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朴炳哲,文宰奎,朴榮吉,金杏順,安年衡,金度勳,金正勳,安榮根,李相根,鮮于演 圓光大學校 1990 論文集 Vol.24 No.2
食用油脂는 健康維持에 必須的인 營養素이다. 그러나 食用油脂는 脂肪을 構成하는 脂肪酸의 種類와 攝取하는 量에 따라 健康을 保衛하는 必須的인 食品의 成分이 되기도 하고 有害한 影響을 끼칠 수도 있어서 脂質代謝와 關連된 疾病 뿐만아니라 老化를 促進하고, 乳房癌, 大腸癌等의 癌發生과도 關連된 것으로 밝혀져 있다. 本 硏究는 우리生活環境에서 食用으로 接할 수 있는 10種의 油脂에 對한 免疫生物學的인 活性에서 究明한 結果 對照群인 참기름食餌群에 比해 올리브유食用群은 全般的으로 體液性 및 細胞性免疫을 有意性있게 增加시켰으나, 大食細胞의 活性과 末梢循環白血球數는 有意性없는 減少를 보였고, 動物性 油脂인 牛脂食餌群과 植物性 油脂인 옥수수기름食餌群, 들기름食餌群, 米糠油食餌群, 大豆油食餌群, 菜種油食餌群 및 고추씨기름食餌群에서는 全般的으로 體液性 및 細胞性免疫, 大食細胞의 活性 및 末梢循環白血球數를 有意性있게 減少시켰다. This study was performed to investigate the effects of edible oils and fats on the immunobiological responses in ICR male mice. Ten groups of experimental diets, such as sesame oil diet, beef tallow diet, lard oil diet, olive oil diet, corn oil diet, perilla oil diet, rice polishing oil diet, soybeen oil diet, rape seed oil diet, and red pepper seed oil diet were fed adlibitum to the ICR male mice for 27 days. The results of this study were summarized as followings. 1. Both humoral and cellular immune responses, phagocyte activity, and number of leukocytes in sesame oil group were increased. However, the increasing rate of body weight and the weight retios of spleen and thymus to body were generally decreased. 2. Hemagglutination titer(HA) and rosette forming cell(RFC) of the beef tallow group and the lard group were significantly lower than the sesame oil group(P<0.01), but the lard group significantly increased Arthus reaction and delayed type hypersensitivity(DTH)(P<0.01). 3. Arthus reaction, DTH, and RFC of the olive oil group were significantly higher than the sesame oil group(P<0.01). 4. DTH of the corn oil group was significantly higher than the sesame oil group(P<0.01) whereas phagochyte activity was significantly lower(P<0.01). But no statistically significant differences were found between the two groups in the humoral immune response. 5. HA, PFC, DTH, RFC, phagocyte activity, and number of leukocytes of the perilla oil group and the rice polishing oil group were significantly lower than the sesame oil group(P<0.01). 6. Both humoral and cellular immune responses, phagocyte activity, and number of leukocytes of the soybeen oil group, the rape seed oil group, and the red pepper oil group were significantly lower than the sesame oil group(P<0.01).
Synergistic effects of longitudinal amyloid and vascular changes on lobar microbleeds
Kim, Yeo Jin,Kim, Hee Jin,Park, Jae-Hyun,Kim, Seonwoo,Woo, Sook-Young,Kwak, Ki-Chang,Lee, Jong Min,Jung, Na-Yeon,Kim, Jae Seung,Choe, Yearn Seong,Lee, Kyung-Han,Moon, Seung Hwan,Lee, Jae-Hong,Kim, Yun Ovid Technologies (Wolters Kluwer) - American Acad 2016 Neurology Vol.87 No.15
<P>Conclusions: Our findings suggest that amyloid-related pathology and hCSVD have synergistic effects on the progression of lobar microbleeds, providing new clinical insight into the interaction between amyloid burden and hCSVD on CMB progression and cognitive decline with implications for developing effective prevention strategies.</P>
Clinical effect of white matter network disruption related to amyloid and small vessel disease
Kim, Hee Jin,Im, Kiho,Kwon, Hunki,Lee, Jong-Min,Kim, Changsoo,Kim, Yeo Jin,Jung, Na-Yeon,Cho, Hanna,Ye, Byoung Seok,Noh, Young,Kim, Geon Ha,Ko, En-Da,Kim, Jae Seung,Choe, Yearn Seong,Lee, Kyung Han,Ki Ovid Technologies (Wolters Kluwer) - American Acad 2015 Neurology Vol.85 No.1
<P>We tested our hypothesis that the white matter network might mediate the effect of amyloid and small vessel disease (SVD) on cortical thickness and/or cognition.</P>
장재훈,최병연,김헌주,한용표,최중언,김영수,정상섭,이규창 대한신경외과학회 1982 Journal of Korean neurosurgical society Vol.11 No.4
Sixty five intracranial abscesses were experienced from December, 1970 to August, 1981, of which fifty seven cases were operated. The clinical analysis and surgical experiences were summarized as follows. 1) The patients consisted of 45 male and 12 female and 31 patients(54.4%) were under 20 years of age. 2) Of the 57 patients, 45 patients(79%) had a demonstrable infectious source leading to the intracranial infection. There were 15 patients with ear infection and 13 patients with trauma. 3) Staphylococcus and streptococcus were the most common pathogens in this study. 4) Common symptoms of the patients were headache and fever, which were followed by mental disturbance and focal neurologic disturbance. 5) Brain CT scan offered accurate, non-invasive, rapid and easily repeatable means of diagnosis and following of lesions. After contrast infusion, ring enhancement had mostly thin and regular wall (88%). 6) The best operative methods of the brain abscess were aspiration and resection, or drainage and resection. The deep seated brain abscess, subdural abscess and epidural abscess could be treated using only drainage method with good results.