2002년 부산아시아게임과 부산체육의 백년대계

하형주,이동갑 東亞大學校 附設 스포츠科學硏究所 1995 스포츠科學硏究論文集 Vol.13 No.-

To construct main-stadium and physical education-related facilities at kang-seo area is considered essential result when we ultimately watch the problem which land of scale, proportion development of city, geographic or financial condition, safety and security, and guarantee of cultural place to give next generation. We sure that Pusan Asian Games for the unity, cooperation, peace promotion of 3 billion Asian successfully will be held. and 2002 Asian Games, simply, is not at once physical education event but occupy the basic facility of city and excellent strategic dimension which prepare decisive opportunity of 21st century Pusan prosperity also, We must not to neglect comprehensive public opinion. 2002 Asian Games for the successful hold, epoch-making opportunity of Pusan Properity, cultural level promotion of Pusan citizen, will be construct main stadium, dormitory for the athletes, press center, broadcasting center, and so forth and Pusan Asian Games will be achieve globalization.

쉘 요소를 이용한 박판 성형 공정 해석의 산업현장 적용에 관한 연구

정동원,고형훈,문원섭 제주대학교 공과대학 첨단기술연구소 2005 尖端技術硏究所論文集 Vol.16 No.2

Finite element analysis of sheet metal forming process is generally carried out by the explicit and implicit time integration method. And membrane, shell and continuum element are applied to finite element analysis. Membrane analysis can not provides sufficient information for the process which involve considerable bending effects. Shell element allows the consideration of bending effects, but involves too much computational time. In order to estimate in sheet metal forming processes used Auto-Form software using static-implicit method and shell element. Result, by applying this to an industrial site the productivity improvement and cost reduction etc. effect able was predicted.

청소년기 여학생들의 자살에 대한 태도 및 자아상에 관한 연구 : FOCUSED ON INDUSTRIAL AND CULTURAL WOMEN'S HIGH SCHOOL FACTION 실업계·인문계 여고생을 중심으로

장동원,김봉준,김준형 대한소아ㆍ청소년정신의학회 1999 소아청소년정신의학 Vol.10 No.2

탈지 및 지방산 첨가가 쌀전분 겔의 텍스쳐에 특성에 미치는 영향

최형택,최동원 기전여자대학 1991 論文集 Vol.11 No.-

Effects of defatting and reincorporation with fatty acid on the textural characteristics of rice starch gel were investigated. Hardness of cooked rice starch gel was increased by defatting during storage periods. Among the textural parameters, hardness showed significant differences. Retrogradation rate of defatted rice starch gel was faster than other starch gels.

Metoclopramide가 휜쥐의 血壓에 미치는 影響

임동윤,최동준,김규형,최철희,박재윤,문재규,김문석,황두환 中央醫學社 1988 中央醫學 Vol.53 No.9

Influences of metocopramide (MCP), which is a seletive dopaminergic antagonist, on blood pressure of the rat and its mechanism of action were investigated in the present study. MCP administered into a femoral vein of the rat caused markedly a dose-related fall in blood pressure followed by secondary transient pressor response. The depressor action evoked by MCP was not blocked by pretreatment of atropine or chlorisondamine, while the pressor action was inhibited significantly. Prazosin treatment reduced markedly both of depressor and pressor induced by MCP. MCP-evoked pressor action was not affected by clonidine, but the depressor response was attenuated significantly. Debrisoquin treatment made the inhibited response to MCP-induced pressor response, while did not affect the depressor action. Both of pressor and depressor responses evoked by MCP were not influenced by cyproheptadine. The hypertensive activity induced by nor epinephrine was weakened markedly by the infusion of MCP (1.50 mg/kg/30min.), but the pressor action evoked by dopamine not affected. These experimental data suggest that MCP produces biphasic responses (depressor and pressor) in blood pressure of the rat, and that the hypotensive activity is due to adrenergic alpha-receptors blockade, and that pressor activity is exerted through stimulation of cholinergic nicotinic receptors in autonmic ganglia.

牧丹皮가 Collagen 誘發 關節炎에 미치는 影響

金東赫,宋峰根,金炯均 한국전통의학연구소 1997 한국전통의학지 Vol.7 No.2

류마티스관절염은 활막관절 부위의 만성 염증을 특징으로하며 병이 진행될에 따라 이환된 관절의 연골 및 골과 관절주위 연체조직의 파괴를 초래하는 전신성 자가면역질환이다. 전세계에 걸쳐서 주로 젊은층에서 발병하며 전 인구의 약 2-4%가 이환되는 것으로 알려진 류마티스관절염의 병인에 대하여는 아직도 완전히 규명되지 못하고 있으며,이 질병을 완치 시키거나 질병의 질행을 막을 수 있은 치료법이 정리되지 않은 실정이다. 牧丹皮는 淸熱凉血 活血祛瘀의 효능이 있어 임상적으로 발열,도한,월경불순등 이나 급성충수염 또는 跌打瘀血 등에 응용되어 왔으며 최근에는 진정,최면,진통작용과 항염 및 항알레르기 작용 등이 보고되고 있고 adjuvant 관절염에서 염증반응을 억제하는 것으로 보고되고 있다. 목단피가 콜라겐유발관절염(CIA)에 미치는 영향을 알아보기 위하여 bovine type II collagen을 랫트의 꼬리에 주사하고 목단피를 투여하여 CIA의 유발과정중의 면역학적 변화에 미치는 영향에 대하여 관찰하였다. 그 결과 목단피는 생체내와 생체외에서 담식세포에 의한 탐식능을 증가시켰으며 활막세포에 의한 반응산소중간물질 생성능을 감소시켰다. 또한 목단피는 림프구의 증식을 억제하였고,CD4+세포의 비율을 증가시키고 CD8+세포의 비율을 감소시켰다. 아울러 목단피는 요증 미tric oxide(NO)의 분비를 억제시켰고, 활막세포에서의 NO생성을 약간 증가시키는 효과를 보였으나 고농도의 목단피를 투여할 경우 다시 감소하는 결과를 보였다. 이상의 결과로 볼 때 collagen에 의한 관절염의 진행시 목단피의 투여는 면역반응을 조절하여 ROI와 NO의 생성을 억제하고 탐식능을 증가시켜 외부 항원에 대한 탐식을 효과적으로 하여 관절염의 진행을 완화시킨 것으로 생각되며,따라서 목단피는 류마티스관절염의 치료에 임상적으로 활용할 수 있을 것으로 사료된다. Rheumatoid arthritis(RA) is an autoimmune disorder characterized by a chronic inflammatory, proliferative polyarthritis with joint destruction. The disease occurs throughout the world. Most cases are common in young adult age, and 2-4% of the population are affected with female predominance. However the curative therapy of RA is not yet available, so the development of successful management is required. Moutan Cortex is an herb drug applied for such disease as fever, sweating, menstrual irregularity, acute appendicitis and trauma. Recently it is reported that Moutan Cortex has the antiinflammatory, antimicrobial and antihypertensive actions. It also has analgesic, sedative, and anticonvulsant effects. And it is reported to inhibil swelling of rat's paw and reduce arthritic joint swelling. So as to investigate the effects of Moutan Cortex on collagen-induced arthritis, its water extract was administered in the rat immunized by collagen and the immune responses were measured. The phagocytosis was increased in vivo and in vitro after administration of Moutan Cortex, which was strikingly increased after secondary immunization in vivo. Moutan Cortex decreased lhe reactive oxygen intermediate(ROI) formation and nitric oxide(NO) secretion in urine. While formation of reactive nitrogen intermediate was slightly increased after administration, it showed tendency of decrement in high dose. Moutan Cortex also inhibit lymphocytes proliferation. The ratio of CD4+ T cell was decreased and CD8+ T cell was increased. These results suggest that Moutan Cortex might inhibit arthritic changes by regulating immune response, inhibiting ROI and NO formation and increasing phagocytosis. So Moutan Cortex could be applied for the treatment of RA.

외상성 고막천공의 임상적 고찰

박형욱,김용기,임동명,윤신의,최봉남 朝鮮大學校 附設 醫學硏究所 1992 The Medical Journal of Chosun University Vol.17 No.1

The authors observed the clinical findings of 99 cases of traumatic drum perforations, who visited the department of otolaryngology of Chosun University Hospital and KwangYang Hospital from January 1988 to August 1991 The results obtained were as follows; 1) As an etiologic factor, the indirect trauma occupies the most case (79.8%), out of which the most cases is by assault. 2) Age distribution indicates 30 decade(32.3%) and 20 decade(26.3%) in the declining order and sex distribution indicates male to female is 1;1.3. 3) On occupation, house wife is the most frequently involved (35.4%) and officials & students are in the next order. 4) Most common complaint is Hearing impairment and the next complaints are tinnitus, otalgia and hemorrhage in order. 5) The most frequent site of perforation is the central portion of anteroinferior and posteroinfehor quadrant, Gradel in size and triangular shape are common. 6) Seasonal variation indicates that the most frequent occurence of perforation is on summer. 7) Average 25-35㏈ of hearing loss is most common, and the degree of hearing loss is well correlated with the size of perforation. 8) Two way of therapeutic measure are compared. a. stimulating with trichloroacetic acid ; spontaneously healing in 22 cases (22.2%) b. closing procedure with paper patch ; healing in 68 cases (68.7%) 9)The overall healing time is within 2 months in the most of case (about 80%).

롤포밍을 위한 박판 미세구조물 기초 연구

정동원,김형종,최두선,제태진,박재현 濟州大學校 海洋硏究所 2004 해양과환경연구소 연구논문집 Vol.28 No.2

Sandwich sheets consisting of two or more different material layers are widely used in various industries due to the diversity of properties they Possess, such as high electrical conductivity. high corrosion resistivity. high strength. etc. The production of sandwich sheets by a rolling process. which is a more efficient and economical approach compared to other types of Processes. has become an increasingly important subject of study. In this study, the focus of the analysis is to evaluate stress and strain of the micro structure by the roll forming.

연소유동해석 프로그램의 개발

申東信,李炯來 弘益大學校 科學技術硏究所 1996 科學技術硏究論文集 Vol.7 No.1

We developed a simulation program using boundary fitted coordinates to simulate flow fields combustion. The program is based on finite volume method and uses collocated grid system. The primitive cartesian velocities are dependent variables. We used upwind scheme for convection terms and SIMPLE for pressure. For turbulence models, we considered standard k-εmodel. We used CGM to solve the linear system of equations for pressure and SIP for other nonlinear systems. The combustion model was the first order irreversible chemical reaction. Lewis number was assumed as 1. The probability density function for conserved scalar are assumed as clipped gaussian distribution. We simulated turbulent diffusion flame after the bluff-body and compared with experimental data. The result showed that the flow field has two recirculation region. The comparison showed good agreement between the simulation data and experimental data.

Homocysteine-thiolactone 이 유발시키는 소 혈관내피세포의 손상효과

유동찬,김보은,전가영,권오형,지광환 금오공과대학교 2007 論文集 Vol.28 No.-

The homocysteine-thiolactone, a reactive metabolic compound of homocysteine has been implicated in human cardiovascular diseases. The increasing of total plasma homocysteine concentration lead to homocystinuria, which may cause to elevate the concentration of homocysteine-thiolactone in the blood serum. It might be one of the risk factor which is responsible for the development of several vascular diseases. The present study is to demonstrate the harmful effect of homocysteine-thiolactone induced on calf pulmonary artery endothelial (CPAE) cells. CPAE were cultured in RPMI1640 medium supplemented with 10% FBS. CPAE were grown in humidified atmosphere of 5% C₂ in air at 3TC. Cells cultured with homocysteine-thiolactone at concentrations ranging from 0.1mM, lmM, 5mM and l0mM (dissolved in dH₂O). After incubation, cells were stained with MTT. Cell viability was evaluated under the UV-visible absorbance at 540nm. Cells viability was significantly decreased by increasing the concentration of homocysteine-thiolactone, Our data provide the evidence to understand the effect of homocysteine-thiolactone on the cardiovascular system.