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( Jae Ho Lee ),( Da Eun Lee ),( Hye Min Choi ),( Ha Hyung Kim3 ),( Ho Kim ),( Jae Sam Hwang ),( Dong Gun Lee ),( Jae Il Kim ) 생화학분자생물학회(구 한국생화학분자생물학회) 2014 BMB Reports Vol.47 No.11
Defensins, which are small cationic molecules produced by organisms as part of their innate immune response, share a common structural scaffold that is stabilized by three disulfide bridges. Coprisin is a 43-amino acid defensin-like peptide from Copris tripartitus. Here, we report the intramolecular disulfide connectivity of cysteine-rich coprisin, and show that it is the same as in other insect defensins. The disulfide bond pairings of coprisin were determined by combining the enzymatic cleavage and mass analysis. We found that the loss of any single disulfide bond in coprisin eliminated all antibacterial, but not antifungal, activity. Circular dichroism (CD) analysis showed that two disulfide bonds, Cys20-Cys39 and Cys24- Cys41, stabilize coprisin’s α-helical region. Moreover, a BLAST search against UniProtKB database revealed that coprisin’s α-helical region is highly homologous to those of other insect defensins. [BMB Reports 2014; 47(11): 625-630]
Silica Gel-MoO₃觸媒에 의한 Methanol의 酸化反應
김재구,정국삼,홍윤명 연세대학교 산업기술연구소 1983 논문집 Vol.15 No.2
The vapor phase oxidation of methanol to formaldehyde over silica gel supported-MoO₃catalyst was studied at atmospheric pressure as a function of reaction temperature, feed rate and concentration. The silica gel supported-MoO₃catalyst was found very selective in formaldehyde formation but conversion was rather poor. The following rate equation was deduced assuming a steady state with two stage irreversible oxidation-reduction process. γ= ? The rate equation matched experimental data reasonably well and activation energies of the steps were calculated to be 8.345Kcal/g-mole and 7.074Kcal/g-mole respectively.
김영삼,권재술 한국교원대학교 과학교육연구소 1993 청람과학교육연구논총 Vol.3 No.1
도플러 공식을 유도하는데 있어 대부분의 교과서는 파동의 진행 과정을 직접 나타내지 못함으로써 고도의 상상력을 요구하고 있다. 그러한 과정 자체가 보여주는 이해의 난점 때문에 고등학교에서는 이에 대한 교육에 어려움을 느끼고 있다. 이러한 교육적 문제점들을 줄여 보기 위한 시도로 학생들이 이해하기 쉬운 위치-시간 그래프를 이용하였고, 기초적인 삼각법을 적용하여 도플러 공식을 좀 더 쉽고 간편하게 유도할 수 있는 방법을 알아 보았다. 이 방법은 운동을 그래프로 표현하는 능력만 있으면 이해가 가능하기 때문에 보다 더 구체적인 상황과 객관적인 과정을 통하여 도플러 공식을 유도할 수 있는 장점이 있다고 사료된다. In the derivation of doppler formula, most high school and Undergraduate level textbooks have been imployed qualitative procedures. Since the procedure heavily depends on students' imaginative power to figure out the transmission, propagation, and reception of sound waves, studens might have difficulty to derive the doppler formula. In this research, a graphical method of the doppler formula derivation was used in order to overcome the difficulty. Two axes, distance and time, coordinates were employed and the movement of the source or the receiver were graphed in the coordinates. The period of signal transmission and signasl reception were determined geometrically on the graph: In this paper, three different cases were analysed and derived doppler formula respectively; (1) when the source moves with stationary receiver, (2) when the receiver moves with stationary source, (33) when the source and receiver moves together. The researchers expect that the method introduced in this study would provide a new way of teaching doppler effect in high school as well as in undergraduate lavel.
표면가열양샹에 의한 슬래브 콘크리트의 저온기 강도조기발현에 관한 연구
김형래,이재삼,지남용 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2
The purpose of this study is to analyze several methods for accelerating concrete strength development at early ages. For this, the mix proportion of concrete. the kinds of chemical admixture and the curing temperature at early days were considered as the method for achieving 2/3 of design strength within 1.5~2.0 days after placing concrete. As the results. application of high strength concrete of W/C 34% was not able to acquire the required strength under the temperature condition below average 15℃. Although it's possible, the method would be too expensive. Consequently, high temperature curing method by surface planar heater at early days was considered. Only first 24 hours heating made possible the achieving of required strength.
김영삼,권재술 한국교원대학교 과학교육연구소 1996 청람과학교육연구논총 Vol.6 No.1
시공간 그래프는 고전약학의 운동학에서부터 많이 활용되어 왔다. 그것은 수식이 갖는 의미표현의 제약을 넘어서 그 의미를 좀더 구체적으로 시각화 할 수 있는 그래프의 특성때문일 것이다. 특수 상대성 이론의 운동학을 기술하는데도 이 그래프를 도입하여 고적역학적 그래프와 비교하여 그 특성을 먼저 이해한다면 보다 쉽게 특수 상대론적 운동학을 이해할 수 있을 것으로 생각한다. 따라서 본 연구는 상대론적 시공간 좌표계의 특성을 보다 근본적으로 이해할 수 있는 과정을 소개함으로써 특수 상대론적 시공간 개념에 대한 구체적인 이해와 이를 이용한 로렌츠 변환식의 유도에 연구의 목적을 두었다. The graphical method has been used widely in solving problems on classical kinematics because it has the advantage of visualiztion. The same advantage is expected in solving relativistic kinematics problems which are also closely related to motion. In this study, Lorentz transformation formula was derived using a spacetime graph only. In the derivation, the method of representing events in the two different coordinates and invariance of spacetime interval were used. Pure geometrical method was applied without using any algebraic method. If the students who are familiar with graphical representation of motion will understand this method more easily than the algebraic method which appear in most textbooks.