야생 돌복숭아 씨와 과육의 아미노산 및 지방산 조성에 관한 연구

김한수,Kim, Han-Soo 한국생명과학회 2007 생명과학회지 Vol.17 No.1

우리나라 전역에서 자생하는 야생 돌복숭아(Prunus persica Batsch var, davidiana Max.)의 씨와 과육 중의 각종 생리활성 물질을 규명하여 바이오헬스 기능성 소재 등의 자원으로서 이용 가능성을 검토하기 위한 자료로, 돌복숭아 씨와 과육 중의 일반성분, 구성 총 아미노산, 유리 아미노산 및 지질 구성 지방산 조성을 분석한 결과는 다음과 같다. 돌복숭아 씨 및 과육 중의 일반성분 함량은 탄수화물이 63.92% 와 75.11%로 대부분을 차지하였으며, 조단백질 27.85%, 12.77%, 수분 3.61%, 4.69%, 조지 방이 1.21%, 4.80% 그리고 조회분이 3.41%와 2.63% 함유되어 있는 것으로 나타났다. 돌복숭아 씨 중의 구성 총 아미노산의 함량은 3,444.35 mg%로 이 중 aspartic acid가 681.10 mg%, glutamic acid 495.48 mg%, alanine 283.66 mg%, serine 251.36 mg%, proline 229.80 mg%, lysine 192.31 mg% 및 leucine이 191.34 mg%의 순으로 조성되어 있었으며, 특히 aspartic acid 및 glutamic acid가 대부분을 차지하였다. 돌복숭아 과육의 단백질 구성 아미노산 조성의 총 함량은 1,064.02 mg%로, aspartic acid 250.15 mg%, glutamic acid는 129.63 mg%로 과육의 주요 총 아미노산이었고 lysine, proline, leucine, alanine, serine 등의 순으로 함유되어 있었다. 돌복숭아 씨 중 유리 아미노산 조성의 총 함량은 6,215.34 mg%로, 이 중 glutamic acid가 827.25 mg%로 가장 많았으며, threonine, valine, $\beta-aminobutyric$ acid 등의 순으로 함유되어 있었다. 과육 중의 유리 아미노산 조성의 총 함량은 683.82 mg%로, glutamic acid(339.49 mg%)가 대부분 이었으며, serine, proline, alanine, $\gamma-amino-n-butyric$ acid의 순으로 함유되어 있었다. 지질 구성 지방산 조성은 포화지방산이 12.49%, 단불포화지방산 13.11% 및 다불포화지방산이 74.36%의 함유비율을 보였으며, 필수지방산인 n-6계 linoleic acid$(C_{18:2})$와 n-3계 linolenic acid$(C_{18:3})$가 대부분을 차지하였다. 야생 돌복숭아 과육 중의 지방산 조성은 포화지방산이 16.74%, 단불포화지방산 17.51% 및 다불포화지방산이 65.73%의 함유 비율을 보였는데, 이 중 다불포화지방산인 n-6계 linoleic acid$(C_{18:2})$와 n-3계 linolenic acid$(C_{18:3})$가 지질 구성 총 지방산의 대부분을 차지하는 함유 비율을 나타내었다. Amino acid and fatty acid compositions of the physiological activity substance in the seed and pulpy substance of feral peach (Prunus persica Batsch var. davidiana Max.) were analyzed for the use as an biohealth functional processed products. The proximate compositions in the vacuum freeze dried seed and pulpy substance of feral peach were carbohydrate 63.92% and 75.11%, crude protein 27.85% and 12.77%, moisture 3.61% and 4.69%, crude fat 1.21% and 4.80%, crude ash 3.41% and 2.63%, respectively. Total amino acid contents in the protein of feral peach seed were 3,444.35 mg%, and the major amino acids were aspartic acid(681.10 mg%), glutamic acid(495.48 mg%), alanine(283.66 mg%), serine(251.36 mg%), proline(229.80 mg%), lysine(192.31 mg%) and leucine(191.34 mg%), respectively. Total amino acid contents in the protein of feral peach pulpy substance were 1,064.02 mg%, and the major amino acids followed aspartic acid(250.15 mg%), glutamic acid(129. 63 mg%), lysine, proline, leucine, alanine and serine, in a decreasing order. The richest total amino acid content contained in feral peach seed and pulpy substance was aspartic acid, followed by glutamic acid. The amount of free amino acids of feral peach seed were 6,215.34 ms%, and the major free amino acids were glutamic acid(827.25 mg%), threonine, valine and $\beta-aminobutyric$ acid, respectively. Free amino acid contents of pulpy substance were 683.82 mg%, and the major free amino acids were glutamic acid(339.49 mg%), serine proline, alanine and $\gamma-amino-n-butyric$ acid. Especially, in the case of glutamic acid, it was highest. The compositions of major total fatty acid in the lipid feral peach (Prunus persica Batsch var. davidiana Max.) seed and pulpy sabstance were linoleic acid($C_{18:2}$, n-6) and linolenic acid($C_{18:3}$, n-3), particularly.

족부 및 족관절의 악성 종양

김한수,오주한,황창주,이한구,이상훈,Kim, Han-Soo,Oh, Joo-Han,Hwang, Chang-Joo,Lee, Han-Koo,Lee, Sang-Hoon 대한족부족관절학회 2001 대한족부족관절학회지 Vol.5 No.1

Purpose: We analyzed 35 patients of malignant tumors of the foot and ankle to evaluate clinical manifestation. result of treatment and prognosis. Materials and Methods: Thirty five patients who were histologically confirmed for malignant tumors of the foot and ankle from September 1984 to May 1999 were investigated. Results: There were 16 males and 19 females. with an average age 38.3 years. Ten tumors were originated from bone and 25 from soft tissue; osteosarcoma (8) was the most common bone tumor and synovial sarcoma (8) and malignant melanoma (6) were common in soft tissue tumors. Surgical procedures included; marginal resection (2), limb salvage procedure after wide resection (5) for bone tumors, and amputation (12), wide resection (4), marginal resection (5) for soft tissue tumors. In some cases, perioperative chemotherapy and radiotherapy were given. There were 2 local recurrences and 11 metastases; 5 metastases were found at the time of initial diagnosis. Average follow-up was 3.5 years. Conclusion: We conclude that suspicion and early diagnosis are important in malignant tumors of the foot and ankle, and the resection margin must be obtained more thoroughly during surgery with perioperative adjuvant therapy, if necessary.

현장 계측을 이용한 기둥축소 예측 모델의 오차 원인 분석

김한수,신승학,Kim, Han-Soo,Shin, Seung-Hak 대한건축학회 2012 대한건축학회논문집 Vol.28 No.6

This paper suggests how to identify the sources of the error in the column shortening analysis by using the field measurement. The causes of the error between structural analysis and field measurement can be divided into the loads and the column properties. These two error sources are acting simultaneously and make it difficult to identify the causes of the error. The method for identifying error sources by using the strain of upper and lower columns having equal section and material properties has been developed to increase the accuracy of the column shortening prediction. In order to verify efficiency of the proposed method, several numerical analysis having assumed errors were carried out. The results of the numerical analysis showed that the error sources could be identified in all cases. The proposed method can be used to investigate the errors between the prediction and the measurement and to enhance the accuracy of the prediction.

집합건물 회계처리기준의 개선방안에 관한 연구

김한수(Kim, Han-Soo) 한국회계정보학회 2021 재무와회계정보저널 Vol.21 No.4

[연구목적]다수의 구분소유자가 존재하는 집합건물에서 관리비를 둘러싼 분쟁이 끊이지 않아, 법무부는 2021년 2월 집합건물법 시행령 개정하였다. 이에 따라 일정 요건을 충족하는 집합건물 관리인은 복식부기회계와 발생주의회계에 따라 재무제표를 작성해야 하고, 감사인의 회계감사를 받아야 한다. 2021년 7월 법무부는 집합건물 회계처리기준을 제정하였는데, 본 연구는 동 기준을 분석해 개선방안을 제시하는 데 목적이 있다. [연구방법]연구목적을 달성하기 위해 구분소유의 공통점이 있는 집합건물과 공동주택 관련 법규와 회계처리기준을 비교․분석하였고, 관리비의 결정 주체, 주된 정보이용자와 정보이용자에게 유용한 정보를 검토하였다. [연구결과]집합건물 재무제표이용자에게 유용한 정보를 제공하기 위해 집합건물 회계처리기준의 개선방안을 제시하면 다음과 같다. 첫째, 회계처리기준에 구분소유자와 점유자를 이해관계자로 명확하게 기술해야 한다. 둘째, 공동주택 회계처리기준에서 제시한 일반원칙을 기준에 포함해야 한다. 셋째, 집합건물의 회계정보에 대한 비교가능성을 높이기 위해 회계연도를 획일적으로 규정하고, 집합건물정보시스템을 구축해 집합건물 재무제표를 비교할 수 있도록 해야 한다. 넷째, 집합건물 관리에서 발생할 수 있는 부정을 적시에 예방․적발할 수 있도록 내부통제와 관련한 통제절차를 기준에 포함해야 한다. 다섯째, 정보이용자에게 유용한 정보인 주요 보험 가입, 주요 적립금 명세, 미납관리비 연체 금액을 주석으로 기재하도록 해야 한다. 여섯째, 집합건물 특수성을 고려한 회계감사기준을 제정해야 한다. [연구의 시사점]본 연구는 정보이용자에게 더 유용한 회계정보를 제공할 수 있는 집합건물 회계처리기준의 개선방안을 제시했다는 공헌이 있다. [Purpose]Disputes over management costs in the condominium buildings have continued. Therefore, the Ministry of Justice revised the Enforcement Decree of the Act on Ownership And Management of Condominium Buildings in February 2021. Accordingly, managers of condominium buildings who meet certain requirements must prepare financial statements according to double-entry accounting and accrual accounting and undergo external audits. This study aims to analyze the standards and suggest improvement plans. [Methodology]I compared and analyzed the laws and accounting standards related to condominium buildings and multi-family housing that have a common property of division and ownership, and reviewed information suitable for the decision maker of management costs, main information users. [Findings]The results of this study are as follows. First, it is necessary to clearly describe the sectional owners and occupants as stakeholders in the accounting standards. Second, the general principles presented in the multi-family housing accounting standards should be included in the standards. Third, to increase the comparability of the accounting information of the condominium building, the fiscal year should be uniformly defined, and the condominium building information system should be established so that the financial statements of the condominium building can be compared. Fourth, control procedures related to internal control should be included in the standards to prevent and detect irregularities that may occur in condominium building management in a timely manner. Fifth, information users should be instructed to write in the footnotes relevant information such as major insurance subscriptions, major reserve details, and overdue amount of unpaid administrative expenses. Sixth, accounting audit standards should be established in consideration of the specificity of the condominium building. [Implications]This study has a contribution in that it suggests an improvement plan for the collective building accounting standards that can provide information users with more relevant accounting information.

Dy₂O₃-TiO₂ 산화물의 소결성 및 소결체 특성에 관한 연구

김한수,정창용,김시형,이병호,이영우,손동성,이상현,Kim, Han-Soo,Joung, Chang-Yong,Kim, Si-Hyung,Lee, Byoung-Ho,Lee, Young-Woo,Sohn, Dong-Seong,Lee, Sang-Hyun 한국세라믹학회 2002 한국세라믹학회지 Vol.39 No.11

산화물 제어봉 물질로서 $Dy_xTi_yO_z$ 소결체를 powder process에 의해 제조하였다. $Dy_2O_3+TiO_2$ 혼합분말의 소결성과 고용체의 상을 TMA와 XRD로써 각각 분석하였으며, 소결체의 비열과 열확산계수를 측정하여 열전도도를 구하였다. $Dy_xTi_yO_z$에서 Dy의 함량에 따라 소결성과 밀도가 변하였고 $3\;g\;Dy/cm^3\;Dy_xTi_yO_z$의 경우 $1580{\circ}C$의 소결온도에서 용융이 일어났다. $4.00\;g\;Dy/cm^3$ 소결체에는 $Dy_2TiO_5+Dy_2Ti_2O_7$의 두 상이 존재하며 $4.54\;g\;Dy/cm^3$의 경우 $Dy_2TiO_5$의 단일 상만이 존재하는 결과를 보였다. $Dy_xTi_yO_z$의 열전도도는 $25~600{\circ}C$ 범위에서 온도에 따라 큰 변화가 없으며 $1600{\circ}C$ 소결체가 1.69∼1.78 W/mK, 1550$^{\circ}C$ 소결체의 경우에는 1.49~1.55 W/mK이었다. .$Dy_xTi_yO_z$ pellets were fabricated as a reactor control material by the powder process. Sinterability of $Dy_2O_3+TiO_2$ mixtures and phases of solid solutions were analyzed by using TMA and XRD, respectively. The thermal conductivity of .$Dy_xTi_yO_z$ pellet was determined from the measurement data of the specific heat and the thermal diffusivity of the pellet. The sinterability and the sintered density varied as a function of Dy content in $Dy_xTi_yO_z$. The pellet of $3\;g\;Dy/cm^3\;Dy_xTi_yO_z$ melted in the sintering temperature of $1580{\circ}C$. There were two phases of $Dy_2TiO_5+Dy_2Ti_2O_7$ and a single phase of $Dy_2TiO_5$ for the pellet that has the Dy content of .$4.00\;g\;Dy/cm^3$ and .$4.54\;g\;Dy/cm^3$, respectively. The thermal conductivity of $Dy_xTi_yO_z$ was nearly constant in the temperature range of $25~600{\circ}$. It was 1.69~1.78 W/mK for the pellet sintered in .$1600{\circ}$ and 1.49~1.55 W/mK for the pellet sintered in $1550{\circ}$.

야생 돌복숭아(Prunus persica Batsch var. davidiana Max.) 추출액이 선천성 고혈압 흰쥐의 지질성분 및 혈압 저하에 미치는 영향

김한수,Kim, Han-Soo 한국생명과학회 2006 생명과학회지 Vol.16 No.7

야생 돌복숭아(Prunus persica Batsch var. davidiana Max.)의 생리활성 추출물질이 선천성 고혈압 흰쥐(SHR)의 지질대사 이상 및 고혈압 예방과 개선효과 등에 생리생화학적 효능이 있을 것으로 추정되어 Wistar 계 수컷 SHR을 사용하여, 기본식이와 물만을 급여한 대조군인 Control군과 SHR에 돌복숭아 5.0g% 추출액을 급여한 군(5g% Ex.군) 및 SHR에 돌복숭아 10.0g% 추출액을 섭취시킨 10g% Ex.군을 33일간 실험 사육하여 혈청 지질성분 및 혈압 저하 효과를 생리적 측면에서 검토하기 위하여 본 실험을 수행하였다. 혈청 중의 총 콜레스테롤 농도, 중성지방, LDL-콜레스테롤, 유리 콜레스테롤 및 동맥경화지수 등에서 돌복숭아 생리활성물질 5.0g%, 10.0g% 추출액을 섭취시킴으로서 유의적인 농도 등의 감소 효과를 보였으며, HDL-콜레스테롤 농도 및 총 콜레스테롤에 대한 HDL-콜레스테롤 비는 상승되는 것으로 나타났다. 한편, 간장 및 뇌 중의 총 콜레스테롤, 중성지방 농도는 돌복숭아 5.0g%, 10.0g% 추출액을 섭취시킨 군에서 감소되는 것으로 나타났다. 반면, 혈청 apolipoprotein(Apo) A-I, Apo A-II 농도 등은 돌복숭아 5.0g%, 10.0g% 추출액을 섭취시킨 군에서 유의적으로 증가되는 것으로 나타났다. 또한 Apo C-II, Apo C-III, Apo E 및 Apo A-I에 대한 Apo B의 농도 비는 감소되었으며, 혈압의 변화는 SHR에 돌복숭아 5.0g% 및 10.0g% 추출액을 섭취시킴으로서 혈압이 저하됨을 관찰할 수가 있었다. 돌복숭아 5.0g% 농도(5g% Ex.군)와 10.0g% 농도(10g% Ex.군)의 추출액 섭취에 따른 두 군간에 각종 지질성분과 apolipoprotein 분획 농도 및 혈압 변화의 비교는 유의적인 차이는 없었다 따라서 야생 돌복숭아 중의 생리활성물질 추출액 섭취가 선천성 고혈압 흰쥐에 대한 혈청 지질개선 및 심장순환기계 질환, 고혈압의 예방과 치료개선에 효과가 있을 것으로 생각된다. The purpose of this study was to observe the effects of the feeding physiological activity substance in feral peach(Prunus Persica Batsch var. davidiana Max.) extract intake on the improvement of the lipid compositions, apolipoprotein and blood pressure level in spontaneously hypertensive rats(SHR, Wistar strain, male) fed the experimental diets for 33 days. Concentrations of total cholesterol, triglyceride(TG), LDL-cholesterol, free cholesterol and atherosclerotic index in serum were significantly lower in the feral peach extract intake groups[groups 5g% Ex.(basal diet+feral peach 5.0g% extract), 10g% Ex.(basal diet+feral peach 10.0g% extract)] than those in the group Control(basal diet+water). In the ratio of HDL-cholesterol concentration to total cholesterol and HDL-cholesterol concentration, feral peach 5.0g%, 10.0g% extract intake groups(group 5g% Ex. and 10g% Ex.) were higher percentage than in the group Control. However, concentrations of total cholesterol and TC in liver and brain were significantly lower in the groups 5g% Ex. and 10g% Ex. than those in the group Control. But the concentrations of apolipoprotein (Apo) A-I and Apo A-II in serum were significantly higher in the feral peach 5.0g% and 10.0g% extract intake groups(5g% Ex. and 10g% Ex.) than in the control group. However, concentrations of Apo C-II, Apo C-III, Apo E and ratio of Apo B to Apo A-I in serum were fairly reduced in the groups 5g% Ex. and 10g% Ex. than in the control group. The levels of systolic and diastolic blood pressure were significantly lower in feral peach 5g% Ex. and 10g% Ex. groups than control group. However, no significance was found in the effect of among the groups(groups 5g% Ex. and 10g% Ex.). From these results, physiological activity substance in feral peach(Prunus persica Batsch var. davidiana Max.) extracts were effective on the improvement of the lipid compositions and cardiovascular heart disease, hypertension in spontaneously hypertensive rats. And particularly, feral peach extracts were more effective as a therapeutic regimen for the control of blood pressure in hypertension.

PIM-DM 멀티캐스트에서 그룹 가입 지연시간에 대한 성능 모의 실험

김한수,장주욱,Kim, Han-Soo,Jang, Ju-Wook 한국정보처리학회 2003 정보처리학회논문지 C : 정보통신,정보보안 Vol.10 No.2

PIM-DM을 이용하여 멀티캐스트를 하였을 때 그룹에 가입하기 위해서 대기하는 시간이 특정한 시간 영역에서 크게 증가하는 문제점이 있음을 확인하였다. 이는 그룹에서 탈퇴하기 위한 리브 프룬 메시지와 플러딩에 대한 응답으로 발생하는 플러딩 프룬 메시지를 라우터가 구분하지 못하는 것에서 기인한다. 본 논문에서는 이러한 문제점의 원인을 분석하고, 이에 대한 해결방법을 제시하였다. 또한, 이를 이용하여 그룹 가입 지연 시간이 평균 37.4% 감소됨을 네트워크 시뮬레이션을 통해서 확인하였다. One of the remarkable problems in PIM-DM (Protocol Independent Multicast - Dense Mode) is the join latency time, increasing for specific periods. The reason of this problem is proved to the confusion of flooding prune message and leave prune message. We propose a new solution to this problem, reducing the average join latency by 37.4%, and prove the proposed solution by network simulation.

몰로키아 분말을 첨가한 밀·보리 혼합 식빵의 제조 및 생리활성 평가

김한수,김영호,김애정,Kim, Han soo,Kim, Young Ho,Kim, Ae Jung 한국식품영양학회 2015 韓國食品營養學會誌 Vol.28 No.4

This study was performed to produce WBM (wheat and barley mixture) bread containing molokhia powder with quality characteristics and antioxidant activities. Analysis of the chromaticity of WBM prepared with molokhia powder showed that; the lightness and redness were decreased, but yellowness was increased. In mechanical properties, hardness, gumminess, and chewiness were significantly increased as the amount of molokhia powder was increased. However, cohesiveness was significantly decreased. In sensory evaluation, WBM bread containing 1.5% of molokhia powder (MB1.5) showed an overall high preference level. The total polyphenol content of molokhia powder EtOH extract and MB1.5 were 29.19 and 58.18 mg TAE/g, respectively. The total flavonoid contents of molokhia powder EtOH extract and MB1.5 were 20.62 mg and 33.25 mg RE/g, respectively. The radical scavenging ability ($IC_{50}$) of DPPH ($IC_{50}$) for molokhia powder EtOH extract and MB1.5 was 31.04 and $58.18{\mu}g/mL$, respectively while that of ABTS was 33.25 and $54.15{\mu}g/mL$, respectively. The ${\alpha}-glucosidase$ inhibitory effects of molokhia powder EtOH extract and MB1.5 were 494.88 and $814.88{\mu}g/mL$, respectively. MB bread containing 1.5% molokhia powder showed antioxidative effects and ${\alpha}-glucosidase$ inhibitory activity, meaning that not only molokhia but also MB1.5 bread has the potential to prevent chronic degenerative diseases such as diabetes.

가정운동 훈련프로그램이 노인의 균형증진에 미치는 영향

김한수,구봉오,김상수,Kim, Han-Soo,Goo, Bong-Oh,Kim, Sang-Soo 대한물리치료과학회 2002 대한물리치료과학회지 Vol.9 No.1

The purpose of this study was to investigate the effects of home exercise program on the improvement of balance in the elderly. Subjects were twenty members living in Daegu (10 males, 10 females), between 65 and 81 years of age. The subjects for the experimental group were participated in the home exercise program for 8 weeks, between April 2001 and June 2001. The results of this study were as follows: After the exercise program, balance ability by CTSIB in the experiment group improved with no statistical significance. On the other hand, balance ability by OLST was significantly improved in the condition with open eyes than dosed eyes. Balance ability by OLSTR was improved 37.2% (p<0.001) on the hard surface with open eyes and improved 41.1% (p<0.01) on the soft surface with open eyes. Balance ability by OLSTL improved 37.1% (p<0.001) on the hard surface with open eyes and improved 72.5% (p<0.001) on the soft surface with open eyes. Balance ability by BBT also improved 1.7% (p<0.05).

피부화상에 의한 피부 및 간의 조직학적 변화에 관한 연구

김한수,김상수,김용권,Kim, Han-Soo,Kim, Sang-Soo,Kim, Yong-Kwon 대한물리치료과학회 2001 대한물리치료과학회지 Vol.8 No.1

In order to investigate a pathogenesis of liver damage induced by skin burn, thermal injury was induced by scald burn on entirely dorsal surface in rats (total body surface area 30%) except for inhalated injury. At 5 and 24 h after scald bum, biochemical assay and morphological changes in skin tissue, serum and liver tissue were examined. The effects of bum injury on the levels of glutathione, lipid peroxide and on the activities of oxygen free radical generating and scavenging enzymes have been determined in association with observing of histologic and ultrastructural changes, measuring the protein concentration in plasma, and counting the number of intravascular polymorphonuclear leukocytes. The activity of xanthine oxidase, an enzyme of oxygen free radical generating system. was elevated (p<0.01) in serum, but not in skin and in liver tissue. Futhermore, thermal injury decreased not only the protein concentration in plasma but also the number of leukocytes, that indicates induction of edema formation with protein exudation and inflammation by neutrophil infiltration into the internal organs. These data suggest that acute dermal scald burn injury leads to liver damage, that is related to elevation of xanthine oxidase activity in serum. Xanthine oxidase may be a key role in the pathogenesis of liver damage induced by skin burn.