Production and characterization of soluble human TNFRI-Fc and human HO-1(HMOX1) transgenic pigs by using the F2A peptide

Park, Sol Ji,Cho, Bumrae,Koo, Ok Jae,Kim, Hwajung,Kang, Jung Taek,Hurh, Sunghoon,Kim, Su Jin,Yeom, Hye Jung,Moon, Joonho,Lee, Eun Mi,Choi, Ji Yei,Hong, Ju Ho,Jang, Goo,Hwang, Joing-Ik,Yang, Jaeseok,Le Springer-Verlag 2014 Transgenic research Vol.23 No.3

소뇌 출혈을 동반한 침입성 부비동 아스페르길루스증 1예

양현덕,박성욱,손일홍,이지용,석승한,조광호,이성수 圓光大學校 醫科學硏究所 2003 圓光醫科學 Vol.18 No.2

치면열구전색제와 유동성 복합 레진의 미세 경도 및 표면 조도의 비교

양규호,최남기,김선미,최지은 大韓小兒齒科學會 2009 大韓小兒齒科學會誌 Vol.36 No.3

본 연구는 예방적 레진 수복술에 전통적으로 사용되던 소와열구 전색제를 대신하여, 유동성 복합 레진이 사용될 경우의 타당성을 검토하기 위해 시행되었다. 비커스 미세경도를 측정하기 위해 직경 10 mm, 높이 3 mm인 11개의 시편을 제작하여 비커스 미세경도 측정기(FM-7, FUTURE-TEC Inc., Japan)를 이용하여 압입하중 50 gf, 유지시간 15초의 조건 하에서 측정하여 각 군의 평균값을 산출하였다. 표면조도를 측정하기 위해 칫솔마모시험기(Toothbrush abrasive machine K236, Tokyo Machine Co., Japan)로 4개의 시편 표면에 200 rpm의 속도로 4000회의 칫솔질을 시행한 뒤 표면조도형상측정기(Form Tahrsurf series 2, Rank Taylor Hobson Co., England)를 이용해 표면조도를 측정하였다. α=0.05의 유의 수준에서 Kruskal-Wallis rank test와 Mann-Whitney U test를 사용하였다. 또한 주사전자현미경으로 관찰하여 각 군의 마모 양상을 비교하여 다음과 같은 결론을 얻었다. 1. 비커스 미세경도 측정 결과 Filtek Z350 flowable(3M ESPE, U.S.A), Palfique Estelite LV(Tokuyama Dental, Japan), Ultraseal XT plus(Ultradent, U.S.A) 순으로 높게 나타났으며 모든 군 간에 통계적으로 유의한 차이가 있었다(p<0.0001). 2. 표면 조도 측정 결과, Ultraseal^(R), Estelite^(R), Z350^(R) 순으로 높게 나타났으나 통계적으로 유의한 차이는 없었다(p=0.116). 3. 마모되지 않은 표면과 마모가 일어난 표면을 주사전자현미경으로 관찰한 결과, 전색제인 Ultraseal XT plus와 유동성 복합레진인 Palfique Estelite LV, 나노필러를 함유한 유동성 복합레진인 Filtek Z350 flowable이 서로 다른 마모 양상이 나타나는 것을 볼 수 있었다. 이상의 결과를 토대로 할 때, 유동성 복합 레진이 전색제에 비해 물성적 측면에서 더 우수한 것으로 나타났다. This study was performed to compare the wear resistance of sealant and flowable resins for analyzing the effect of flowable resin as a sealant in preventive resin restorations. Specimens were made and Vicker's hardness number and surface roughness were measured. SEM observations of the polished and abraded surfaces were established. Kruskal-Wallis rank test and Mann-Whitney U test at the significant level of α=0.05 were used. The following results were obtained: 1. The microhardness was decreased among groups in following order: Z350(3M ESPE, U.S.A), Estelite(Tokuyama Dental, Japan) and Ultraseal(Ultradent, U.S.A). There were significant differences in all groups(p<0.0001). 2. The surface roughness was decreased among groups in following order: Ultraseal XT plus, Palfique Estelite LV and Filtek Z350 flowable, However, there is no statistically significant differences in roughness among Estellite, Z350 and Ultraseal at the significance level of α=0,05, with p=0.116 3. SEM observation of the unworn and worn surfaces revealed the qualitative differences in the wear appearance among groups. The results in this study indicate that flowable resin is better than sealant in aspect of physical properties.

조사연구에서 표본설계에 대한 고찰

양철호,양선화,신봉관,조지현 동신대학교 2005 論文集 Vol.15 No.-

Most of the survey research are conducted with samples. Thus, representativeness of the samples is crucial for the sound research. Reports of the various survey research were analized. The results of the analysis showed that different ways of sampling methods were utilized in various studies in order to ensure the selection of unbiased samples under the circumstances of purpose and population of the survey.

McNamara분석법에 의한 Ⅲ급 부정교합 아동의 두부방사선 계측학적 연구

양규호,김지영,최남기 대한소아치과학회 2001 大韓小兒齒科學會誌 Vol.28 No.3

정상교합아동과 비교적 조기치료가 요구되는 Ⅲ급 부정교합을 갖는 성장기 아동에서 측모 두부 방사선 계측치의 평균치를 산출하여 진단 및 치료계획 수립에 도움이 되고자 전남대학교병원 소아치과에 내원한 7세에서 9세사이의 17급 부정교합 아동 83명과 안모가 단정하고 정상교합을 갖는 광주지역 초등학생 84명을 대상으로 측모 두부 방사선촬영을 하여 McNamara분석법을 이용한 계측치를 비교 분석하여 다음과 같은 결론을 얻었다. 1. 남아에서 정상교합자와 Ⅲ급 부정 교합자간의 계측치에서 Effective maxillary length.Maxillomandibular differential, Facial axis, Nasion perp to pogonion, Point A perp to Mx 1, A-Pog line to Mn 1의 항목이 유의성 있는 차이를 나타내었다(p<0.01) 2.여아에서 정상교합자와 Ⅲ급 부정교합자간의 계측치에서 Nasion Perp. to Point A(p<0.05), Erective Mandibular lengh, Effective Maxillary lengh, Maxillomandibular differential, Mandibular plane angle, Point A perp to Mx 1, A-Pog line to Mn 1의 항목이 유의성 있는 차이를 나타내었다(p<0.01). 3. Effective Mandibular lengh는 남아에서 정상교합자와 Ⅲ급 부정교합자간에 차이가 없었으나, 여아에서는 유의한 차이가 있었다(p<0.01) 그러나 Effective Maxillary lengh는 Ⅲ급 부정교합자가 남녀 모두에서 정상교합자보다 유의성 있게 짧았다(p<0.01) . 4. Anterior lower facial height는 남녀 모두 정상교합자와 Ⅲ급 부정교합자의 비교에서 유의한 차이가 없었다 7. 남아와 여아의 계측치 비교에서 Anterior lower facial height와 Mandibular plane angle은 정상교합자와 Ⅲ급 부정 교합자 모두에서 유의한 차이가 있었다(p<0.01) . In the growing children with normal occlusion and class Ⅲ malocclusion who need the early treatment to be helped to diagnose and to set up treatment plan by calculating the mean values of the lateral cephalometric measurements, cephalometric measurements by McNamara alalysis were achieved and compared on both the 84 elementary school children with normal occlusion and 83 class Ⅲ malocclusion children at the age of 7 to 9 in Kwangju city and the results were as follows : 1. On the boys group, between normal occlusion and class Ⅲ malocclusion, Effective maxillary length, Maxillomandibular differential, Facial axis. Nasion perpendicualr to pogonion, Point A perp to Mx 1, and A-Pog line to Mn 1 showed significant differences(p<0.05) . 2. On the girls group, between normal occlusion and class Ⅲ malocclusion significant differences were shown in Effective Maxillary length, Maxillomandibular differential, Mandibular plan angle, Nasion perpendicular to Point A, Point A perp to Mx 1 A-Pog line to Mn 1(p<0.01). 3 There were no significant differences between normal occlusion and class Ⅲ malocclusion of boys group but siginificant differences between them of girls group in Effective mandibular length(p<0.01), On the boys and girls group, Effective maxillary length of class Ⅲ malocclusion was shorter than that of normal occlusion. 4. There were no significant differences between normal occlusion and class Ⅲ malocclusion both in boys and girls at Anterior lower facial height. 5. There were significant differences between boys and girls both in class Ⅲ malocclusion and normal occlusion at Anterior lower facial height and Mandibular plane angle(p<0.01) .

액상요구르트의 沈澱安定化를 위한 硏究

양지영,이호재 釜山工業大學校 1994 論文集 Vol.36 No.-

In order to process the liquid yogurt without stabilizing agents, addition of rice bran extracts to medium, single or mixed cultures of various lactic acid bacteria were investigated. Addition of rice bran extracts stimulated acid production and propagation of L. casei N.Y. and its optimum concentration was 0.1%. Cultures prepared using 0.1% of rice bran extracts could be produced stable liquid yogurt product without stabilizing agents. But the use of rice bran extracts to liquid yogurt manufacture in a pilot scale was problematical in view of cost and law. The single or mixed cultures of L.casei L-14 and L. bulgaricus B-5b couldn't be produced stable product without stabilizing agents. L. casei J.Y. was produced 2.7 of acidity at 37℃ for 36 hrs to obtain cultures with high acidity and high number of viable cells. The liquid yogurt product prepared using cooled cultures of L. casei J.Y. was stable without stabilizing agents. But the liquid yogurt product prepared using stabilizing agents was unstable because of charge imbalane.

AB 슬라이드, 크런치 및 윗몸일으키기 운동이 복직근 근활성도에 미치는 효과 : Comparison of It `s Myoelectrical Activities with Crunch and Sit-Up

지송운,김호성,양윤준,장재원 대한스포츠의학회 2004 대한스포츠의학회지 Vol.22 No.1

The purpose of this study was to compare the effect of AB slide™ on abdominal muscles with Crunch and Sit-up. Myoelectrical activities of Rectus abdominis muscles produced by AB slide™, Crunch and Sit-up were recorded. Healthy male aged from 17 to 36 years(23.0±5.9 yrs) were included fo the test. Surface electrodes were attached to upper and lower part of Rectus abdominis of the study subjects. Averaged integrated electromyography(AIEMG) and Normalized integrated electromyography(NIEMG) were recorded. The results are summarized as follows; First, the AIEMG of Sit-up were highest among them with insignificant difference statistically. Second, the NIEMG of upper part of Rectus abdominis were higher than the one of lower part with significant difference statistically(p<0.05). This phenomenon was same irrespective of the type of exercises. AB slide™ was not more effective than Sit-up and Crunch for strengthening of Rectus abdominis muscle. The upper part of Rectus abdominis was more activated than the lower part by all three exercises.

Sagittal appliance를 이용한 부정교합의 치료에 관한 증례

양규호,김지영,오희수 大韓小兒齒科學會 1991 大韓小兒齒科學會誌 Vol.18 No.2

Sagittal appliance is an active plate with expansion screws in the anteroposterior direction.It is used to advance the maxillary incisors and to distalize the maxillary molars,thereby to increase arch length. Sagittal appliance produces changes of tooth position in the surrounding bone by converting mechanical pressure into biological energy as the screws are activated regularly. We treated anterior crossbite,severe crowding,and submerged tooth with sagittal appliance. The results were as follows: 1. Dental crowding was relieved by some advancement of incisors and most of distalization of molar after extraction of second molars. 2. Anterior cross bite caused by immaturity of premaxilla was corrected by advancement of maxillary incisors and premaxilla and then facial profile was improved. 3. Irregular tooth arrangement and labial inclination of incisors occured during treatment will be corrected by fixed appliance. 4. Mesially titled first molar caused by submerged second primary molar was uprighted and lost space of secondprimary molar was regained by lower unilateral sagittal appliance.

Cone-beam CT를 이용한 제II급 부정교합 아동의 상기도 형태에 관한 3차원적 연구

홍지숙,김대성,오경민,김윤지,이규홍,박양호 대한치과교정학회 2010 대한치과교정학회지 Vol.40 No.3

Objective: The aim of this study was to evaluate the volumes and areas of the upper airways in children with Class II malocclusion, using three dimensional cone-beam computed tomography (CBCT) and to compare the volumetric and cross-sectional measurements and cephalometric variables to investigate possible relationships between the upper airway and facial morphology. Methods: CBCT scans were obtained from 37 subjects (17 boys and 20 girls; average age, 11.02 years). The upper airway volumes and areas were measured, and compared with cephalometric variables. Results: The area of the PNS-posterior plane (SPP) was significantly smaller in the Class II malocclusion group (p < 0.05). Also, the volumetric and cross-sectional measurements were lower in Class II than in Class I malocclusion groups, although the differences were not significant between the two groups (p > 0.05). The Class II malocclusion group showed significantly smaller values of PFH, mandibular body length, pog to N perp and showed larger values of FMA, ANB, and facial convexity than the Class I malocclusion group. The volume of the upper airway in front of PNS point (WN) showed negative correlation with ANB (p < 0.05). Conclusions: The Class II malocclusion group had a narrower upper airway associated with a decreased posterior facial height and a divergent growth pattern than the Class I malocclusion group. 성장기 아동의 상기도 협착은 두개안면 성장에 영향을 미칠 수 있다. 본 연구는 3차원 cone-beam computed tomography (CBCT)를 이용하여 제II급 부정교합 아동의 상기도 부피 및 단면적 계측치와 측모두부계측치를 비교하여 상기도와 안면 형태와의 연관성을 알아보고자 하였다. 37명의 아동(남자 17명, 여자 20명, 평균 연령 11.02세)의 CBCT를 촬영하였다. 연구 결과, 상기도의 PNS-posterior plane에서의 단면적(S_(PP))은 제II급 부정교합군에서 유의하게 작았다 (p < 0.05). 상기도 부피 계측치는 제II급 부정교합군에서 제I급 부정교합군보다 작았으나, 두 군 간 통계적으로 유의한 차이는 없었다. 제II급 부정교합군은 후안모고경(PFH), mandibular body length (p < 0.05), Pog to N perp (p < 0.01)에서 제I급 부정교합군보다 유의하게 작은 값을 보였고, FMA (p < 0.05), ANB, facial convexity (p < 0.01)는 유의하게 큰 값을 보였다. 제II급 부정교합군의 PNS 전방의 상기도 부피(W_(N))는 ANB difference 각도와 음의 상관관계를 보였다 (p < 0.05). 제II급 부정교합 아동은 상대적으로 좁은 상기도 부피를 가지며 이에 따른 감소된 후안모고경(PFH)과 하악골의 divergent한 안면 성장 양상을 보였다.

전신성 백색증(Oculocutaneous albinism) 환아의 증례 보고

최지은,최남기,김선미,양규호 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

백색증(albinism)이란 신체 내 melanin 합성의 부분적,혹은 완전한 결핍에 의해 일어나는 질환이다. Melanin은 신체 내에서 머리카락,눈,피부 등에 분포하기 때문에 백색증 환자는 밝은 금발이나 갈색의 머리카락과 하얀 피부,붉거나 갈색의 홍채를 갖는 특징적인 외모를 지닌다. 백색증 환자는 변이된 유전자 및 임상적 특징에 따라 크게 전신성 백색증,안성 백색증,부분적 백색증으로 나뉘며 그 밖에 많은 하위군이 존재하고 그에 따른 치료법이나 치과적 주의사항도 달라진다. 본 증례는치아의 발육지연 여부평가를 주소로 내원한정신 지체가 동반된 전신성 백색증 환아로서 치아발거 등의 관혈적 시술및 보존수복,공간유지장치 등의 치료를 통해 양호한 결과를 보였기에 이를 보고하는 바이다. Albinism is a disease caused by partial or complete failure of melanin production in the skin,hair and eyes despite the presence of normal number,structure and distribution of melanocytes. Typical aspects are white-colored skin,blonde-brown hair,blue-brown irides and a prominent red reflex. Three main categories of albinism are oculocutaneous,ocular and localized albinism,and also they are divided into many subgroups. Therefore, appropriate treatment plan and dental direction would be differentiated according to them. This case report was about oral conditions and treatment of the oculocutaneous albinism patient with mental retardation who was refered due to developmental delay of teeth and treated with teeth extraction,restoration and space maintenance etc.