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Bilingual Multiword Expression Alignment by Constituent-Based Similarity Score
( Hyeong-won Seo ),( Hongseok Kwon ),( Min-ah Cheon ),( Jae-hoon Kim ) 한국정보처리학회 2016 Journal of information processing systems Vol.12 No.3
This paper presents the constituent-based approach for aligning bilingual multiword expressions, such as noun phrases, by considering the relationship not only between source expressions and their target translation equivalents but also between the expressions and constituents of the target equivalents. We only considered the compositional preferences of multiword expressions and not their idiomatic usages because our multiword identification method focuses on their collocational or compositional preferences. In our experimental results, the constituent-based approach showed much better performances than the general method for extracting bilingual multiword expressions. For our future work, we will examine the scoring method of the constituent-based approach in regards to having the best performance. Moreover, we will extend target entries in the evaluation dictionaries by considering their synonyms.
( Hyeong Cheon Park ),( Wan Sik Lee ),( Chang Hwan Park ),( Hyun Soo Kim ),( Sung Kyu Choi ),( Jong Sun Rew ),( Jae Hyuk Lee ),( Seok Lee ),( Sang Min Yum ),( Ho In Whang ),( Kyoung Won Yoon ),( Suck 대한소화기학회 2007 SIDDS Vol.9 No.-
Background Aims: Colorectal carcinoma (CRC) is known to be metastasized to the liver frequently and is the major cause of cancer-related death. Recent studies have identified several biomolecular alterations that influence prognosis after resection of liver matastases, including treatment-related and clinicopathologic factors. However, the relationship between the expression pattern of E- & N-cadherin and liver metastasis of CRC is poorly understood. Methods: The present study included 45 patients who underwent hepatic resection for colorectal hepatic metastasis. Immunohistochemical analysis of the expression of E- & N-cadherin protein was carried out for evaluating the metastatic potential of CRC. The methylation status of the E- & N-cadherin promoter was investigated by utilizing the methylation-specific polymerase chain reaction (MSP) assay in 45 patients. The correlation between E- & N-cadherin expression and clinicopathologic parameters was also analysed. Results: Abnormal E-cadherin expressions observed 42.2% (19/45) in primary cancers and 46.7% (21/45) in metastatic tumors. Abnormal N-cadherin expressions were noted 71.1% (32/45) in primary cancers and 82.2% (37/45) in metastatic tumors. Methylated alleles for E-cadherin presented 73.3% (33/45) in primary cancers and 64.4% (29/45) in metastatic tumors. Methylated alleles for N-cadherin presented 11.1%(5/45) in primary cancers and 8.9% (4/45) in metastatic tumors. Abnormal E-cadherin expression was significantly associated with hypermethylation of E-cadherin in primary CRC (P=0.036). Recurrence rate was significantly associated with liver mass size (>3 cm) and abnormal E-cadherin expression in liver (p=0.02). Survival rate was significantly associated with liver metastasis number (multiple)(p=0.01). Conclusions: Abnormal expression of E-cadherin was significantly associated with E-cadherin promoter methylation in CRC. Liver metastatic mass size and metastasis number were significantly associated with survival rate but E-cadherin, N-cadherin and methylation state in liver were not significantly associated with survival rate.
Shape-dependent antimicrobial activities of silver nanoparticles
Cheon, Ja Young,Kim, Su Jun,Rhee, Young Ha,Kwon, Oh Hyeong,Park, Won Ho DOVE MEDICAL PRESS 2019 INTERNATIONAL JOURNAL OF NANOMEDICINE Vol.14 No.-
<P><B>Purpose:</B> An important application of silver nanoparticles (Ag NPs) is their use as an antimicrobial and wound dressing material. The aim of this study is to investigate the morphological dependence on the antimicrobial activity and cellular response of Ag NPs.</P><P><B>Materials and methods:</B> Ag NPs of various shapes were synthesized in an aqueous solution using a simple method. The morphology of the synthesized Ag NPs was observed via TEM imaging. The antimicrobial activity of the Ag NPs with different morphologies was evaluated against various microorganisms (<I>Escherichia coli</I> [<I>E. coli</I>]<I>, Staphylococcus aureus</I> [<I>S. aureus</I>]<I>, Pseudomonas aeruginosa</I> [<I>P. aeruginosa</I>]). The antimicrobial activity of the Ag NPs was also examined according to the concentration in terms of the growth rate of <I>E. coli</I>.</P><P><B>Results:</B> The TEM images indicated that the Ag NPs with different morphologies (sphere, disk and triangular plate) had been successfully synthesized. The antimicrobial activity obtained from the inhibition zone was in the order of spherical Ag NPs > disk Ag NPs > triangular plate Ag NPs. In contrast, fibroblast cells grew well in all types of Ag NPs when the cell viability was evaluated via an MTT assay. An inductively coupled plasma mass assay showed that the difference in the antimicrobial activities of the Ag NPs was closely associated with the difference in the release rate of the Ag ions due to the difference in the surface area of the Ag NPs.</P><P><B>Conclusion:</B> The morphological dependence of the antimicrobial activity of the Ag NPs can be explained by the difference in the Ag ion release depending on the shape. Therefore, it will be possible to control the antimicrobial activity by controlling the shape and size of the Ag NPs.</P>
서형원 ( Hyeong-won Seo ),천민아 ( Minah Cheon ),김재훈 ( Jae-hoon Kim ) 한국정보처리학회 2015 한국정보처리학회 학술대회논문집 Vol.22 No.1
본 논문은 인공신경망(artificial neural network)의 한 종류인 자기조직화 지도(self-organizing map)를 이용하여 비교말뭉치(comparable corpora)로부터 이중언어사전(bilingual lexicon)을 자동으로 구축하는 방법에 대하여 기술한다. 일반적으로 우리가 대상으로 하는 언어 쌍마다 말뭉치 혹은 초기사전과 같은 언어 자원을 수집하고 그것을 필요에 맞게 가공하는 것은 매우 어려운 일이다. 이런 관점에서 볼 때, 비지도학습(unsupervised learning) 방법 중 하나인 자기조직화 지도를 이용하여 사전을 구축하면 다른 방법에 비해 적은 노력으로도 더 높은 성능을 얻을 수 있다. 본 논문에서는 한국어와 불어에 대하여 실험을 하였고, 그 결과 적은 양의 초기사전으로도 주목할 만한 정확도를 얻을 수 있었다. 향후 연구로는 학습 파라미터에 대해 좀 더 다양한 실험을 하고, 다른 언어 쌍으로의 적용 및 기존의 평가사전을 확장하여 더 많은 경우에 대해 실험하는 것을 들 수 있다.
Bilingual Multiword Expression Alignment by Constituent-Based Similarity Score
Seo, Hyeong-Won,Kwon, Hongseok,Cheon, Min-Ah,Kim, Jae-Hoon Korea Information Processing Society 2016 Journal of information processing systems Vol.12 No.3
This paper presents the constituent-based approach for aligning bilingual multiword expressions, such as noun phrases, by considering the relationship not only between source expressions and their target translation equivalents but also between the expressions and constituents of the target equivalents. We only considered the compositional preferences of multiword expressions and not their idiomatic usages because our multiword identification method focuses on their collocational or compositional preferences. In our experimental results, the constituent-based approach showed much better performances than the general method for extracting bilingual multiword expressions. For our future work, we will examine the scoring method of the constituent-based approach in regards to having the best performance. Moreover, we will extend target entries in the evaluation dictionaries by considering their synonyms.
클라우드 환경에서 제우스 Botnet 공격 유형 분석을 위한 클러스터링 방안 연구
배원일 ( Won-il Bae ),최석준 ( Suk-june Choi ),김성진 ( Seong-jin Kim ),김형천 ( Hyeong-cheon Kim ),곽진 ( Jin Kwak ) 한국인터넷정보학회 2017 인터넷정보학회논문지 Vol.18 No.1
최근 클라우드 컴퓨팅 기술의 발전으로 인해 다양한 분야에서 클라우드 컴퓨팅 기술이 활용되고 있다. 클라우드 서비스의 수요가 증가하는 반면에 클라우드 환경에서의 보안 위협은 증가하고 있으며 특히, 악성코드에 의한 공격을 통해 클라우드 환경 내 상호 연결되어 있는 호스트들이 감염 전파될 경우 다른 호스트의 리소스에도 영향을 끼쳐 개인정보 및 데이터의 삭제 등의 보안위협이 확산될 수 있다. 따라서 이러한 보안 위협에 대응하기 위한 악성코드 분석 연구가 활발히 진행되고 있다. 이에 따라, 본 논문은 클라우드 환경에서 발생하는 악성코드 분석을 위해 k-means 클러스터링 알고리즘을 이용한 제우스 봇넷의 공격 유형별 군집화 방안을 제안한다. 이는 클라우드 환경 내 발생되는 제우스 봇넷에 대하여 악성행위를 유형별로 군집화 함으로써 악성 유무를 판별할 수 있으며, 추후 클라우드 환경에서 발생할 수 있는 새로운 유형의 제우스 봇넷 공격 대응을 목표로 한다. Recently, developments in the various fields of cloud computing technology has been utilized. Whereas the demand for cloud computing services is increasing, security threats are also increasing in the cloud computing environments. Especially, in case when the hosts interconnected in the cloud environments are infected and propagated through the attacks by malware. It can have an effect on the resource of other hosts and other security threats such as personal information can be spreaded and data deletion. Therefore, the study of malware analysis to respond these security threats has been proceeded actively. This paper proposes a type of attack clustering method of Zeus botnet using the k-means clustering algorithm for malware analysis that occurs in the cloud environments. By clustering the malicious activity by a type of the Zeus botnet occurred in the cloud environments. it is possible to determine whether it is a malware or not. In the future, it sets a goal of responding to an attack of the new type of Zeus botnet that may occur in the cloud environments.
이달의 X선 : Clomifen 호르몬제 복용후 호흡곤란이 악화된 환자에서의 미만성 망상형 간질성 폐침윤
박형천 ( Hyeong Cheon Park ),김영삼 ( Young Sam Kim ),김세규 ( Se Kyu Kim ),정경영 ( Kyung Young Chung ),신동환 ( Dong Hwan Shin ),이홍렬 ( Hong Lyeol Lee ),장준 ( Joon Chang ),김성규 ( Sung Kyu Kim ),이원영 ( Won Young Lee ) 대한결핵 및 호흡기학회 1995 Tuberculosis and Respiratory Diseases Vol.42 No.4
포스터 전시 : 췌담도 ; 췌관을 따라 다발성으로 발생한 유두형 파터팽대부 선암 1예
천재희 ( Cheon Jae Hui ),조상형 ( Jo Sang Hyeong ),이우진 ( Lee U Jin ),박홍석 ( Park Hong Seog ),김성훈 ( Kim Seong Hun ),박상재 ( Park Sang Jae ),홍은경 ( Hong Eun Gyeong ),박중원 ( Park Jung Won ),김창민 ( Kim Chang Min ) 대한소화기학회 2003 대한소화기학회 추계학술대회 Vol.2003 No.-
<서론> 담관 및 파터팽대부에 발생하는 선암 중 유두형 선암은 담관 관강을 따라 다발성으로 발생하는 경우가 많고, 담관벽 침윤이 적어 비교적 예후가 좋은 것으로 알려져 있다. 유두형 선암이 담관과 췌관을 동시에 침범하는 경우는 매우 드물다. 또한 유두형 선암이 췌관에 다발성으로 발생하는 경우가 있긴 하지만 췌관 전체를 침범하는 경우는 드물다고 알려져 있다. 최근 저자들은 급성 췌장염으로 발현한, 전체 췌관을 따라 다발성으로 발생한 유두형 파터팽대부 선암
정상혈압 쥐와 고혈압 쥐에서 측뇌실에 주입한 Angiotensin II가 출혈 반응에 미치는 영향
이원정,김형진,박재식,박윤엽,천동욱,안동국 대한내분비학회 1993 Endocrinology and metabolism Vol.8 No.2
This study was performed to investigate the effects of central Ang Ⅱ on the hormonal responses to hemorrhage in conscious SHR and normotensive Wistar rats. Stainless steel cannula (22 gauge) was implanted stereotaxically in the lateral ventricle according to Paxinos' brain atlas. After a 5-day recovery period, bilateral femoral arteries were catheterized. All Surgical procedures were performed under pentobarbital anesthesia. On the following day, Ang Ⅱ (30 ng/ l) or artificial cerebrospinal fluid (aCSF) was infused into the lateral ventricle at a rate of 2㎕/min for 10 min. Acute hemorrhage (6㎖/㎏) was performed 5 minutes after infusion of Ang Ⅱ. Intracerebroventricular administration of Ang Ⅱ produced a dose-dependent increase in blood pressure and decrease in heart rate. SHR showed a greater pressor response to central Ang Ⅱ than Wistar rats. Central Ang Ⅱ increased plasma concentrations of vasopressin, aldosterone and ANP, but decreased plasma renin activity. Acute hemorrhage produced a increase inplasma concentrations of vasopressin, aldosterone and renin activity, but a decrease in ANP level. Central Ang Ⅱ facilitated the hemorrhage-induced increase in vasopressin release, but abolished the hemorrhage-induced increase in renin release. These results suggest that central Ang Ⅱ produces increase in blood pressure and facilitates hemorrhage-induced increase in plasma concentration of vasopressin. Therefore, these responses may contribute to facilitate the recovery from blood loss. (J Kor Soc Endocrinol 8: 141~148, 1993)