Structural features of influenza A virus panhandle RNA enabling the activation of RIG-I independently of 5′-triphosphate

Lee, Mi-Kyung,Kim, Hee-Eun,Park, Eun-Byeol,Lee, Janghyun,Kim, Ki-Hun,Lim, Kyungeun,Yum, Seoyun,Lee, Young-Hoon,Kang, Suk-Jo,Lee, Joon-Hwa,Choi, Byong-Seok Oxford University Press 2016 Nucleic acids research Vol.44 No.17

<P>Retinoic acid-inducible gene I (RIG-I) recognizes specific molecular patterns of viral RNAs for inducing type I interferon. The C-terminal domain (CTD) of RIG-I binds to double-stranded RNA (dsRNA) with the 5′-triphosphate (5′-PPP), which induces a conformational change in RIG-I to an active form. It has been suggested that RIG-I detects infection of influenza A virus by recognizing the 5′-triphosphorylated panhandle structure of the viral RNA genome. Influenza panhandle RNA has a unique structure with a sharp helical bending. In spite of extensive studies of how viral RNAs activate RIG-I, whether the structural elements of the influenza panhandle RNA confer the ability to activate RIG-I signaling has been poorly explored. Here, we investigated the dynamics of the influenza panhandle RNA in complex with RIG-I CTD using NMR spectroscopy and showed that the bending structure of the panhandle RNA negates the requirement of a 5′-PPP moiety for RIG-I activation.</P>

전통시장 내 소매경쟁이 임대료에 미치는 영향에 관한 연구

이철성 ( Lee Chul Sung ),김장현 ( Kim Janghyun ) 한국유통경영학회(구 한국유통정보학회) 2018 유통경영학회지 Vol.21 No.5

기존 전통시장에 대한 정부 정책은 대형유통업체와의 경쟁으로 인하여 전통시장의 매출감소를 방지하고 지역 경제의 기반을 유지하고 활성화시키기 위한 측면에서 이루어졌다. 그러나 대형유통업체는 SSM 및 상품공급점, 식자재 마트 등과 함께 최근에는 편의점을 통해 전통시장에 입점하고 있는 현실이다. 이러한 대형유통업체로 인한 전통시장잠식은 매출하락에 영향을 미치며, 장기적으로는 부동산 가치의 하락을 야기하여 전통시장이 사라질 수 있음을 의미한다. 그러나 소매경쟁의 측면에서 이에 대한 연구는 부족한 실정이다. 그러나 이에 대한 연구는 부족한 실정이다. 따라서 본 연구에서는 이철성, 김영기, 김승희(2018)과 김승희, 이철성, 김영기(2018)의 연구를 바탕으로 전통시장의 소매경쟁과 임대료의 관계를 살펴보려 한다. 이를 위하여 소상공인시장진흥공단과 한국감정원의 자료를 바탕으로 이들간의 관계를 실증분석하였다. 연구 결과는 다음과 같다. 첫째, 전통시장 내 SSM 및 상품공급점의 입점은 점포의 단위면적당 임대료를 낮추는 것으로 나타났다. 이러한 연구결과는 기존 김승희, 이철성, 김영기(2018)의 연구결과에서 이들 업체의 입점이 전통시장의 공실률에 부정적인 영향을 미친다는 결과와 일치한다. 둘째, 전통시장 내 하나로 마트의 입점은 점포 임대료에는 영향을 미치지는 것으로 나타났다. 이러한 연구결과는 하나로 마트가 유통산업발전법 제외 대상이나 실질적으로 대형유통업체로 간주해야 하며, 전통시장에 부정적인 영향을 미치고 있음을 의미한다. 마지막으로 전통시장 내 식자재 마트와 기타 마트의 입점은 점포 임대료에 영향을 미치지 않는 것으로 나타났다. The government policy on the traditional market has been made in order to prevent the decrease of sales in the traditional market due to competition with large retailers and to maintain and activate the foundation of local economy. However, large retailers have recently entered the traditional market through convenience stores, commodity supply stores, and food materials mart. Recently, it has been opened through convenience stores. Traditional market erosion caused by these large distributors affects sales decline, and in the long run, it may lead to a decline in real estate value and the traditional market may disappear. However, research on retail competition is lacking. Therefore, this study will examine the relationship between retail competition and rent in traditional markets based on the researches of Lee Chul-sung Kim Young ki, Kim Seung-hee (2018) and Kim Seung-hee, Lee Chul-sung and Kim Young-ki (2018). For this purpose, we conducted empirical analysis on the relationship between them based on the data of the market promotion corporation and the Korean appraisal agency. The results of the study are as follows. First, SSM and commodity supply store in traditional markets lower rent per unit area of stores. These findings are consistent with the findings of Kim Seung-hee, Lee Chul-sung, and Kim Young-ki (2018) that the entry of these firms negatively affects the vacancy rate of traditional markets. Second, Hanaro mart's entry has a negative effect on store rents. These results imply that Hanaro Mart should be regarded as a large-scale retailer or a target to be excluded from the retail industry development law and has a negative impact on the traditional market. Finally, it was found that the number of food materials mart and other mart in traditional markets did not affect store rents.

GROTESQUE IMAGERY ENHANCING PERSUASIVENESS OF LUXURY BRAND ADVERTISING

Donghwy An,Chulsung Lee,Janghyun Kim,Nara Youn 글로벌지식마케팅경영학회 2017 Global Fashion Management Conference Vol.2017 No.07

Have you ever seen images of an elegant woman dressed in period clothes, threatening to stab another woman through the neck; a model facing a leopard behind a mannequin hand; or a lady using a hook to fish a purse out of a pool, while a seemingly dead man is floating in the water? The descriptions of these scenes might sound dark and absurd, and provoke disgust or displeasure; but the fact is, these images have been used in real advertisements for prestigious fashion brands such as Gucci and Dolce & Gabbana, and were featured heavily in various fashion magazines. Recently, advertisers have sought to differentiate their products by using grotesque imagery in their ads as a strategy to get consumers’ attention and stimulate their curiosity. Although growing attention is being paid to ads that are not conventionally ‘pretty’, very little research has tried to empirically document the effect of grotesque imagery on the persuasiveness of luxury brand advertising, or unveil the psychological mechanism underlying the effect. The purpose of this research is to investigate how grotesque imagery used for luxury products appeal to consumers, and why the ads affect the consumers’ behavior. We empirically demonstrated that the grotesque imagery used to promote luxury products enhances consumers’ purchase intention because it facilitates consumers to better experience the brand by transporting them to the narratives that are portrayed in the ads. This process occurs because a correspondence between grotesque imagery and luxury branding generates the fit effect, which leads to fluent processing and feel right experience, and in turn induces engagement to the ad. Grotesque Advertisement Grotesque was the word indicating the style of ancient decoration that depicted fantastic combinations of human and animal forms, interwoven with strange fruits and flowers. The Cambridge Dictionary of English now defines grotesque as a general adjective that describes anything “very strange and unpleasant, especially in a ridiculous or slightly frightening way.” Evolutionary psychology provides us a hint for the reason why emotionally provocative and fear-evoking grotesque imagery captures consumers’ attention. The faster attention to negative stimuli than to positive stimuli is an automatic tendency developed as means of evolutionary adaptedness for survival because negative stimuli signal danger and cause alert to prompt defensive reaction (Ohman, Flykt and Esteves, 2001; Schoemaker 1996; Tan 2008). Another explanation for grotesque imagery’s attention grabbing power arises from our complex emotional system—i.e. human enjoys fearful horror or heartbreakingly sad films, because such negative emotions often stem from a challenging situation filled with risks, threats, and tension and generate an active interest in it (Bartsch, Apple and Stroach 2010; Oliver 1993; Tan 2008). Frightening, disgusting, or tragic emotions are mixed with a relief that comes after a perception of reality. Because human has an ability to distinguish their real life and the situation in the film or drama, we feel interests while being frightened or disgusted or heart-broken with pleasurable enjoyment (Tan 2008). Prior research by Phillips and McQuarrie (2010) brought to light the concept of grotesque in the context of fashion marketing. They described grotesque imagery using words with common etymological meanings—bizarre, surreal, deviant, absurd, discrepant, peculiar, and odd—and suggested that it could lead viewers to engage in the ad through transportation or immersion to the story world of the ad. Through the narrative transportation, grotesque imagery persuades consumers to better experience the brand featured in the ad. Based on their conceptualization of grotesque and its persuasive power, we empirically test whether grotesque imagery used in an ad might work as a strong trigger of fantasy, stimulating viewers to be transported into the narrative depicted in the ad image. Transportation Transportation is defined as ‘a convergent process where all mental systems and capacities become focused on events occurring in the narrative’ (Green and Block 2000, p. 701); it represents the extent of absorption into the narrative flow of the story as it unfolds. Transportation occurs whenever the consumer experiences a feeling of entering a world brought to mind by the story, because of their empathy for the story characters and imagination of the story narratives (Van Laer et al. 2014). Previous research suggests that transportation induces favorable attitudes toward the related product (Escalas 2004), and enhances the persuasiveness of advertising messages through the connection between the self and the ad content (Escalas 2004). Fit Between Grotesque Imagery and Luxury Branding The effect of fit, which means a relevant and logical connection between ad contents, has been widely studied in advertising and marketing literature. Fit messages are readily accessible, and processed through simple cognitive information processes. Macinnis and Park (1991) argue that the fit effect is caused by consumers’ perception of the stimuli in ads as a whole, rather than distinct individual elements. The processing of fit (vs nonfat) messages is easier, so more fluent (Lee and Aaker 2004; Labroo and Lee 2006), and fluent processing of fit messages offer a feel right experience (Camacho, Higgins, and Luger 2003; Lee, Keller, and Sternthal 2009). This subjective experience of feeling right increases engagement (Lee, Keller, and Sternthal 2009), willingness to pay, favorability of brand attitudes, and brand choice (Lee and Higgins 2009). In this research, we posit that persuasive effect of grotesque ads is more likely to occur when grotesque imagery is used for advertising luxury brands. Previous research explained the motivations to purchase luxury brands as scarcity, uniqueness, distance, high price (Dion and Arnould 2011; Dubois and Duquensne, 1993), and signaling of social status (Belk 1988; Zhou and Belk 2004; Han, Nunes, and Dr?ze 2010), which intersect with the characteristics of grotesque. People purchase luxury goods because they are relatively exclusive and limited, providing the consumer with more emotional distance from mass produced products (Hansen and W?nke 2011). In addition, positioning a brand using mythical and abstract concepts is known to be more effective in building strong prestigious brands (Arsel and Craig 2011). Because grotesque is perceived to be distant from reality, incongruent, and discrepant, these characteristics of luxury branding could overlap with that of grotesque. Furthermore, support for our prediction of a fit between grotesque imagery and luxury branding can be found in some other common features of both. Dion and Arnould (2011) argue that luxury brands possess hedonic appeals based on multisensorial pleasure, artistic aura, and charismatic stories which transport consumers into the magical world of the luxury brand. In support, Kim, Lloyd and Cervellon (2015) found that luxury brand advertising stimulates fantasy, and this is one of the dominant themes through which consumers were engaged with the brand. They showed that being part of the narratives in the ads, participants experienced escaping from their everyday lives, traveling around the fantasy world, and feeling that their myth, fantasies or dreams become real. As luxury brand advertising has a power to transport consumers into fantasy, grotesque imagery also carries consumers away into magical world through narrative transportation (Phillips and McQuarrie 2010). Hypotheses In light of the prior research, we posit that when grotesque imagery is used in ads for luxury brands, the fit generates feel right experience and easy and fluent processing of messages, because grotesque imagery and luxury brand advertising commonly have a power to transport viewers to fantasy world distant from reality. In addition, previous research has suggested positive downstream effects for transportation to enhanced brand experience. As the level of experience is enhanced, familiarity and satisfaction with the brand are heightened as well (Ha and Perks 2005). A deeper level of brand experience generates brand trust and accelerates loyalty to brands (Lglesias, Singh, and Batista-Goguet 2011). Thus, we propose the following hypotheses: H1: Luxury brand advertising with grotesque imagery will facilitate transportation, which will in turn enrich brand experience and increase purchase intention of the featured product. H2: There will be a perceived fit between grotesque imagery and luxury branding. H3: The fit between grotesque imagery and luxury branding will enrich brand experience which in turn enhance purchase intention. Study 1 The goal of Study 1 was to show that a grotesque ad is perceived to be better-matched with brands described as prestigious. Stimuli. We designed two versions of a print advertisement for a fictitious fashion brand to manipulate grotesque (vs. non-grotesque) ad style. We created the ad by modifying the content from an existing Jimmy Choo advertisement. The print ad featured a man, a girl, a car, and a handbag placed in the middle of a desert. In the grotesque imagery condition, the girl is placed in the truck of a car, appearing dead since the man sitting next to her is holding a shovel that he seemingly used to dig a hole in the ground to bury her. In the non-grotesque imagery condition, we replaced the shovel to a cane. In the prestige condition, we introduced the brand as one with a prestigious image similar to those of Louis Vuitton and Hermes. In the non-prestige condition, the brand was described as having a brand image similar to Zara and H&M. Procedure. 171 undergraduates (average age = 22.8 years; 171 females) participated in the study for a course credit. Participants were informed that they would be asked to complete an ad evaluation study, and were randomly assigned to be presented with one of the four print ads featuring a handbag. Participants were asked to indicate how likely they would be to purchase the handbag product (1 = very unlikely; 7 = very likely), and how well-matched the ad is to the product and the brand image on two items (‘the ad goes nicely together with the handbag’ ‘the ad looks well-matched with the image of the brand’; 1 = not at all ~ 7 = very much). Then, they completed two item transportation measures (‘While I was looking at the ad, I could easily picture the events in it taking place,’ ‘I had a vivid image of the man sitting next to the woman’; 1 = strongly disagree ~ 5 = strongly agree) adapted from Green and Brock (2000). Next, participants responded to twelve items of brand experience measure from Jos ?ko Brakus, Schmitt, and Zarantonello (2009) (e.g. ‘This brand results in bodily experiences’, ‘This brand stimulates my curiosity and problem solving’; 1 = strongly disagree ~ 7 = strongly agree). They also rated how grotesque the ad was on seven items (‘bizarre,’ ‘surreal,’ ‘deviant,’ ‘absurd,’ ‘peculiar,’ ‘odd’, ‘discrepant’; 1 = not at all ~ 7 = very much). To rule out an affective account for participants’ evaluation, we assessed participants’ mood (1 = negative mood, bad mood, sad, irritated ~ 7 = positive mood, good mood, happy, relaxed) and their arousal (1 = not at all aroused ~ 7 = very aroused). Results: Perceived fit. The two perceived fit items were averaged to form a fit index. A two (ad style: grotesque vs. non-grotesque) by two (brand reputation: prestige vs. non-prestige) between-subjects ANOVA revealed a significant ad style by brand reputation interaction effect (F(1, 167) = 5.69, p = .018). Planned contrasts indicated that, in the grotesque imagery condition, participants rated the ad as more well-matched when the product was described as a prestigious brand (M = 4.14) than when it was a non-prestigious brand (M = 3.53; F(1, 167) = 4.15, p = .043). In contrast, in the non-grotesque imagery condition, participants rated the ad as less well-matched when it was described as a prestigious brand (M = 3.60) rather than non-prestigious brand (M = 4.00), but the effect was not significant (F(1, 167) = 1.79, p = .183). Because the perceived fit results confirmed that participants rated the ad as more well-matched when the product was described as a prestigious brand, we created an imagery fit variable coding the well-matched conditions (grotesque imagery for prestige brand and non-grotesque imagery for non-prestige brand) to be 1, and the less well-matched conditions (grotesque imagery for non-prestige brand and non-grotesque imagery for prestige brand) to be 0. As predicted, an ANOVA revealed that the well-matched conditions showed higher perceived fit (F(1, 169) = 5.79, p = .017), such that those in the matched condition (M = 4.07) rated higher on perceived fit than those in the mismatched condition (M = 3.57). Transportation. Participants’ ratings on the two transportation items were averaged to form transportation scores. A two way ANOVA revealed a significant ad style (grotesque vs. control) by brand reputation (prestige vs. non-prestige) interaction effect on transportation (F(1, 167) = 4.35, p = .039). Planned contrasts indicated that, in the grotesque condition, participants reported higher transportation scores when the product was described as a prestigious brand (M = 3.22) than a non-prestigious brand (M = 2.78; F(1, 167) = 4.28, p = .040). In contrast, in the non-grotesque condition, participants reported lower transportation scores when it was described as a prestigious brand (M = 2.62) rather than a non-prestigious brand (M = 2.81), but the effect was not significant (F(1, 167) = .78, p = .378). Mediation Effect of Transportation on Brand Experience. Participants’ ratings on the brand experience scale were averaged to form brand experience scores. A series of regressions showed that the ad style by brand reputation interaction activated transportation (β = .632, p = .034), which then yielded greater brand experience (β = .360, p <.001). The bootstrap procedure for a conditional mediation model (PROCESS Model 7; Hayes 2013) using 5,000 samples revealed a significant conditional indirect effect of grotesque imagery on brand experience through activation of transportation when the product was described as a prestigious brand (95% CI [.067, .390]). This conditional indirect effect was not significant when the product was described as a non-prestigious brand (95% CI [–.189, .138]). Multiple Mediation Effect. Our prediction was that grotesque imagery used in luxury brand advertising would lead to higher perceived fit, which facilitates narrative transportation and in turn enhances brand experience leading to greater purchase intention. Multiple mediation analyses using PROCESS Model 6 (Hayes 2013) with 5,000 resamples confirmed that the perceived fit → transportation → brand experience path mediated the effect of imagery fit on purchase intention. The imagery fit variable was created as a binary variable (1 = grotesque imagery for prestige brand or non-grotesque imagery for non-prestige brand; 0 = otherwise). First, the path from imagery fit to perceived fit was significant and positive (? = .504, p = .017), as was the path from perceived fit to transportation (? = .149, p = .007), the path from transportation to brand experience (? = .326, p < .001), and the path from brand experience to purchase intention (? = .344, p = .014). The 95% CI of the bootstrap procedure ([.001, .030]) confirmed that the indirect effect of imagery fit on purchase intention through the three mediators—perceived fit, transportation and brand experience—was significant. Study 2 The objective of Study 2 was to test the robustness of the mediating role of transportation for the effect of grotesque imagery fit with luxury brand. In addition, we checked whether the grotesque manipulation affected the extent to which participants perceived the brand as luxurious. Stimuli. Two versions of print advertisement were created to manipulate grotesque (vs. non-grotesque) ad style by modifying an existing Dolce & Gabbana ad campaign. The print ad featured two women, a man, and handbags placed on the floor of a classically decorated room. In the grotesque imagery condition, one of the girls wearing a ball gown is holding a knife and seemingly about to stab another girl. In the non-grotesque imagery condition, we replaced the knife with a bottle of perfume. All participants were provided with the print ad that contained a cover story about the ad evaluation task, describing the brand as either a prestigious brand that is similar to Louis Vuitton and Hermes or a brand with an image that is similar to Zara and H&M. Procedure. 165 undergraduate students (average age = 23.8; 66 females) were randomly assigned to one of the four experimental conditions. Participants were first asked to indicate how likely they would be to purchase the featured handbags (1 = very unlikely; 7 = very likely). Then, they responded to two transportation items (‘I wanted to learn how the story in the ad ended’, ‘The story in the ad affected me emotionally’, ‘I found myself thinking of ways the story in the ad could have turned out differently’; 1 = not at all ~ 5 = very much). Next, participants responded to the same twelve-item brand experience scale, seven item grotesque measure, four mood items, and an arousal item used in Study 1. In study 2, they were also asked to rate their impression of the product as luxurious, prestigious, and high class (1 = not at all; 7 = very much). Results. The grotesque manipulation did not affect the extent to which participants perceived the brand as luxurious, and when the product was described as a prestigious brand, participants in the grotesque condition reported higher transportation scores than those in the non-grotesque condition. Multiple mediation analyses reconfirmed that the transportation → brand experience path mediated the effect of imagery fit on purchase intention. General Discussion Through two studies, we demonstrated that grotesque ads can be effective in persuading consumers to purchase luxury fashion items. We found that grotesque ads trigger transportation when the brand is described as prestigious, enriching brand experience, and in turn heightening consumers’ purchase intention.

Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies

Lee, Janghyun,Park, Eun-Byeol,Min, Jiyoun,Sung, Si-Eun,Jang, Yejin,Shin, Jin Soo,Chun, Dongmin,Kim, Ki-Hun,Hwang, Jihyun,Lee, Mi-Kyung,Go, Yun Young,Kwon, Dohyeong,Kim, Meehyein,Kang, Suk-Jo,Choi, Byo Oxford University Press 2018 Nucleic acids research Vol.46 No.4

<P><B>Abstract</B></P><P>Retinoic acid-inducible gene I (RIG-I) recognizes double-stranded viral RNAs (dsRNAs) containing two or three 5′ phosphates. A few reports of 5′-PPP-independent RIG-I agonists have emerged, but little is known about the molecular principles underlying their recognition. We recently found that the bent duplex RNA from the influenza A panhandle promoter activates RIG-I even in the absence of a 5′-triphosphate moiety. Here, we report that non-canonical synthetic RNA oligonucleotides containing G-U wobble base pairs that form a bent helix can exert RIG-I-mediated antiviral and anti-tumor effects in a sequence- and site-dependent manner. We present synthetic RNAs that have been systematically modified to enhance their efficacy and we outline the basic principles for engineering RIG-I agonists applicable to immunotherapy.</P>

Systematic editing of synthetic RIG-I ligands to produce effective antiviral and anti-tumor RNA immunotherapies

Lee, Janghyun,Park, Eun-Byeol,Min, Jiyoun,Sung, Si-Eun,Jang, Yejin,Shin, Jin ,Soo,Chun, Dongmin,Kim, Ki-Hun,Hwang, Jihyun,Lee, Mi-Kyung,Go, Yun Young,Kwon, Dohyeong,Kim, Meehyein,Kang, Suk-Jo,Choi Oxford University Press 2018 Nucleic acids research Vol.46 No.19

NMR Tools to Decipher Dynamic Structure of RNA

Lee, Janghyun,Choi, Byong-Seok Korean Magnetic Resonance Society 2017 Journal of the Korean Magnetic Resonance Society Vol.21 No.2

It is now well established that RNAs exhibit fundamental roles in regulating cellular processes. Many of these RNAs do not exist in a single conformation. Rather, they undergo dynamic transitions among many different conformations to mediate critical interactions with other biomolecules such as proteins, RNAs, DNAs, or small molecules. Here, we briefly review NMR techniques that describe the dynamic behavior of RNA by determining structural, kinetic, and thermodynamic properties.

The N terminus of cGAS de-oligomerizes the cGAS:DNA complex and lifts the DNA size restriction of core-cGAS activity

Lee, Arum,Park, Eun-Byeol,Lee, Janghyun,Choi, Byong-Seok,Kang, Suk-Jo Wiley (John WileySons) 2017 FEBS letters Vol.591 No.6

<P>Cyclic GMP-AMP synthase (cGAS) is a DNA-sensing enzyme in the innate immune system. Recent studies using core-cGAS lacking the N terminus investigated the mechanism for binding of double-stranded (ds) DNA and synthesis of 2 ',3 '-cyclic GMP-AMP (cGAMP), a secondary messenger that ultimately induces type I interferons. However, the function of the N terminus of cGAS remains largely unknown. Here, we found that the N terminus enhanced the activity of core-cGAS in vivo. Importantly, the catalytic activity of core-cGAS decreased as the length of double-stranded DNA (dsDNA) increased, but the diminished activity was restored by addition of the N terminus. Furthermore, the N terminus de-oligomerized the 2 : 2 complex of core-cGAS and dsDNA into a 1 : 1 complex, suggesting that the N terminus enhanced the activity of core-cGAS by facilitating formation of a monomeric complex of cGAS and DNA.</P>

SIP 프록시 서버를 위한 우선순위 스케줄링 기반의 과부하 제어 알고리즘

이장현 ( Janghyun Lee ),조인휘 ( Inwhee Joe ) 한국정보처리학회 2011 한국정보처리학회 학술대회논문집 Vol.18 No.2

SIP (Session Initiation Protocol)는 사용자간의 멀티미디어 세션의 초기화, 변경 및 종료를 위한 응용 계층의 시그널링 프로토콜이다. SIP는 실시간 멀티미디어 서비스 통신에 많이 이용되기 때문에 주로 Unreliable Transport Protocol을 사용한다. 따라서 손실된 SIP 메시지들의 신뢰성을 보장하기 위하여 재전송 메커니즘을 제공한다. 하지만 이러한 재전송 메커니즘은 SIP 프록시 서버가 과부하 상황일 경우 신뢰성보다는 오버헤드가 증가되는 문제점을 가진다. 기존의 여러 SIP 과부하 제어 방법이 제안되었지만 네트워크 혼잡이 증가함에 따라 프록시 서버의 처리율이나 호 설정 시간의 지연 문제를 효율적으로 해결하지 못한다. 본 논문에서는 SIP 시그널링 네트워크에서 프록시 서버가 과부하 상황일 경우 낮은 호 설정 지연시간과 높은 처리율을 위해 우선순위 스케줄링 기반의 과부하 제어 알고리즘을 제안한다. 그리고 기존 과부하 제어에서 사용하는 알고리즘과 제안하는 알고리즘을 비교하여 보았다. 성능 평가 결과 부하에 따른 프록시 서버의 처리율과 호 설정 시간의 지연 측면에서 기존의 과부하 제어 알고리즘보다 향상됨을 보였다.

COVART 모델 기반의 함정 취약성 설계 및 평가 방법론 개발에 관한 연구

이장현(JangHyun Lee),김광식(KwangSik Kim) (사)한국CDE학회 2011 한국 CAD/CAM 학회 학술발표회 논문집 Vol.2011 No.1

It is important to assess and improve the warship survivability for the weapon threats which have an critical effect on warship. Warship Survivability is defined as the capability of a warship to avoid or withstand a man-made hostile environment. The survivability of the warship consists of three categories (susceptibility, vulnerability and recoverability). Firstly, the susceptibility is defined as the inability of a warship to avoid radars, guns, missiles and ETC. Secondly, the vulnerability is defined as the inability of a warship to withstand the man-made hostile environment. Finally, the recoverability is defined as the ability of a warship to recover the damaged components and systems. This paper has described the vulnerability assessment for the hypothetical system which is composed of critical components. Also, the procedure based on the CAVART model is suggested to calculate the vulnerable probability of the damaged warship.

The Comparison of Different 3D Graphic Programs for Making Orthotic Devices Using 3D Printing Technology

Limgyu Lee,Seungwoo Ahn,Kyeongho Jang,Hyoungjun Jeon,Yongseok Choi,Seungju Lee,Janghyun Baek,Seoyoon Heo 대한전자공학회 2020 대한전자공학회 학술대회 Vol.2020 No.8