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송준영,이규석,최윤애,노용지 啓明大學校 醫科大學 1990 계명의대학술지 Vol.9 No.4
Reactions are acute or subacute hypersensitivity states that complicated the existing active and, more often, the treated infection. A modern description of reactions in Hansen's disease will include 3 types such as Type 1 reaction, erythema nodosum leprosum, and Lucio's phenomenon. Type 1 reaction occurs in patients suffering from borderline leprosy during the first six months of treatment. Characteristic symptoms are nerve pain concomittently with muscle paralysis, rapid swelling & erythema of some or all of the skin lesions and edema of face, hands & feet. It is generally considered that this type of reaction is a delayed hypersesitivity phenomenon in which antigen from breaking down bacilli reacts with T lymphocytes. Our case was sixty five year old woman who had multiple erythematous, swollen lesions on the both hands, feet and face, and suffered from paresthesia, dyshydrosis and mild tenderness on that sites 1 year ago. The symptoms were more aggrevated 20 days ago. General symptoms were accompanied such as fever, malaise, fatigue, loss of appetite. Family and past history was non contributory. And we tried many tests, skin smear and skin biopsy and then concluded final diagnosis was borderline tuberculoid leprosy with type 1 reaction. We had treated this patient with 20-40㎎ of prednisolone, 100㎎ of dapsone, 200㎎ of clofazimine and 600㎎ of rifampicin daily for a week, and then, had transfered to special leprosy clinic in the mild improved state. Now we present a case of borderline tuberculoid leprosy with type 1 reaction with references.
Yae Eun Kwon,Un Seop Shin,Ji Woo Park,Su Jung Song,Sang In Lee,Sang Yong Kim,Mi Jin Jeong 한국화훼학회 2020 화훼연구 Vol.28 No.3
본 연구는 기존에 절화용으로 개발되지 않았던 벼룩이울타리를 절화로써의 가치와 가능성을 증명함으로써 새로운 관상식물로 개발하기 위해 수행되었다. 실험은 온도, 보존용액, 절화 수명연장제에 따른 절화 벼룩이울타리의 영향을 구명하고자 절화수명, 수분흡수량, 생체중을 조사하였다. 수확 후 절화는 4, 15, 20, 25°C의 온도 조건에 따른 영향력과 1, 3% sucrose 와 8-hydroxqui-noline sulfate(8-HQS) 10, 50, 100mg・L-1 혼 용보존용액, 절화수명연장제 Chrysal와 Floarlife을 처리하였다. 저장 온도에 따른 실험 결과, 절화 벼룩이울타리는 저온 (4°C)에서의 저장에서의 절화수명이 대조구(7.8일)보다 29일 연장되었다. 온도가 낮을수록 절화의 품질과 수명에 가장 효과적이었다. sucrose와 8-HQS의 효과 확인을 위해 가장 낮은 농도의 당과 살균제를 혼용한 1% sucrose+8-HQS 10mg・L-1를 제외한 나머지 3개의 보존용액 대조구(6.5±0.5일)에 비하여 절화수명이 약 2주 연장되었다. 또한, 절화수명연장제 Chrysal 과 Floarlife는 sucrose와 8-HQS의 혼용보존용액과 절화수명에 유의적인 차이는 없었다. 한편, 모든 실험 조건에서 수분흡수량과 생체중의 급격한 감소는 절화수명의 단축됨과 연관이 있다는 것을 확인하였다. This study investigated the optimum temperature and holding solutions for the storage of cut flowers of Arenaria juncea M. Bieb. to facilitate their introduction as a new ornamental plant. We examined the effects of different holding solutions on the water uptake, vase life, and fresh weight of five branches of A. juncea. After harvest, cut branches were stored at 4, 15, 20, and 25°C. To study the effect of the holding solutions, the cut branches were treated with a combination of sucrose (1% and 3%), 8-hydroxyqunoline sulfate (8-HQS: 10, 50, and 100 mg·L-1), and commercial preservative solutions Chrysal and Floralife. At a storage temperature of 4°C, the vase life was 29 days, which was significantly longer compared to room temperature, where the vase life was 7.8 days. Thus, a lower temperature was more effective at extending the vase life. A combination of 1% sucrose and 100 mg·L-1 8-HQS prolonged the vase life by approximately two weeks compared to the control. The effect of both Chrysal and Floralife was similar to the effect of the holding solutions composed of sucrose and 8-HQS. Moreover, rapid reduction of water uptake and fresh weight resulted in a shorter vase life.
Kim, Ji Young,Kim, Oh Yoen,Hyun, Yae Jung,Koo, Sun Mo,Song, Sang Hoon,Jang, Yangsoo,Lee, Jong Ho The Korean Nutrition Society 2004 Nutritional Sciences Vol.7 No.4
In this study, we examined the effects of dietary 1,3-diacylglycerol (DG) compared to conventional triacylglycerol (TG) oil on the postprandial response of total and chylomicron TG, glucose, insulin, and free fatty acid (FFA). This study was conducted using a cross-over design. Ninety subjects participated in the high-fat meal tolerance test where they were randomly assigned to consume two experimental sandwiches containing mayonnaise with TG or DG oil with a seven-day interval. Blood samples were collected before ingestion and at 2, 3, 4 and 6 hr time point after ingestion and analyzed for total and chylomicron TG, glucose, insulin, FFA and phospholipid fatty acid composition. Both TG and DG ingestion had similar effects on postprandial TG response, but a different response from chylomicron TG. Compared with the TG group, TG levels were significantly lower only at 6 hr time point in the DG group. On the other hand, chylomicron TG rose steeply at 2 hr time point and decreased faster in this group. Also, the adjusted value to fasting levels was the same as the unadjusted level. Fasting levels and net differences in insulin were significantly lower at 3 hr time point where chylomicron TG levels were significantly lower in the DG group. But those of glucose and FFA in the TG and DG groups did not differ significantly. Fasting and postprandial levels of fatty acid composition in serum phospholipids in the two groups did not differ significantly. In conclusion, this study indicated that one could reduce the magnitude of postprandial lipemia without influencing glucose metabolism by consumning DG oil as a substitute for TG oil. Based on the correlation of coronary artery disease and postprandial lipemia, dietary DG ingestion might have a beneficial effect in treating such a disease. Further studies are required to clarify the long-tenn effects of dietary DG on blood lipid levels in humans.
송채원 ( Chae-won Song ),오승아 ( Seung-a Oh ),정다예 ( Da-yae Jeong ),임유리 ( Yuri Lim ),노은지 ( Eun-ji Rho ),이규영 ( Gyu-young Lee ) 한국정보처리학회 2021 한국정보처리학회 학술대회논문집 Vol.28 No.2
본 논문에서는 머신러닝 시스템에 심각한 오류를 발생시킬 수 있는 적대적 샘플을 제작하고, 이를 이용한 적대적 공격을 효과적으로 예방하고 방어할 수 있는 Adversarial Training 기반의 AI 백신을 개발하였으며, 본 논문이 제안하는 AI 백신이 적대적 샘플을 올바르게 인식하고 AI 공격 성공율을 현저하게 낮추는 등 강인성을 확보한 것을 실험을 통해 입증하였다. 아울러 스마트폰을 통해 수행결과를 확인할 수 있는 어플리케이션을 구현하여, 교육 및 시연 등을 통해 적대적 AI 공격에 대한 심각성을 인식하고 해당 방어과정을 명확히 이해할 수 있도록 하였다.
Chung, Hye Kyung,Chae, Jey Sook,Hyun, Yae Jung,Paik, Jean Kyung,Kim, Ji Young,Jang, Yangsoo,Kwon, Hyuck Moon,Song, Young Duk,Lee, Hyun Chul,Lee, Jong Ho American Diabetes Association 2009 Diabetes care Vol.32 No.4
<P><B>OBJECTIVE</B></P><P>The aim of this study was to determine the effect of common adiponectin gene polymorphisms on dietary intervention-mediated changes in adiponectin levels and homeostasis model assessment of insulin resistance (HOMA-IR) indexes.</P><P><B>RESEARCH DESIGN AND METHODS</B></P><P>A total of 363 subjects with impaired fasting glucose (IFG) or newly diagnosed type 2 diabetes followed a dietary intervention (replacement of cooked refined rice with whole grains and an increase in vegetable intake) and regular walking for 12 weeks without any medication. Adiponectin gene single nucleotide polymorphisms (SNPs) (45, 276, and −11377) were examined in these subjects.</P><P><B>RESULTS</B></P><P>After this dietary intervention, fasting glucose levels decreased in all three SNP 45T>G genotype groups. Subjects with the SNP 45TT genotype showed increased adiponectin levels and decreased HOMA-IR indexes. Haplotype analysis revealed that homozygous carriers of the TG haplotype (45TT and 276GG) and heterozygous carriers of the TG haplotype (TG/X) showed a reduction in the HOMA-IR index after adjustment for baseline levels. Significant differences were observed in changes in HOMA-IR indexes and adiponectin concentrations according to the 45-276 TG haplotype in overweight-obese, but not in normal-weight subjects: the greatest decrease in HOMA-IR indexes and the greatest increase in adiponectin levels were shown in overweight-obese subjects with the TG/TG haplotype.</P><P><B>CONCLUSIONS</B></P><P><I>ADIPOQ</I> genetic variants can affect circulating adiponectin levels and insulin resistance indexes in subjects with IFG or newly diagnosed type 2 diabetes in response to dietary intervention.</P>