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하수 2차 처리수 재이용을 위한 저압 및 중압 고도산화시스템의 성능평가
안규홍,안석,맹승규,김기팔,홍준석,정민우,권지향,Ahmed, Zubair 대한상하수도학회 2003 상하수도학회지 Vol.17 No.4
In the present study, the feasibility of UV/H₂O₂ systems was investigated using low and medium-pres sure lamps on biologically treated wastewater effluents for secondary effluent reclamation. Two types of UV lamps were used as the light sources (a 33W lowpressure mercury lamp and a 350-W mediumpressure mercury lamp). The results from these UV systems showed that the removal of organic compounds could be achieved in the contact time of longer than 30min (i.e., low UV doses). Efficiencies of color removal and disinfection were far better than those of organic matters measured as TOC, DOC and TCOD_(cr). In the low pressure lamp UV system, it has been found that DOC and color removals were 60.9 and 86.2% with 50㎎/L of H₂O₂ and contact times of 30 minute, respectively. Whereas, with the mediumpressure lamp UV system, TOC, DOC and color removal were 27.1, 5.6 and 95% with 14.3㎎/L of H₂O₂ and 14 minute of contact times, respectively. Both systems could be applied for the reclamation of secondary effluent treated with biological treatment processes.
피부 지질 조성 모사 Ceramide 액정 에멀젼의 피부 장벽 강화 효과 확인에 관한 연구
한지혜 ( Ji Hye Han ),이주연 ( Ju Yeon Lee ),이관형 ( Kwan Hyoung Lee ),김희선 ( Hee Sun Kim ),박창열 ( Chang Yeol Park ),맹지혜 ( Ji Hye Maeng ),소지민 ( Ji Min So ),남개원 ( Gae Won Nam ),김상철 ( Sang Chul Kim ) 대한화장품학회 2021 대한화장품학회지 Vol.47 No.1
본 연구에서는 ceramide, 당지질, cholesterol, 지방산을 이용하여 피부 지질 조성과 유사한 조성비를 갖는 액정 에멀젼을 제조하고 편광 현미경을 통해 제형 내 액정 입자를 확인하고, cryso-SEM을 이용하여 다층구조가 형성되었음을 확인하였다. 상기 제조된 샘플은 1 개월간 상온에 보관하여 액정구조가 지속적으로 유지되는 것을 현미경 관찰을 통해 확인하였다. 또한, 이렇게 제조된 액정 에멀젼을 포함하는 크림 조성물을 제조하고, 3 차원 인공피부를 활용한 ceramide 피부 투과 효율을 확인하였다. 해당 크림 조성물을 활용하여 임상시험을 진행하고 일반 에멀젼 대비 피험자의 피부 수분 보유량(skin hydration), 경피 수분 손실량(TEWL)을 측정함으로써 피부 장벽 개선에 대한 임상 실험 결과를 확인하였다. In this study, a liquid crystal emulsion with a composition ratio similar to the skin lipid composition was manufactured using ceramide, glycolipids, cholesterol, and fatty acids, and a polarized microscope was used to identify liquid crystal particles in the formulation, and a cryso-SEM was used to confirm the formation of a multilayer structure. The above samples were stored at room temperature for one month and the liquid crystal structure was continuously maintained through microscopic observation. In addition, a cream composition containing liquid crystal emulsion was manufactured, and the efficiency of ceramide skin penetration was confirmed using three-dimensional artificial skin. Clinical trials were conducted using the cream composition and the results of clinical trials on skin barrier improvement were confirmed by measuring skin moisture retention (skin hydration) and transepidermal water loss (TEWL) of subjects compared to general emulsion.
시스템 패키징을 위한 Thin-Film 기반 수동소자 구현
맹지민(Ji-Min Maeng),유찬세(Chan-Sei Yoo),송생섭(Sang-Sub Song),이희석(Hee-Seok Lee),서광석(Kwang-Seok Seo) 대한전자공학회 2007 대한전자공학회 학술대회 Vol.2007 No.7
Embedded passive devices were developed with thin-film multichip module-deposited (MCM-D) technology. The features of integrated passives are NiCr resistors with 20Ω/square, compact spiral inductors with inductance ranging from 3 to 10 nH, and 900A SiNx MIM capacitors with scalable capacitance as well as high breakdown voltage.
Alternative skin irritation test using the MCTT skin model
( Ji Young Moon ),( Jin Hee Lee ),( Eun Ho Maeng ),( Hak Soo Park ),( Min Kwon ),( Dong Hyouk Jang ),( Young Min Cho ),( Eun Ok Koh ),( Ha Jung Sung ),( Cheol Beom Park ) 한국동물실험대체법학회 2007 한국동물실험대체법학회 학술대회집 Vol.2007 No.1
Reconstructed skin give advantages to single cell culture testing system and leads to promising results as be shown in different validation studies. In this study we investigated the efficacy of MCTT Skin model compared with in vivo test. We conducted endpoint analysis including cell viability and IL-1 alpha release. Sodium lauryl sulfate(20%), Potassium hydoxide(5%), Heptanal, Methyl palmitate, 1,1,1-Trichloroethane, 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazol and Benzyl chloroformate were selected for this comparison. Potassium hydoxide(5%) and Benzyl chloroformate were excluded from animal tests because of their pH. Sodium lauryl sulfate induced severe irritation, Heptanal induced moderate irritation. Methyl palmitate, 1,1,1-Trichloroethane induced mild irritation. 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazole induced no irritation on rabbit skin irritation test. Except Methyl palmitate and 2,4-Xylidine, the results were same between MCTT Skin model and in vivo skin irritation test. According to other studies, the results of other skin model and in vivo test of Methyl palmitate and 2,4-Xylidine were shown different result each other. Thus, we concluded that this MCTT Skin model is useful for alternative skin irritation test, although other tests should be conducted for many other chemicals in international validation study.
문지영 ( Ji Young Moon ),맹은호 ( Eun Ho Maeng ),박학수 ( Hak Soo Park ),권민 ( Min Kwon ),장동혁 ( Dong Hyouk Jang ),조영민 ( Young Min Cho ),고은옥 ( Eun Ok Koh ),성하정 ( Ha Jung Sung ),박철범 ( Cheol Beom Park ) 한국동물실험대체법학회 2007 동물실험대체법학회지 Vol.1 No.1
Reconstructed skin provides advantages to single cell culture testing and leads to promising results as shown by different validation studies. In this study we investigated the efficacy of MCTT Skin model compared with EPI-200 and in vivo test. We conducted endpoint analysis including cell viability (MTT reduction, CCK-8) and IL-1 alpha release. Sodium lauryl sulfate(20%), Potassium hydoxide(5%), Heptanal, Methyl palmitate, 1,1,1-Trichloroethane, 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazol and Benzyl chloroformate were selected for this comparison. Potassium hydoxide(5%) and Benzyl chloroformate were excluded from animal tests because of their pH. Sodium lauryl sulfate induced severe irritation, Heptanal induced moderate irritation. Methyl palmitate, 1,1,1-Trichloroethane induced mild irritation. 2,4-Xylidine, 3,3`-Dithiodipropionic acid, 4-Amino-1,2,4-triazole induced no irritation on rabbit skin irritation test. Results of MTT assay and CCK-8 assay were not different between EPI-200 MCTT Skin model but IL-lα levels of some test items different between EPI-200 and MCTT Skin model. We concluded that this MCTT Skin model is useful for alternative skin irritation test, although other tests should be conducted for many other chemicals in international validation study.