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고지혜 ( Ko Ji-hye ) 고려대학교 민족문화연구원 2021 民族文化硏究 Vol.90 No.-
이 논문은 1960년대 조지훈의 학술 활동을 조감하고 당대의 담론 지형 안에서 그 위치를 가늠해 보면서 ‘학인 조지훈’을 역사화하는 작업을 수행하고자 한다. 1964년에 조지훈은 단독저서 1권과 공동저서 2권을 출간하고 잡지 및 학술지에 3편의 논고를 발표 했으며, 고려대학교 민족문화연구소 소장으로서 학술지 『민족문화연구』를 창간하고, 『한국문화사대계』를 기획 및 출간했다. 이러한 조지훈의 학술 활동은 민족이라는 주체의 삶을 이루는 ‘거의 모든 지식’을 체계화하는 작업, 이른바 ‘학(學)으로서의 민족문화’를 수립하는 것으로 수렴된다. 즉, 조지훈은 ‘민족지 구축’과 ‘민족문화사 다시 쓰기’라는 방법론을 통해 민족문화학을 세우고자 했는데, 이러한 작업의 배면에는 면면히 이어 왔어야 할 단일민족의 전통과 문화가 제대로 계승되지 못했다는 문제의식이 자리하고 있었다. 1920년대생 조지훈의 학술 활동은 언제나 ‘일본’ 혹은 ‘식민의 경험’을 의식할 수 밖에 없었기에, 결국 조지훈이 몰두했던 것은 식민사학이 그토록 부정했던 ‘단일한 실체로서의 국가/민족’이 상정되고 작용될 수 있는 지식체계를 만드는 일이었으며, 이러한 ‘탈식민을 위한 욕망’이야말로 학인 조지훈을 추동하던 원동력이었다고 할 수 있다. 이러한 조지훈의 탈식민 민족문화학에 대한 구상은 식민지 조선학운동의 연구 성과에 기반을 둔 것이었다. 특히 최남선의 학술적 작업을 상당 부분 계승하고 있는 조지훈의 작업은 우리 민족문화(사)에 내재해 있는 인류의 보편적 가치를 계승하고 발현시키는 학술 활동이야 말로 민족의 독자성과 존재 가치를 확인하는 작업이라는 인식을 전제한다. 이는 1960년대 후반 본격적으로 논의되기 시작하는 내재적 발전론의 역사인식이기도 했다. 즉, 조지훈은 민족을 주체로 하는 ‘계보의 서사’를 상상하고 창출하는 작업을 수행하고자 했으며 이러한 작업에는 보편에의 충동, 달리 말하면 한국문화사/문학사에도 형이상(사상)이 있음을 증명해내고픈 욕망이 잠재해 있다. 이는 식민과 탈식민이 교차하고, 분단과 냉전체제 안에서 치열한 담론 투쟁이 일어나던 1960년대의 시대정신이기도 하며, ‘한국적인 것’을 탐구하고 찾아내야 했던 (한)국학 연구자로서의 자기정립을 향한 의지이기도 했다. This study aims to examine scholar Cho Ji-hoon in terms of historical context by seeing the entire view of his academic activities in the 1960s and estimating the position within the discourse arena of that time. In 1964, Cho Ji-hoon published one single-authored book, two co-authored books, and three research papers in periodical and academic journal, issued the academic journal Korean Culture Studies as the Research Director of the Institute of Korean Studies, Korea University, and planned and published An Outline of the Korean Civilization. His academic activities are converged into establishing the project of systemizing ‘almost all knowledge’ that comprise the life of ethnic group, so-called ‘national culture as academic studies’. In other words, he tried to establish national culture studies by ‘establishing ethnography’ and ‘rewriting national culture studies’. There underlain the problem consciousness that tradition and culture of a single race, which should have been passed on continuously, were not properly succeeded. Since the academic activities of Cho Ji-hoon who was born in the 1920s had no other choice but to rely on either ‘Japan’ or ‘colonial experience’, he focused on making a knowledge system that can introduce and apply ‘country and race as a single substance’, which was totally denied by the colonial academia. Such a desire for decolonization was an impetus for him. When it came to study contents and methodology, he substantially succeeded the academic projects of the 1920s colonial era Joseonhak movement, especially Choi Nam-seon. Here underlain the thinking that academic activities succeeding and manifesting mankind’s universal value inherent in the Korean ethnic culture history is the project of identifying race’s identity and existence value. This was the historical awareness of the intrinsic development which began to be discussed from the late 1960s. In other words, Cho Ji-hoon aimed to conduct the work of imagining and creating ‘description of genealogy’ which became the root of nation. Here underlain universality orientation―desire to prove that metaphysics exist in Korean culture and literature history. This is the spirit of the 1960s when colonization and decolonization combined and fierce discourse struggle took place in division and the Cold War and the will toward establishing oneself by researchers of Korean Studies who had to explore and discover ‘Korean things’.
7분 선별검사(7 Minute Screen Test) 각 하위 척도의 임상적 유용성
구형모,김지혜,고선규,고혜정,이형석,김상윤,김도관 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.2
Objectives : We aimed to provide standard data of the individual tests in 7MS that could generalized for Korean elderly accor-ding to age and education. We also evaluated diagnostic efFicacy of each test in 7MS. Methods : Data on demographic characteristics of 311 normals were gathered for comparison. We also assessed two differences between normal and dementia group in individual tests of 7MS. Results : All individual tests of 7MS showed significant differences in sex, age, and education, except for ECR. But there were no significant differences in sex controlling age and education. As a result of ROC curve, the ability of the ECR test to discriminate between AD and normal subject appeared superior. The scores of the individual tests of 7MS among CDR 0.5 and 1 group and normal group were compared. It was also found that the ECR test stands out among 7MS tests. Conclusion : The 7MS, Particularly ECR, had the highest sensitivity and specificity for diagnosis of AD as well as early de-mentia. It suggests that the individual tests of 7MS are useful to predict early dementia, without using the complex logistic re-gression equation.
Hye Hyeon Yun,Ji-Ye Baek,Gwanwoo Seo,Yong Sam Kim,Jeong-Heon Ko,Jeong-Hwa Lee 대한약리학회 2018 The Korean Journal of Physiology & Pharmacology Vol.22 No.4
The expression of BCL-2 interacting cell death suppressor (BIS), an antistress or anti-apoptotic protein, has been shown to be regulated at the transcriptional level by heat shock factor 1 (HSF1) upon various stresses. Recently, HSF1 was also shown to bind to BIS, but the significance of these protein-protein interactions on HSF1 activity has not been fully defined. In the present study, we observed that complete depletion of BIS using a CRISPR/Cas9 system in A549 non-small cell lung cancer did not affect the induction of heat shock protein (HSP) 70 and HSP27 mRNAs under various stress conditions such as heat shock, proteotoxic stress, and oxidative stress. The lack of a functional association of BIS with HSF1 activity was also demonstrated by transient downregulation of BIS by siRNA in A549 and U87 glioblastoma cells. Endogenous BIS mRNA levels were significantly suppressed in BIS knockout (KO) A549 cells compared to BIS wild type (WT) A549 cells at the constitutive and inducible levels. The promoter activities of BIS and HSP70 as well as the degradation rate of BIS mRNA were not influenced by depletion of BIS. In addition, the expression levels of the mutant BIS construct, in which 14 bp were deleted as in BIS-KO A549 cells, were not different from those of the WT BIS construct, indicating that mRNA stability was not the mechanism for autoregulation of BIS. Our results suggested that BIS was not required for HSF1 activity, but was required for its own expression, which involved an HSF1-independent pathway.
P219 : The efficacy of laser treatment in postoperative thyroidectomy scars
( Hye Soo Ko ),( Seung Dohn Yeom ),( Jong Hyuk Moon ),( Min Ji Kang ),( Gwang Seong Choi ),( Jeonghyun Shin ),( Ji Won Byun ) 대한피부과학회 2014 대한피부과학회 학술발표대회집 Vol.66 No.2
Background: The cosmetic outcome of the scar after thyroidectomy is important. However, there is no consensus as to what the optimum approach to laser treatment should be. Objectives: To evaluate the efficacy and safety of laser treatment in postoperative thyroidectomy scars. Methods: 52 Korean female patients with thyroidectomy scars underwent several sessions of laser treatment with the pulsed dye laser and/or the ablative fractional laser. Results: Vancouver scar scale(VSS) scores were statistically significantly decreased after laser treatment (p=0.010). The degree of improvements was not significantly associated with mean scar age and the existence of erythema and telangiectasia. Conclusion: Our results suggest that the outcome of laser treatment after thyroidectomy is not affective by the time to treatment.