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      • KCI등재

        Isoflavone Composition, Total Polyphenolic Content, and Antioxidant Activity in Soybeans of Different Origin

        Vesna Tepavčević,Milica Atanackovic,Jegor Miladinovic,Djordje Malencˇic,Jovan Popovic,Jelena Cvejic 한국식품영양과학회 2010 Journal of medicinal food Vol.13 No.3

        Twenty soybean cultivars, originating from the United States, Russia, Serbia, and China, were analyzed for their isoflavone composition, total polyphenolic content, and antioxidant activity. Isoflavones were extracted by aqueous methanol (80%) and analyzed by high-performance liquid chromatography/diode array detection. Precision and linearity of the applied method were within the standard limits of validation. The highest and the lowest total isoflavone contents were 4.59 and 1.45mg/g of dried soybean weight, respectively. A significant difference (P<.05) was found in isoflavone concentration among the different cultivars, but it was observed that origin is not a significant factor that could influence isoflavone content in soybeans. Total polyphenolic content varied between 2.13 and 3.45mg of gallic acid equivalents/g of dried soybean weight. The free radical scavenging activity of soybean extracts assayed by 2,2-diphenyl-1-picrylhydrazyl in terms of 50% inhibitory concentration (IC50) ranged from 1.40 to 3.35mg/mL. Negative correlation between total polyphenolic content and IC50 was observed, but there was no correlation between total isoflavone content and IC50. On the basis of this study, soybean cultivars with larger potency for biological activity could be recognized.

      • KCI등재

        Biochemical Properties of the Fresh and Frozen Black Currants and Juices

        Boban Djordjevic,Katarina S ˇ avikin,Gordana Zdunic,Teodora Jankovic,Todor Vulic,Dejan Pljevljakusˇic,Cedo Oparnica 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.1

        Thirteen black currant varieties (Ribes nigrum L.) cultured in Serbia were characterized for their pomological properties and chemical composition (total phenolics, total anthocyanins, anthocyanin aglycones, sugars, and vitamin C). The average amount of vitamin C varied from 122.4 to 193.2 mg/100 g fresh weight (FW), while concentration of invert sugars ranged from 6.3% to 11.1%. The highest amounts of total phenolics and anthocyanins were detected in variety Ometa (278.9 mg of gallic acid equivalents per 100 g of FW [mg GAE/100 g FW] and 135.4 mg/100 g, respectively). Quantitative analyses of anthocyanin aglycones in berries were performed using high-performance liquid chromatography, and delphinidin was found to be dominant compound in 11 varieties. Total phenolics and anthocyanins contents decreased during the processing of berry fruits to juices, and the reduction of anthocyanins was more pronounced, 12%–80%. The radical scavenging activity of black currant juices was investigated by 1,1-diphenyl-2-picrylhydrazyl, and the IC50 value ranged from 1.9 to 4.0 mg/mL. Our results also showed that freezing as a way of preservation and storage could save important phytochemicals and health benefits of berries and berry juices. The amount of total phenolics in berries increased during 1 year of storage by 46.09%–171.76% and in juices by even 107.58%, while the amount of total anthocyanins in berries and juices decrease by 5.63%–52.76% and 13.04%–36.82%, respectively.

      • 구순 구개열 환자의 성장후 측모형태에 관한 두부계측방사선학적 연구

        장익준,손우일,송재철,진병로 영남대학교 기초/임상의학연구소 2001 Yeungnam University Journal of Medicine Vol.18 No.1

        Background: Cleft lip and palate deformity have unknown patterns of maxillofacial growth and development. The maxillofacial growth can be affected either by congenital or environmental factors such as infection and trauma. Surgical repair of cleft lip and palate may interfere the subsequent growth and development of maxillofacial region. The purpose of this study is to evaluate the characteristics of maxillofacial growth patterns in adult cleft lip and palate patients. Materials and Methods: The material for this study consisted of 17 adult male patients with cleft lip and palate. Cephalometric tracing and measurements were done by one investigator. The relationship between 17 cleft lip and palate patients and Korean norms were evaluated statistically Results: There were statistically differences in Na. perpendicular to point A, SNA angle, effective maxillary length, maxillofacial differencial, Wit's appraisal and upper incisor to point A(p<0.01). Pogonion to Na. perpendicular also statistically differed(p<0.05). Other measurements didn't statistically differ. Conclusion: It was evident that in adult cleft lip and palate patients, maxilla was retruded and short. Careful cleft lip and palate repair and treatment are recommended for facilitating normal growth of maxilla.

      • 황해난류수와 황해저층냉수

        김태희,방익찬 제주대학교 1991 논문집 Vol.32 No.-

        첫째, 황해의 수온과 염분분포에는 겨울철에 큰 확산의 효과가 나타나는 반면 여름철에는 확산의 효과를 거의 볼 수 없다. 그 이유는 겨울에는 황해난류수가 북상하는 반면 여름에는 황해저층냉수가 남하하기 때문이다. 결국, 황해에는 확산의 효과가 크기는 하나 황해의 특성분포에 근본적인 영향을 주는 것은 해수의 흐름이기 때문에, 황해의 특성분포로 부터 겨울철 황해난류수의 북상과 여름철 황해저층냉수의 남하를 확인할 수 있다. 둘째, 황해난류수의 북상과 황해저층냉수의 남하는 연관을 가진다. 겨울철에는 황해난류수의 북상이 강하면 여름철에 황해저층냉수의 남하세력이 약화되고 반대로 겨울철에 황해난류수의 북상이 약하면 여름철에 황해저층냉수가 겨울철에 형성된다. 이것은 황해저층냉수가 겨울철에 형성된다는 견해를 뒷받침해 주며 황해의 열 공급이 황해난류수에 의해 결정된다는 것을 아울러 보여준다. In winter, warmer temperatures are extended up to the middle of the Yellow Sea while higher salinities stay only in the southern Yellow Sea. At a first glance, it looks like the effects of diffusions. in the absence of the northward Yellow Sea Warm Current. However. in order to explain the weak diffusions in summer, the advections are necessary : the northward Yellow Sea Warm Current in winter and the southward Yellow Sea Bottom Cold Water in summer. The two flows are related. When the Yellow Sea Warm Curent is strong in winter, the Yellow Sea Bottom Cold Water becoms weak in the follwing summer, and vice versa. This supports the opinion that the Yellow Sea Bottom Cold Water are formed in the preceding winter. It also suggests that the heats in the Yellow Sea are supplied mainly by the Yellow Sea Warm Current.

      • KCI등재
      • KCI등재

        매복 하악 제3대구치의 외과적 발거에 영향을 미치는 방사선학적 변수

        김동현,박성빈,장익준,송재철,진병로 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3

        Purpose : The purpose of this study was to determine radiologic variables affecting extraction of impacted mandibular third molar. Materials and Methods : This study was investigated on 44 consecutive extractions of unilateral impacted mandibular third molars (Male;34, Female;10, Mean age;24.98, Age range;19-35). Fourteen radiologic variables, which were actual value except only one, were evaluated to establish their relation to the operation time. The Pearson correlation coefficient and Stepwise procedures for regression analysis were carried out. Results : Eight variables (depth, angulation, ramus width, relationship to the second molar, distal ramus depth, mesial ramus depth, mesial periodontal ligament width and follicle) showed a statistically significant relation to the operation time(Pearson correlation coefficient, p<0.05) . Two variables, depth and mesial periodontal ligament width, showed the most powerful and just relation to the operation time(r2 = 0.349, p<0.05). Conclusion : This study shows that our results can help general practioner to estimate the operation time of extraction of impacted mandibular third molars by measuring two radiologic variables ; depth and mesial periondontal ligament width.

      • SCIESCOPUSKCI등재

        APE1/Ref-1 Promotes the Effect of Angiotensin II on $Ca^{2+}$-Activated $K^+$ Channel in Human Endothelial Cells via Suppression of NADPH Oxidase

        ics, College of Medicine, Cardiovascular and Metabolic Disease Research Center, Medical Research Center, Inje University,Park, Won-Sun,Ko, Eun-A,Jung, In-Duk,Son, Youn-Kyoung,Kim, Hyoung-Kyu,Kim, Na-R 대한약학회 2008 Archives of Pharmacal Research Vol.31 No.10

        The effects of angiotensin II (Ang II) on whole-cell large conductance $Ca^{2+}$-activated $K^+$ ($BK_{Ca}$) currents was investigated in control and Apurinic/apyrimidinic endonuclease1/redox factor 1 (APE1/Ref-1)-overexpressing human umbilical vein endothelial cells (HUVECs). Ang II blocked the $BK_{Ca}$ current in a dose-dependent fashion, and this inhibition was greater in APE1/Ref-1-overexpressing HUVECs than in control HUVECs (half-inhibition values of $102.81{\pm}9.54\;nM$ and $11.34{\pm}0.39\;nM$ in control and APE1/Ref-1-overexpressing HUVECs, respectively). Pretreatment with the NADPH oxidase inhibitor diphenyleneiodonium (DPI) or knock down of NADPH oxidase (p22 phox) using siRNA increased the inhibitory effect of Ang II on the $BK_{Ca}$ currents, similar to the effect of APE1/Ref-1 overexpression. In addition, application of Ang II increased the superoxide and hydrogen peroxide levels in the control HUVECs but not in APE1/Ref-l-overexpressing HUVECs. Furthermore, direct application of hydrogen peroxide increased $BK_{Ca}$ channel activity. Finally, the inhibitory effect of Ang II on the $BK_{Ca}$ current was blocked by an antagonist of the Ang II type 1 ($AT_1$) receptor in both control and APE1/Ref-1-overexpressing HUVECs. From these results, we conclude that the inhibitory effect of Ang II on $BK_{Ca}$ channel function is NADPH oxidase-dependent and may be promoted by APE1/Ref-1.

      • KCI등재

        Evaluation of Common Building Wall in See-Through-Wall Application of Ultra-wideband Synthetic Aperture Radar

        Ic-Pyo Hong,Nguyen Trung Kien 대한전기학회 2021 Journal of Electrical Engineering & Technology Vol.16 No.1

        This paper presents the reproduced images of various objects from synthetic aperture radar (SAR) technique with ultrawideband (UWB) signals to evaluate the performance of common building walls in the see-through-wall capability regarding security applications, object along with human detection. The walls were designed from four materials, i.e., drywall, wood, insulation, and brick, which are used in real environments. The images of the objects behind the walls were performed using the commercial UWB radar with 2.2 GHz frequency bandwidth, 2 ns of pulse width, 10 MHz of internal repetition frequency, as well as an image reconstruction algorithm. From the measurement result, the insulated wall degraded the SAR image quality. Consequently, a material that enhance the UWB signal as Frequency Selective Surface should be considered to enable SAR for disaster applications.

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