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Case Report : Langerhans Cell Histiocytosis Presenting as Brown Lichenoid Patches
Hyuk Kwon,Jang Hyun Lee,Sung Keun Kim,Young Lip Park,Jong Suk Lee,Moon Kyun Cho 대한피부과학회 2009 Annals of Dermatology Vol.21 No.3
Langerhans cell histiocytosis (LCH) is related diseases characterized by proliferation of Langerhans cell with involvement of bone, skin, lung and other organs. LCH usually occurs in childhood and are presented as multiple small papules or eczematoid lesion mostly. We report a 50-year-old man with 3 brown lichenoid patches on left dorsal foot. He was diagnosed pulmonary LCH 5 years ago. Typical LC cells on skin lesion and CD1 complex positive staining confirm the diagnosis of LCH. We consider brown lichenoid patches may be a previously unreported cutaneous presentation in cutaneous or multisystem LCH. (Ann Dermatol 21(3) 277~280, 2009)
Upgrade and Modification of Fuel Handling Equipment at Operating Nuclear Power Plants
Sang-Gyoon Chang,Jun-Kyu Lee,Sung-Hwan Kim,Won-Bae Park,Min-Gyu Kim,Dae-Hyuk Kwon 한국방사성폐기물학회 2023 한국방사성폐기물학회 학술논문요약집 Vol.21 No.1
The purpose of this study is to provide technical issues in upgrade and modification of fuel handling equipment at operating nuclear power plants. The improvement for safety function and performance enhancement of fuel handling equipment has been going on for 20 years since the early 2000’s. This improvement is recently focused on the replacement of components through the performance analysis and the operation and maintenance plan based on replacement cycle of its component. Additionally, it is required to secure spare parts so that it can be operated at all times with compatibility and standardization to other domestic nuclear power plants. The fuel handling equipment is consisted of refueling machine, upender and carriage of fuel transfer system, spent fuel handling machine, new fuel elevator and various tools, and the equipment are linked in systematic interlocks. Fuel handling is a critical task during a nuclear power plant refueling outage. Even minor component defects may stop operation of the whole system and have a significant impact on the overall system process. To achieve this goal, major components that are expected to be replaced for reliable operation are summarized as follows; 1) motor assembly with AC servomotors and driver for bridge, trolley and hoist of refueling machine and spent fuel handling machine, 2) winch motor and drive for upender and carriage of fuel transfer system, 3) operator control console with a HMI PC base PLC (Programmable Logic Controller) control system, 4) positioning and load weighing sensors such as an encoder and a load cell with its support for periodic calibration and maintenance, 5) main power drapped style festoon cable assembly for bridge of refueling machine, 6) pneumatic control assembly for gripper operation of refueling machine, 7) active components (e. g., air motor, hydraulic cylinder and limit switch) to be removable and reinstallable without requiring the water level to be lowered. It is advisable to utilize such various information as it can help to improve reliability of fuel handling as a critical path in upgrade and modification of fuel handling equipment at operating nuclear power plants.
Prognostic implication of metastatic lymph node ratio in node-positive rectal cancer
Sang-Min Lee,Jong-Seok Shin,Hong-Jo Choi,Ki-Jae Park,Young-Hoon Roh,Hyuk-Chan Kwon,Mee-Sook Roh,Hyung-Sik Lee,Choongrak Kim 대한외과학회 2011 Annals of Surgical Treatment and Research(ASRT) Vol.80 No.4
Purpose: The aim of this study was to evaluate the prognostic significance of the ratio between metastatic and examined lymph nodes (LNs) in patients with stage Ⅲ rectal cancer. Methods: A review was made of 175 (male, 98) patients with stage Ⅲ rectal cancer of R0 resection. LN disease was stratified both by the American Joint Committee on Cancer/International Union Against Cancer nodal classification (pN) and by quartiles of the lymph node ratio (LNR). Disease-free survivals (DFS) were made using Kaplan-Meier curves and assessed by the log rank test and multivariate analysis was performed using the Cox proportional hazards model. Results: Patients ranged in age from 29 to 83 (median, 60) years with median follow-up of 47 months (range, 13 to 181 months). months. There was a significant correlation between the number of metastatic LNs and the LNR (r = 0.8681, P < 0.0001). Cut-off points of LNR quartiles best to separate patients with regard to 5-year DFS were between quartile 2 and 3, and between 3 and 4 (LNR1, 2, and 3); the 5-year DFS according to such stratification was 89.6%, 55.8%, and 18.2% in LNR1, 2, and 3, respectively (P < 0.0001). Cox model identified the LNR as the most significant independent prognostic covariate; LNR2 showed 3.6 times (95% confidence interval [CI], 1.682 to 7.584; P = 0.0009) and LNR3, 18.7 times (95% CI, 6.872 to 50.664; P < 0.0001) more risky than LNR1. Conclusion: This study suggests that ratio-based LN staging, which reflects the number of LNs examined and the quality of LN dissection, is a simple and reliable system for prognostic LN stratification in patients with stage Ⅲ rectal cancer.
Prevalence and Clinical Characteristics of the Metabolic Syndrome in Middle-Aged Korean Adults
( Hyuk Sang Kwon ),( Yong Moon Park ),( Hye Jung Lee ),( Jin Hee Lee ),( Yoon Hee Choi ),( Seung Hyun Ko ),( Jung Min Lee ),( Sung Rae Kim ),( So Young Kang ),( Won Chul Lee ),( Myung Sook Ahn ),( Jae 대한내과학회 2005 The Korean Journal of Internal Medicine Vol.20 No.4
Background : The aim of this study was to analyze the prevalence and clinical characteristic of the metabolic syndrome of adults, over 40 years old, living in Korea. Methods : This study was carried out for 2 years, 2003-2004, on total 5,330 individuals (2,197 men and 3,133 women) selected by the stratified random cluster sampling among adults over 40 years old. Metabolic syndrome was defined based on both the NCEP-ATP III criteria and Modified ATP III criteria applying the WHO-APR (Asian Pacific Region)`s abdominal obesity criteria (waist circumference > 90 cm in men, 80 cm in women) instead of NCEP-ATP III criteria. Results : Using NCEP-ATP III criteria, the age-adjusted overall prevalence of metabolic syndrome was 24.8% (17.6% in men, 30.0% in women). Age-adjusted overall prevalence of metabolic syndrome as defined by modified-ATP III criteria was 34.3% (26.3% in men, 40.1% in women). The prevalence of metabolic syndrome for each age group (40-49, 50-59, 60-69, ≥ 70) in men was as follows: 18.8%, 17.4%, 18.3%, 14.5%. In women: 22.3%, 32.7%, 39.9%, 39.3%. The prevalence of hypertriglyceridemia (triglycerides ≥ 1.7 mmol/l) was well correlated with the changing pattern of the prevalence of metabolic syndrome both in men and women. Conclusions : The peak age of metabolic syndrome in men was age 40 through 49, and the prevalence decreased with aging. Therefore, early intervention for risk factors of metabolic syndrome might be required in men. On the other hand, prevention for cardiovascular disease will be needed for perimenopausal women due to considerably increased prevalence in the age 50 through 59.
Sung Hyuk Song,Gi Hyeong Ryu,Jin Woo Park,Ho Jun Lee,Ki Yeun Nam,Hyojun Kim,Seung Yeon Kim,Bum Sun Kwon 대한재활의학회 2016 Annals of Rehabilitation Medicine Vol.40 No.1
Objective To compare the long-term effect and safety of an epidural steroid injection in spinal stenosis patients, with or without local anesthetics.Methods Twenty-nine patients diagnosed with spinal stenosis were included and randomly divided into two groups. Translaminar epidural and selective nerve root spinal injection procedures were performed using steroids mixed with local anesthetics or normal saline. The effects of spinal injection procedures were measured with visual analogue scale (VAS) and functional rate index (FRI). These measurements were performed before injection, at 1 month after injection and at 3 months after injection. The occurrence of side effects was investigated each time.Results The VAS and FRI scores were significantly reduced in both the local anesthetics group and normal saline group at 1 and 3 months after the injection. However, there was no significant difference in VAS and FRI score reduction between the two groups each time. Side effects are not noted in both groups.Conclusion The spinal injection procedures using steroids mixed either with local anesthetics or normal saline have an effect in reducing pain and improving functional activities. However, there was no significant difference between the two groups in relation to side effects and the long-term effects of pain and function.