재난재해에 대응 가능한 보급형 실내 임시주거시설의 계획에 관한 연구

Jaeseong Ju,Mijin Park 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.4

국내에서도 홍수, 지진, 산사태, 화재 등의 다양한 재난재해로 인하여 이재민이 발생하고 있으며, 이 중 대다수가 이재민 임시주거시설로 대피하고 있다. 그러나 이재민 임시주거시 설 내에서 개인공간을 확보할 수 있는 실내 임시주거시설의 배치와 성능에 관한 계획은 미 비하다. 이에 이재민 임시주거시설 내 거주환경을 개선하기 위하여, 국민안전처에서 지정 한 1인당 최소 수용면적 3.3㎡로 실내 임시주거시설의 모듈을 구축, 모듈의 배치계획을 진 행하였으며, 실내 임시주거시설의 형태, 재료, 성능에 대한 평가 방향을 제시하였다. Even in South Korea, disaster victims are suffering from various disasters such as floods, earthquakes, landslides, fires, and most of them have evacuated to temporary housing facilities for disaster victims. However, there are few plans for the placement and performance of indoor temporary housing facilities provided to secure private space in temporary housing facilities for disaster victims. In order to improve the living environment in the temporary housing facility of the victim, we constructed a module of minimum temporary accommodation area per person of 3.3 square meters, designated by the MPSS, and are proceeding with the module arrangement plan, Presented the evaluation direction of the form, material and performance of the indoor temporary housing facility.

재난재해에 대응 가능한 보급형 실내 임시주거시설의 계획에 관한 연구

Ju, Jaeseong,Park, Mijin 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.4

국내에서도 홍수, 지진, 산사태, 화재 등의 다양한 재난재해로 인하여 이재민이 발생하고 있으며, 이 중 대다수가 이재민 임시주거시설로 대피하고 있다. 그러나 이재민 임시주거시설 내에서 개인공간을 확보할 수 있는 실내 임시주거시설의 배치와 성능에 관한 계획은 미비하다. 이에 이재민 임시주거시설 내 거주환경을 개선하기 위하여, 국민안전처에서 지정한 1인당 최소 수용면적 $3.3m^2$로 실내 임시주거시설의 모듈을 구축, 모듈의 배치계획을 진행하였으며, 실내 임시주거시설의 형태, 재료, 성능에 대한 평가 방향을 제시하였다. Even in South Korea, disaster victims are suffering from various disasters such as floods, earthquakes, landslides, fires, and most of them have evacuated to temporary housing facilities for disaster victims. However, there are few plans for the placement and performance of indoor temporary housing facilities provided to secure private space in temporary housing facilities for disaster victims. In order to improve the living environment in the temporary housing facility of the victim, we constructed a module of minimum temporary accommodation area per person of 3.3 square meters, designated by the MPSS, and are proceeding with the module arrangement plan, Presented the evaluation direction of the form, material and performance of the indoor temporary housing facility.

박용 프로펠러 생산 정보 시스템 개발

박재성,김동수,전차수,박정환,주상윤 한국경영과학회 2003 한국경영과학회 학술대회논문집 Vol.- No.1(1)

Developed in this research is a production information system for marine propellers. The paper deals with surface modeling and tool path generation modules of the system. Since the input point data may have some errors, the data is examined using the 2nd divided difference. The point data is interpolated to a G2 chord-length spline surface with some end-conditions. The effects of the various end-conditions on the interpolated surface are discussed in the paper. The tool paths for blade, fillet, and boss of the propeller are generated. Some illustrative examples from an industry are presented.

박용프로펠러 생산정보시스템 개발

박재성(Jaeseong Park),김동수(Dong-Soo Kim),전차수(Cha-Soo Jun),박정환(Jung W. Park),주상윤(Sang-yoon Ju) 대한산업공학회 2003 대한산업공학회 춘계학술대회논문집 Vol.2003 No.5

Effect of plasma membrane monoamine transporter genetic variants on pharmacokinetics of metformin in humans

Seol Ju Moon,Jaeseong Oh,SeungHwan Lee,Yewon Choi,Kyung-Sang Yu,Jae-Yong Chung 대한임상약리학회 2018 Translational and Clinical Pharmacology Vol.26 No.2

Metformin, an oral hypoglycemic agent belonging to biguanide class, is widely used to treat type 2diabetes mellitus, and several drug transporters such as organic cation transporters (OCTs), multidrugand toxin extrusion transporter (MATE), and plasma membrane monoamine transporter(PMAT) are thought to affect its disposition. We evaluated the role of PMAT genetic variations onthe pharmacokinetic characteristics of metformin in a Korean population. In this retrospectivestudy, 91 healthy subjects from four different metformin pharmacokinetic studies were analyzed;in each study, the subjects were administered two oral doses of metformin at intervals of 12 hoursand dose-normalized pharmacokinetic parameters were compared between the subjects’ genotypes. Subjects who had more than one allele of c.883-144A>G single nucleotide polymorphism (SNP)in PMAT gene (rs3889348) showed increased renal clearance of metformin compared to wild-typesubjects (814.79 ± 391.73 vs. 619.90 ± 195.43 mL/min, p=0.003), whereas no differences in metforminexposure were observed between the PMAT variant subjects and wild-type subjects. Similarly,subjects with variant rs316019 SNP in OCT2 showed decreased renal clearance of metformin comparedto wild-type subjects (586.01 ± 160.54 vs. 699.13 ± 291.40 mL/min, p=0.048). Other SNPs inPMAT and MATE1/2-K genes did not significantly affect metformin pharmacokinetics. In conclusion,the genetic variation of c.883-144A>G SNP in PMAT significantly affects the renal clearance ofmetformin in healthy Korean male subjects.

재해 시 보급 가능한 실외 임시주거시설 디자인 계획안에 관한 연구

Minseok Kim,Jaeseong Ju,Taejun Yeom,Mijin Park 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.2

환경오염이 심각해지면서 자연재해가 빈번해지고 그 피해도 증가하고 있다. 또한 인구 과밀화로 사회적 재난도 빈번해지며 지역과 범위, 피해가 다양해서 예측이 어렵다. 재해가 다양해지고 피해규모도 커지면서 재해 시 이재민의 규모와 대피기간이 다양해졌다. 주거를 상실한 이재민에게 2차 피해로부터 보호받을 시설을 신속하게 제공해야 한다. 이에 조립식 주택을 지원하고 있지만 보급이 어렵다는 단점이 있다. 본 연구에서는 대피시설의 수용능력이 부족하거나 대피시설이 미비할 때 신속한 보급이 가능한 실외용 임시주거시설을 계획하는 것이 최종 목표이다. As environmental pollution becomes serious, natural disasters are frequent and damage is increasing. Also, due to population overcrowding, social disasters are frequent, and it is difficult to predict due to the variety of area, extent, and damage. As the disasters have diversified and the scale of the damage has increased, the scale of evacuees and the period of evacuation have diversified. Should be provide facilities that will be protected from second damages to victims who have lost their homes quickly. It supports a prefabricated house, but it is difficult to supply it. In this study, the ultimate goal is to plan an outdoor temporary housing facility that can supply quickly when the capacity of the evacuation facility is insufficient or the evacuation facility is insufficient.

재해 시 보급 가능한 실외 임시주거시설 디자인 계획안에 관한 연구

Kim, Minseok,Ju, Jaeseong,Yeom, Taejun,Park, Mijin 한국재난정보학회 2017 한국재난정보학회 논문집 Vol.13 No.2

환경오염이 심각해지면서 자연재해가 빈번해지고 그 피해도 증가하고 있다. 또한 인구 과밀화로 사회적 재난도 빈번해지며 지역과 범위, 피해가 다양해서 예측이 어렵다. 재해가 다양해지고 피해규모도 커지면서 재해 시 이재민의 규모와 대피기간이 다양해졌다. 주거를 상실한 이재민에게 2차 피해로부터 보호받을 시설을 신속하게 제공해야 한다. 이에 조립식 주택을 지원하고 있지만 보급이 어렵다는 단점이 있다. 본 연구에서는 대피시설의 수용능력이 부족하거나 대피시설이 미비할 때 신속한 보급이 가능한 실외용 임시주거시설을 계획하는 것이 최종 목표이다. As environmental pollution becomes serious, natural disasters are frequent and damage is increasing. Also, due to population overcrowding, social disasters are frequent, and it is difficult to predict due to the variety of area, extent, and damage. As the disasters have diversified and the scale of the damage has increased, the scale of evacuees and the period of evacuation have diversified. Should be provide facilities that will be protected from second damages to victims who have lost their homes quickly. It supports a prefabricated house, but it is difficult to supply it. In this study, the ultimate goal is to plan an outdoor temporary housing facility that can supply quickly when the capacity of the evacuation facility is insufficient or the evacuation facility is insufficient.

실내·외 임시주거시설의 성능 가이드라인 도출에 관한 연구

주재성,박지용,곽동화,박미진,Ju, Jaeseong,Park, Jiyong,Gwak, Donghwa,Park, Mijin 한국재난정보학회 2018 한국재난정보학회 논문집 Vol.14 No.3

Purpose: This study is designed to develop performance guidelines for temporary residential facilities inside and outside the building to improve the residential habit of the victims caused by a disaster. Method: Performance items were set up by analyzing the disaster response system and prior study for eliciting performance guidelines and conducting field surveys of temporary housing facilities and interviews of temporary residential facilities for eliciting relevant performance guidelines. Results: The performance of temporary housing facilities in and out of the country was largely classified as technical, environmental and social, and each presented performance guidelines. The derived performance guidelines were generally similar, although some were similar due to indoor/outdoor characteristics. Conclusion: The performance guidelines presented in this study to improve the residential habit of the victims are applied in practice, and continuous improvement through feedback of results is required. 연구목적: 본 연구는 재난재해로 인하여 발생한 이재민 거주성을 향상시키기 위한 실내 실 외 임시주거시설의 성능 가이드라인을 도출하는 것을 목적으로 한다. 연구방법: 재난재해 대응체계 및 선행연구를 분석하고, 국내 실정에 맞는 성능 가이드라인의 도출을 위하여 임시주거시설 현장조사와 임시주거시설 이용자 인터뷰를 진행하여 성능 항목을 설정하였다. 연구결과: 살내 외 임시주거시설의 성능은 크게 기술성, 환경성, 사회성으로 분류되었으며, 각각의 성능 가이드라인을 제시하였다. 도출된 성능 가이드라인은 실내/실외의 특성상 일부 유사하게 나타났으나 대체로 유사하였다. 결론: 본 연구에서 이재민 거주성 향상을 위하여 제시된 성능 가이드라인을 실질적으로 적용하여 개선을 진행하고, 결과의 피드백을 통한 지속적인 개선이 요구된다.

Pharmacokinetics of Second-Line Antituberculosis Drugs after Multiple Administrations in Healthy Volunteers

Park, Sang-In,Oh, Jaeseong,Jang, Kyungho,Yoon, Jangsoo,Moon, Seol Ju,Park, Jong Sun,Lee, Jae Ho,Song, Junghan,Jang, In-Jin,Yu, Kyung-Sang,Chung, Jae-Yong American Society for Microbiology 2015 Antimicrobial Agents and Chemotherapy Vol.59 No.8

<P>Therapeutic drug monitoring (TDM) of second-line antituberculosis drugs would allow for optimal individualized dosage adjustments and improve drug safety and therapeutic outcomes. To evaluate the pharmacokinetic (PK) characteristics of clinically relevant, multidrug treatment regimens and to improve the feasibility of TDM, we conducted an open-label, multiple-dosing study with 16 healthy subjects who were divided into two groups. Cycloserine (250 mg), <I>p</I>-aminosalicylic acid (PAS) (5.28 g), and prothionamide (250 mg) twice daily and pyrazinamide (1,500 mg) once daily were administered to both groups. Additionally, levofloxacin (750 mg) and streptomycin (1 g) once daily were administered to group 1 and moxifloxacin (400 mg) and kanamycin (1 g) once daily were administered to group 2. Blood samples for PK analysis were collected up to 24 h following the 5 days of drug administration. The PK parameters, including the maximum plasma concentration (<I>C</I><SUB>max</SUB>) and the area under the plasma concentration-time curve during a dosing interval at steady state (AUC<SUB>τ</SUB>), were evaluated. The correlations between the PK parameters and the concentrations at each time point were analyzed. The mean <I>C</I><SUB>max</SUB> and AUC<SUB>τ</SUB>, respectively, for each drug were as follows: cycloserine, 24.9 mg/liter and 242.3 mg · h/liter; PAS, 65.9 mg/liter and 326.5 mg · h/liter; prothionamide, 5.3 mg/liter and 22.1 mg · h/liter; levofloxacin, 6.6 mg/liter and 64.4 mg · h/liter; moxifloxacin, 4.7 mg/liter and 54.2 mg · h/liter; streptomycin, 42.0 mg/liter and 196.7 mg · h/liter; kanamycin, 34.5 mg/liter and 153.5 mg · h/liter. The results indicated that sampling at 1, 2.5, and 6 h postdosing is needed for TDM when all seven drugs are administered concomitantly. This study indicates that PK characteristics must be considered when prescribing optimal treatments for patients. (This study has been registered at ClinicalTrials.gov under registration no. NCT02128308.)</P>

Association between Alcohol Intake and Abdominal Obesity among the Korean Population

Mikyung Ryu,Heejin Kimm,Jaeseong Jo,Sun Ju Lee,Sun Ha Jee 한국역학회 2010 Epidemiology and Health Vol.32 No.-

OBJECTIVES: Although abdominal obesity has been reported to be highly related with alcohol intake, the results are still inconclusive. Therefore, this study was conducted to explore the association between alcohol and abdominal obesity among the Korean population. METHODS: This study included 8,603 participants (men: 5,195, women: 3,408) aged 30 to 87 who visited the health promotion centers in Seoul for routine health examinations from April, 2006 to June, 2007. Abdominal obesity was defined as WC ≥90 cm for men and ≥85 cm for women in accordance with the Korean Society for the Study of Obesity. For ever drinkers, total alcohol consumption in grams was classified into four groups (group 1, non-drinkers; group 2, 1-10 g of alcohol per day; group 3, 11-20 g of alcohol per day; and group 4, over 20 g of alcohol per day). RESULTS: The mean age of the study population was 45.4 yr old (men) and 45.3 yr (women). The average waist circumference was 85.3 cm in men and 75.3 cm in women. A high alcohol intake was associated with high waist circumference in both genders. In multivariate analysis, the group of men and women drinkers consuming >20 g in a day had a large waist circumference compared with men and women non-drinkers. CONCLUSION: This study showed that a high alcohol intake was related to high waist circumference. Such association remained independently even after adjustment for smoking, which is strongly related to abdominal obesity.