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Factors Associated with Attending the National Cancer Screening Program for Liver Cancer in Korea
Noh, Dai-Keun,Choi, Kui-Son,Jun, Jae-Kwan,Lee, Hoo-Yeon,Park, Eun-Cheol Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.2
Background and Aims: The National Cancer Screening Program (NCSP) for liver cancer was initiated in 2003 in Korea. The objective of this study was to evaluate the participation rate of the program and to provide preliminary information on its results based on data collected by the NCSP in 2009. Methods: The target population of the NCSP for liver cancer in 2009 was comprised of 373,590 adults aged ${\geq}40$ years at high risk for liver cancer. Participation rates and positivity rates were assessed in this population. Multivariate logistic regression analysis was performed to determine the factors associated with participation in the NCSP for liver cancer. Results: The overall participation rate was 37.9% and 1,126 participants were positive at screening. The highest participation rates were observed in women, those in their 60s, National Health Insurance beneficiaries, and individuals positive for hepatitis B surface antigen. Positivity rates for men, those in their 70s, Medical Aid Program recipients and individuals with liver cirrhosis were the highest in the respective categories of gender, age, health insurance type, and risk factor for liver cancer. Conclusions: The participation rates of the NCSP for liver cancer are still low, despite the fact that the program targets a high-risk group much smaller than the general population. Efforts to facilitate participation and to reduce disparities in liver cancer screening among Korean men and women are needed. These results provide essential data for evidence-based strategies for liver cancer control in Korea.
Function of Lysine-148 in dTDP-D-Glucose 4,6-dehydratase from Streptomyces antibioticus Tu99
( Jae Kyung Sohng ),( Hyung Rae Noh ),( Oh Hyoung Lee ),( Sung Jun Kim ),( Ji Man Han ),( Seung Kwan Nam ),( Jin Cheol Yoo ) 한국미생물 · 생명공학회 2002 Journal of microbiology and biotechnology Vol.12 No.2
dTDP-D-glucose 4,6-dehydratase (TDPDH) catalyzes the conversion of dTDP-D-glucose to dTDP-4-keto-6-deoxy-D-glucose, and requires NAD+ as a coenzyme for its catalytic activity. The dTDP-D-glucose 4,6-dehydratase from Streptomyces antibioticus Tu99 tightly binds NAD+ [19]. In order to determine the role of lysine-148 in the NAD+ binding, the lysine of the dTDP-D-glucose 4,6-dehydratase from Streptomyces antibioticus Tu99 was mutated to various amino acids by site-directed mutagenesis. The catalytic activity of the four mutated enzymes of TDPDH did not recover after addition of NAD+. However, the activity of K159A, the mutated enzyme of UDP-D-glucose 4-epimerase (UDPE), recovered after the addition of NAD+ [15]. Although dTDP-glucose 4,6-dehydratase, and UDP-galactose (glucose) 4-epimerase are members of the short-chain dehydrogenase/reductase SDR family and the lysine-148 of TDPDH was highly conserved as in UDPE (Lys-l59), the function of the lysine-148 of TDPDH was different from that of UDPE. The mutated enzymes showed that the lysine-l48 of the dTDP-D-glucose 4,6-dehydratase played no role in the NAD+ binding. Accordingly, it is suggested that the lysine-l48 of the dTDP-D-glucose 4,6-dehydratase is involved in the folding of TDPDH.
Dorsal Short-Segment Fixation for Unstable Thoracolumbar Junction Fractures
Kim, Kwan-Sik,Oh, Sung-Han,Huh, Ji-Soon,Noh, Jae-Sub,Chung, Bong-Sub The Korean Neurosurgical Society 2006 Journal of Korean neurosurgical society Vol.40 No.4
Objective : This study is to evaluate the efficacy of dorsal short-segment fixation in unstable thoracolumbar junction fractures. Methods : The cases of 20 patients who underwent dorsal short-segment fixation were reviewed retrospectively. Clinical outcomes were analysed using Sonntag's pain level, work status, and neurological scale according to the modified Frankel classification. Radiological outcomes were analysed using Mumford's anterior body compression[%], canal compromise ratio, and Cobb's kyphotic angle. Results : At the latest clinical follow-up [average=14.6 months]. there were 19 [95.0%] in group I and 1 patient [5.0%] in II in pain level. The postoperative work status were 17 [85.0%] in group I, 2 patients [10.0%] in II, and 1 patient [5.0%] in V. Surgery brought to improve the neurologic status. In success group [19 cases, 95%], the average canal compromise ratio was reduced from 0.57 [${\pm}0.07$] to 0.05 [${\pm}0.08$] [P<005], the average anterior body compression [%] was reduced from 41% [${\pm}17$] to 18% [${\pm}14$] [P<0.05], and the average preoperative kyphotic angle was $20.0^{\circ}$ [${\pm}9.0$], and corrected to $5.7^{\circ}$ [${\pm}7.1$] postoperatively, and progressed to $7.8^{\circ}$ [${\pm}6.2$] at the latest follow-up. There was a case of implantation failure in an elderly osteoporotic patient. Conclusion : Although there are limitations in the patient number and follow-up period, the present study favors dorsal short-segment fixation for selective cases in unstable thoracolumbar junction fractures.
Artificial Collision-Based Dynamic Slot Assignment for In-Band Control Networks
Jong-Kwan Lee,Kyu-Man Lee,Hong-Jun Noh,Jae-Sung Lim IEEE 2014 IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS Vol.13 No.11
<P>In this paper, we propose a novel dynamic slot-assignment scheme using artificial collisions called artificial collision-based dynamic slot assignment (AC-DSA) for multi-hop networks, which is based on the in-band control mechanism. In-band control-based networks have no exclusively reserved slots for newly arrived nodes; thus, the throughput can be improved compared with that of the out-of-band control-based networks. In in-band control based networks, a newly arrived node can use idle slots to transmit its control packet to request a slot assignment. However, if no idle slots are available, the node cannot transmit its control packet even though it has a higher priority than the existing nodes in the network, because a newly arrived node has to wait until idle slots are available in conventional schemes. To address this issue, AC-DSA uses the duration information of artificial packet collisions as a control message for slot assignment, which enables nodes with high priority to deprive a non-idle slot of nodes with low priority to guarantee quality of service requirements when no idle slots are available. We formulate an analytical model for the proposed slot-assignment scheme and compare it with the conventional one. Further, we demonstrate the feasibility and efficiency of the AC-DSA during high-traffic conditions considering the capture effect.</P>
Desmoplastic Fibroma of the Skull
Kim, Kwan-Sik,Noh, Jae-Sub,Chung, Bong-Sub,Shin, Mi-Kung The Korean Neurosurgical Society 2006 Journal of Korean neurosurgical society Vol.39 No.5
Desmoplastic fibromas are rare intraosseous bone tumors. They are benign but locally aggressive and frequently found in the long bones and mandible. We report radiographic and histopathologic finding of a case desmoplastic fibroma involving right temporal skull bone. A 53-year-old woman presented at our hospital complaining of continuous right side headaches for a year. Simple skull X-ray film showed $3{\times}2.5cm$ lytic lesion with mild sclerotic margin on right temporal area. A large craniectomy 1cm lateral to margin was fashioned. The resected mass showed encapsulated mass colored white gray. Histologic diagnosis was compatible with that of a the desmoplastic fibroma. There was no evidence of recurrence during the 15months of follow-up period.
임신 제 3삼분기에서 태아 대장 성장의 초음파 측정에 관한 연구: 전향적 종적 연구
노재홍 ( Jae Hong Noh ),서영훈 ( Young Hoon Suh ),홍준석 ( Joon Seok Hong ),박교훈 ( Kyo Hoon Park ),박중신 ( Joong Shin Park ),전종관 ( Jong Kwan Jun ),윤보현 ( Bo Hyun Yoon ),신희철 ( Hee Chul Syn ) 대한산부인과학회 2006 Obstetrics & Gynecology Science Vol.49 No.11
목적: 정상 단태임신 28주에서 40주까지 태아 횡행결장 외지름의 정상역을 확립하고자 한다. 연구 방법: 본 연구는 제 1 삼분기 이전에 처음 산전진찰을 받은 38명의 정상 단태 임산부를 대상으로 전향적 종적 연구를 시행하였다. 통상적 산전진찰 일정에 따라 임신 28주부터 임신 36주까지 매 2주마다, 그 이후 분만까지 매 1주마다 지속적으로 태아의 횡행결장 지름을 복부 초음파를 이용하여 측정하였다. 통계적 분석을 위하여 선형 회귀 분석을 시행하였다. 결과: 38명의 정상 임신부에게서 횡행결장 지름은 총 201개가 측정되었다. 임신 28주에서 40주까지 횡행결장 외지름을 평균, 95% 신뢰구간, 범위를 구하여 외지름의 정상역을 제시하였다. 38명의 각 임신부에서 측정된 대장 지름 중 무작위로 한 개의 값을 선택하여 선형 회귀 분석을 시행한 결과 임신 주수 (GA)와 횡행결장 지름 (TCD) (TCD=0.499 × GA - 0.5504 , R2=0.65; p<0.0001)은 직선적 성장 방정식을 나타내었다. 결론: 본 연구에서 임신 28주부터 40주까지 임신 주수에 따른 태아 횡행결장 외지름에 대한 정상역과 회귀 방정식을 제시하였다. 이러한 결과는 태아 횡행결장 외지름의 정상 성장에 관한 자료를 제공함과 동시에 태아 대장의 이상 여부를 발견하는데 매우 유용한 자료로 이용될 수 있을 것으로 사료된다. Objective: The purpose of this study was to establish a normal range for the outer diameter of the fetal transverse colon from 28 to 40 weeks` gestation. Methods: This prospective longitudinal study enrolled 38 consecutive women with uncomplicated singleton gestations during their first trimester of pregnancy. Ultrasound for serial measurements of the fetal transverse colon diameter were performed at intervals of 2 weeks from 28 weeks to 36 weeks and then weekly until delivery. Linear regression was used for statistical analysis. Results: A total of 201 transverse colon diameters were measured in all 38 fetuses. The normal range for the outer diameter of the transverse colon from 28 to 40 weeks` gestation was presented as mean, 95% confidence interval of the mean and range. A linear growth function was observed between gestational age (GA) and transverse colon diameter (TCD) (TCD=0.499×GA - 0.5504, r2=0.65; p<0.0001). Conclusion: We have presented a table of normal range and a regression formula for outer diameter of the fetal transverse colon from 28 to 40 weeks` gestation. These data may serve as reference values in the detection of abnormalities of the fetal colon.