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정만석,곽현철,석호태 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1
Generally, Educational Buildings was selected a direction, plan and scale of building according to the figure of a site. However, In the result. The selection was spent more energy and made every effort to achieve the Thermal Comfort. In the Evaluation of Energy Performance, You must consider whether it will be worthwhile. In this study, we found a difference of Energy Consumption changes according to corridor style, direction, vertical and horizontal location, and roof-space by using DOE-2.1E energy simulation program. Based on this simulation results, found a probability of reducing energy consumption in educational buildings.
하영철,정수일,곽윤근,신현익,하헌정,김익환,김석만 金烏工科大學校 1999 論文集 Vol.20 No.-
This paper presents the future direction of the development and maintenance of the urban park of the Kumi city. The direction was obtained by analyzing the evaluation results on the satisfaction level of park use and the park image of the park users. The analysis results are as follows. 1) It turns out that the rest and accommodation facilities are the major facilities that uplifts the total image of the park. 2) Among the park images, the image on the pleasantness was the major image, related with the satisfaction on the park equipments. 3) The social class, who gave a bad score on the above equipments and images, is a low-aged class, who is a white class with high income as well. Therefore, it is suggested that the park maintenance plan, with emphasis on the class, is an important task.
[ $\beta$ ]-Secretase (BACE1) Inhibitors from Pomegranate (Punica granatum) Husk
Kwak Hye-Min,Jeon So-Young,Sohng Bang-Ho,Kim Jong-Guk,Lee Jin-Man,Lee Kyung-Bok,Jeong HyunHee,Hur Jong-Moon,Kang Young-Hwa,Song Kyung-Sik The Pharmaceutical Society of Korea 2005 Archives of Pharmacal Research Vol.28 No.12
In the course of screening for anti-dementia agents from natural products, two $\beta$-secretase (BACE1) inhibitors were isolated from the husk of pomegranate (Punica granatum) by activity-guided purification. They were identified as ellagic acid and punicalagin with $IC_{50}$ values of 3.9 $\times$$10^{-6}$ and 4.1$\times$$10^{-7}$ M and Ki values of 2.4$\times$$10^{-5}$and 5.9$\times$$10^{-7}$ M, respectively. The compounds were non-competitive inhibitors with a substrate in the Dixon plot. Ellagic acid and punicalagin were less inhibitory to $\alpha$-secretase (TACE) and other serine proteases such as chymotrypsin, trypsin, and elastase, thus indicating that they were relatively specific inhibitors of BACE1.
高速道路 路盤의 軟弱地盤 改善工法에 關한 硏究 : Sand Drain 工法에 依한
郭鍾現,朴春洙,李會晩 大田工業高等專門學校 1969 論文集 Vol.5 No.-
If were construct structures or bank on the soft-clay stratum. the settlement would keep on over a long time in future. Therefore, there would happer meor venience in constructing structures, and the failures of them result from the differential. When we are to make use to the sand drain in order to improve such a soft-clay stratum. the first object consists in decreasing the subsequent differential to the minimum by bringing about the differential rapidly, which should take place in future, within the shortest time. The second object is to get the strength of the stratum in a hurry, which is necessary to the safety of the structures. But it is common to try to get the effects of both of these at the same time. This research is about the effects of sand drain which depends upon the boundary condition of the soft-clay stratum. And as the result of the indoor experiments, in case of setting up the sand pile, changing the diameter of the settlement, comparing and examming the practical measures and theoretical ones. The results of them are as follows: a. The consolidation settlement is more promoted in a double drainage than in a single one. b. The proportion of the diameter of the sand pile against the effective diameter of soil cylinder, that is, "n_" is large in the amount of the consolidation settlement of a small test ward. c. Compared with the occasion when we did not set up the sand pile, there arose 1.83 times consolidation settlement in the single drainage, 1.38 times in a double one, and 1.65 times at the average. d. In the same value of "n_", the amount of the consolidation settlement appeared larger when we make the effective diameter of soil cylinder small. e. The amount of the consolidation settlement of the actual survey appeared as 70% of the theoretical one. f. The treatment in which the effects of consolidation settlement of the sand drain appeared the most ideal, is B_1-9-3 in a single drainage and B_2-9-3 in a double one. g. After the conclusion of the settlement, the horizontal distribution of moisture content increased in proportion to the effective radius of soil cylinder from the sand pile.
Clinical outcomes in pediatric patients with normal renal histopathology
Kwak Naeun,박민지,Jang Hea Min,Baek Hee Sun,이상인,Han Man-Hoon,Kim Yong-Jin,Cho Min-Hyun 대한신장학회 2022 Kidney Research and Clinical Practice Vol.41 No.1
Background: There have been some cases where abnormal histopathologic findings could not be found in the kidney could even with proper specimen collection through percutaneous renal biopsy (PRB) in accordance with its indication. We analyzed the incidence and clinical outcomes of children who showed normal histopathological findings in their PRBs.Methods: The medical records of 552 pediatric subjects who underwent PRB between 2005 and 2016 were reviewed. Twenty-six subjects were excluded because allograft biopsy was performed in nine subjects, and the age at biopsy was greater than 18 years in 17 subjects. Finally, 526 subjects were enrolled in this study.Results: Of the 526 pediatric patients, 32 (6.1%) showed no histopathological abnormalities in their PRBs. The male-to-female ratio of the patients was 1.9:1, and the mean ages at the first visit and at biopsy were 10.6 ± 4.1 and 11.4 ± 3.8 years, respectively. In accordance with the biopsy indications, recurrent gross hematuria showed the highest incidence rate, but combined hematuria and proteinuria had the lowest incidence rate regarding normal renal histopathology among all the subjects. At a mean follow-up of 35.5 ± 23.6 months, urinary abnormalities had improved in more than 50% of the subjects with normal renal histopathology, and none of the patients showed progression to end-stage renal disease or required rebiopsy due to symptom worsening during the follow-up period.Conclusion: The clinical outcomes of children with normal PRB histopathologic findings are generally good. Further studies to evaluate their long-term outcomes are needed.