논문집 Vol.45 No.-
In the present study, the in vitro and in vivo anti-inflammatory effects of the sulfated polysaccharides isolated from Sargassum fulvellum (SFPS) were evaluated in lipopolysaccharide (LPS)- stimulated RAW 264.7 macrophages and zebrafish. The results indicated that SFPS improved the viability of LPS-stimulated RAW 264.7 macrophages from 80.02 to 86.80, 90.09, and 94.62% at the concentration of 25, 50, and 100 μg/mL, respectively. Also, SFPS remarkably and concentrationdependently decreased the production levels of inflammatory molecules including nitric oxide (NO), tumor necrosis factor-alpha, prostaglandin E2, interleukin-1 beta, and interleukin-6 in LPStreated RAW 264.7 macrophages. In addition, SFPS significantly inhibited the expression levels of cyclooxygenase-2 and inducible nitric oxide synthase in LPS-treated RAW 264.7 macrophages. Furthermore, the in vivo test results indicated that SFPS improved the survival rate of LPS-treated zebrafish from 53.33 to 56.67, 60.00, and 70.00% at the concentration of 25, 50, and 100 μg/mL, respectively. In addition, SFPS effectively reduced cell death, reactive oxygen species, and NO levels in LPS-stimulated zebrafish. Taken together, these results suggested that SFPS possesses strong in vitro and in vivo anti-inflammatory activities, and could be used as an ingredient to develop anti-inflammatory agents in the functional food and pharmaceutical industries.
LeiWang,Hyun-Soo Kim,Jun-Geon Je,Xiaoting Fu,Caoxing Huang,Ginnae Ahn,Jae-Young Oh,K. K. Asanka Sanjeewa,Jiachao Xu,Xin Gao,In-Kyu Yeo,You-Jin Jeon 제주대학교 해양과학연구소 2021 해양과환경연구소 연구논문집 Vol.45 No.-
Skin is the largest organ of humans. Overexposure to ultraviolet (UV) is the primary environmental factor that causes skin damage. The compound, (-)-loliode, isolated from the brown seaweed Sargassum horneri, showed strong antioxidant and anti-inflammatory activities in in vitro and in vivo models. To further explore the potential of (-)-loliode in cosmetics, in the present study, we investigated the photoprotective effect of (-)-loliode in vitro in skin cells and in vivo in zebrafish. The results indicated that (-)-loliode significantly reduced intracellular reactive oxygen species (ROS) level, improved cell viability, and suppressed apoptosis of UVB-irradiated human keratinocytes. In addition, (-)-loliode remarkably attenuated oxidative damage, improved collagen synthesis, and inhibited matrix metalloproteinases expression in UVB-irradiated human dermal fibroblasts. Furthermore, the in vivo test demonstrated that (-)-loliode effectively and dose-dependently suppressed UVB-induced zebrafish damage displayed in decreasing the levels of ROS, nitric oxide, lipid peroxidation, and cell death in UVB-irradiated zebrafish. These results indicate that (-)-loliode possesses strong photoprotective activities and suggest (-)-loliode may an ideal ingredient in the pharmaceutical and cosmeceutical industries.